MCID: CLL013
MIFTS: 29

Cell Type Cancer

Categories: Cancer diseases, Genetic diseases, Rare diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Cell Type Cancer

MalaCards integrated aliases for Cell Type Cancer:

Name: Cell Type Cancer 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050687

Summaries for Cell Type Cancer

Disease Ontology : 12 A cancer that is classified by the type of cell from which it is derived.

MalaCards based summary : Cell Type Cancer is related to germ cell cancer and colorectal cancer. An important gene associated with Cell Type Cancer is MIR199A1 (MicroRNA 199a-1), and among its related pathways/superpathways are MicroRNAs in cancer and Cell Differentiation - Index. Affiliated tissues include thyroid, bone and breast.

Related Diseases for Cell Type Cancer

Diseases in the Small Cell Carcinoma family:

Basal Cell Carcinoma 1 Basal Cell Carcinoma 2
Basal Cell Carcinoma 3 Basal Cell Carcinoma 4
Basal Cell Carcinoma 5 Basal Cell Carcinoma 6
Basal Cell Carcinoma 7 Cell Type Cancer
Basal Cell Carcinoma Large Cell Carcinoma
Basal Cell Carcinoma, Multiple

Diseases related to Cell Type Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 226)
# Related Disease Score Top Affiliating Genes
1 germ cell cancer 32.3 MIR9-1 MIR199A1 H2AC18
2 colorectal cancer 31.0 MIR9-1 MIR34A MIR31 MIR30A MIR221 MIR21
3 mixed cell type cancer 12.4
4 reproductive system disease 11.1 SERPINA3 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A
5 nervous system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
6 lung cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
7 gastrointestinal system disease 11.1 SERPINA3 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A
8 intestinal disease 11.1 SERPINA3 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A
9 gastrointestinal system cancer 11.1 SERPINA3 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A
10 female reproductive system disease 11.1 SERPINA3 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A
11 stomach disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
12 pancreas disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
13 male reproductive system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
14 thoracic cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
15 breast disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
16 prostate disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
17 endocrine system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
18 urinary system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
19 male reproductive organ cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
20 endocrine gland cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
21 gonadal disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
22 respiratory system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
23 hematologic cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
24 nervous system cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR21 MIR200A
25 respiratory system cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
26 uterine anomalies 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
27 hepatocellular carcinoma 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
28 large intestine cancer 11.1 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A MIR221
29 arteries, anomalies of 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR221 MIR21
30 colonic disease 11.1 MIR9-1 MIR34A MIR31 MIR30A MIR221 MIR21
31 leukocyte disease 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR21 MIR200B
32 lung cancer susceptibility 3 11.1 SERPINA3 MIR9-1 MIR31 MIR30A MIR21 MIR200B
33 connective tissue disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR221
34 bladder disease 11.1 MIR9-1 MIR34A MIR31 MIR30A MIR221 MIR21
35 cervix disease 11.1 SERPINA3 MIR9-1 MIR34A MIR31 MIR30A MIR21
36 leukemia, chronic lymphocytic 11.1 MIR9-1 MIR34A MIR31 MIR30A MIR221 MIR21
37 renal cell carcinoma, nonpapillary 11.1 MIR9-1 MIR34A MIR30A MIR221 MIR21 MIR200A
38 immune system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR221 MIR21
39 central nervous system disease 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR221 MIR21
40 leukemia, acute myeloid 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR221 MIR21
41 oral cavity cancer 11.1 SERPINA3 MIR9-1 MIR31 MIR30A MIR21 MIR199A1
42 pharynx cancer 11.1 SERPINA3 MIR9-1 MIR31 MIR30A MIR21 MIR199A1
43 lymphoma, non-hodgkin, familial 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR21 MIR200B
44 ovarian cancer 11.1 MIR9-1 MIR34A MIR31 MIR30A MIR221 MIR21
45 acquired metabolic disease 11.1 SERPINA3 MIR9-1 MIR31 MIR30A MIR21 MIR200A
46 mouth disease 11.1 SERPINA3 MIR9-1 MIR31 MIR221 MIR21 MIR199A1
47 glucose metabolism disease 11.1 SERPINA3 MIR9-1 MIR30A MIR21 MIR199A1 MIR196A1
48 central nervous system cancer 11.1 SERPINA3 MIR9-1 MIR34A MIR30A MIR21 MIR199A1
49 overnutrition 11.1 SERPINA3 MIR9-1 MIR34A MIR21 MIR199A1 MIR196A1
50 esophageal disease 11.1 MIR34A MIR30A MIR21 MIR200B MIR199A1 MIR196A1

Graphical network of the top 20 diseases related to Cell Type Cancer:



