MCID: CVR001
MIFTS: 26

Cavernous Sinus Meningioma

Categories: Bone diseases, Cancer diseases, Neuronal diseases
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Aliases & Classifications for Cavernous Sinus Meningioma

MalaCards integrated aliases for Cavernous Sinus Meningioma:

Name: Cavernous Sinus Meningioma 11 5 14 71
Meningioma of the Cavernous Sinus 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4435
NCIt 49 C5268
UMLS 71 C1332865

Summaries for Cavernous Sinus Meningioma

MalaCards based summary: Cavernous Sinus Meningioma, also known as meningioma of the cavernous sinus, is related to meningioma, familial and chordoid meningioma, and has symptoms including headache and seizures. An important gene associated with Cavernous Sinus Meningioma is KMT2D (Lysine Methyltransferase 2D). Affiliated tissues include bone, brain and pituitary, and related phenotype is neoplasm.

Related Diseases for Cavernous Sinus Meningioma

Diseases related to Cavernous Sinus Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 80)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 30.4 TRAF7 SMARCE1 POLR2A NF2
2 chordoid meningioma 30.2 TRAF7 NF2
3 psammomatous meningioma 29.8 TRAF7 POLR2A NF2
4 skull base meningioma 29.6 TRAF7 SMARCE1 POLR2A NF2
5 sphenoorbital meningioma 29.4 TRAF7 SMARCE1 RGPD3 NF2
6 fibrous meningioma 29.2 TRAF7 SMARCE1 POLR2A NF2
7 ptosis 10.4
8 papillon-lefevre syndrome 10.3
9 carotid artery occlusion 10.3
10 kearns-sayre syndrome 10.3
11 cranial nerve palsy 10.3
12 aphasia 10.2
13 carotid stenosis 10.2
14 headache 10.2
15 hemifacial hyperplasia 10.1
16 central nervous system cancer 10.1
17 abducens palsy 10.0
18 glioma susceptibility 1 10.0
19 strabismus 10.0
20 trigeminal neuralgia 10.0
21 pituitary adenoma 4, acth-secreting 10.0
22 neurodegeneration with brain iron accumulation 2a 10.0
23 paine syndrome 10.0
24 meningioma, radiation-induced 10.0
25 thrombosis 10.0
26 fourth cranial nerve palsy 10.0
27 arteriovenous malformation 10.0
28 exotropia 10.0
29 conn's syndrome 10.0
30 facial neuralgia 10.0
31 optic nerve disease 10.0
32 hemangioma 10.0
33 anaplastic astrocytoma 10.0
34 neurilemmoma 10.0
35 plasmacytoma 10.0
36 pituitary-dependent cushing's disease 10.0
37 pituitary gland disease 10.0
38 childhood leukemia 10.0
39 episodic ataxia 10.0
40 cluster headache 10.0
41 internal carotid agenesis 10.0
42 ocular neuromyotonia 10.0
43 posttransplant acute limbic encephalitis 10.0
44 specific language disorder 10.0
45 cranial neuralgia 10.0
46 tuberculum sellae meningioma 10.0 TRAF7 NF2
47 sella turcica neoplasm 10.0 TRAF7 NF2
48 optic nerve sheath meningioma 10.0 TRAF7 NF2
49 intraneural perineurioma 10.0 TRAF7 NF2
50 cerebellopontine angle tumor 9.9 RGPD3 NF2

Graphical network of the top 20 diseases related to Cavernous Sinus Meningioma:



Diseases related to Cavernous Sinus Meningioma

Symptoms & Phenotypes for Cavernous Sinus Meningioma

UMLS symptoms related to Cavernous Sinus Meningioma:


headache; seizures

MGI Mouse Phenotypes related to Cavernous Sinus Meningioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 KMT2D NF2 POLR2A RGPD3

Drugs & Therapeutics for Cavernous Sinus Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Irradiation of the Cavernous Sinus and the Sellar Region on Autobiographical Memory Active, not recruiting NCT02750371

Search NIH Clinical Center for Cavernous Sinus Meningioma

Genetic Tests for Cavernous Sinus Meningioma

Anatomical Context for Cavernous Sinus Meningioma

Organs/tissues related to Cavernous Sinus Meningioma:

