Cauda Equina Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cauda Equina Neoplasm

MalaCards integrated aliases for Cauda Equina Neoplasm:

Name: Cauda Equina Neoplasm ¹¹ ¹⁴

Tumor of the Cauda Equina ¹¹

Neoplasm of Cauda Equina ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:4847

NCIt ⁴⁹ C5479

SNOMED-CT ⁶⁸ 126963001

UMLS ⁷¹ C1263892

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Summaries for Cauda Equina Neoplasm

MalaCards based summary: Cauda Equina Neoplasm, also known as tumor of the cauda equina, is related to glomus tumor and neurilemmoma. An important gene associated with Cauda Equina Neoplasm is ENO2 (Enolase 2), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include brain, and related phenotype is Increased viability.

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Related Diseases for Cauda Equina Neoplasm

Diseases related to Cauda Equina Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 270)

#	Related Disease	Score	Top Affiliating Genes
1	glomus tumor	30.3	SYP ENO2
2	neurilemmoma	30.3	SYP ENO2
3	islet cell tumor	30.2	SYP ENO2 CHGA
4	small cell carcinoma	30.0	SYP ENO2 CHGA
5	paraganglioma	29.9	SYP ENO2 CHGA
6	atypical teratoid rhabdoid tumor	29.9	SYP EWSR1
7	meningioma, familial	29.8	SYP EWSR1 ENO2
8	rhabdoid cancer	29.7	WT1 SYP EWSR1
9	ewing sarcoma	29.4	WT1 SYP EWSR1 ENO2 CHGA
10	rhabdomyosarcoma	29.0	WT1 SYP EWSR1 ENO2 CHGA
11	cauda equina intradural extramedullary astrocytoma	11.5
12	cauda equina neuroendocrine tumor	11.3
13	cauda equina syndrome	10.8
14	glanders	10.8
15	malignant peripheral nerve sheath tumor	10.5
16	testicular germ cell tumor	10.3
17	seminoma	10.3
18	testicular seminoma	10.3
19	bladder small cell carcinoma	10.2	SYP ENO2
20	malignant melanocytic neoplasm of the peripheral nerve sheath	10.2	SYP ENO2
21	anal neuroendocrine tumor	10.2	SYP ENO2
22	neuronal intestinal dysplasia, type b	10.2	SYP ENO2
23	optic nerve astrocytoma	10.2	SYP ENO2
24	cloacogenic carcinoma	10.2	SYP ENO2
25	pineal region teratoma	10.2	SYP ENO2
26	bile duct mucinous adenocarcinoma	10.2	SYP ENO2
27	partial cryptophthalmia	10.2	SYP ENO2
28	neurohypophysis granular cell tumor	10.2	SYP ENO2
29	cerebellopontine angle primitive neuroectodermal tumor	10.2	SYP ENO2
30	frontal lobe neoplasm	10.2	SYP ENO2
31	lipoma of spermatic cord	10.2	SYP ENO2
32	jejunal neoplasm	10.2	SYP ENO2
33	melanotic neuroectodermal tumor	10.2	SYP ENO2
34	paratesticular lipoma	10.2	SYP ENO2
35	prostate small cell carcinoma	10.2	SYP ENO2
36	mature teratoma	10.2	SYP ENO2
37	mature teratoma of the ovary	10.2	SYP ENO2
38	myoblastoma	10.2	SYP ENO2
39	sinonasal undifferentiated carcinoma	10.2	SYP ENO2
40	orbital cancer	10.2	SYP ENO2
41	cerebellar medulloblastoma	10.2	SYP ENO2
42	nasal cavity olfactory neuroblastoma	10.2	SYP ENO2
43	cystic basal cell carcinoma	10.2	SYP ENO2
44	lymphoepithelioma-like carcinoma	10.2	SYP ENO2
45	horner's syndrome	10.2	SYP ENO2
46	medulloepithelioma	10.2	SYP ENO2
47	cerebellum cancer	10.2	SYP ENO2
48	paranasal sinus cancer	10.2	SYP ENO2
49	cerebrovascular benign neoplasm	10.2	SYP ENO2
50	pineal gland cancer	10.1	SYP ENO2

Graphical network of the top 20 diseases related to Cauda Equina Neoplasm:

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Symptoms & Phenotypes for Cauda Equina Neoplasm

GenomeRNAi Phenotypes related to Cauda Equina Neoplasm according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased viability	GR00386-A-1	8.62	CHGA WT1

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Drugs & Therapeutics for Cauda Equina Neoplasm

Search Clinical Trials, NIH Clinical Center for Cauda Equina Neoplasm

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Genetic Tests for Cauda Equina Neoplasm

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Anatomical Context for Cauda Equina Neoplasm

Organs/tissues related to Cauda Equina Neoplasm:

MalaCards : Brain

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Publications for Cauda Equina Neoplasm

Articles related to Cauda Equina Neoplasm:

(show all 32)

