MCID: CVR001
MIFTS: 24

Cavernous Sinus Meningioma

Categories: Cancer diseases, Neuronal diseases, Bone diseases

Aliases & Classifications for Cavernous Sinus Meningioma

MalaCards integrated aliases for Cavernous Sinus Meningioma:

Name: Cavernous Sinus Meningioma 12 15 73
Meningioma of the Cavernous Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4435
NCIt 50 C5268
UMLS 73 C1332865

Summaries for Cavernous Sinus Meningioma

MalaCards based summary : Cavernous Sinus Meningioma, also known as meningioma of the cavernous sinus, is related to petroclival meningioma and cavernous sinus thrombosis, and has symptoms including headache and seizures. An important gene associated with Cavernous Sinus Meningioma is NT5C3A (5'-Nucleotidase, Cytosolic IIIA), and among its related pathways/superpathways is Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Cavernous Sinus Meningioma

Diseases related to Cavernous Sinus Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 petroclival meningioma 9.9 CD163 NT5C3A
2 cavernous sinus thrombosis 9.8 GSTO1 NT5C3A
3 thrombosis 9.8
4 exotropia 9.8
5 astrocytoma 9.8
6 grade iii astrocytoma 9.8
7 carotid artery occlusion 9.8
8 ocular neuromyotonia 9.8
9 headache 9.8
10 langerhans cell sarcoma 9.6 CD163 CD207
11 histiocytic and dendritic cell cancer 9.6 CD163 CD207
12 non-langerhans-cell histiocytosis 9.5 CD163 CD207
13 reticulohistiocytic granuloma 9.4 CD163 CD207
14 central nervous system tuberculosis 9.3 CD163 CD207
15 langerhans cell histiocytosis 9.2 CD163 CD207
16 histiocytosis 9.0 CD163 CD207

Graphical network of the top 20 diseases related to Cavernous Sinus Meningioma:



Diseases related to Cavernous Sinus Meningioma

Symptoms & Phenotypes for Cavernous Sinus Meningioma

UMLS symptoms related to Cavernous Sinus Meningioma:


headache, seizures

GenomeRNAi Phenotypes related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

26 (show all 24)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.85 NT5C3A CD207
2 Increased shRNA abundance (Z-score > 2) GR00366-A-116 9.85 CD207
3 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.85 NT5C3A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.85 NT5C3A
5 Increased shRNA abundance (Z-score > 2) GR00366-A-124 9.85 CD163
6 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.85 NT5C3A
7 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.85 CD163
8 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.85 NT5C3A
9 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.85 NT5C3A CD163
10 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.85 NT5C3A
11 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.85 CD207
12 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.85 CD163
13 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.85 CD207
14 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.85 NT5C3A
15 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.85 CD207
16 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.85 NT5C3A
17 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.85 CD163
18 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.85 CD163
19 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.85 CD163
20 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.85 CD163 CD207
21 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.85 NT5C3A
22 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.85 CD163
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-171 9.13 NT5C3A
24 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.13 CD207 NT5C3A

Drugs & Therapeutics for Cavernous Sinus Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Irradiation of the Cavernous Sinus and the Sellar Region on Autobiographical Memory Recruiting NCT02750371 Not Applicable

Search NIH Clinical Center for Cavernous Sinus Meningioma

Genetic Tests for Cavernous Sinus Meningioma

Anatomical Context for Cavernous Sinus Meningioma

MalaCards organs/tissues related to Cavernous Sinus Meningioma:

41
Bone

Publications for Cavernous Sinus Meningioma

Articles related to Cavernous Sinus Meningioma:

(show all 25)
# Title Authors Year
1
Management of Cavernous Sinus Meningioma Presenting With Cerebrovascular Insufficiency Secondary to Cavernous Carotid Artery Occlusion: Report of 2 Cases. ( 29850864 )
2018
2
Endoscopic Endonasal Transmaxillary Transshpenoidal Approach for Excision of a Superior Orbital Fissure-Cavernous Sinus Meningioma: 2-Dimensional Operative Video. ( 29718332 )
2018
3
Cavernous sinus meningioma presenting as third nerve palsy in pregnancy. ( 29754131 )
2018
4
Microsurgical Resection of Cavernous Sinus Meningioma: 2-Dimensional Operative Video. ( 29514273 )
2018
5
The occipital artery as an alternative donor for low-flow bypass to anterior circulation after ICA occlusion failure prior to exenteration for an atypical cavernous sinus meningioma: A technical case report. ( 28887285 )
2017
6
Stereotactic Gamma Knife surgery safety and efficacy in the management of symptomatic benign confined cavernous sinus meningioma. ( 26231629 )
2015
7
Variability in target delineation for cavernous sinus meningioma and anaplastic astrocytoma in stereotactic radiosurgery with Leksell Gamma Knife Perfexion. ( 25246145 )
2014
8
Successful Management of Refractory Headache and Facial Pain due to Cavernous Sinus Meningioma with Sphenopalatine Ganglion Radiofrequency. ( 25343051 )
2014
9
Superior and inferior ophthalmic veins thrombosis with cavernous sinus meningioma. ( 21887086 )
2011
10
Visual outcome after surgery for cavernous sinus meningioma. ( 18421411 )
2008
11
Cavernous sinus meningioma presenting as intermittent exotropia in a 2-year-old girl. ( 17392878 )
2007
12
Pupil sparing incomplete third nerve palsy secondary to a cavernous sinus meningioma: challenges in management. ( 17311575 )
2007
13
Internal carotid occlusion following gamma knife radiosurgery for cavernous sinus meningioma. ( 17709985 )
2007
14
Long-term outcomes of Gamma Knife surgery for cavernous sinus meningioma. ( 17937218 )
2007
15
Ocular neuromyotonia secondary to a cavernous sinus meningioma. ( 16717232 )
2006
16
Decompression of cavernous sinus meningioma for preservation and improvement of cranial nerve function. Technical note. ( 16871891 )
2006
17
Gaze-evoked amaurosis with cavernous sinus meningioma. ( 15999132 )
2006
18
Fractionated stereotactic radiotherapy in the treatment of exclusive cavernous sinus meningioma: functional outcome, local control, and tolerance. ( 16378847 )
2006
19
Abnormal flash but normal pattern VEP in a cavernous sinus meningioma. ( 14661911 )
2003
20
Cavernous sinus meningioma. ( 11883858 )
2002
21
Iatrogenic carotid-cavernous fistula occurring after embolization of a cavernous sinus meningioma. ( 7793369 )
1995
22
Cavernous sinus meningioma presenting as orbital apex syndrome. Diagnostic methods of dynamic MRI, spoiled GRASS (SPGR) image. ( 8927246 )
1995
23
Infiltration of the carotid artery by cavernous sinus meningioma. ( 8027809 )
1994
24
Agenesis of the internal carotid artery and cavernous sinus hypoplasia with contralateral cavernous sinus meningioma. ( 8278037 )
1993
25
Isolated trochlear nerve palsy secondary to cavernous sinus meningioma. ( 3661659 )
1987

Variations for Cavernous Sinus Meningioma

Expression for Cavernous Sinus Meningioma

Search GEO for disease gene expression data for Cavernous Sinus Meningioma.

Pathways for Cavernous Sinus Meningioma

Pathways related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.49 CD163 CD207

GO Terms for Cavernous Sinus Meningioma

Biological processes related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor-mediated endocytosis GO:0006898 8.96 CD163 CD207
2 defense response to virus GO:0051607 8.62 CD207 NT5C3A

Sources for Cavernous Sinus Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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