Aliases & Classifications for Cd4/cd8 T-Cell Ratio

MalaCards integrated aliases for Cd4/cd8 T-Cell Ratio:

Name: Cd4/cd8 T-Cell Ratio 57

External Ids:

OMIM® 57 601083

Summaries for Cd4/cd8 T-Cell Ratio

MalaCards based summary : Cd4/cd8 T-Cell Ratio is related to peritonitis and multiple sclerosis. An important gene associated with Cd4/cd8 T-Cell Ratio is IFNL1 (Interferon Lambda 1), and among its related pathways/superpathways is Cytokine Signaling in Immune system. Affiliated tissues include t cells, lung and lymph node.

More information from OMIM: 601083

Related Diseases for Cd4/cd8 T-Cell Ratio

Graphical network of the top 20 diseases related to Cd4/cd8 T-Cell Ratio:



Diseases related to Cd4/cd8 T-Cell Ratio

Symptoms & Phenotypes for Cd4/cd8 T-Cell Ratio

Clinical features from OMIM®:

601083 (Updated 05-Apr-2021)

Drugs & Therapeutics for Cd4/cd8 T-Cell Ratio

Search Clinical Trials , NIH Clinical Center for Cd4/cd8 T-Cell Ratio

Genetic Tests for Cd4/cd8 T-Cell Ratio

Anatomical Context for Cd4/cd8 T-Cell Ratio

MalaCards organs/tissues related to Cd4/cd8 T-Cell Ratio:

40
T Cells, Lung, Lymph Node, Bone, Bone Marrow, Heart, Skin

Publications for Cd4/cd8 T-Cell Ratio

Articles related to Cd4/cd8 T-Cell Ratio:

