Cell Type Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cell Type Benign Neoplasm

MalaCards integrated aliases for Cell Type Benign Neoplasm:

Name: Cell Type Benign Neoplasm ¹¹ ¹⁴

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:0060084

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Summaries for Cell Type Benign Neoplasm

Disease Ontology: ¹¹ A benign neoplasm that is classified by the type of cell or tissue from which it is derived.

MalaCards based summary: Cell Type Benign Neoplasm is related to low grade glioma and lipomatosis, multiple. An important gene associated with Cell Type Benign Neoplasm is MIR21 (MicroRNA 21), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index.

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Related Diseases for Cell Type Benign Neoplasm

Diseases related to Cell Type Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 312)

#	Related Disease	Score	Top Affiliating Genes
1	low grade glioma	32.5	SERPINA3 MIR9-1 MIR21 MIR199A1 MIR155 MIR142
2	lipomatosis, multiple	11.2
3	gonadoblastoma	11.2
4	ameloblastoma	11.2
5	leiomyoma	11.2
6	chondroma	11.2
7	adenomyoma	11.2
8	benign mesothelioma	11.2
9	adenofibroma	11.2
10	angiomyolipoma	11.2
11	ganglioglioma	11.2
12	adenoma	11.2
13	vascular disease	10.6	MIR21 MIR199A1 MIR145 MIR143 MIR126
14	glioma	10.6	MIR221 MIR21 MIR17 MIR15A
15	aortic aneurysm	10.6	MIR21 MIR15A MIR145 MIR126
16	cardiovascular organ benign neoplasm	10.6	SERPINA3 MIR199A1 MIR18A MIR17 MIR15A MIR143
17	bacterial infectious disease	10.6	SERPINA3 MIR21 MIR155 MIR144 H2AC18
18	colonic benign neoplasm	10.6	SERPINA3 MIR21 MIR199A1 MIR18A MIR15A MIR145
19	retinal vascular disease	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR126 H2AC18
20	oropharynx cancer	10.6	SERPINA3 MIR93 MIR21 MIR199A1 MIR139 H2AC18
21	bone deterioration disease	10.6	MIR9-1 MIR21 MIR17 MIR143 MIR126
22	aortic valve disease 2	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR126 H2AC18
23	intermediate coronary syndrome	10.6	MIR21 MIR17 MIR145 MIR142 MIR126
24	cystadenocarcinoma	10.6	SERPINA3 MIR21 MIR199A1
25	extrinsic cardiomyopathy	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR142 MIR126
26	mature t-cell and nk-cell lymphoma	10.6	MIR21 MIR199A1 MIR17 MIR155 H2AC18
27	pre-malignant neoplasm	10.6	SERPINA3 MIR17 MIR142 MIR139 H2AC18
28	ovarian serous carcinoma	10.6	MIR93 MIR21 MIR199A1 MIR145 MIR143 H2AC18
29	peripheral artery disease	10.6	MIR21 MIR199A1 MIR17 MIR126
30	heart valve disease	10.6	SERPINA3 MIR21 MIR199A1 MIR17 MIR142 MIR126
31	pleural cancer	10.6	MIR93 MIR21 MIR199A1 MIR17 MIR142 MIR139
32	colon adenoma	10.6	MIR18A MIR15A MIR143 APC
33	microvascular complications of diabetes 5	10.6	MIR21 MIR199A1 MIR17 MIR126 H2AC18
34	ovarian cystadenocarcinoma	10.6	SERPINA3 MIR483 MIR17 H2AC18
35	pleural disease	10.6	MIR93 MIR21 MIR199A1 MIR17 MIR142 MIR139
36	skeletal muscle cancer	10.5	SERPINA3 MIR9-1 MIR483 MIR199A1 H2AC18
37	ovarian clear cell carcinoma	10.5	MIR9-1 MIR221 MIR21 MIR199A1 H2AC18
38	muscle cancer	10.5	SERPINA3 MIR9-1 MIR483 MIR199A1 H2AC18
39	intrahepatic cholangiocarcinoma	10.5	MIR199A1 MIR17 MIR142 MIR126 H2AC18
40	esophagus adenocarcinoma	10.5	MIR21 MIR199A1 MIR145 MIR143
41	uveal disease	10.5	SERPINA3 MIR9-1 MIR199A1 MIR17 MIR142 H2AC18
42	chromosomal deletion syndrome	10.5	MIR9-1 MIR21 MIR17 MIR142 H2AC18
43	colorectal adenoma	10.5	MIR31 MIR21 MIR18A MIR17 MIR15A MIR143
44	lymphangioma	10.5	SERPINA3 MIR199A1 MIR18A MIR15A MIR143 H2AC18
45	tonsil cancer	10.5	SERPINA3 MIR93 MIR199A1 H2AC18
46	lymph node disease	10.5	SERPINA3 MIR483 MIR145 H2AC18
47	amino acid metabolic disorder	10.5	SERPINA3 MIR199A1 MIR139 MIR126 H2AC18
48	serous cystadenocarcinoma	10.5	MIR21 MIR199A1 H2AC18
49	autoimmune disease of skin and connective tissue	10.5	SERPINA3 MIR21 MIR17 MIR155 MIR142 MIR126
50	rectal benign neoplasm	10.5	MIR31 MIR17 MIR145 MIR143