#	Title	Authors	PMID	Year
1	Atypical Teratoid Rhabdoid Tumor of the Cauda Equina in a Child: Report of a Very Unusual Case. ⁶²	Shiflett JM...Saad AG	29346182	2020
2	Low-grade small round cell tumor of the cauda equina with EWSR1-WT1 fusion and indolent clinical course. ⁶²	Ud Din N...Perry A	25454478	2015
3	Malignant peripheral nerve sheath tumor of the cauda equina with craniospinal metastasis. ⁶²	Thomas JG...Gopinath SP	24986157	2014
4	Radiation-induced intradural malignant peripheral nerve sheath tumor of the cauda equina with diffuse leptomeningeal metastasis. ⁶²	Lau D...Orringer DA	25216401	2014
5	Intraspinal epidermoid tumor of the cauda equina region: seven cases and a review of the literature. ⁶²	Morita M...Iwasaki M	21602727	2012
6	Primary malignant peripheral nerve sheath tumor of the cauda equina with metastasis to the brain in a child: case report and literature review. ⁶²	Xu Q...Yang Z	22521675	2012
7	Metastatic malignant peripheral nerve sheath tumor of the cauda equina. ⁶²	Than KD...Pandey AS	21450470	2011
8	Peripheral primitive neuroectodermal tumor of the cauda equina in an elderly patient. Case report. ⁶²	Fabre E...Duffau H	16850960	2006
9	Radiotherapy-induced malignant peripheral nerve sheath tumor of the cauda equina. ⁶²	Amin A...Lehovsky J	15507791	2004
10	A rare case of metastatic renal cell carcinoma resembling a nerve sheath tumor of the cauda equina. ⁶²	Kubota M...Osato K	15177402	2004
11	Primary malignant peripheral nerve sheath tumor of the cauda equina in a child case report. ⁶²	Yone K...Komiya S	15001982	2004
12	Pathology case of the month. Tumor of the cauda equina. Paraganglioma of the cauda equina. ⁶²	Heard C...Albores-Saavedra J	14750748	2003
13	[Primitive neuroectodermal tumor of the cauda equina. Report of a case]. ⁶²	Martinez-Quinones JV...Hijosa M	11939094	2002
14	Malignant peripheral nerve sheath tumor of the cauda equina. ⁶²	Acharya R...Sehgal AD	11731882	2001
15	Primary primitive neuroectodermal tumor of the cauda equina. ⁶²	Isotalo PA...Robertson SJ	10987262	2000
16	Paraganglioma of the cauda equina. A case report and review of the literature. ⁶²	Bak J...Spannare B	8611199	1996
17	Sclerosing fibrous tumor of the cauda equina: a fibroblastic variant of peripheral nerve tumors? ⁶²	Hisaoka M...Rikimaru S	8213075	1993
18	Cauda equina tumor with ependymal and paraganglionic differentiation. ⁶²	Caccamo DV...Garcia JH	1612583	1992
19	[Mobile neurinoma of the cauda equina; a case report]. ⁶²	Satoh T...Date I	1944801	1991
20	Multiple neurilemmoma of the cauda equina. A case report. ⁶²	Shikata J...Shimizu K	1774600	1991
21	Hydrocephalus and cavernoma of the cauda equina. ⁶²	Ramos F...Jan M	2377272	1990
22	[Posterior hernia of the intervertebral disk combined with a tumor of the cauda equina]. ⁶²	Dolzhenko DA...Perfil'ev VM	2816195	1989
23	[Human chorionic gonadotropin-producing tumor of the cauda equina. Case report]. ⁶²	Takenaka N...Takamiya Y	2452369	1987
24	Elusive tumor of the cauda equina. Case report. ⁶²	Tavy DL...Hekster RE	3783245	1987
25	[Hydrocephalus aresorptivus and parkinsonism caused by a cauda ependymoma]. ⁶²	Kalff R	3997033	1985
26	[Papillary stasis caused by tumor of the cauda equina]. ⁶²	Bessiere E...Descamp F	5400737	1969
27	[Coccygodynia revealing a giant tumor of the cauda equina]. ⁶²	Chateau R...Perret J	5619326	1967
28	[Lumbosacral destruction caused by a giant tumor of the cauda equina (apropos of a case of operated ependymoma)]. ⁶²	Courson B...Lemercier G	5865018	1965
29	[Meningeal hemorrhages of spinal origin; diffuse subarachnoid hemorrhage following a tumor of the cauda equina]. ⁶²	FERNANDEZ G...PASEYRO P	13394901	1956
30	[Tumor of the cauda equina with papillary stasis]. ⁶²	JENTZER A...BONNANT M	13056402	1952
31	Gumma simulating tumor of the cauda equina. ⁶²	THOMPSON RG...PRESTON RH	15419389	1950
32	XI. Tumor of the Cauda Equina Removed by Operation: Recovery. ⁶²	Elsworth RC	17862052	1907

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Genes for Cauda Equina Neoplasm

Genes related to Cauda Equina Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ENO2	Enolase 2	Protein Coding	5.24	DISEASES inferred ¹⁴
2	SYP	Synaptophysin	Protein Coding	5.15	DISEASES inferred ¹⁴
3	UCHL1	Ubiquitin C-Terminal Hydrolase L1	Protein Coding	4.88	DISEASES inferred ¹⁴
4	EWSR1	EWS RNA Binding Protein 1	Protein Coding	4.83	DISEASES inferred ¹⁴
5	CHGA	Chromogranin A	Protein Coding	4.54	DISEASES inferred ¹⁴
6	WT1	WT1 Transcription Factor	Protein Coding	4.46	DISEASES inferred ¹⁴
7	RBFOX3	RNA Binding Fox-1 Homolog 3	Protein Coding	3.27	DISEASES inferred ¹⁴

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Variations for Cauda Equina Neoplasm

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Expression for Cauda Equina Neoplasm

Search GEO for disease gene expression data for Cauda Equina Neoplasm.

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Pathways for Cauda Equina Neoplasm

Pathways related to Cauda Equina Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ³	11.46	UCHL1 SYP RBFOX3 ENO2

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GO Terms for Cauda Equina Neoplasm

Cellular components related to Cauda Equina Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	neuron projection terminus	GO:0044306	8.8	UCHL1 SYP

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Sources for Cauda Equina Neoplasm

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MCID: CDQ003 MIFTS: 22	Cauda Equina Neoplasm Categories: Cancer diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
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