MCID: CFR002
MIFTS: 22

Cefuroxime Allergy

Categories: Immune diseases

Aliases & Classifications for Cefuroxime Allergy

MalaCards integrated aliases for Cefuroxime Allergy:

Name: Cefuroxime Allergy 12 15
Cephuroxime Allergy 12
Zinacef Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040025
SNOMED-CT 67 294542001
UMLS 71 C0571454

Summaries for Cefuroxime Allergy

Disease Ontology : 12 A cephalosporin allergy that has allergic trigger cefuroxime.

MalaCards based summary : Cefuroxime Allergy, also known as cephuroxime allergy, is related to bullous skin disease and vagus nerve disease. An important gene associated with Cefuroxime Allergy is ACOT1 (Acyl-CoA Thioesterase 1), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Ovarian steroidogenesis. Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Cefuroxime Allergy

Diseases related to Cefuroxime Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
# Related Disease Score Top Affiliating Genes
1 bullous skin disease 10.1 PPL IL5
2 vagus nerve disease 10.0 ATP4A ATP12A
3 acquired gastric outlet stenosis 10.0 ATP4A ATP12A
4 displacement of cardia through esophageal hiatus 10.0 ATP4A ATP12A
5 angiodysplasia of intestine 10.0 ATP4A ATP12A
6 angiodysplasia 10.0 ATP4A ATP12A
7 benzylpenicillin allergy 10.0 ATP4A ATP12A
8 granulomatous gastritis 10.0 ATP4A ATP12A
9 bacterial esophagitis 10.0 ATP4A ATP12A
10 lingual goiter 10.0 ATP4A ATP12A
11 cascade stomach 10.0 ATP4A ATP12A
12 gastrojejunal ulcer 10.0 ATP4A ATP12A
13 median arcuate ligament syndrome 10.0 ATP4A ATP12A
14 laryngeal tuberculosis 10.0 ATP4A ATP12A
15 fungal esophagitis 10.0 ATP4A ATP12A
16 dieulafoy lesion 10.0 ATP4A ATP12A
17 esophagus melanoma 10.0 ATP4A ATP12A
18 emphysematous cholecystitis 10.0 ATP4A ATP12A
19 necrotizing gastritis 10.0 ATP4A ATP12A
20 cervix erosion 10.0 ATP4A ATP12A
21 pneumatosis cystoides intestinalis 10.0 ATP4A ATP12A
22 gastric gastrinoma 10.0 ATP4A ATP12A
23 superior mesenteric artery syndrome 10.0 ATP4A ATP12A
24 chronic laryngitis 10.0 ATP4A ATP12A
25 laryngitis 10.0 ATP4A ATP12A
26 polyposis, skin pigmentation, alopecia, and fingernail changes 10.0 ATP4A ATP12A
27 chronic intestinal vascular insufficiency 10.0 ATP4A ATP12A
28 peptic ulcer perforation 10.0 ATP4A ATP12A
29 rumination disorder 10.0 ATP4A ATP12A
30 blind loop syndrome 10.0 ATP4A ATP12A
31 acute laryngitis 10.0 ATP4A ATP12A
32 gastroduodenitis 10.0 ATP4A ATP12A
33 duodenitis 10.0 ATP4A ATP12A
34 duodenal gastrinoma 10.0 ATP4A ATP12A
35 gastric hemangioma 10.0 ATP4A ATP12A
36 internal hemorrhoid 10.0 ATP4A ATP12A
37 hemorrhoid 10.0 ATP4A ATP12A
38 pancreatic gastrinoma 10.0 ATP4A ATP12A
39 gastric dilatation 10.0 ATP4A ATP12A
40 scalp dermatosis 10.0 ATP4A ATP12A
41 central nervous system origin vertigo 10.0 ATP4A ATP12A
42 diclofenac allergy 10.0 ATP4A ATP12A
43 lymphocytic gastritis 10.0 ATP4A ATP12A
44 x-linked chondrodysplasia punctata 1 10.0 ATP4A ATP12A
45 gastroduodenal crohn's disease 10.0 ATP4A ATP12A
46 duodenal obstruction 10.0 ATP4A ATP12A
47 gastric antral vascular ectasia 10.0 ATP4A ATP12A
48 functional diarrhea 10.0 ATP4A ATP12A
49 tropical sprue 10.0 ATP4A ATP12A
50 diarrhea 1, secretory chloride, congenital 10.0 ATP4A ATP12A

Graphical network of the top 20 diseases related to Cefuroxime Allergy:



Diseases related to Cefuroxime Allergy

Symptoms & Phenotypes for Cefuroxime Allergy

GenomeRNAi Phenotypes related to Cefuroxime Allergy according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-128 9.4 IL13
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-130 9.4 ATP12A EPHA6 IL13
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.4 EPHA6
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.4 ATP12A
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-29 9.4 ATP12A
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-39 9.4 IL13
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-43 9.4 EPHA6
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.4 PTGS2
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-79 9.4 PTGS2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-9 9.4 ATP12A

MGI Mouse Phenotypes related to Cefuroxime Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 ATP12A ATP4A IL13 IL5 PTGS2

Drugs & Therapeutics for Cefuroxime Allergy

Search Clinical Trials , NIH Clinical Center for Cefuroxime Allergy

Genetic Tests for Cefuroxime Allergy

Anatomical Context for Cefuroxime Allergy

Publications for Cefuroxime Allergy

Variations for Cefuroxime Allergy

Expression for Cefuroxime Allergy

Search GEO for disease gene expression data for Cefuroxime Allergy.

Pathways for Cefuroxime Allergy

Pathways related to Cefuroxime Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.77 PTGS2 IL5 IL13
2 11.14 PTGS2 ACOT1
3 11.09 PTGS2 IL13
4 11.03 IL5 IL13
5 10.83 IL5 IL13
6 10.62 IL5 IL13
7 10.37 IL5 IL13
8 9.7 IL5 IL13

GO Terms for Cefuroxime Allergy

Biological processes related to Cefuroxime Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.58 PTGS2 IL5 IL13
2 potassium ion import across plasma membrane GO:1990573 9.37 ATP4A ATP12A
3 positive regulation of B cell proliferation GO:0030890 9.32 IL5 IL13
4 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
5 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
6 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
7 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP4A ATP12A

Molecular functions related to Cefuroxime Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Cefuroxime Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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