Graphical network of the top 20 diseases related to Cell Type Benign Neoplasm:

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Symptoms & Phenotypes for Cell Type Benign Neoplasm

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Drugs & Therapeutics for Cell Type Benign Neoplasm

Search Clinical Trials, NIH Clinical Center for Cell Type Benign Neoplasm

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Genetic Tests for Cell Type Benign Neoplasm

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Anatomical Context for Cell Type Benign Neoplasm

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Publications for Cell Type Benign Neoplasm

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Genes for Cell Type Benign Neoplasm

Genes related to Cell Type Benign Neoplasm (0 elite genes):

(show top 50) (show all 92)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MIR21	MicroRNA 21	RNA Gene	11.2	DISEASES inferred ¹⁴ ¹⁴
2	MIR17	MicroRNA 17	RNA Gene	11.18	DISEASES inferred ¹⁴ ¹⁴
3	APC	APC Regulator Of WNT Signaling Pathway	Protein Coding	11.01	DISEASES inferred ¹⁴ ¹⁴
4	H2AC18	H2A Clustered Histone 18	Protein Coding	10.92	DISEASES inferred ¹⁴ ¹⁴
5	MIR18A	MicroRNA 18a	RNA Gene	10.52	DISEASES inferred ¹⁴ ¹⁴
6	SERPINA3	Serpin Family A Member 3	Protein Coding	10.45	DISEASES inferred ¹⁴ ¹⁴
7	MIR139	MicroRNA 139	RNA Gene	10.37	DISEASES inferred ¹⁴ ¹⁴
8	MIR483	MicroRNA 483	RNA Gene	10.13	DISEASES inferred ¹⁴ ¹⁴
9	MIR143	MicroRNA 143	RNA Gene	9.96	DISEASES inferred ¹⁴ ¹⁴
10	MIR126	MicroRNA 126	RNA Gene	9.67	DISEASES inferred ¹⁴ ¹⁴
11	MIR199A1	MicroRNA 199a-1	RNA Gene	9.66	DISEASES inferred ¹⁴ ¹⁴
12	MIR145	MicroRNA 145	RNA Gene	9.58	DISEASES inferred ¹⁴ ¹⁴
13	MIR93	MicroRNA 93	RNA Gene	9.55	DISEASES inferred ¹⁴ ¹⁴
14	MIR9-1	MicroRNA 9-1	RNA Gene	9.53	DISEASES inferred ¹⁴ ¹⁴
15	MIR142	MicroRNA 142	RNA Gene	9.49	DISEASES inferred ¹⁴ ¹⁴
16	MIR15A	MicroRNA 15a	RNA Gene	9.45	DISEASES inferred ¹⁴ ¹⁴
17	MIR31	MicroRNA 31	RNA Gene	9.37	DISEASES inferred ¹⁴ ¹⁴
18	MIR221	MicroRNA 221	RNA Gene	9.32	DISEASES inferred ¹⁴ ¹⁴
19	MIR144	MicroRNA 144	RNA Gene	9.27	DISEASES inferred ¹⁴ ¹⁴
20	MIR155	MicroRNA 155	RNA Gene	9.26	DISEASES inferred ¹⁴ ¹⁴
21	MIR196A1	MicroRNA 196a-1	RNA Gene	9.26	DISEASES inferred ¹⁴ ¹⁴
22	POMC	Proopiomelanocortin	Protein Coding	9.14	DISEASES inferred ¹⁴
23	MIR532	MicroRNA 532	RNA Gene	9.08	DISEASES inferred ¹⁴ ¹⁴
24	TP53	Tumor Protein P53	Protein Coding	9.08	DISEASES inferred ¹⁴
25	MIR210	MicroRNA 210	RNA Gene	9.03	DISEASES inferred ¹⁴ ¹⁴
26	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	9	DISEASES inferred ¹⁴ ¹⁴
27	MIR29B1	MicroRNA 29b-1	RNA Gene	8.98	DISEASES inferred ¹⁴ ¹⁴
28	MIR15B	MicroRNA 15b	RNA Gene	8.98	DISEASES inferred ¹⁴ ¹⁴
