MCID: CLL012
MIFTS: 23

Cell Type Benign Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Cell Type Benign Neoplasm

MalaCards integrated aliases for Cell Type Benign Neoplasm:

Name: Cell Type Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060084

Summaries for Cell Type Benign Neoplasm

Disease Ontology : 12 A benign neoplasm that is classified by the type of cell or tissue from which it is derived.

MalaCards based summary : Cell Type Benign Neoplasm is related to lipomatosis, multiple and gonadoblastoma. An important gene associated with Cell Type Benign Neoplasm is MIR17 (MicroRNA 17), and among its related pathways/superpathways are MicroRNAs in cancer and EV release from cardiac cells and their functional effects. Affiliated tissues include pituitary, bone and heart.

Related Diseases for Cell Type Benign Neoplasm

Diseases related to Cell Type Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 267)
# Related Disease Score Top Affiliating Genes
1 lipomatosis, multiple 11.1
2 gonadoblastoma 11.1
3 ameloblastoma 11.1
4 low grade glioma 11.1
5 leiomyoma 11.1
6 chondroma 11.1
7 adenomyoma 11.1
8 benign mesothelioma 11.1
9 adenofibroma 11.1
10 angiomyolipoma 11.1
11 ganglioglioma 11.1
12 adenoma 11.1
13 microcystic adenoma 10.6 SERPINA3 MIR21 MIR126
14 coronavirus infectious disease 10.6 SERPINA3 MIR17 H2AC18 CCR6
15 esophagus adenocarcinoma 10.6 MIR21 MIR199A1 MIR196A1 MIR143
16 tonsil cancer 10.6 SERPINA3 MIR199A1 H2AC18
17 parasitic helminthiasis infectious disease 10.6 SERPINA3 MIR21 H2AC18 CCR6
18 progressive relapsing multiple sclerosis 10.6 SERPINA3 H2AC18 CCR6
19 aortic valve disease 2 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR126
20 placenta disease 10.6 SERPINA3 MIR483 MIR199A1 H2AC18
21 vascular disease 10.6 MIR221 MIR21 MIR199A1 MIR143 MIR126
22 blood protein disease 10.6 MIR17 MIR126 H2AC18 CCR6
23 ovarian serous carcinoma 10.6 MIR93 MIR21 MIR199A1 MIR143
24 cerebral arterial disease 10.6 SERPINA3 MIR199A1 MIR143
25 chromosomal duplication syndrome 10.6 SERPINA3 MIR196A1 MIR126 H2AC18
26 central nervous system hematologic cancer 10.6 MIR199A1 MIR18A CCR6
27 heart valve disease 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR126 H2AC18
28 autoimmune disease of cardiovascular system 10.6 SERPINA3 H2AC18 CCR6
29 central nervous system benign neoplasm 10.6 SERPINA3 PRL POMC H2AC18
30 pleural disease 10.6 MIR199A1 MIR17 H2AC18 CCR6
31 reproductive organ benign neoplasm 10.6 SERPINA3 PRL H2AC18
32 testicular disease 10.6 SERPINA3 MIR199A1 H2AC18 CCR6
33 pleural cancer 10.6 MIR93 MIR17 MIR142 MIR139 H2AC18
34 rectum cancer 10.6 MIR483 MIR21 MIR17 MIR143 MIR139 MIR126
35 eye degenerative disease 10.6 SERPINA3 MIR17 H2AC18 CCR6
36 oropharynx cancer 10.6 SERPINA3 MIR199A1 H2AC18
37 adrenal cortex disease 10.6 POMC MIR483 MIR139 CCR6
38 acute cystitis 10.6 SERPINA3 H2AC18 CCR6
39 ovary adenocarcinoma 10.6 SERPINA3 MIR17 H2AC18
40 intermediate coronary syndrome 10.6 MIR144 MIR142 MIR126
41 autoimmune disease of skin and connective tissue 10.6 SERPINA3 H2AC18 CCR6
42 mature t-cell and nk-cell lymphoma 10.6 MIR199A1 MIR17 MIR126 H2AC18 CCR6
43 specific developmental disorder 10.6 SERPINA3 POMC MIR483 H2AC18
44 parasitic protozoa infectious disease 10.6 SERPINA3 MIR142 H2AC18 CCR6
45 endogenous depression 10.6 PRL POMC H2AC18
46 larynx cancer 10.6 MIR21 MIR196A1 MIR17 MIR143 MIR139
47 hair disease 10.6 SERPINA3 POMC H2AC18 CCR6
48 chromosomal deletion syndrome 10.6 MIR17 MIR142 H2AC18 CCR6
49 aortic disease 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR15A MIR126
50 muscle cancer 10.6 SERPINA3 MIR199A1 MIR196A1 MIR142 H2AC18

