CELIAC12
MCID: CLC044
MIFTS: 15

Celiac Disease 12 (CELIAC12)

Categories: Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Celiac Disease 12

MalaCards integrated aliases for Celiac Disease 12:

Name: Celiac Disease 12 56
Celiac Disease, Susceptibility to, 12 56 13
Gluten-Sensitive Enteropathy, Susceptibility to, 12 56
Gluten-Sensitive Enteropathy 12 56
Celiac12 56

Classifications:



External Ids:

OMIM 56 612010
OMIM Phenotypic Series 56 PS212750
MedGen 41 C2677602

Summaries for Celiac Disease 12

OMIM : 56 Celiac disease, also known as celiac sprue and gluten-sensitive enteropathy, is a multifactorial disorder of the small intestine that is influenced by both environmental and genetic factors. It is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins (summary by Farrell and Kelly, 2002). For additional information and a discussion of genetic heterogeneity of celiac disease, see 212750. (612010)

MalaCards based summary : Celiac Disease 12, also known as celiac disease, susceptibility to, 12, is related to celiac disease 1. An important gene associated with Celiac Disease 12 is CELIAC12 (Celiac Disease, Susceptibility To, 12). Affiliated tissues include small intestine.

Related Diseases for Celiac Disease 12

Diseases in the Celiac Disease 1 family:

Celiac Disease 5 Celiac Disease 4
Celiac Disease 2 Celiac Disease 3
Celiac Disease 6 Celiac Disease 7
Celiac Disease 8 Celiac Disease 9
Celiac Disease 10 Celiac Disease 11
Celiac Disease 12 Celiac Disease 13

Diseases related to Celiac Disease 12 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 celiac disease 1 11.3

Symptoms & Phenotypes for Celiac Disease 12

Clinical features from OMIM:

612010

Drugs & Therapeutics for Celiac Disease 12

Search Clinical Trials , NIH Clinical Center for Celiac Disease 12

Genetic Tests for Celiac Disease 12

Anatomical Context for Celiac Disease 12

MalaCards organs/tissues related to Celiac Disease 12:

40
Small Intestine

Publications for Celiac Disease 12

Articles related to Celiac Disease 12:

(show all 12)
# Title Authors PMID Year
1
Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease. 56
18805825 2009
2
Shared and distinct genetic variants in type 1 diabetes and celiac disease. 56
19073967 2008
3
Newly identified genetic risk variants for celiac disease related to the immune response. 56
18311140 2008
4
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. 56
17558408 2007
5
Celiac sprue. 56
11796853 2002
6
[Clinical features and management of 205 adults with type 1 diabetes mellitus]. 61
31344206 2019
7
Introduction of gluten, HLA status, and the risk of celiac disease in children. 61
25271602 2014
8
Increased prevalence of celiac disease among pediatric patients with irritable bowel syndrome: a 6-year prospective cohort study. 61
24756157 2014
9
Children diagnosed with diabetes during infancy have unique clinical characteristics. 61
17170528 2007
10
[Intestinal microbiocenosis in children with intestinal enzymopathy]. 61
11550576 2001
11
Reduced cadherin/catenin complex expression in celiac disease can be reproduced in vitro by cytokine stimulation. 61
10616200 1999
12
In siblings of celiac children, rectal gluten challenge reveals gluten sensitization not restricted to celiac HLA. 61
8690196 1996

Variations for Celiac Disease 12

Expression for Celiac Disease 12

Search GEO for disease gene expression data for Celiac Disease 12.

Pathways for Celiac Disease 12

GO Terms for Celiac Disease 12

Sources for Celiac Disease 12

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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