MCID: CFT003
MIFTS: 24

Ceftriaxone Allergy

Categories: Immune diseases

Aliases & Classifications for Ceftriaxone Allergy

MalaCards integrated aliases for Ceftriaxone Allergy:

Name: Ceftriaxone Allergy 12 15
Rocephin Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040005
SNOMED-CT 67 294551009
UMLS 71 C0571463

Summaries for Ceftriaxone Allergy

Disease Ontology : 12 A cephalosporin allergy that has allergic trigger ceftriaxone.

MalaCards based summary : Ceftriaxone Allergy, also known as rocephin allergy, is related to meningitis and acute myocarditis. An important gene associated with Ceftriaxone Allergy is ACOT1 (Acyl-CoA Thioesterase 1), and among its related pathways/superpathways are Th17 cell differentiation and JAK-STAT signaling pathway. Related phenotypes are hematopoietic system and respiratory system

Related Diseases for Ceftriaxone Allergy

Diseases related to Ceftriaxone Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 169)
# Related Disease Score Top Affiliating Genes
1 meningitis 29.3 IL5 IL13 IL10
2 acute myocarditis 10.1 MB IL10
3 femoral neuropathy 10.1 MB F3
4 dacryoadenitis 10.1 IL13 IL10
5 posterior cerebral artery infarction 10.1 MB F3
6 beta-lactam allergy 10.1 IL13 IL10
7 african tick-bite fever 10.1 IL13 IL10
8 fungal meningitis 10.1 IL13 IL10
9 penicillin allergy 10.0 IL13 IL10
10 trichuriasis 10.0 IL13 IL10
11 drug-induced lupus erythematosus 10.0 IL13 IL10
12 compartment syndrome 10.0 MB F3
13 anuria 10.0 MB F3
14 cryptococcosis 10.0 IL13 IL10
15 cerebral sinovenous thrombosis 10.0 IL10 F3
16 splenic disease 10.0 IL13 IL10
17 pericardium disease 10.0 MB F3
18 lipoid nephrosis 10.0 IL13 IL10
19 angina pectoris 10.0 MB F3
20 hand, foot and mouth disease 10.0 IL13 IL10
21 intermediate coronary syndrome 10.0 MB F3
22 cecal disease 10.0 IL10 F3
23 erythema nodosum 10.0 IL13 IL10
24 primary thrombocytopenia 10.0 IL10 F3
25 idiopathic interstitial pneumonia 10.0 IL13 CMA1
26 scrub typhus 10.0 IL10 F3
27 autoimmune disease of skin and connective tissue 9.9 IL13 IL10
28 nut allergy 9.9 IL5 IL13
29 autoimmune disease of cardiovascular system 9.9 IL10 F3
30 cytokine deficiency 9.9 IL5 IL13
31 angioimmunoblastic lymphadenopathy with dysproteinemia 9.9 IL5 IL13
32 respiratory syncytial virus infectious disease 9.9 IL5 IL13
33 cow milk allergy 9.9 IL5 IL10
34 loeffler syndrome 9.9 IL5 IL13
35 chronic asthma 9.9 IL5 IL13
36 orange allergy 9.9 IL5 IL13
37 brucellosis 9.9 IL13 IL10
38 pneumococcal meningitis 9.9
39 eosinophilic gastritis 9.9 IL5 IL13
40 pemphigoid 9.9 IL5 IL13
41 kimura disease 9.9 IL5 IL13
42 vernal keratoconjunctivitis 9.9 IL5 IL13
43 keratoconjunctivitis 9.9 IL5 IL13
44 mansonelliasis 9.9 IL5 IL10
45 mite infestation 9.9 IL5 IL13
46 paragonimiasis 9.9 IL5 IL13
47 endomyocardial fibrosis 9.9 IL5 IL10
48 intrinsic asthma 9.9 IL5 IL13
49 chronic meningitis 9.9 IL5 IL13
50 angiostrongyliasis 9.9 IL5 IL13

Graphical network of the top 20 diseases related to Ceftriaxone Allergy:



Diseases related to Ceftriaxone Allergy

Symptoms & Phenotypes for Ceftriaxone Allergy

MGI Mouse Phenotypes related to Ceftriaxone Allergy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.43 CMA1 F3 IL10 IL13 IL5 MB
2 respiratory system MP:0005388 9.02 F3 IL10 IL13 IL5 MB

Drugs & Therapeutics for Ceftriaxone Allergy

Search Clinical Trials , NIH Clinical Center for Ceftriaxone Allergy

Genetic Tests for Ceftriaxone Allergy

Anatomical Context for Ceftriaxone Allergy

Publications for Ceftriaxone Allergy

Articles related to Ceftriaxone Allergy:

# Title Authors PMID Year
1
Fatal adverse effects of injected ceftriaxone sodium in China. 61
22761158 2012
2
Cefazolin tolerance does not predict ceftriaxone hypersensitivity: unique side chains precipitate anaphylaxis. 61
15162902 2004
3
[Severe pneumococcal meningitis and ceftriaxone allergy]. 61
12033097 2002

Variations for Ceftriaxone Allergy

Expression for Ceftriaxone Allergy

Search GEO for disease gene expression data for Ceftriaxone Allergy.

Pathways for Ceftriaxone Allergy

GO Terms for Ceftriaxone Allergy

Cellular components related to Ceftriaxone Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 IL5 IL13 IL10 F3 CMA1
2 extracellular space GO:0005615 9.02 IL5 IL13 IL10 F3 CMA1

Biological processes related to Ceftriaxone Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of B cell proliferation GO:0030890 9.37 IL5 IL13
2 negative regulation of endothelial cell apoptotic process GO:2000352 9.32 IL13 IL10
3 positive regulation of JAK-STAT cascade GO:0046427 9.26 IL5 IL10
4 cytokine-mediated signaling pathway GO:0019221 9.26 IL5 IL13 IL10 F3
5 positive regulation of macrophage activation GO:0043032 9.16 IL13 IL10
6 positive regulation of immunoglobulin production GO:0002639 8.8 IL5 IL13 IL10

Molecular functions related to Ceftriaxone Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.8 IL5 IL13 IL10

Sources for Ceftriaxone Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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