29	MIR224	MicroRNA 224	RNA Gene	8.95	DISEASES inferred ¹⁴ ¹⁴
30	MIR200A	MicroRNA 200a	RNA Gene	8.95	DISEASES inferred ¹⁴ ¹⁴
31	MIR195	MicroRNA 195	RNA Gene	8.9	DISEASES inferred ¹⁴ ¹⁴
32	MIR125A	MicroRNA 125a	RNA Gene	8.88	DISEASES inferred ¹⁴ ¹⁴
33	MIR106B	MicroRNA 106b	RNA Gene	8.87	DISEASES inferred ¹⁴ ¹⁴
34	PRL	Prolactin	Protein Coding	8.86	DISEASES inferred ¹⁴
35	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	8.81	DISEASES inferred ¹⁴
36	MIR193A	MicroRNA 193a	RNA Gene	8.79	DISEASES inferred ¹⁴ ¹⁴
37	MIR10B	MicroRNA 10b	RNA Gene	8.73	DISEASES inferred ¹⁴ ¹⁴
38	CTNNB1	Catenin Beta 1	Protein Coding	8.72	DISEASES inferred ¹⁴
39	MIRLET7B	MicroRNA Let-7b	RNA Gene	8.68	DISEASES inferred ¹⁴ ¹⁴
40	MEN1	Menin 1	Protein Coding	8.68	DISEASES inferred ¹⁴
41	PTH	Parathyroid Hormone	Protein Coding	8.66	DISEASES inferred ¹⁴
42	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	8.64	DISEASES inferred ¹⁴
43	KDM4C	Lysine Demethylase 4C	Protein Coding	8.61	DISEASES inferred ¹⁴ ¹⁴
44	MIR22	MicroRNA 22	RNA Gene	8.57	DISEASES inferred ¹⁴ ¹⁴
45	MIR181A1	MicroRNA 181a-1	RNA Gene	8.56	DISEASES inferred ¹⁴ ¹⁴
46	MIR338	MicroRNA 338	RNA Gene	8.52	DISEASES inferred ¹⁴ ¹⁴
47	SST	Somatostatin	Protein Coding	8.51	DISEASES inferred ¹⁴
48	MIR205	MicroRNA 205	RNA Gene	8.5	DISEASES inferred ¹⁴ ¹⁴
49	MIR106A	MicroRNA 106a	RNA Gene	8.49	DISEASES inferred ¹⁴ ¹⁴
50	MIR30A	MicroRNA 30a	RNA Gene	8.48	DISEASES inferred ¹⁴ ¹⁴

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Variations for Cell Type Benign Neoplasm

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Expression for Cell Type Benign Neoplasm

Search GEO for disease gene expression data for Cell Type Benign Neoplasm.

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Pathways for Cell Type Benign Neoplasm

Pathways related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	miRNAs involvement in the immune response in sepsis ⁷⁴	11.43	MIR9-1 MIR21 MIR199A1 MIR155 MIR145 MIR126
2	Cell differentiation - expanded index ⁷⁴ Show member pathways Cell differentiation - index ⁷⁴	11.4	MIR9-1 MIR221 MIR199A1 MIR17 MIR155 MIR145
3	miRNAs involved in DNA damage response ⁷⁴	11.05	MIR93 MIR221 MIR21 MIR18A MIR17 MIR15A

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GO Terms for Cell Type Benign Neoplasm

Cellular components related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.83	SERPINA3 MIR93 MIR31 MIR221 MIR21 MIR199A1
2	RISC complex	GO:0016442	9.81	MIR126 MIR139 MIR142 MIR143 MIR144 MIR145
3	extracellular vesicle	GO:1903561	9.63	MIR93 MIR221 MIR21 MIR17 MIR15A MIR126

Biological processes related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 31)

