MCID: CLL012
MIFTS: 24

Cell Type Benign Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Cell Type Benign Neoplasm

MalaCards integrated aliases for Cell Type Benign Neoplasm:

Name: Cell Type Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060084

Summaries for Cell Type Benign Neoplasm

Disease Ontology : 12 A benign neoplasm that is classified by the type of cell or tissue from which it is derived.

MalaCards based summary : Cell Type Benign Neoplasm is related to lipomatosis, multiple and gonadoblastoma. An important gene associated with Cell Type Benign Neoplasm is MIR17 (MicroRNA 17), and among its related pathways/superpathways are MicroRNAs in cancer and Proteoglycans in cancer. Affiliated tissues include breast, thyroid and bone.

Related Diseases for Cell Type Benign Neoplasm

Diseases related to Cell Type Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 270)
# Related Disease Score Top Affiliating Genes
1 lipomatosis, multiple 11.2
2 gonadoblastoma 11.2
3 ameloblastoma 11.2
4 leiomyoma 11.2
5 chondroma 11.2
6 benign mesothelioma 11.2
7 adenofibroma 11.2
8 angiomyolipoma 11.2
9 ganglioglioma 11.2
10 adenoma 11.2
11 thyroid gland anaplastic carcinoma 10.8 TP53 MIR18A MIR17
12 cystadenocarcinoma 10.8 TP53 SERPINA3 MIR199A1 HRAS
13 pleural cancer 10.8 TP53 MIR17 MIR139 H2AC18
14 esophagus adenocarcinoma 10.8 TP53 MIR21 MIR143
15 signet ring basal cell carcinoma 10.8 KRAS HRAS
16 pancreatic acinar cell adenocarcinoma 10.8 SERPINA3 KRAS HRAS
17 tonsil cancer 10.8 TP53 SERPINA3 MIR199A1 H2AC18
18 cardiovascular cancer 10.8 TP53 SERPINA3 MIR143
19 collagen disease 10.8 SERPINA3 MIR21 MIR142 H2AC18
20 vascular cancer 10.8 TP53 SERPINA3 MIR143
21 paronychia 10.8 SERPINA3 KRAS HRAS
22 wolffian duct adenocarcinoma 10.8 TP53 KRAS HRAS
23 biliary tract benign neoplasm 10.8 TP53 KRAS HRAS
24 tumor of exocrine pancreas 10.8 TP53 KRAS HRAS
25 cerebral arterial disease 10.8 SERPINA3 MIR143 MIR126
26 trachea carcinoma in situ 10.8 KRAS HRAS
27 appendix disease 10.8 TP53 KRAS HRAS
28 breast carcinoma in situ 10.8 TP53 MIR17 MIR143 MIR142
29 luminal breast carcinoma 10.8 TP53 MIR21 H2AC18
30 testicular disease 10.8 TP53 SERPINA3 MIR199A1 H2AC18
31 retinal vascular disease 10.8 MIR21 MIR199A1 MIR126 H2AC18
32 lymphatic system disease 10.8 TP53 SERPINA3 MIR483 MIR17 H2AC18
33 mature teratoma 10.8 TP53 KRAS H2AC18
34 autoimmune disease of musculoskeletal system 10.8 SERPINA3 MIR21 MIR142 H2AC18
35 adrenal cortical carcinoma 10.8 TP53 POMC MIR483 MIR139
36 endometrioid ovary carcinoma 10.8 TP53 KRAS HRAS H2AC18
37 appendix cancer 10.8 TP53 KRAS HRAS
38 infratentorial cancer 10.8 TP53 MIR18A MIR17 MIR142 H2AC18
39 parasitic helminthiasis infectious disease 10.8 SERPINA3 MIR21 H2AC18
40 nasal cavity adenocarcinoma 10.8 KRAS HRAS
41 papillary adenoma 10.8 TP53 KRAS HRAS
42 adrenal cortex disease 10.8 TP53 POMC MIR483 MIR139
43 oropharynx cancer 10.8 TP53 SERPINA3 HRAS H2AC18
44 bronchiolo-alveolar adenocarcinoma 10.8 MIR31 MIR17 MIR126 KRAS
45 functioning pituitary adenoma 10.8 POMC MIR199A1 MIR142
46 heart valve disease 10.8 SERPINA3 MIR21 MIR199A1 MIR126
47 adrenal gland disease 10.8 TP53 POMC MIR483 MIR139
48 aortic valve disease 2 10.8 SERPINA3 MIR21 MIR199A1 MIR17 MIR126
49 anus cancer 10.8 TP53 KRAS HRAS H2AC18
50 nasal cavity cancer 10.8 TP53 KRAS HRAS

Graphical network of the top 20 diseases related to Cell Type Benign Neoplasm:



Diseases related to Cell Type Benign Neoplasm

Symptoms & Phenotypes for Cell Type Benign Neoplasm

Drugs & Therapeutics for Cell Type Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Cell Type Benign Neoplasm

Genetic Tests for Cell Type Benign Neoplasm

Anatomical Context for Cell Type Benign Neoplasm

MalaCards organs/tissues related to Cell Type Benign Neoplasm:

40
Breast, Thyroid, Bone, Lung, Colon, Skin, Ovary

Publications for Cell Type Benign Neoplasm

Variations for Cell Type Benign Neoplasm

Expression for Cell Type Benign Neoplasm

Search GEO for disease gene expression data for Cell Type Benign Neoplasm.

Pathways for Cell Type Benign Neoplasm

Pathways related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.96 TP53 MIR483 MIR31 MIR224 MIR21 MIR200A
2 11.57 TP53 MIR21 KRAS HRAS
3 11.36 TP53 KRAS HRAS
4 11.27 TP53 KRAS HRAS
5 11.14 TP53 KRAS HRAS
6 10.48 KRAS HRAS

GO Terms for Cell Type Benign Neoplasm

Cellular components related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.4 SERPINA3 POMC MIR532 MIR31 MIR21 MIR199A1

Biological processes related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.85 HRAS MIR17 MIR21 TP53
2 positive regulation of protein kinase B signaling GO:0051897 9.76 MIR126 MIR143 MIR199A1 MIR21
3 Ras protein signal transduction GO:0007265 9.7 HRAS KRAS TP53
4 positive regulation of angiogenesis GO:0045766 9.65 MIR126 MIR143 MIR199A1 MIR21 MIR31
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.61 MIR135B MIR17 MIR21
6 miRNA mediated inhibition of translation GO:0035278 9.55 MIR135B MIR17 MIR21 MIR31 MIR483
7 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.54 MIR17 MIR199A1
8 positive regulation of vascular associated smooth muscle cell migration GO:1904754 9.54 MIR135B MIR143 MIR21
9 positive regulation of metalloendopeptidase activity GO:1904685 9.51 MIR17 MIR21
10 positive regulation of vascular endothelial cell proliferation GO:1905564 9.5 MIR126 MIR135B MIR21
11 response to isolation stress GO:0035900 9.49 HRAS KRAS
12 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.48 MIR17 MIR21
13 positive regulation of pulmonary blood vessel remodeling GO:1905111 9.4 MIR143 MIR17
14 gene silencing by miRNA GO:0035195 9.36 MIR483 MIR31 MIR224 MIR21 MIR200A MIR199A1
15 positive regulation of blood vessel endothelial cell migration GO:0043536 9.35 MIR126 MIR135B MIR143 MIR200A MIR31

Molecular functions related to Cell Type Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.36 MIR483 MIR31 MIR224 MIR21 MIR200A MIR199A1

Sources for Cell Type Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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