Cell Type Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: CLL012 MIFTS: 23	Cell Type Benign Neoplasm Categories: Cancer diseases
Genes Tissues Related diseases Pathways Expand all tables

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Aliases & Classifications for Cell Type Benign Neoplasm

MalaCards integrated aliases for Cell Type Benign Neoplasm:

Name: Cell Type Benign Neoplasm ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060084

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Summaries for Cell Type Benign Neoplasm

Disease Ontology : ¹² A benign neoplasm that is classified by the type of cell or tissue from which it is derived.

MalaCards based summary : Cell Type Benign Neoplasm is related to lipomatosis, multiple and gonadoblastoma. An important gene associated with Cell Type Benign Neoplasm is MIR17 (MicroRNA 17), and among its related pathways/superpathways are MicroRNAs in cancer and EV release from cardiac cells and their functional effects. Affiliated tissues include pituitary, bone and heart.

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Related Diseases for Cell Type Benign Neoplasm

Diseases related to Cell Type Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 267)

#	Related Disease	Score	Top Affiliating Genes
1	lipomatosis, multiple	11.1
2	gonadoblastoma	11.1
3	ameloblastoma	11.1
4	low grade glioma	11.1
5	leiomyoma	11.1
6	chondroma	11.1
7	adenomyoma	11.1
8	benign mesothelioma	11.1
9	adenofibroma	11.1
10	angiomyolipoma	11.1
11	ganglioglioma	11.1
12	adenoma	11.1
13	microcystic adenoma	10.6	SERPINA3 MIR21 MIR126
14	coronavirus infectious disease	10.6	SERPINA3 MIR17 H2AC18 CCR6
15	esophagus adenocarcinoma	10.6	MIR21 MIR199A1 MIR196A1 MIR143
16	tonsil cancer	10.6	SERPINA3 MIR199A1 H2AC18
17	parasitic helminthiasis infectious disease	10.6	SERPINA3 MIR21 H2AC18 CCR6
18	progressive relapsing multiple sclerosis	10.6	SERPINA3 H2AC18 CCR6
19	aortic valve disease 2	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR126
20	placenta disease	10.6	SERPINA3 MIR483 MIR199A1 H2AC18
21	vascular disease	10.6	MIR221 MIR21 MIR199A1 MIR143 MIR126
22	blood protein disease	10.6	MIR17 MIR126 H2AC18 CCR6
23	ovarian serous carcinoma	10.6	MIR93 MIR21 MIR199A1 MIR143
24	cerebral arterial disease	10.6	SERPINA3 MIR199A1 MIR143
25	chromosomal duplication syndrome	10.6	SERPINA3 MIR196A1 MIR126 H2AC18
26	central nervous system hematologic cancer	10.6	MIR199A1 MIR18A CCR6
27	heart valve disease	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR126 H2AC18
28	autoimmune disease of cardiovascular system	10.6	SERPINA3 H2AC18 CCR6
29	central nervous system benign neoplasm	10.6	SERPINA3 PRL POMC H2AC18
30	pleural disease	10.6	MIR199A1 MIR17 H2AC18 CCR6
31	reproductive organ benign neoplasm	10.6	SERPINA3 PRL H2AC18
32	testicular disease	10.6	SERPINA3 MIR199A1 H2AC18 CCR6
33	pleural cancer	10.6	MIR93 MIR17 MIR142 MIR139 H2AC18
34	rectum cancer	10.6	MIR483 MIR21 MIR17 MIR143 MIR139 MIR126
35	eye degenerative disease	10.6	SERPINA3 MIR17 H2AC18 CCR6
36	oropharynx cancer	10.6	SERPINA3 MIR199A1 H2AC18
37	adrenal cortex disease	10.6	POMC MIR483 MIR139 CCR6
38	acute cystitis	10.6	SERPINA3 H2AC18 CCR6
39	ovary adenocarcinoma	10.6	SERPINA3 MIR17 H2AC18
40	intermediate coronary syndrome	10.6	MIR144 MIR142 MIR126
41	autoimmune disease of skin and connective tissue	10.6	SERPINA3 H2AC18 CCR6
42	mature t-cell and nk-cell lymphoma	10.6	MIR199A1 MIR17 MIR126 H2AC18 CCR6
43	specific developmental disorder	10.6	SERPINA3 POMC MIR483 H2AC18
44	parasitic protozoa infectious disease	10.6	SERPINA3 MIR142 H2AC18 CCR6
45	endogenous depression	10.6	PRL POMC H2AC18
46	larynx cancer	10.6	MIR21 MIR196A1 MIR17 MIR143 MIR139
47	hair disease	10.6	SERPINA3 POMC H2AC18 CCR6
48	chromosomal deletion syndrome	10.6	MIR17 MIR142 H2AC18 CCR6
49	aortic disease	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR15A MIR126
50	muscle cancer	10.6	SERPINA3 MIR199A1 MIR196A1 MIR142 H2AC18

