MCID: CD3001
MIFTS: 13

Cd3zeta Deficiency

Categories: Immune diseases

Aliases & Classifications for Cd3zeta Deficiency

MalaCards integrated aliases for Cd3zeta Deficiency:

Name: Cd3zeta Deficiency 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060007

Summaries for Cd3zeta Deficiency

Disease Ontology : 12 A severe combined immunodeficiency that affects the development and function of T cells.

MalaCards based summary : Cd3zeta Deficiency is related to rhinoscleroma and colon carcinoma in situ. An important gene associated with Cd3zeta Deficiency is CD247 (CD247 Molecule), and among its related pathways/superpathways are Adhesion and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include t cells.

Related Diseases for Cd3zeta Deficiency

Diseases related to Cd3zeta Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 rhinoscleroma 9.6 CCR2 NCAM1
2 colon carcinoma in situ 9.1 CD44 NCAM1
3 myeloma, multiple 8.9 CD44 NCAM1

Symptoms & Phenotypes for Cd3zeta Deficiency

Drugs & Therapeutics for Cd3zeta Deficiency

Search Clinical Trials , NIH Clinical Center for Cd3zeta Deficiency

Genetic Tests for Cd3zeta Deficiency

Anatomical Context for Cd3zeta Deficiency

MalaCards organs/tissues related to Cd3zeta Deficiency:

41
T Cells

Publications for Cd3zeta Deficiency

Variations for Cd3zeta Deficiency

Expression for Cd3zeta Deficiency

Search GEO for disease gene expression data for Cd3zeta Deficiency.

Pathways for Cd3zeta Deficiency

GO Terms for Cd3zeta Deficiency

Biological processes related to Cd3zeta Deficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interferon-gamma-mediated signaling pathway GO:0060333 8.96 CD44 NCAM1
2 viral process GO:0016032 8.8 CCR2 CD247 NCAM1

Sources for Cd3zeta Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....