MCID: CLL007
MIFTS: 30

Cellular Congenital Mesoblastic Nephroma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Cellular Congenital Mesoblastic Nephroma

MalaCards integrated aliases for Cellular Congenital Mesoblastic Nephroma:

Name: Cellular Congenital Mesoblastic Nephroma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:8082
NCIt 50 C39815
UMLS 73 C1516474

Summaries for Cellular Congenital Mesoblastic Nephroma

MalaCards based summary : Cellular Congenital Mesoblastic Nephroma is related to congenital mesoblastic nephroma and nephrocalcinosis. An important gene associated with Cellular Congenital Mesoblastic Nephroma is NTRK3 (Neurotrophic Receptor Tyrosine Kinase 3), and among its related pathways/superpathways are ERK Signaling and TGF-Beta Pathway. Affiliated tissues include bone, kidney and breast.

Related Diseases for Cellular Congenital Mesoblastic Nephroma

Graphical network of the top 20 diseases related to Cellular Congenital Mesoblastic Nephroma:



Diseases related to Cellular Congenital Mesoblastic Nephroma

Symptoms & Phenotypes for Cellular Congenital Mesoblastic Nephroma

Drugs & Therapeutics for Cellular Congenital Mesoblastic Nephroma

Search Clinical Trials , NIH Clinical Center for Cellular Congenital Mesoblastic Nephroma

Genetic Tests for Cellular Congenital Mesoblastic Nephroma

Anatomical Context for Cellular Congenital Mesoblastic Nephroma

MalaCards organs/tissues related to Cellular Congenital Mesoblastic Nephroma:

41
Bone, Kidney, Breast, Thyroid, B Cells, Myeloid, Bone Marrow

Publications for Cellular Congenital Mesoblastic Nephroma

Articles related to Cellular Congenital Mesoblastic Nephroma:

(show all 11)
# Title Authors Year
1
Cellular Congenital Mesoblastic Nephroma in a Newborn. ( 28770142 )
2017
2
Cellular congenital mesoblastic nephroma: case report. ( 21541470 )
2011
3
Cellular congenital mesoblastic nephroma with contralateral medullary nephrocalcinosis. ( 15121709 )
2004
4
Complete response of recurrent cellular congenital mesoblastic nephroma to chemotherapy. ( 12218597 )
2002
5
Mixed epithelial and stromal tumor of the kidney lacks the genetic alterations of cellular congenital mesoblastic nephroma. ( 11381370 )
2001
6
Detection of the ETV6-NTRK3 chimeric RNA of infantile fibrosarcoma/cellular congenital mesoblastic nephroma in paraffin-embedded tissue: application to challenging pediatric renal stromal tumors. ( 10658907 )
2000
7
Ultrastructure of cellular congenital mesoblastic nephroma. ( 8883325 )
1996
8
Preoperative chemotherapy of cellular congenital mesoblastic nephroma in a 5-month-old infant. ( 1281666 )
1992
9
Cellular congenital mesoblastic nephroma: what are the options. ( 2545932 )
1989
10
Two chromosomally different cell populations in a partly cellular congenital mesoblastic nephroma. ( 3030229 )
1987
11
Cellular congenital mesoblastic nephroma in a newborn. ( 6097889 )
1984

Variations for Cellular Congenital Mesoblastic Nephroma

Expression for Cellular Congenital Mesoblastic Nephroma

Search GEO for disease gene expression data for Cellular Congenital Mesoblastic Nephroma.