(show top 50) (show all 319)
# Title Authors PMID Year
1
Genetic control of the CD4/CD8 T-cell ratio in humans. 57 61
7489409 1995
2
CD4 and CD8 T lymphocyte inheritance. Evidence for major autosomal recessive genes. 57
10543402 1999
3
The CD4/CD8 ratio: message in a bottle? 57
7489396 1995
4
Genetic control of T-cell subset representation in inbred mice. 57
6606619 1983
5
Corrigendum to "Inverted CD4 +/CD8+T cell ratio in Boran (Bos indicus) cattle" [Vet. Immunol. Immunopathol. 230 110126]. 61
33743998 2021
6
Clinically isolated descending thoracic aortitis in a healthy older woman: a diagnostic challenge. 61
33602759 2021
7
Circulating immune parameters-based nomogram for predicting malignancy in laryngeal neoplasm. 61
33553392 2021
8
Disruption of CCR5 signaling to treat COVID-19-associated cytokine storm: Case series of four critically ill patients treated with leronlimab. 61
33521616 2021
9
Implications of perioperative allogeneic red blood cell transfusion on the immune-inflammatory response. 61
32532624 2021
10
Inverted CD4+/CD8+ T cell ratio in Boran (Bos indicus) cattle. 61
33080530 2020
11
Sex as a confounding factor in the effects of ageing on rat lymph node t cell compartment. 61
33129930 2020
12
CD4+:CD8+ T Cell Ratio Normalization and the Development of AIDS Events in People with HIV Starting Antiretroviral Therapy. 61
32664736 2020
13
The role of cytokine profile and lymphocyte subsets in the severity of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis. 61
32735885 2020
14
Ma-Nuo-Xi decoction has an immunostimulating effect in cyclophosphamide-immunosuppressed mice. 61
32954763 2020
15
Characteristics of suboptimal immune response after initiating antiretroviral therapy among people living with HIV with a pre-treatment CD4 T cell count <200 ​cells/mm3 in Thailand. 61
33251023 2020
16
Systemic sarcoidosis revealed by venepunctures: a very rare but rewarding cutaneous manifestation. 61
32900730 2020
17
CD4+/CD8+ T-Cell Ratio Predictive of Surgical Margins in the Treatment of Nonmelanoma Skin Cancer Treated With Mohs Surgery of Patients Infected With the Human Immunodeficiency Virus. 61
32897950 2020
18
Association of a Type 2-Polarized T Cell Phenotype With Methotrexate Nonresponse in Patients With Rheumatoid Arthritis. 61
32039570 2020
19
Molecular Mechanisms of Premature Aging in Hemodialysis: The Complex Interplay Between Innate and Adaptive Immune Dysfunction. 61
32408613 2020
20
Combined Black Rice Germ, Bran Supplement and Exercise Intervention Modulate Aging Biomarkers and Improve Physical Performance and Lower-Body Muscle Strength Parameters in Aging Population. 61
32340343 2020
21
Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection. 61
32295609 2020
22
Immune Biomarkers in the Prediction of Future Myocardial Infarctions in People With Human Immunodeficiency Virus. 61
31414117 2020
23
CD4+ /CD8+ T-cell ratio correlates with the graft fate in pig-to-non-human primate islet xenotransplantation. 61
31642566 2020
24
CD4+:CD8+ T-cell ratio changes in people with HIV receiving antiretroviral treatment. 61
32338638 2020
25
Impact of ART on dynamics of growth factors and cytokines in primary HIV infection. 61
31542514 2020
26
Depletion and activation of mucosal CD4 T cells in HIV infected women with HPV-associated lesions of the cervix uteri. 61
33007050 2020
27
Low CSF CD4/CD8+ T-cell proportions are associated with blood-CSF barrier dysfunction in limbic encephalitis. 61
31846897 2020
28
Absence of peripapillary retinal nerve-fiber-layer thinning in combined antiretroviral therapy-treated, well-sustained aviremic persons living with HIV. 61
32155200 2020
29
PPARγ Deficiency in Carbon Nanotube-elicited Granulomatous Inflammation Promotes a Th17 Response to a Microbial Antigen. 61
32405439 2020
30
Elucidation of Cellular Responses in Non-human Primates With Chronic Schistosomiasis Followed by Praziquantel Treatment. 61
32154190 2020
31
Mycobacterium bovis Bacille-Calmette-Guérin Infection Aggravates Atherosclerosis. 61
33391278 2020
32
Effect of low dose naloxone on the immune system function of a patient undergoing video-assisted thoracoscopic resection of lung cancer with sufentanil controlled analgesia - a randomized controlled trial. 61
31856760 2019
33
CD4/CD8 + T cells, DC subsets, Foxp3, and IDO expression are predictive indictors of gastric cancer prognosis. 61
31631566 2019
34
Early T Cell Differentiation with Well-Maintained Function across the Adult Life Course in Sub-Saharan Africa. 61
31358657 2019
35
NK cells in treated HIV-infected children display altered phenotype and function. 61
30735686 2019
36
The evaluation of cellular immune function in elderly patients with systemic lupus erythematosus. 61
29172398 2019
37
Immunologic Features of Patients With Advanced Hepatocellular Carcinoma Before and During Sorafenib or Anti-programmed Death-1/Programmed Death-L1 Treatment. 61
31295151 2019
38
Chronic arsenic exposure in drinking water interferes with the balances of T lymphocyte subpopulations as well as stimulates the functions of dendritic cells in vivo. 61
30889423 2019
39
Incomplete ART adherence is associated with higher inflammation in individuals who achieved virologic suppression in the START study. 61
31250552 2019
40
Immunological recovery in T-cell activation after sustained virologic response among HIV positive and HIV negative chronic Hepatitis C patients. 61
30835046 2019
41
Effect of Lactobacillus plantarum IS-10506 on blood lipopolysaccharide level and immune response in HIV-infected children. 61
31341568 2019
42
B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma. 61
30896447 2019
43
TCR repertoire intratumor heterogeneity of CD4+ and CD8+ T cells in centers and margins of localized lung adenocarcinomas. 61
30151844 2019
44
CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. 61
30686790 2019
45
Naïve/Effector CD4 T cell ratio as a useful predictive marker of immune reconstitution in late presenter HIV patients: A multicenter study. 61
31869342 2019
46
Retrospective Study of Factors Potentially Influencing Occurrence of Cough in Slovak Patients with Sarcoidosis. 61
31281552 2019
47
Cytomegalovirus aggravates the autoimmune phenomenon in systemic autoimmune diseases. 61
29704668 2018
48
Effect of low-dose cyclophosphamide, ACTH, and IVIG combination immunotherapy on neuroinflammation in pediatric-onset OMS: A retrospective pilot study. 61
29555260 2018
49
Reversal of T Cell Exhaustion by the First Donor Lymphocyte Infusion Is Associated with the Persistently Effective Antileukemic Responses in Patients with Relapsed AML after Allo-HSCT. 61
29649617 2018
50
T cells establish and maintain CNS viral infection in HIV-infected humanized mice. 61
29863499 2018

Variations for Cd4/cd8 T-Cell Ratio

Expression for Cd4/cd8 T-Cell Ratio

Search GEO for disease gene expression data for Cd4/cd8 T-Cell Ratio.

Pathways for Cd4/cd8 T-Cell Ratio

Pathways related to Cd4/cd8 T-Cell Ratio according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.73 IL16 IFNL1

GO Terms for Cd4/cd8 T-Cell Ratio

Biological processes related to Cd4/cd8 T-Cell Ratio according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 8.62 IL16 IFNL1

Molecular functions related to Cd4/cd8 T-Cell Ratio according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.62 IL16 IFNL1

Sources for Cd4/cd8 T-Cell Ratio

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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