MalaCards : Bone, Brain, Pituitary

Publications for Cavernous Sinus Meningioma

Articles related to Cavernous Sinus Meningioma:

(show top 50) (show all 106)
# Title Authors PMID Year
1
Oculomotor nerve palsy in neurofibromatosis type 2. 62
36120518 2022
2
Does Endoscopic Transnasal Optic Nerve Decompression Followed by Radiosurgery Improve Outcomes in the Treatment of Parasellar Meningiomas? 62
36013604 2022
3
Combined Transcavernous and Kawase's Approach for Gross Total Resection of a Cavernous Sinus Meningioma. 62
36068902 2022
4
Gross Total Resection of a Recurrent in-and-around Cavernous Sinus Meningioma through a Combined Transcavernous Anterior and Middle Infratemporal Fossa Approach with Extracranial-Intracranial Bypass. 62
36068904 2022
5
Gross Total Resection of a Recurrent Cavernous Sinus Meningioma through a Combined Transzygomatic Transcavernous and Extended Middle Fossa Approach with Cavernous Carotid Denudation. 62
36068891 2022
6
A case series of percutaneous transforamen ovale biopsies in cavernous sinus lesions. 62
34136959 2022
7
Isolated incomplete third cranial nerve palsy due to presumed cavernous sinus meningioma. 62
35388256 2022
8
Cavernous Sinus Meningioma: Tumor Decompression for Trigeminal Neuralgia and Anterior Tibial Artery Graft High-Flow Bypass for Brain Ischemia: 2-Dimensional Operative Video. 62
34164683 2021
9
Aggressive Radiation-Induced Cavernous Sinus Meningioma: 2-Dimensional Operative Video. 62
34133742 2021
10
Coexistent vestibular schwannoma and meningioma in a patient without neurofibromatosis: A case report and review of literature. 62
34540986 2021
11
STA-MCA Bypass in Carotid Stenosis after Radiosurgery for Cavernous Sinus Meningioma. 62
34067741 2021
12
Single- and Multi-Fraction Stereotactic Radiosurgery Dose Tolerances of the Optic Pathways. 62
29534899 2021
13
Management Strategy for a Patient with Coexistence of Meningioma and Paraophthalmic Aneurysm. 62
34027874 2021
14
Postpartum Recovery From Meningioma-Related Oculomotor Palsy. 62
33706360 2021
15
Cavernous Sinus Meningioma Resection Through Orbitozygomatic Craniotomy. 62
33515796 2021
16
Intracranial Plasmacytoma Mimicking a Cavernous Sinus Meningioma. 62
33614321 2021
17
Multimodal therapy of cavernous sinus meningioma: Impact of surgery and 68Ga-DOTATATE PET-guided radiation therapy on tumor control and functional outcome. 62
34704034 2021
18
Radiation-induced cavernous malformation after stereotactic radiosurgery for cavernous sinus meningioma: a case report. 62
33218314 2020
19
Intracranial soft-tissue glomus tumor (glomangioma) in a young-woman. A case report and review of the literature. 62
33295301 2020
20
Phantosmia as the first presentation of a cavernous sinus - clinoidal meningioma. 62
33050720 2020
21
Resection of Invasive Sphenoorbital and Cavernous Sinus Meningioma via Frontotemporal Craniotomy. 62
32416238 2020
22
Cavernous Sinus Meningioma with Orbital Involvement: Algorithmic Decision-Making and Treatment Strategy. 62
33072476 2020
23
Predictors of visual functional outcome following treatment for cavernous sinus meningioma. 62
32413851 2020
24
Resection of Cavernous Sinus Meningioma via Lateral Orbitotomy Approach: 2-Dimensional Operative Video. 62
31301136 2020
25
Commentary: Resection of Cavernous Sinus Meningioma via Lateral Orbitotomy Approach: 2-Dimensional Operative Video. 62
31313818 2020
26
Inter-Observer Variability in Target Volume Delineations of Benign and Metastatic Brain Tumours for Stereotactic Radiosurgery: Results of a National Quality Assurance Programme. 62
31301960 2020
27
Cavernous sinus meningioma. 62
32586510 2020
28
Risk of internal carotid artery stenosis or occlusion after single-fraction radiosurgery for benign parasellar tumors. 62