Pathways for Cellular Congenital Mesoblastic Nephroma

Pathways related to Cellular Congenital Mesoblastic Nephroma according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.67 GAB2 NRAS NTRK3 SRC STAT5A STAT5B
2
Show member pathways
13.36 NRAS NTRK3 SRC STAT5A STAT5B
3
Show member pathways
13.22 GAB2 NRAS NTRK3 SRC STAT5A STAT5B
4
Show member pathways
13.19 GAB2 NRAS SRC STAT5A STAT5B
5
Show member pathways
12.9 NRAS SRC STAT5A STAT5B
6
Show member pathways
12.77 NRAS SRC STAT5A STAT5B
7
Show member pathways
12.73 NRAS SRC STAT5A STAT5B
8
Show member pathways
12.66 NRAS SRC STAT5A STAT5B
9
Show member pathways
12.64 GAB2 NRAS SRC STAT5A STAT5B
10
Show member pathways
12.63 NRAS SRC STAT5A STAT5B
11
Show member pathways
12.57 GAB2 NRAS NTRK3 SRC
12
Show member pathways
12.53 NRAS SRC STAT5A STAT5B
13
Show member pathways
12.45 NRAS SRC STAT5A STAT5B
14
Show member pathways
12.33 NRAS SRC STAT5A STAT5B
15 12.29 NRAS STAT5A STAT5B
16
Show member pathways
12.29 GAB2 NRAS SRC STAT5A
17
Show member pathways
12.28 GAB2 NRAS SRC
18
Show member pathways
12.26 GAB2 STAT5A STAT5B
19
Show member pathways
12.26 NRAS NTRK3 SRC STAT5A
20
Show member pathways
12.26 NRAS SRC STAT5A STAT5B
21
Show member pathways
12.16 GAB2 NRAS STAT5A STAT5B
22
Show member pathways
12.13 NRAS SRC STAT5B
23 12.08 NRAS SRC STAT5A STAT5B
24
Show member pathways
12.07 GAB2 NRAS SRC
25
Show member pathways
12.03 GAB2 NRAS NTRK3 SRC
26 12.01 GAB2 NRAS NTRK3
27
Show member pathways
12.01 GAB2 NRAS SRC STAT5A STAT5B
28
Show member pathways
11.96 GAB2 STAT5A STAT5B
29 11.95 GAB2 SRC STAT5A STAT5B
30
Show member pathways
11.91 GAB2 SRC STAT5A STAT5B
31
Show member pathways
11.87 GAB2 NRAS STAT5A STAT5B
32
Show member pathways
11.85 GAB2 STAT5A STAT5B
33
Show member pathways
11.84 NRAS STAT5A STAT5B
34 11.8 NRAS STAT5A STAT5B
35
Show member pathways
11.79 SRC STAT5A STAT5B
36 11.78 NTRK3 SRC STAT5A STAT5B
37 11.66 SRC STAT5A STAT5B
38
Show member pathways
11.57 GAB2 STAT5A STAT5B
39 11.55 SRC STAT5A STAT5B
40 11.5 NRAS SRC STAT5A STAT5B
41 11.47 GAB2 STAT5A
42 11.44 SRC STAT5A STAT5B
43 11.41 NRAS SRC
44 11.4 SRC STAT5B
45 11.39 SRC STAT5A STAT5B
46
Show member pathways
11.38 STAT5A STAT5B
47 11.37 NTRK3 SRC
48 11.33 STAT5A STAT5B
49
Show member pathways
11.33 STAT5A STAT5B
50 11.31 STAT5A STAT5B

GO Terms for Cellular Congenital Mesoblastic Nephroma

Biological processes related to Cellular Congenital Mesoblastic Nephroma according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.78 GAB2 STAT5A STAT5B
2 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.63 GAB2 NTRK3 SRC
3 lactation GO:0007595 9.6 STAT5A STAT5B
4 activation of protein kinase B activity GO:0032148 9.59 NTRK3 SRC
5 interleukin-7-mediated signaling pathway GO:0038111 9.58 STAT5A STAT5B
6 regulation of multicellular organism growth GO:0040014 9.58 STAT5A STAT5B
7 JAK-STAT cascade GO:0007259 9.57 STAT5A STAT5B
8 2-oxoglutarate metabolic process GO:0006103 9.56 STAT5A STAT5B
9 interleukin-15-mediated signaling pathway GO:0035723 9.55 STAT5A STAT5B
10 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.54 STAT5A STAT5B
11 creatine metabolic process GO:0006600 9.52 STAT5A STAT5B
12 interleukin-2-mediated signaling pathway GO:0038110 9.51 STAT5A STAT5B
13 oxaloacetate metabolic process GO:0006107 9.49 STAT5A STAT5B
14 succinate metabolic process GO:0006105 9.48 STAT5A STAT5B
15 interleukin-9-mediated signaling pathway GO:0038113 9.43 STAT5A STAT5B
16 citrate metabolic process GO:0006101 9.4 STAT5A STAT5B
17 taurine metabolic process GO:0019530 9.37 STAT5A STAT5B
18 valine metabolic process GO:0006573 9.32 STAT5A STAT5B
19 creatinine metabolic process GO:0046449 9.26 STAT5A STAT5B
20 isoleucine metabolic process GO:0006549 9.16 STAT5A STAT5B
21 allantoin metabolic process GO:0000255 8.96 STAT5A STAT5B
22 peptidyl-tyrosine phosphorylation GO:0018108 8.92 NTRK3 SRC STAT5A STAT5B

Molecular functions related to Cellular Congenital Mesoblastic Nephroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 8.92 NTRK3 SRC STAT5A STAT5B

Sources for Cellular Congenital Mesoblastic Nephroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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