Cauda Equina Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: CDQ003 MIFTS: 22	Cauda Equina Neoplasm Categories: Cancer diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways Expand all tables

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Aliases & Classifications for Cauda Equina Neoplasm

MalaCards integrated aliases for Cauda Equina Neoplasm:

Name: Cauda Equina Neoplasm ¹² ¹⁵

Tumor of the Cauda Equina ¹²

Neoplasm of Cauda Equina ⁷²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4847

NCIt ⁵⁰ C5479

UMLS ⁷² C1263892

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Summaries for Cauda Equina Neoplasm

MalaCards based summary : Cauda Equina Neoplasm, also known as tumor of the cauda equina, is related to ependymoma and glomus tumor. An important gene associated with Cauda Equina Neoplasm is SYP (Synaptophysin), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include brain, and related phenotype is Increased viability.

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Related Diseases for Cauda Equina Neoplasm

Diseases related to Cauda Equina Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)

#	Related Disease	Score	Top Affiliating Genes
1	ependymoma	31.2	SYP ENO2
2	glomus tumor	30.7	SYP ENO2
3	spinal meningioma	30.5	ENO2 CHGA
4	rhabdoid tumor predisposition syndrome 1	30.3	WT1 SYP
5	small cell carcinoma	30.1	SYP ENO2 CHGA
6	paraganglioma	30.0	SYP ENO2 CHGA
7	benign ependymoma	30.0	SYP RBFOX3 ENO2
8	rhabdoid cancer	29.6	WT1 SYP EWSR1 ENO2
9	cauda equina intradural extramedullary astrocytoma	11.6
10	ganglioneuroblastoma	10.6	SYP ENO2
11	carotid body cancer	10.6	SYP ENO2
12	malignant sertoli cell tumor	10.6	SYP ENO2
13	sinonasal undifferentiated carcinoma	10.6	SYP ENO2
14	papillary tumor of the pineal region	10.5	SYP ENO2
15	extrahepatic bile duct adenocarcinoma	10.5	SYP ENO2
16	cutaneous ganglioneuroma	10.5	SYP ENO2
17	pancreatic somatostatinoma	10.5	SYP ENO2
18	middle ear adenoma	10.5	SYP ENO2
19	orbital cancer	10.5	SYP ENO2
20	sensory organ benign neoplasm	10.5	SYP ENO2
21	clear cell ependymoma	10.5	SYP ENO2
22	cerebellum cancer	10.5	SYP ENO2
23	central nervous system primitive neuroectodermal neoplasm	10.5	SYP ENO2
24	endometrial small cell carcinoma	10.5	SYP ENO2
25	cerebral neuroblastoma	10.5	SYP ENO2
26	astroblastoma	10.5	SYP ENO2
27	malignant teratoma	10.5	SYP ENO2
28	teratoma	10.5	SYP ENO2
29	subependymal glioma	10.5	SYP ENO2
30	pineal gland cancer	10.5	SYP ENO2
31	melanotic neuroectodermal tumor	10.5	SYP ENO2
32	cervical clear cell adenocarcinoma	10.5	SYP ENO2
33	angiomyoma	10.5	SYP ENO2
34	small cell osteogenic sarcoma	10.5	EWSR1 ENO2
35	mucinous ovarian cystadenoma	10.5	SYP ENO2
36	meningeal melanomatosis	10.5	SYP ENO2
37	bone benign neoplasm	10.5	SYP ENO2
38	malignant glandular tumor of peripheral nerve sheath	10.5	UCHL1 SYP
39	askin's tumor	10.5	EWSR1 ENO2
40	intraocular retinoblastoma	10.5	SYP ENO2
41	malignant peripheral nerve sheath tumor	10.5
42	connective tissue benign neoplasm	10.5	SYP ENO2
43	basaloid squamous cell carcinoma	10.4	SYP ENO2
44	subependymal giant cell astrocytoma	10.4	SYP ENO2
45	cystic teratoma	10.4	SYP ENO2
46	cerebral primitive neuroectodermal tumor	10.4	SYP ENO2
47	sertoli cell tumor	10.4	WT1 SYP
48	central nervous system benign neoplasm	10.4	SYP ENO2
49	optic nerve neoplasm	10.4	SYP ENO2
50	mixed cell type cancer	10.4	SYP ENO2

Graphical network of the top 20 diseases related to Cauda Equina Neoplasm:

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Symptoms & Phenotypes for Cauda Equina Neoplasm

GenomeRNAi Phenotypes related to Cauda Equina Neoplasm according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased viability	GR00386-A-1	9.17	CHGA EWSR1 RBFOX3 RPL24 SYP UCHL1

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Drugs & Therapeutics for Cauda Equina Neoplasm

Search Clinical Trials , NIH Clinical Center for Cauda Equina Neoplasm

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Genetic Tests for Cauda Equina Neoplasm

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Anatomical Context for Cauda Equina Neoplasm

MalaCards organs/tissues related to Cauda Equina Neoplasm:

⁴¹

Brain

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Publications for Cauda Equina Neoplasm

Articles related to Cauda Equina Neoplasm:

(show all 32)

