MCID: CCM004
MIFTS: 27

Cecum Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Cecum Carcinoma

MalaCards integrated aliases for Cecum Carcinoma:

Name: Cecum Carcinoma 12 15 17
Cecum Cancer 12 15
Malignant Neoplasm of Caecum 12
Malignant Tumor of the Cecum 12
Carcinoma of Cecum 12
Caecum Carcinoma 12
Cecal Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1519 DOID:1521
ICD9CM 36 153.4
MeSH 45 D002430
NCIt 51 C3491 C9329
SNOMED-CT 69 93736007
ICD10 34 C18.0

Summaries for Cecum Carcinoma

Disease Ontology : 12 A cecum cancer that has material basis in abnormally proliferating cells derives from epithelial cells.

MalaCards based summary : Cecum Carcinoma, also known as cecum cancer, is related to cecum adenocarcinoma and cecal benign neoplasm. An important gene associated with Cecum Carcinoma is HMX2 (H6 Family Homeobox 2). Affiliated tissues include lymph node and breast, and related phenotype is Increased viability with MLN4924 (a NAE inhibitor).

Related Diseases for Cecum Carcinoma

Diseases related to Cecum Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 cecum adenocarcinoma 31.2 HMX2 KRT7 MSH2 SMUG1
2 cecal benign neoplasm 31.0 HMX2 KRT7 RAB11B SMUG1
3 ascending colon cancer 10.1 MSH2 SMUG1
4 descending colon cancer 10.1 MSH2 SMUG1
5 malignant spiradenoma 10.1 KRT7 SMUG1
6 gallbladder small cell carcinoma 10.1 KRT7 SMUG1
7 jejunal adenocarcinoma 10.1 KRT7 SMUG1
8 eccrine adenocarcinoma 10.1 KRT7 SMUG1
9 prostate squamous cell carcinoma 10.1 KRT7 SMUG1
10 small intestine cancer 10.0 KRT7 MSH2
11 pericardium cancer 10.0 KRT7 SMUG1
12 anus cancer 10.0 KRT7 SMUG1
13 pericardial mesothelioma 10.0 KRT7 SMUG1
14 uterine anomalies 10.0 MSH2 SMUG1
15 oropharynx cancer 10.0 KRT7 SMUG1
16 gastric diffuse adenocarcinoma 10.0 KRT7 RAB11B
17 rectum adenocarcinoma 10.0 KRT7 RAB11B
18 colorectal adenocarcinoma 10.0 KRT7 MSH2
19 female reproductive system disease 10.0 MSH2 SMUG1
20 thymus cancer 10.0 KRT7 SMUG1
21 attenuated familial adenomatous polyposis 9.9 MSH2 MUTYH
22 familial adenomatous polyposis 9.9 MSH2 MUTYH
23 renal cell carcinoma, papillary, 1 9.9 KRT7 MSH2
24 jejunal cancer 9.9 KRT7 MUTYH
25 intestinal benign neoplasm 9.9 MSH2 MUTYH
26 muir-torre syndrome 9.9 MSH2 MUTYH
27 duodenum cancer 9.9 KRT7 MUTYH
28 familial colorectal cancer 9.9 MSH2 MUTYH
29 colorectal adenoma 9.8 MSH2 MUTYH
30 intussusception 9.8
31 inguinal hernia 9.8
32 transitional cell carcinoma 9.8 KRT7 MSH2
33 gas gangrene 9.8
34 paraganglioma 9.8
35 appendicitis 9.8
36 thrombasthenia 9.8
37 cell type benign neoplasm 9.8 KRT7 MUTYH
38 autosomal genetic disease 9.8 MSH2 MUTYH
39 lynch syndrome 9.7 MSH2 MUTYH
40 gastrointestinal system disease 9.7 MSH2 SMUG1
41 intestinal disease 9.6 MSH2 MUTYH SMUG1
42 endometrial cancer 9.4 KRT7 MSH2 MUTYH
43 gastrointestinal system cancer 9.3 KRT7 MSH2 MUTYH SMUG1
44 large intestine cancer 9.0 KRT7 MSH2 MUTYH RAB11B SMUG1

Graphical network of the top 20 diseases related to Cecum Carcinoma:



Diseases related to Cecum Carcinoma

Symptoms & Phenotypes for Cecum Carcinoma

GenomeRNAi Phenotypes related to Cecum Carcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-3 8.8 MSH2 MUTYH SMUG1

Drugs & Therapeutics for Cecum Carcinoma

Search Clinical Trials , NIH Clinical Center for Cecum Carcinoma

Genetic Tests for Cecum Carcinoma

Anatomical Context for Cecum Carcinoma

MalaCards organs/tissues related to Cecum Carcinoma:

42
Lymph Node, Breast

Publications for Cecum Carcinoma

Articles related to Cecum Carcinoma:

# Title Authors Year
1
Metastasis to the penis from cecum carcinoma. ( 19769661 )
2009
2
Isolated right external iliac lymph node recurrence from a primary cecum carcinoma: report of a case. ( 17472973 )
2007
3
Abscess and cecum carcinoma in inguinal hernia: case report. ( 17062196 )
2006
4
Metastasis to the breast from cecum carcinoma. Case report and review of the literature. ( 11789750 )
2001
5
Penile metastasis secondary to cecum carcinoma: a case report. ( 9840111 )
1998

Variations for Cecum Carcinoma

Expression for Cecum Carcinoma

Search GEO for disease gene expression data for Cecum Carcinoma.

Pathways for Cecum Carcinoma

GO Terms for Cecum Carcinoma

Biological processes related to Cecum Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to DNA damage stimulus GO:0006974 9.43 MSH2 MUTYH SMUG1
2 DNA repair GO:0006281 9.33 MSH2 MUTYH SMUG1
3 base-excision repair GO:0006284 8.96 MUTYH SMUG1
4 mismatch repair GO:0006298 8.62 MSH2 MUTYH

Molecular functions related to Cecum Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA N-glycosylase activity GO:0019104 9.16 MUTYH SMUG1
2 MutLalpha complex binding GO:0032405 8.96 MSH2 MUTYH
3 oxidized purine DNA binding GO:0032357 8.62 MSH2 MUTYH

Sources for Cecum Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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