Diseases related to Cell Type Cancer

Symptoms & Phenotypes for Cell Type Cancer

Drugs & Therapeutics for Cell Type Cancer

Search Clinical Trials , NIH Clinical Center for Cell Type Cancer

Genetic Tests for Cell Type Cancer

Anatomical Context for Cell Type Cancer

MalaCards organs/tissues related to Cell Type Cancer:

40
Thyroid, Bone, Breast, Skin, Colon, Heart, Cervix

Publications for Cell Type Cancer

Articles related to Cell Type Cancer:

# Title Authors PMID Year
1
Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment. 61
31480642 2019
2
CellMarker: a manually curated resource of cell markers in human and mouse. 61
30289549 2019
3
ADARs and editing: The role of A-to-I RNA modification in cancer progression. 61
29146145 2018
4
Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells. 61
28260101 2017
5
Factors Influencing the Success of the First Radioiodine Therapy for Differentiated Thyroid Carcinoma. 61
29916638 2017
6
Prevalence and outcomes of peritumor fat involvement following partial nephrectomy for radiologic T1 renal cancer. 61
26692661 2015
7
Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. 61
21960545 2012
8
Risk factors for myocardial infarction in cancer patients. 61
8721899 1995
9
Comparison of Lauren's, Ming's and WHO histological classifications of gastric cancer as a prognostic factor for operated patients. 61
8063551 1994
10
[A case of signet-ring cell type cancer of the colon]. 61
2846911 1988

Variations for Cell Type Cancer

Expression for Cell Type Cancer

Search GEO for disease gene expression data for Cell Type Cancer.

Pathways for Cell Type Cancer

Pathways related to Cell Type Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.96 MIR9-1 MIR34A MIR31 MIR30A MIR221 MIR21
2 10.71 MIR9-1 MIR221 MIR199A1
3 10.27 MIR199A1 MIR145

GO Terms for Cell Type Cancer

Cellular components related to Cell Type Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.36 SERPINA3 MIR31 MIR30A MIR221 MIR21 MIR199A1

Biological processes related to Cell Type Cancer according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.91 MIR21 MIR200B MIR17 MIR125A
2 positive regulation of angiogenesis GO:0045766 9.8 MIR31 MIR30A MIR21 MIR199A1 MIR143 MIR126
3 positive regulation of protein kinase B signaling GO:0051897 9.77 MIR221 MIR21 MIR199A1 MIR143 MIR126
4 negative regulation of angiogenesis GO:0016525 9.73 MIR34A MIR21 MIR200B MIR145 MIR143 MIR125A
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.72 MIR221 MIR21 MIR17
6 negative regulation of cardiac muscle cell apoptotic process GO:0010667 9.69 MIR21 MIR199A1 MIR145
7 negative regulation of sprouting angiogenesis GO:1903671 9.67 MIR34A MIR221 MIR17
8 positive regulation of cardiac muscle cell apoptotic process GO:0010666 9.63 MIR34A MIR17
9 positive regulation of sprouting angiogenesis GO:1903672 9.63 MIR31 MIR126 MIR125A
10 positive regulation of blood vessel endothelial cell migration GO:0043536 9.63 MIR31 MIR30A MIR221 MIR200A MIR143 MIR126
11 negative regulation of cardiac muscle hypertrophy GO:0010614 9.62 MIR21 MIR145
12 regulation of smooth muscle contraction GO:0006940 9.62 MIR145 MIR143
13 negative regulation of low-density lipoprotein particle clearance GO:0010989 9.61 MIR199A1 MIR17
14 positive regulation of vascular associated smooth muscle cell migration GO:1904754 9.61 MIR221 MIR21 MIR143
15 positive regulation of connective tissue replacement GO:1905205 9.6 MIR34A MIR199A1
16 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.59 MIR199A1 MIR17
17 positive regulation of metalloendopeptidase activity GO:1904685 9.58 MIR21 MIR17
18 angiotensin-activated signaling pathway GO:0038166 9.58 MIR145 MIR143
19 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.57 MIR21 MIR17
20 negative regulation of leukocyte adhesion to vascular endothelial cell GO:1904995 9.56 MIR31 MIR221
21 miRNA mediated inhibition of translation GO:0035278 9.56 MIR9-1 MIR31 MIR30A MIR221 MIR21 MIR200B
22 aorta smooth muscle tissue morphogenesis GO:0060414 9.54 MIR145 MIR143
23 gene silencing by miRNA GO:0035195 9.53 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A MIR221
24 regulation of phenotypic switching GO:1900239 9.52 MIR145 MIR143
25 positive regulation of pulmonary blood vessel remodeling GO:1905111 9.48 MIR17 MIR143
26 establishment or maintenance of cell type involved in phenotypic switching GO:0044663 9.4 MIR145 MIR143

Molecular functions related to Cell Type Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.53 MIR9-1 MIR518A1 MIR34A MIR31 MIR30A MIR221
2 RNA polymerase II complex binding GO:0000993 9.13 MIR145 MIR126 MIR125A

Sources for Cell Type Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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