#	Title	Authors	PMID	Year
1	Atypical Teratoid Rhabdoid Tumor of the Cauda Equina in a Child: Report of a Very Unusual Case. ³⁸	Shiflett JM...Saad AG	29346182	2018
2	Low-grade small round cell tumor of the cauda equina with EWSR1-WT1 fusion and indolent clinical course. ³⁸	Ud Din N...Perry A	25454478	2015
3	Malignant peripheral nerve sheath tumor of the cauda equina with craniospinal metastasis. ³⁸	Thomas JG...Gopinath SP	24986157	2014
4	Radiation-induced intradural malignant peripheral nerve sheath tumor of the cauda equina with diffuse leptomeningeal metastasis. ³⁸	Lau D...Orringer DA	25216401	2014
5	Intraspinal epidermoid tumor of the cauda equina region: seven cases and a review of the literature. ³⁸	Morita M...Iwasaki M	21602727	2012
6	Primary malignant peripheral nerve sheath tumor of the cauda equina with metastasis to the brain in a child: case report and literature review. ³⁸	Xu Q...Yang Z	22521675	2012
7	Metastatic malignant peripheral nerve sheath tumor of the cauda equina. ³⁸	Than KD...Pandey AS	21450470	2011
8	Peripheral primitive neuroectodermal tumor of the cauda equina in an elderly patient. Case report. ³⁸	Fabre E...Duffau H	16850960	2006
9	Radiotherapy-induced malignant peripheral nerve sheath tumor of the cauda equina. ³⁸	Amin A...Lehovsky J	15507791	2004
10	A rare case of metastatic renal cell carcinoma resembling a nerve sheath tumor of the cauda equina. ³⁸	Kubota M...Osato K	15177402	2004
11	Primary malignant peripheral nerve sheath tumor of the cauda equina in a child case report. ³⁸	Yone K...Komiya S	15001982	2004
12	Pathology case of the month. Tumor of the cauda equina. Paraganglioma of the cauda equina. ³⁸	Heard C...Albores-Saavedra J	14750748	2003
13	[Primitive neuroectodermal tumor of the cauda equina. Report of a case]. ³⁸	Martinez-Quinones JV...Hijosa M	11939094	2002
14	Malignant peripheral nerve sheath tumor of the cauda equina. ³⁸	Acharya R...Sehgal AD	11731882	2001
15	Primary primitive neuroectodermal tumor of the cauda equina. ³⁸	Isotalo PA...Robertson SJ	10987262	2000
16	Paraganglioma of the cauda equina. A case report and review of the literature. ³⁸	Bak J...Spannare B	8611199	1996
17	Sclerosing fibrous tumor of the cauda equina: a fibroblastic variant of peripheral nerve tumors? ³⁸	Hisaoka M...Rikimaru S	8213075	1993
18	Cauda equina tumor with ependymal and paraganglionic differentiation. ³⁸	Caccamo DV...Garcia JH	1612583	1992
19	[Mobile neurinoma of the cauda equina; a case report]. ³⁸	Satoh T...Date I	1944801	1991
20	Multiple neurilemmoma of the cauda equina. A case report. ³⁸	Shikata J...Shimizu K	1774600	1991
21	Hydrocephalus and cavernoma of the cauda equina. ³⁸	Ramos F...Jan M	2377272	1990
22	[Posterior hernia of the intervertebral disk combined with a tumor of the cauda equina]. ³⁸	Dolzhenko DA...Perfil'ev VM	2816195	1989
23	[Human chorionic gonadotropin-producing tumor of the cauda equina. Case report]. ³⁸	Takenaka N...Takamiya Y	2452369	1987
24	Elusive tumor of the cauda equina. Case report. ³⁸	Tavy DL...Hekster RE	3783245	1987
25	[Hydrocephalus aresorptivus and parkinsonism caused by a cauda ependymoma]. ³⁸	Kalff R	3997033	1985
26	[Papillary stasis caused by tumor of the cauda equina]. ³⁸	Bessiere E...Descamp F	5400737	1969
27	[Coccygodynia revealing a giant tumor of the cauda equina]. ³⁸	Chateau R...Perret J	5619326	1967
28	[Lumbosacral destruction caused by a giant tumor of the cauda equina (apropos of a case of operated ependymoma)]. ³⁸	Courson B...Lemercier G	5865018	1965
29	[Meningeal hemorrhages of spinal origin; diffuse subarachnoid hemorrhage following a tumor of the cauda equina]. ³⁸	FERNANDEZ G...PASEYRO P	13394901	1956
30	[Tumor of the cauda equina with papillary stasis]. ³⁸	JENTZER A...BONNANT M	13056402	1952
31	Gumma simulating tumor of the cauda equina. ³⁸	THOMPSON RG...PRESTON RH	15419389	1950
32	XI. Tumor of the Cauda Equina Removed by Operation: Recovery. ³⁸	Elsworth RC	17862052	1907

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Genes for Cauda Equina Neoplasm

Genes related to Cauda Equina Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	SYP	Synaptophysin	Protein Coding	14.79	DISEASES inferred ¹⁵
2	ENO2	Enolase 2	Protein Coding	14.68	DISEASES inferred ¹⁵
3	EWSR1	EWS RNA Binding Protein 1	Protein Coding	14.47	DISEASES inferred ¹⁵
4	UCHL1	Ubiquitin C-Terminal Hydrolase L1	Protein Coding	14.46	DISEASES inferred ¹⁵
5	WT1	WT1 Transcription Factor	Protein Coding	13.99	DISEASES inferred ¹⁵
6	CHGA	Chromogranin A	Protein Coding	13.95	DISEASES inferred ¹⁵
7	RBFOX3	RNA Binding Fox-1 Homolog 3	Protein Coding	13.07	DISEASES inferred ¹⁵
8	RPL24	Ribosomal Protein L24	Protein Coding	4.08	DISEASES inferred ¹⁵

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Variations for Cauda Equina Neoplasm

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Expression for Cauda Equina Neoplasm

Search GEO for disease gene expression data for Cauda Equina Neoplasm.

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Pathways for Cauda Equina Neoplasm

Pathways related to Cauda Equina Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.46	UCHL1 SYP RBFOX3 ENO2

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GO Terms for Cauda Equina Neoplasm

Cellular components related to Cauda Equina Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	neuron projection terminus	GO:0044306	8.62	UCHL1 SYP

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