Graphical network of the top 20 diseases related to Cell Type Benign Neoplasm:

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Symptoms & Phenotypes for Cell Type Benign Neoplasm

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Drugs & Therapeutics for Cell Type Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Cell Type Benign Neoplasm

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Genetic Tests for Cell Type Benign Neoplasm

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Anatomical Context for Cell Type Benign Neoplasm

MalaCards organs/tissues related to Cell Type Benign Neoplasm:

⁴⁰

Pituitary, Bone, Heart, Skin, Cervix, Eye, Lung

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Publications for Cell Type Benign Neoplasm

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Genes for Cell Type Benign Neoplasm

Genes related to Cell Type Benign Neoplasm (0 elite genes):

(show top 50) (show all 80)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MIR17	MicroRNA 17	RNA Gene	11.66	DISEASES inferred ¹⁵ ¹⁵
2	MIR21	MicroRNA 21	RNA Gene	11.38	DISEASES inferred ¹⁵ ¹⁵
3	SERPINA3	Serpin Family A Member 3	Protein Coding	10.72	DISEASES inferred ¹⁵ ¹⁵
4	MIR18A	MicroRNA 18a	RNA Gene	10.67	DISEASES inferred ¹⁵ ¹⁵
5	H2AC18	H2A Clustered Histone 18	Protein Coding	10.58	DISEASES inferred ¹⁵ ¹⁵
6	MIR483	MicroRNA 483	RNA Gene	10.52	DISEASES inferred ¹⁵ ¹⁵
7	MIR143	MicroRNA 143	RNA Gene	10.36	DISEASES inferred ¹⁵ ¹⁵
8	MIR139	MicroRNA 139	RNA Gene	10.08	DISEASES inferred ¹⁵ ¹⁵
9	MIR126	MicroRNA 126	RNA Gene	9.98	DISEASES inferred ¹⁵ ¹⁵
10	MIR15A	MicroRNA 15a	RNA Gene	9.89	DISEASES inferred ¹⁵ ¹⁵
11	MIR221	MicroRNA 221	RNA Gene	9.85	DISEASES inferred ¹⁵ ¹⁵
12	MIR199A1	MicroRNA 199a-1	RNA Gene	9.77	DISEASES inferred ¹⁵ ¹⁵
13	MIR142	MicroRNA 142	RNA Gene	9.57	DISEASES inferred ¹⁵ ¹⁵
14	MIR196A1	MicroRNA 196a-1	RNA Gene	9.35	DISEASES inferred ¹⁵ ¹⁵
15	POMC	Proopiomelanocortin	Protein Coding	9.33	DISEASES inferred ¹⁵
16	MIR93	MicroRNA 93	RNA Gene	9.27	DISEASES inferred ¹⁵ ¹⁵
17	MIR532	MicroRNA 532	RNA Gene	9.26	DISEASES inferred ¹⁵ ¹⁵
18	MIR144	MicroRNA 144	RNA Gene	9.18	DISEASES inferred ¹⁵ ¹⁵
19	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	9.11	DISEASES inferred ¹⁵ ¹⁵
20	PRL	Prolactin	Protein Coding	9.08	DISEASES inferred ¹⁵
21	TP53	Tumor Protein P53	Protein Coding	9.05	DISEASES inferred ¹⁵
22	MIR15B	MicroRNA 15b	RNA Gene	9.05	DISEASES inferred ¹⁵ ¹⁵
23	MIR210	MicroRNA 210	RNA Gene	8.99	DISEASES inferred ¹⁵ ¹⁵
24	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	8.91	DISEASES inferred ¹⁵
25	MIR191	MicroRNA 191	RNA Gene	8.9	DISEASES inferred ¹⁵ ¹⁵
26	PTH	Parathyroid Hormone	Protein Coding	8.88	DISEASES inferred ¹⁵
27	MEN1	Menin 1	Protein Coding	8.83	DISEASES inferred ¹⁵
28	CTNNB1	Catenin Beta 1	Protein Coding	8.83	DISEASES inferred ¹⁵
29	MIR200A	MicroRNA 200a	RNA Gene	8.79	DISEASES inferred ¹⁵ ¹⁵
30	MIR29B1	MicroRNA 29b-1	RNA Gene	8.77	DISEASES inferred ¹⁵ ¹⁵
31	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	8.76	DISEASES inferred ¹⁵
32	SST	Somatostatin	Protein Coding	8.72	DISEASES inferred ¹⁵
33	MIR181A1	MicroRNA 181a-1	RNA Gene	8.7	DISEASES inferred ¹⁵ ¹⁵
34	MIR10A	MicroRNA 10a	RNA Gene	8.63	DISEASES inferred ¹⁵ ¹⁵
35	INS	Insulin	Protein Coding	8.55	DISEASES inferred ¹⁵
36	MIR125A	MicroRNA 125a	RNA Gene	8.5	DISEASES inferred ¹⁵ ¹⁵
37	MIR224	MicroRNA 224	RNA Gene	8.46	DISEASES inferred ¹⁵ ¹⁵
38	CD34	CD34 Molecule	Protein Coding	8.4	DISEASES inferred ¹⁵
39	MIR22	MicroRNA 22	RNA Gene	8.4	DISEASES inferred ¹⁵ ¹⁵
40	MIR582	MicroRNA 582	RNA Gene	8.38	DISEASES inferred ¹⁵ ¹⁵
41	REN	Renin	Protein Coding	8.37	DISEASES inferred ¹⁵
42	IGF1	Insulin Like Growth Factor 1	Protein Coding	8.32	DISEASES inferred ¹⁵
43	MIR127	MicroRNA 127	RNA Gene	8.23	DISEASES inferred ¹⁵ ¹⁵
44	MIR27B	MicroRNA 27b	RNA Gene	8.22	DISEASES inferred ¹⁵ ¹⁵
45	MIR30A	MicroRNA 30a	RNA Gene	8.19	DISEASES inferred ¹⁵ ¹⁵
46	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	8.16	DISEASES inferred ¹⁵
47	MIR338	MicroRNA 338	RNA Gene	8.15	DISEASES inferred ¹⁵ ¹⁵
48	TSC2	TSC Complex Subunit 2	Protein Coding	8.09	DISEASES inferred ¹⁵
49	CCND1	Cyclin D1	Protein Coding	8.08	DISEASES inferred ¹⁵
50	APC	APC Regulator Of WNT Signaling Pathway	Protein Coding	8.06	DISEASES inferred ¹⁵