Graphical network of the top 20 diseases related to Cell Type Benign Neoplasm:



Diseases related to Cell Type Benign Neoplasm

Symptoms & Phenotypes for Cell Type Benign Neoplasm

Drugs & Therapeutics for Cell Type Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Cell Type Benign Neoplasm

Genetic Tests for Cell Type Benign Neoplasm

Anatomical Context for Cell Type Benign Neoplasm

MalaCards organs/tissues related to Cell Type Benign Neoplasm:

40
Pituitary, Bone, Heart, Skin, Cervix, Eye, Lung

Publications for Cell Type Benign Neoplasm

Variations for Cell Type Benign Neoplasm

Expression for Cell Type Benign Neoplasm

Search GEO for disease gene expression data for Cell Type Benign Neoplasm.

Pathways for Cell Type Benign Neoplasm

Pathways related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.77 MIR483 MIR221 MIR21 MIR199A1 MIR18A MIR17
2 9.91 PRL MIR126

GO Terms for Cell Type Benign Neoplasm

Cellular components related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.53 SERPINA3 PRL POMC MIR93 MIR532 MIR221
2 extracellular vesicle GO:1903561 9.43 MIR93 MIR221 MIR21 MIR17 MIR15A MIR126

Biological processes related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of angiogenesis GO:0045766 9.8 MIR21 MIR199A1 MIR143 MIR126
2 negative regulation of inflammatory response GO:0050728 9.76 MIR221 MIR15A MIR142 MIR126
3 positive regulation of inflammatory response GO:0050729 9.75 MIR21 MIR144 MIR126
4 positive regulation of protein kinase B signaling GO:0051897 9.72 MIR221 MIR21 MIR199A1 MIR143 MIR126
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.71 MIR221 MIR21 MIR17
6 negative regulation of angiogenesis GO:0016525 9.71 PRL MIR21 MIR15A MIR143
7 positive regulation of blood vessel endothelial cell migration GO:0043536 9.7 MIR221 MIR143 MIR126
8 negative regulation of sprouting angiogenesis GO:1903671 9.61 MIR221 MIR18A MIR17
9 negative regulation of low-density lipoprotein particle clearance GO:0010989 9.58 MIR199A1 MIR17
10 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.57 MIR199A1 MIR17
11 positive regulation of metalloendopeptidase activity GO:1904685 9.56 MIR21 MIR17
12 negative regulation of vascular endothelial growth factor production GO:1904046 9.56 MIR93 MIR199A1 MIR17 MIR15A
13 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.55 MIR21 MIR17
14 negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 9.55 MIR483 MIR221 MIR199A1 MIR196A1 MIR15A
15 positive regulation of vascular associated smooth muscle cell migration GO:1904754 9.54 MIR221 MIR21 MIR143
16 negative regulation of interleukin-21 production GO:0032705 9.51 MIR221 MIR21
17 gene silencing by miRNA GO:0035195 9.5 MIR93 MIR532 MIR483 MIR221 MIR21 MIR199A1
18 positive regulation of pulmonary blood vessel remodeling GO:1905111 9.48 MIR17 MIR143
19 miRNA mediated inhibition of translation GO:0035278 9.43 MIR483 MIR221 MIR21 MIR17 MIR15A MIR144

Molecular functions related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.61 MIR93 MIR21 MIR17 MIR15A MIR144 MIR143
2 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.47 MIR93 MIR483 MIR221 MIR21 MIR199A1 MIR196A1

Sources for Cell Type Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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