MCID: CFT003
MIFTS: 23

Ceftriaxone Allergy

Categories: Immune diseases

Aliases & Classifications for Ceftriaxone Allergy

MalaCards integrated aliases for Ceftriaxone Allergy:

Name: Ceftriaxone Allergy 12 15
Rocephin Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040005
SNOMED-CT 67 294551009
UMLS 71 C0571463

Summaries for Ceftriaxone Allergy

Disease Ontology : 12 A cephalosporin allergy that has allergic trigger ceftriaxone.

MalaCards based summary : Ceftriaxone Allergy, also known as rocephin allergy, is related to cephalosporin allergy and cardiomyopathy, familial hypertrophic, 20. An important gene associated with Ceftriaxone Allergy is PEDS1 (Plasmanylethanolamine Desaturase 1), and among its related pathways/superpathways are Interleukin-10 signaling and Th2 Differentiation. The drug Complement System Proteins has been mentioned in the context of this disorder. Related phenotypes are hematopoietic system and muscle

Related Diseases for Ceftriaxone Allergy

Diseases related to Ceftriaxone Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 cephalosporin allergy 10.3 PEDS1 CMA1
2 cardiomyopathy, familial hypertrophic, 20 10.1 IL13 HCCS
3 drug allergy 10.1 PEDS1 IL5
4 cytokine deficiency 10.0 IL5 IL13
5 angioimmunoblastic lymphadenopathy with dysproteinemia 10.0 IL5 IL13
6 respiratory syncytial virus infectious disease 10.0 IL5 IL13
7 loeffler syndrome 10.0 IL5 IL13
8 eosinophilic gastritis 10.0 IL5 IL13
9 loiasis 10.0 IL5 IL13
10 mikulicz disease 10.0 IL5 IL13
11 trichinosis 10.0 IL5 IL13
12 cough variant asthma 10.0 IL5 IL13
13 vernal keratoconjunctivitis 10.0 IL5 IL13
14 stevens-johnson syndrome/toxic epidermal necrolysis 10.0 IL5 IL13
15 intrinsic asthma 10.0 IL5 IL13
16 paragonimiasis 10.0 IL5 IL13
17 chronic meningitis 9.9 IL5 IL13
18 angiostrongyliasis 9.9 IL5 IL13
19 elephantiasis 9.9 IL5 IL13
20 meningitis 9.9
21 pneumococcal meningitis 9.9
22 mucocutaneous leishmaniasis 9.9 IL5 IL13
23 chronic rhinitis 9.9 IL5 IL13
24 strongyloidiasis 9.9 IL5 IL13
25 eosinophilic meningitis 9.9 IL5 IL13
26 kimura disease 9.9 IL5 IL13
27 filarial elephantiasis 9.9 IL5 IL13
28 latex allergy 9.9 IL5 IL13
29 intestinal schistosomiasis 9.9 IL5 IL13
30 ascaris lumbricoides infection 9.9 IL5 IL13
31 hemopneumothorax 9.9 HCCS F3
32 hemopericardium 9.9 HCCS F3
33 urinary schistosomiasis 9.9 IL5 IL13
34 scleritis 9.9 TNFRSF1B IL5
35 status asthmaticus 9.9 IL5 IL13
36 erythema multiforme 9.9 IL5 IL13
37 radiculopathy 9.9 IL5 IL13
38 ige responsiveness, atopic 9.9 IL5 IL13
39 posterior cerebral artery infarction 9.9 MB F3
40 esophagitis, eosinophilic, 1 9.8 IL5 IL13
41 ebola hemorrhagic fever 9.8 MB F3
42 diabetic peripheral angiopathy 9.8 IL13 F3
43 anuria 9.8 MB F3
44 posterior uveitis 9.8 IL5 IL13
45 ankylosing spondylitis 1 9.8 TNFRSF1B F3
46 compartment syndrome 9.8 MB F3
47 eosinophilic pneumonia 9.8 IL5 IL13
48 onchocerciasis 9.8 IL5 IL13
49 nut allergy 9.8 PEDS1 IL5 IL13
50 egg allergy 9.8 PEDS1 IL5 IL13

Graphical network of the top 20 diseases related to Ceftriaxone Allergy:



Diseases related to Ceftriaxone Allergy

Symptoms & Phenotypes for Ceftriaxone Allergy

MGI Mouse Phenotypes related to Ceftriaxone Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 CMA1 F3 IL13 IL5 MB PEDS1
2 muscle MP:0005369 9.35 F3 HCCS IL13 MB TNFRSF1B
3 respiratory system MP:0005388 9.02 F3 IL13 IL5 MB TNFRSF1B

Drugs & Therapeutics for Ceftriaxone Allergy

Drugs for Ceftriaxone Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Soliris to Stop Immune Mediated Death In Covid 19 Infected Patients. A Trial of Distal Complement Inhibition. Available NCT04288713 Eculizumab

Search NIH Clinical Center for Ceftriaxone Allergy

Genetic Tests for Ceftriaxone Allergy

Anatomical Context for Ceftriaxone Allergy

Publications for Ceftriaxone Allergy

Articles related to Ceftriaxone Allergy:

# Title Authors PMID Year
1
Fatal adverse effects of injected ceftriaxone sodium in China. 61
22761158 2012
2
Cefazolin tolerance does not predict ceftriaxone hypersensitivity: unique side chains precipitate anaphylaxis. 61
15162902 2004
3
[Severe pneumococcal meningitis and ceftriaxone allergy]. 61
12033097 2002

Variations for Ceftriaxone Allergy

Expression for Ceftriaxone Allergy

Search GEO for disease gene expression data for Ceftriaxone Allergy.

Pathways for Ceftriaxone Allergy

Pathways related to Ceftriaxone Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.12 TNFRSF1B IL13
2 11.07 IL5 IL13
3 10.89 TNFRSF1B IL5
4 10.83 IL5 IL13
5 10.72 IL5 IL13
6 10.6 IL5 IL13 CMA1
7 10.57 IL5 IL13
8 10.03 IL5 IL13

GO Terms for Ceftriaxone Allergy

Biological processes related to Ceftriaxone Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of B cell proliferation GO:0030890 8.96 IL5 IL13
2 cytokine-mediated signaling pathway GO:0019221 8.92 TNFRSF1B IL5 IL13 F3

Sources for Ceftriaxone Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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