31653808 2019
29
Immunological and vascular characteristics in cavernous sinus meningioma. 62
31213381 2019
30
Nonsecretory Paraganglioma in Cavernous Sinus Masquerading as Meningioma. 62
30831293 2019
31
Management of Cavernous Sinus Meningioma Presenting With Cerebrovascular Insufficiency Secondary to Cavernous Carotid Artery Occlusion: Report of 2 Cases. 62
29850864 2019
32
[Progress in the treatment of cavernous sinus meningioma]. 62
30929379 2019
33
Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association? 62
30726411 2019
34
Evidence-based treatment of cavernous sinus meningioma. 62
31819821 2019
35
Microsurgical Resection of Cavernous Sinus Meningioma: 2-Dimensional Operative Video. 62
29514273 2018
36
Radiosurgery and fractionated radiotherapy for cavernous sinus meningioma: a systematic review and meta-analysis. 62
30393820 2018
37
Endoscopic Endonasal Transmaxillary Transsphenoidal Approach for Excision of a Superior Orbital Fissure-Cavernous Sinus Meningioma: 2-Dimensional Operative Video. 62
29718332 2018
38
Multi-institutional study of the variability in target delineation for six targets commonly treated with radiosurgery. 62
29786462 2018
39
Cranial nerve outcomes after primary stereotactic radiosurgery for symptomatic skull base meningiomas. 62
29691775 2018
40
Gamma Knife stereotactic radiosurgery for cavernous sinus meningioma: long-term follow-up in 200 patients. 62
30028261 2018
41
Cavernous sinus meningioma presenting as third nerve palsy in pregnancy. 62
29754131 2018
42
The Occipital Artery as an Alternative Donor for Low-Flow Bypass to Anterior Circulation After Internal Carotid Artery Occlusion Failure prior to Exenteration for an Atypical Cavernous Sinus Meningioma. 62
28887285 2018
43
Optic disc drusen: longitudinal aspects, with emphasis on visual field constriction and enlarged blind spot: a retrospective hospital-based clinical series. 62
27646322 2017
44
Gamma Knife Radiosurgery for Cavernous Sinus Meningiomas: Analysis of Outcome in 166 Patients. 62
28797005 2017
45
Assessment of organs-at-risk contouring practices in radiosurgery institutions around the world - The first initiative of the OAR Standardization Working Group. 62
27816408 2016
46
Outcomes after surgical treatment of meningioma-associated proptosis. 62
26799293 2016
47
Postpartum Regression of a Presumed Cavernous Meningioma. 62
27066285 2016
48
Stereotactic Gamma Knife surgery safety and efficacy in the management of symptomatic benign confined cavernous sinus meningioma. 62
26231629 2015
49
[Secondary cluster headache due to cavernous sinus meningioma]. 62
25944140 2015
50
Urgent cerebral revascularization bypass surgery for iatrogenic skull base internal carotid artery injury. 62
25181433 2014

Variations for Cavernous Sinus Meningioma

ClinVar genetic disease variations for Cavernous Sinus Meningioma:

5
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 KMT2D NM_003482.4(KMT2D):c.11047C>T (p.Gln3683Ter) SNV Likely Pathogenic
635179 rs1565779530 GRCh37: 12:49427441-49427441
GRCh38: 12:49033658-49033658
2 DHFR, MSH3 NM_000791.4(DHFR):c.-416C>G SNV Uncertain Significance
635180 rs2001675 GRCh37: 5:79950724-79950724
GRCh38: 5:80654905-80654905

Expression for Cavernous Sinus Meningioma

Search GEO for disease gene expression data for Cavernous Sinus Meningioma.

Pathways for Cavernous Sinus Meningioma

GO Terms for Cavernous Sinus Meningioma

Biological processes related to Cavernous Sinus Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell differentiation GO:0045597 8.92 SMARCE1 NF2

Sources for Cavernous Sinus Meningioma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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