MCID: CFT005
MIFTS: 22

Ceftazidime Allergy

Categories: Immune diseases

Aliases & Classifications for Ceftazidime Allergy

MalaCards integrated aliases for Ceftazidime Allergy:

Name: Ceftazidime Allergy 12 15
Tazicef Allergy 12
Fortaz Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040024
SNOMED-CT 67 294546003
UMLS 70 C0571458

Summaries for Ceftazidime Allergy

Disease Ontology : 12 A cephalosporin allergy that has allergic trigger ceftazidime.

MalaCards based summary : Ceftazidime Allergy, also known as tazicef allergy, is related to cephalosporin allergy and oral tuberculosis. An important gene associated with Ceftazidime Allergy is MRGPRX2 (MAS Related GPR Family Member X2), and among its related pathways/superpathways are Innate Immune System and Allograft rejection. Affiliated tissues include skin and myeloid.

Related Diseases for Ceftazidime Allergy

Diseases related to Ceftazidime Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
# Related Disease Score Top Affiliating Genes
1 cephalosporin allergy 10.2 MRGPRX2 GNLY
2 oral tuberculosis 10.1 GNLY CD4
3 phenytoin allergy 10.1 GNLY CD4
4 drug allergy 10.1 MRGPRX2 CD4
5 immunodeficiency 43 10.0 HLA-E CD4
6 chronic nk-cell lymphocytosis 10.0 KLRD1 IL15
7 folliculitis 10.0 GNLY CD4
8 immunodeficiency 63 with lymphoproliferation and autoimmunity 10.0 IL7 IL15
9 immunodeficiency 13 9.9 IL7 CD4
10 severe cutaneous adverse reaction 9.9 MRGPRX2 GNLY CD4
11 immunodeficiency 41 with lymphoproliferation and autoimmunity 9.9 IL15 CD4
12 radiculopathy 9.8 IL7 IL15
13 bare lymphocyte syndrome, type i 9.8 KLRD1 HLA-E CD4
14 erythema infectiosum 9.8 EPO CD4
15 viral exanthem 9.8 EPO CD4
16 acute monoblastic leukemia 9.8 IL7 EPO
17 splenic sequestration 9.8 EPO CD4
18 coccidiosis 9.8 IL15 CD4
19 immunodeficiency 54 9.8 KLRD1 KLRC2 IL15
20 nk cell deficiency 9.8 KLRD1 KLRC2 IL15
21 miliary tuberculosis 9.8 EPO CD4
22 autoimmune disease of skin and connective tissue 9.8 IL15 CD4
23 iritis 9.8 EPO CD4
24 mycobacterium tuberculosis 1 9.8 IL7 GNLY CD4
25 severe combined immunodeficiency, x-linked 9.8 IL7 IL15
26 hypersplenism 9.8 EPO CD4
27 epidermodysplasia verruciformis 1 9.7 IL7 CD4
28 salmonellosis 9.7 IL15 CD4
29 disease by infectious agent 9.7 IL7 GNLY CD4
30 t cell deficiency 9.7 IL7 IL15 CD4
31 leukocyte disease 9.7 IL7 IL15 CD4
32 sezary's disease 9.7 IL7 IL15 CD4
33 contact dermatitis 9.7 IL7 IL15 CD4
34 human immunodeficiency virus infectious disease 9.7 IL7 IL15 CD4
35 viral infectious disease 9.6 IL7 IL15 CD4
36 acquired immunodeficiency syndrome 9.5 IL15 EPO CD4
37 psoriasis 9.4 KLRD1 IL7 IL15 CD4
38 celiac disease 1 9.3 KLRD1 KLRC2 IL15 HLA-E CD4
39 malaria 8.9 IL7 IL15 EPO CD4
40 leukemia, acute myeloid 8.8 KLRD1 KLRC2 IL7 IL15 EPO CD4

Graphical network of the top 20 diseases related to Ceftazidime Allergy:



Diseases related to Ceftazidime Allergy

Symptoms & Phenotypes for Ceftazidime Allergy

Drugs & Therapeutics for Ceftazidime Allergy

Search Clinical Trials , NIH Clinical Center for Ceftazidime Allergy

Genetic Tests for Ceftazidime Allergy

Anatomical Context for Ceftazidime Allergy

MalaCards organs/tissues related to Ceftazidime Allergy:

40
Skin, Myeloid

Publications for Ceftazidime Allergy

Articles related to Ceftazidime Allergy:

# Title Authors PMID Year
1
Allergic cross-sensitivity between penicillin, carbapenem, and monobactam antibiotics: what are the chances? 61
19193579 2009

Variations for Ceftazidime Allergy

Expression for Ceftazidime Allergy

Search GEO for disease gene expression data for Ceftazidime Allergy.

Pathways for Ceftazidime Allergy

Pathways related to Ceftazidime Allergy according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.51 KLRD1 KLRC2 IL7 IL15 HLA-E GNLY
2
Show member pathways
12.17 KLRD1 KLRC2 IL15 HLA-E GNLY CD4
3
Show member pathways
12.15 KLRD1 KLRC2 HLA-E
4
Show member pathways
12.03 IL7 IL15 EPO
5 11.92 IL15 HLA-E CD4
6 11.49 IL7 EPO CD4
7 11.36 KLRD1 IL7 IL15 CD4
8 11.12 KLRD1 HLA-E
9 11.09 KLRC2 IL7 IL15 EPO CD4
10 10.94 IL7 IL15
11 10.9 IL7 IL15 CD4

GO Terms for Ceftazidime Allergy

Cellular components related to Ceftazidime Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 IL7 IL15 HLA-E GNLY EPO
2 cell surface GO:0009986 8.92 IL15 HLA-E EPO CD4

Biological processes related to Ceftazidime Allergy according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.88 MRGPRX2 KLRC2 IL7 IL15 EPO CD4
2 immune response GO:0006955 9.67 IL7 IL15 HLA-E CD4
3 positive regulation of T cell proliferation GO:0042102 9.49 IL15 CD4
4 positive regulation of protein kinase activity GO:0045860 9.48 EPO CD4
5 cellular defense response GO:0006968 9.46 KLRC2 GNLY
6 macrophage differentiation GO:0030225 9.43 IL15 CD4
7 interleukin-15-mediated signaling pathway GO:0035723 9.32 IL15 CD4
8 negative regulation of natural killer cell mediated cytotoxicity GO:0045953 9.26 KLRD1 HLA-E
9 positive regulation of natural killer cell proliferation GO:0032819 9.16 IL15 HLA-E
10 natural killer cell mediated immunity GO:0002228 8.96 KLRD1 KLRC2
11 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 8.8 KLRD1 KLRC2 HLA-E

Molecular functions related to Ceftazidime Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 9.5 KLRD1 KLRC2 CD4
2 cytokine activity GO:0005125 9.43 IL7 IL15 EPO
3 cytokine receptor binding GO:0005126 9.16 IL7 IL15
4 protein antigen binding GO:1990405 8.96 KLRD1 KLRC2
5 MHC class I protein complex binding GO:0023024 8.62 KLRD1 KLRC2

Sources for Ceftazidime Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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