MCID: CLL012
MIFTS: 21

Cell Type Benign Neoplasm

Categories: Cancer diseases
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Aliases & Classifications for Cell Type Benign Neoplasm

MalaCards integrated aliases for Cell Type Benign Neoplasm:

Name: Cell Type Benign Neoplasm 11 14

Classifications:



External Ids:

Disease Ontology 11 DOID:0060084

Summaries for Cell Type Benign Neoplasm

Disease Ontology: 11 A benign neoplasm that is classified by the type of cell or tissue from which it is derived.

MalaCards based summary: Cell Type Benign Neoplasm is related to low grade glioma and lipomatosis, multiple. An important gene associated with Cell Type Benign Neoplasm is MIR21 (MicroRNA 21), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index.

Related Diseases for Cell Type Benign Neoplasm

Diseases related to Cell Type Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 312)
# Related Disease Score Top Affiliating Genes
1 low grade glioma 32.5 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR155 MIR142
2 lipomatosis, multiple 11.2
3 gonadoblastoma 11.2
4 ameloblastoma 11.2
5 leiomyoma 11.2
6 chondroma 11.2
7 adenomyoma 11.2
8 benign mesothelioma 11.2
9 adenofibroma 11.2
10 angiomyolipoma 11.2
11 ganglioglioma 11.2
12 adenoma 11.2
13 vascular disease 10.6 MIR21 MIR199A1 MIR145 MIR143 MIR126
14 glioma 10.6 MIR221 MIR21 MIR17 MIR15A
15 aortic aneurysm 10.6 MIR21 MIR15A MIR145 MIR126
16 cardiovascular organ benign neoplasm 10.6 SERPINA3 MIR199A1 MIR18A MIR17 MIR15A MIR143
17 bacterial infectious disease 10.6 SERPINA3 MIR21 MIR155 MIR144 H2AC18
18 colonic benign neoplasm 10.6 SERPINA3 MIR21 MIR199A1 MIR18A MIR15A MIR145
19 retinal vascular disease 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR126 H2AC18
20 oropharynx cancer 10.6 SERPINA3 MIR93 MIR21 MIR199A1 MIR139 H2AC18
21 bone deterioration disease 10.6 MIR9-1 MIR21 MIR17 MIR143 MIR126
22 aortic valve disease 2 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR126 H2AC18
23 intermediate coronary syndrome 10.6 MIR21 MIR17 MIR145 MIR142 MIR126
24 cystadenocarcinoma 10.6 SERPINA3 MIR21 MIR199A1
25 extrinsic cardiomyopathy 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR142 MIR126
26 mature t-cell and nk-cell lymphoma 10.6 MIR21 MIR199A1 MIR17 MIR155 H2AC18
27 pre-malignant neoplasm 10.6 SERPINA3 MIR17 MIR142 MIR139 H2AC18
28 ovarian serous carcinoma 10.6 MIR93 MIR21 MIR199A1 MIR145 MIR143 H2AC18
29 peripheral artery disease 10.6 MIR21 MIR199A1 MIR17 MIR126
30 heart valve disease 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR142 MIR126
31 pleural cancer 10.6 MIR93 MIR21 MIR199A1 MIR17 MIR142 MIR139
32 colon adenoma 10.6 MIR18A MIR15A MIR143 APC
33 microvascular complications of diabetes 5 10.6 MIR21 MIR199A1 MIR17 MIR126 H2AC18
34 ovarian cystadenocarcinoma 10.6 SERPINA3 MIR483 MIR17 H2AC18
35 pleural disease 10.6 MIR93 MIR21 MIR199A1 MIR17 MIR142 MIR139
36 skeletal muscle cancer 10.5 SERPINA3 MIR9-1 MIR483 MIR199A1 H2AC18
37 ovarian clear cell carcinoma 10.5 MIR9-1 MIR221 MIR21 MIR199A1 H2AC18
38 muscle cancer 10.5 SERPINA3 MIR9-1 MIR483 MIR199A1 H2AC18
39 intrahepatic cholangiocarcinoma 10.5 MIR199A1 MIR17 MIR142 MIR126 H2AC18
40 esophagus adenocarcinoma 10.5 MIR21 MIR199A1 MIR145 MIR143
41 uveal disease 10.5 SERPINA3 MIR9-1 MIR199A1 MIR17 MIR142 H2AC18
42 chromosomal deletion syndrome 10.5 MIR9-1 MIR21 MIR17 MIR142 H2AC18
43 colorectal adenoma 10.5 MIR31 MIR21 MIR18A MIR17 MIR15A MIR143
44 lymphangioma 10.5 SERPINA3 MIR199A1 MIR18A MIR15A MIR143 H2AC18
45 tonsil cancer 10.5 SERPINA3 MIR93 MIR199A1 H2AC18
46 lymph node disease 10.5 SERPINA3 MIR483 MIR145 H2AC18
47 amino acid metabolic disorder 10.5 SERPINA3 MIR199A1 MIR139 MIR126 H2AC18
48 serous cystadenocarcinoma 10.5 MIR21 MIR199A1 H2AC18
49 autoimmune disease of skin and connective tissue 10.5 SERPINA3 MIR21 MIR17 MIR155 MIR142 MIR126
50 rectal benign neoplasm 10.5 MIR31 MIR17 MIR145 MIR143

Graphical network of the top 20 diseases related to Cell Type Benign Neoplasm:



Diseases related to Cell Type Benign Neoplasm

Symptoms & Phenotypes for Cell Type Benign Neoplasm

Drugs & Therapeutics for Cell Type Benign Neoplasm

Search Clinical Trials, NIH Clinical Center for Cell Type Benign Neoplasm

Genetic Tests for Cell Type Benign Neoplasm

Anatomical Context for Cell Type Benign Neoplasm

Publications for Cell Type Benign Neoplasm

Variations for Cell Type Benign Neoplasm

Expression for Cell Type Benign Neoplasm

Search GEO for disease gene expression data for Cell Type Benign Neoplasm.