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Variations for Cell Type Benign Neoplasm

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Expression for Cell Type Benign Neoplasm

Search GEO for disease gene expression data for Cell Type Benign Neoplasm.

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Pathways for Cell Type Benign Neoplasm

Pathways related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	MicroRNAs in cancer ³⁶	11.77	MIR483 MIR221 MIR21 MIR199A1 MIR18A MIR17
2	EV release from cardiac cells and their functional effects ¹	9.91	PRL MIR126

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GO Terms for Cell Type Benign Neoplasm

Cellular components related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.53	SERPINA3 PRL POMC MIR93 MIR532 MIR221
2	extracellular vesicle	GO:1903561	9.43	MIR93 MIR221 MIR21 MIR17 MIR15A MIR126

Biological processes related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 19)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of angiogenesis	GO:0045766	9.8	MIR21 MIR199A1 MIR143 MIR126
2	negative regulation of inflammatory response	GO:0050728	9.76	MIR221 MIR15A MIR142 MIR126
3	positive regulation of inflammatory response	GO:0050729	9.75	MIR21 MIR144 MIR126
4	positive regulation of protein kinase B signaling	GO:0051897	9.72	MIR221 MIR21 MIR199A1 MIR143 MIR126
5	positive regulation of vascular smooth muscle cell proliferation	GO:1904707	9.71	MIR221 MIR21 MIR17
6	negative regulation of angiogenesis	GO:0016525	9.71	PRL MIR21 MIR15A MIR143
7	positive regulation of blood vessel endothelial cell migration	GO:0043536	9.7	MIR221 MIR143 MIR126
8	negative regulation of sprouting angiogenesis	GO:1903671	9.61	MIR221 MIR18A MIR17
9	negative regulation of low-density lipoprotein particle clearance	GO:0010989	9.58	MIR199A1 MIR17
10	positive regulation of cardiac muscle hypertrophy in response to stress	GO:1903244	9.57	MIR199A1 MIR17
11	positive regulation of metalloendopeptidase activity	GO:1904685	9.56	MIR21 MIR17
12	negative regulation of vascular endothelial growth factor production	GO:1904046	9.56	MIR93 MIR199A1 MIR17 MIR15A
13	negative regulation of vascular associated smooth muscle cell apoptotic process	GO:1905460	9.55	MIR21 MIR17
14	negative regulation of cell migration involved in sprouting angiogenesis	GO:0090051	9.55	MIR483 MIR221 MIR199A1 MIR196A1 MIR15A
15	positive regulation of vascular associated smooth muscle cell migration	GO:1904754	9.54	MIR221 MIR21 MIR143
16	negative regulation of interleukin-21 production	GO:0032705	9.51	MIR221 MIR21
17	gene silencing by miRNA	GO:0035195	9.5	MIR93 MIR532 MIR483 MIR221 MIR21 MIR199A1
18	positive regulation of pulmonary blood vessel remodeling	GO:1905111	9.48	MIR17 MIR143
19	miRNA mediated inhibition of translation	GO:0035278	9.43	MIR483 MIR221 MIR21 MIR17 MIR15A MIR144

Molecular functions related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mRNA 3'-UTR binding	GO:0003730	9.61	MIR93 MIR21 MIR17 MIR15A MIR144 MIR143
2	mRNA binding involved in posttranscriptional gene silencing	GO:1903231	9.47	MIR93 MIR483 MIR221 MIR21 MIR199A1 MIR196A1

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