MCID: CVR001
MIFTS: 31

Cavernous Sinus Meningioma

Categories: Bone diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Cavernous Sinus Meningioma

MalaCards integrated aliases for Cavernous Sinus Meningioma:

Name: Cavernous Sinus Meningioma 12 15 74
Meningioma of the Cavernous Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4435
NCIt 51 C5268
UMLS 74 C1332865

Summaries for Cavernous Sinus Meningioma

MalaCards based summary : Cavernous Sinus Meningioma, also known as meningioma of the cavernous sinus, is related to meningioma, familial and spinal meningioma, and has symptoms including seizures and headache. An important gene associated with Cavernous Sinus Meningioma is NT5C3A (5'-Nucleotidase, Cytosolic IIIA), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Tight junction. Affiliated tissues include bone and thymus, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Cavernous Sinus Meningioma

Graphical network of the top 20 diseases related to Cavernous Sinus Meningioma:



Diseases related to Cavernous Sinus Meningioma

Symptoms & Phenotypes for Cavernous Sinus Meningioma

UMLS symptoms related to Cavernous Sinus Meningioma:


seizures, headache

GenomeRNAi Phenotypes related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

27 (show all 21)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.7 NT5C3A
2 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.7 NT5C3A
3 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.7 NT5C3A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-124 9.7 CD163
5 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.7 NT5C3A
6 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.7 CD163
7 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.7 NT5C3A
8 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.7 CD163 NF1 NT5C3A
9 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.7 NT5C3A
10 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.7 CD163
11 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.7 NT5C3A
12 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.7 NF1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.7 NT5C3A
14 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.7 CD163
15 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.7 NT5C3A
16 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.7 CD163 NF1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.7 CD163
18 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.7 CD163
19 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.7 NT5C3A
20 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.7 CD163
21 Increased shRNA abundance (Z-score > 2) GR00366-A-97 9.7 NF1

Drugs & Therapeutics for Cavernous Sinus Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Irradiation of the Cavernous Sinus and the Sellar Region on Autobiographical Memory Recruiting NCT02750371 Not Applicable

Search NIH Clinical Center for Cavernous Sinus Meningioma

Genetic Tests for Cavernous Sinus Meningioma

Anatomical Context for Cavernous Sinus Meningioma

MalaCards organs/tissues related to Cavernous Sinus Meningioma:

42
Bone, Thymus

Publications for Cavernous Sinus Meningioma

Articles related to Cavernous Sinus Meningioma:

(show all 29)
# Title Authors Year
1
Management of Cavernous Sinus Meningioma Presenting With Cerebrovascular Insufficiency Secondary to Cavernous Carotid Artery Occlusion: Report of 2 Cases. ( 29850864 )
2019
2
The Occipital Artery as an Alternative Donor for Low-Flow Bypass to Anterior Circulation After Internal Carotid Artery Occlusion Failure prior to Exenteration for an Atypical Cavernous Sinus Meningioma. ( 28887285 )
2018
3
Microsurgical Resection of Cavernous Sinus Meningioma: 2-Dimensional Operative Video. ( 29514273 )
2018
4
Endoscopic Endonasal Transmaxillary Transsphenoidal Approach for Excision of a Superior Orbital Fissure-Cavernous Sinus Meningioma: 2-Dimensional Operative Video. ( 29718332 )
2018
5
Cavernous sinus meningioma presenting as third nerve palsy in pregnancy. ( 29754131 )
2018
6
Gamma Knife stereotactic radiosurgery for cavernous sinus meningioma: long-term follow-up in 200 patients. ( 30028261 )
2018
7
Radiosurgery and fractionated radiotherapy for cavernous sinus meningioma: a systematic review and meta-analysis. ( 30393820 )
2018
8
Stereotactic Gamma Knife surgery safety and efficacy in the management of symptomatic benign confined cavernous sinus meningioma. ( 26231629 )
2015
9
Variability in target delineation for cavernous sinus meningioma and anaplastic astrocytoma in stereotactic radiosurgery with Leksell Gamma Knife Perfexion. ( 25246145 )
2014
10
Successful Management of Refractory Headache and Facial Pain due to Cavernous Sinus Meningioma with Sphenopalatine Ganglion Radiofrequency. ( 25343051 )
2014
11
Superior and inferior ophthalmic veins thrombosis with cavernous sinus meningioma. ( 21887086 )
2011
12
Meningioma of the cavernous sinus in a child: case report and review of the literature. ( 19642507 )
2009
13
Visual outcome after surgery for cavernous sinus meningioma. ( 18421411 )
2008
14
Pupil sparing incomplete third nerve palsy secondary to a cavernous sinus meningioma: challenges in management. ( 17311575 )
2007
15
Cavernous sinus meningioma presenting as intermittent exotropia in a 2-year-old girl. ( 17392878 )
2007
16
Internal carotid occlusion following gamma knife radiosurgery for cavernous sinus meningioma. ( 17709985 )
2007
17
Long-term outcomes of Gamma Knife surgery for cavernous sinus meningioma. ( 17937218 )
2007
18
Gaze-evoked amaurosis with cavernous sinus meningioma. ( 15999132 )
2006
19
Fractionated stereotactic radiotherapy in the treatment of exclusive cavernous sinus meningioma: functional outcome, local control, and tolerance. ( 16378847 )
2006
20
Ocular neuromyotonia secondary to a cavernous sinus meningioma. ( 16717232 )
2006
21
Decompression of cavernous sinus meningioma for preservation and improvement of cranial nerve function. Technical note. ( 16871891 )
2006
22
Abnormal flash but normal pattern VEP in a cavernous sinus meningioma. ( 14661911 )
2003
23
Cavernous sinus meningioma. ( 11883858 )
2002
24
Meningioma of the cavernous sinus in a child. ( 10066014 )
1999
25
Iatrogenic carotid-cavernous fistula occurring after embolization of a cavernous sinus meningioma. ( 7793369 )
1995
26
Cavernous sinus meningioma presenting as orbital apex syndrome. Diagnostic methods of dynamic MRI, spoiled GRASS (SPGR) image. ( 8927246 )
1995
27
Infiltration of the carotid artery by cavernous sinus meningioma. ( 8027809 )
1994
28
Agenesis of the internal carotid artery and cavernous sinus hypoplasia with contralateral cavernous sinus meningioma. ( 8278037 )
1993
29
Isolated trochlear nerve palsy secondary to cavernous sinus meningioma. ( 3661659 )
1987

Variations for Cavernous Sinus Meningioma

Expression for Cavernous Sinus Meningioma

Search GEO for disease gene expression data for Cavernous Sinus Meningioma.

Pathways for Cavernous Sinus Meningioma

GO Terms for Cavernous Sinus Meningioma

Cellular components related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.97 CD163 CD1A CD1B CD1C CD1D CD1E
2 integral component of plasma membrane GO:0005887 9.72 CD163 CD1A CD1C CD1D CD1E
3 lysosome GO:0005764 9.56 CD1B CD1C CD1D CD1E
4 endosome GO:0005768 9.35 CD1A CD1B CD1C CD1D CD1E
5 cell surface GO:0009986 9.16 CD1B CD1D
6 endosome membrane GO:0010008 8.92 CD1A CD1B CD1C CD1D

Biological processes related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.77 CD1A CD1B CD1C CD1D CD1E
2 adaptive immune response GO:0002250 9.71 CD1A CD1B CD1C CD1E
3 immune response GO:0006955 9.65 CD1A CD1B CD1C CD1D CD1E
4 regulation of immune response GO:0050776 9.62 CD1A CD1B CD1C CD1D
5 positive regulation of T cell mediated cytotoxicity GO:0001916 9.55 CD1A CD1B CD1C CD1D CD1E
6 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.35 CD1A CD1B CD1C CD1D CD1E
7 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 9.02 CD1A CD1B CD1C CD1D CD1E

Molecular functions related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopeptide binding GO:0071723 9.55 CD1A CD1B CD1C CD1D CD1E
2 lipid binding GO:0008289 9.43 CD1C CD1E NF1
3 endogenous lipid antigen binding GO:0030883 9.35 CD1A CD1B CD1C CD1D CD1E
4 exogenous lipid antigen binding GO:0030884 9.02 CD1A CD1B CD1C CD1D CD1E

Sources for Cavernous Sinus Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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