Pathways for Cell Type Benign Neoplasm

Pathways related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.43 MIR9-1 MIR21 MIR199A1 MIR155 MIR145 MIR126
2
Show member pathways
11.4 MIR9-1 MIR221 MIR199A1 MIR17 MIR155 MIR145
3 11.05 MIR93 MIR221 MIR21 MIR18A MIR17 MIR15A

GO Terms for Cell Type Benign Neoplasm

Cellular components related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.83 SERPINA3 MIR93 MIR31 MIR221 MIR21 MIR199A1
2 RISC complex GO:0016442 9.81 MIR126 MIR139 MIR142 MIR143 MIR144 MIR145
3 extracellular vesicle GO:1903561 9.63 MIR93 MIR221 MIR21 MIR17 MIR15A MIR126

Biological processes related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell population proliferation GO:0008285 10.16 MIR93 MIR9-1 MIR221 MIR21 MIR15A APC
2 miRNA-mediated gene silencing GO:0035195 10.1 MIR126 MIR139 MIR142 MIR143 MIR144 MIR145
3 positive regulation of angiogenesis GO:0045766 9.92 MIR31 MIR21 MIR199A1 MIR143 MIR126
4 negative regulation of angiogenesis GO:0016525 9.91 MIR21 MIR15A MIR145 MIR143
5 negative regulation of gene expression GO:0010629 9.91 MIR93 MIR9-1 MIR21 MIR199A1 MIR17 MIR155
6 positive regulation of protein kinase B signaling GO:0051897 9.85 MIR221 MIR21 MIR199A1 MIR143 MIR126
7 negative regulation of osteoblast differentiation GO:0045668 9.82 MIR93 MIR9-1 MIR17
8 positive regulation of vascular associated smooth muscle cell proliferation GO:1904707 9.82 MIR221 MIR21 MIR17
9 negative regulation of cell migration GO:0030336 9.8 MIR93 MIR9-1 MIR31 MIR21 MIR145 MIR126
10 negative regulation of cardiac muscle cell apoptotic process GO:0010667 9.77 MIR21 MIR199A1 MIR145
11 positive regulation of blood vessel endothelial cell migration GO:0043536 9.73 MIR126 MIR143 MIR221 MIR31
12 negative regulation of sprouting angiogenesis GO:1903671 9.72 MIR221 MIR18A MIR17
13 positive regulation of vascular associated smooth muscle cell migration GO:1904754 9.71 MIR221 MIR21 MIR143
14 negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 9.71 MIR483 MIR221 MIR199A1 MIR15A
15 negative regulation of inflammatory response GO:0050728 9.7 MIR126 MIR142 MIR145 MIR15A MIR199A1 MIR221
16 negative regulation of transporter activity GO:0032410 9.69 MIR93 MIR9-1 MIR17
17 angiotensin-activated signaling pathway GO:0038166 9.65 MIR145 MIR143
18 negative regulation of amyloid precursor protein biosynthetic process GO:0042985 9.65 MIR31 MIR17 MIR144
19 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.64 MIR199A1 MIR17
20 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.63 MIR21 MIR17
21 aorta smooth muscle tissue morphogenesis GO:0060414 9.63 MIR145 MIR143
22 positive regulation of metalloendopeptidase activity GO:1904685 9.62 MIR21 MIR17
23 negative regulation of leukocyte adhesion to vascular endothelial cell GO:1904995 9.61 MIR31 MIR221
24 negative regulation of BMP secretion GO:2001285 9.6 MIR93 MIR17
25 negative regulation of interleukin-21 production GO:0032705 9.58 MIR21 MIR221
26 regulation of phenotypic switching GO:1900239 9.58 MIR143 MIR145
27 positive regulation of pulmonary blood vessel remodeling GO:1905111 9.57 MIR17 MIR143
28 positive regulation of cellular response to hypoxia GO:1900039 9.56 MIR21 MIR145
29 negative regulation of vascular endothelial growth factor production GO:1904046 9.56 MIR93 MIR199A1 MIR17 MIR15A
30 establishment or maintenance of cell type involved in phenotypic switching GO:0044663 9.49 MIR145 MIR143
31 miRNA-mediated gene silencing by inhibition of translation GO:0035278 9.32 MIR126 MIR144 MIR145 MIR15A MIR17 MIR21

Molecular functions related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.83 MIR93 MIR9-1 MIR483 MIR31 MIR21 MIR199A1
2 mRNA base-pairing translational repressor activity GO:1903231 9.55 MIR93 MIR9-1 MIR483 MIR31 MIR221 MIR21

Sources for Cell Type Benign Neoplasm

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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