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of cell population proliferation	GO:0008285	10.16	MIR93 MIR9-1 MIR221 MIR21 MIR15A APC
2	miRNA-mediated gene silencing	GO:0035195	10.1	MIR126 MIR139 MIR142 MIR143 MIR144 MIR145
3	positive regulation of angiogenesis	GO:0045766	9.92	MIR31 MIR21 MIR199A1 MIR143 MIR126
4	negative regulation of angiogenesis	GO:0016525	9.91	MIR21 MIR15A MIR145 MIR143
5	negative regulation of gene expression	GO:0010629	9.91	MIR93 MIR9-1 MIR21 MIR199A1 MIR17 MIR155
6	positive regulation of protein kinase B signaling	GO:0051897	9.85	MIR221 MIR21 MIR199A1 MIR143 MIR126
7	negative regulation of osteoblast differentiation	GO:0045668	9.82	MIR93 MIR9-1 MIR17
8	positive regulation of vascular associated smooth muscle cell proliferation	GO:1904707	9.82	MIR221 MIR21 MIR17
9	negative regulation of cell migration	GO:0030336	9.8	MIR93 MIR9-1 MIR31 MIR21 MIR145 MIR126
10	negative regulation of cardiac muscle cell apoptotic process	GO:0010667	9.77	MIR21 MIR199A1 MIR145
11	positive regulation of blood vessel endothelial cell migration	GO:0043536	9.73	MIR126 MIR143 MIR221 MIR31
12	negative regulation of sprouting angiogenesis	GO:1903671	9.72	MIR221 MIR18A MIR17
13	positive regulation of vascular associated smooth muscle cell migration	GO:1904754	9.71	MIR221 MIR21 MIR143
14	negative regulation of cell migration involved in sprouting angiogenesis	GO:0090051	9.71	MIR483 MIR221 MIR199A1 MIR15A
15	negative regulation of inflammatory response	GO:0050728	9.7	MIR126 MIR142 MIR145 MIR15A MIR199A1 MIR221
16	negative regulation of transporter activity	GO:0032410	9.69	MIR93 MIR9-1 MIR17
17	angiotensin-activated signaling pathway	GO:0038166	9.65	MIR145 MIR143
18	negative regulation of amyloid precursor protein biosynthetic process	GO:0042985	9.65	MIR31 MIR17 MIR144
19	positive regulation of cardiac muscle hypertrophy in response to stress	GO:1903244	9.64	MIR199A1 MIR17
20	negative regulation of vascular associated smooth muscle cell apoptotic process	GO:1905460	9.63	MIR21 MIR17
21	aorta smooth muscle tissue morphogenesis	GO:0060414	9.63	MIR145 MIR143
22	positive regulation of metalloendopeptidase activity	GO:1904685	9.62	MIR21 MIR17
23	negative regulation of leukocyte adhesion to vascular endothelial cell	GO:1904995	9.61	MIR31 MIR221
24	negative regulation of BMP secretion	GO:2001285	9.6	MIR93 MIR17
25	negative regulation of interleukin-21 production	GO:0032705	9.58	MIR21 MIR221
26	regulation of phenotypic switching	GO:1900239	9.58	MIR143 MIR145
27	positive regulation of pulmonary blood vessel remodeling	GO:1905111	9.57	MIR17 MIR143
28	positive regulation of cellular response to hypoxia	GO:1900039	9.56	MIR21 MIR145
29	negative regulation of vascular endothelial growth factor production	GO:1904046	9.56	MIR93 MIR199A1 MIR17 MIR15A
30	establishment or maintenance of cell type involved in phenotypic switching	GO:0044663	9.49	MIR145 MIR143
31	miRNA-mediated gene silencing by inhibition of translation	GO:0035278	9.32	MIR126 MIR144 MIR145 MIR15A MIR17 MIR21

Molecular functions related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mRNA 3'-UTR binding	GO:0003730	9.83	MIR93 MIR9-1 MIR483 MIR31 MIR21 MIR199A1
2	mRNA base-pairing translational repressor activity	GO:1903231	9.55	MIR93 MIR9-1 MIR483 MIR31 MIR221 MIR21

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Sources for Cell Type Benign Neoplasm

¹ BitterDB

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⁵¹ NIH Clinical Center

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⁵³ Novoseek

⁵⁴ Novus Biologicals

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⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

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⁶¹ PubChem

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⁶⁵ R&D Systems

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⁶⁸ SNOMED-CT

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⁷⁰ Tocris

⁷¹ UMLS

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⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: CLL012 MIFTS: 21	Cell Type Benign Neoplasm Categories: Cancer diseases	Data Licensing For inquiries, contact: [email protected]
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