MCID: CLL007
MIFTS: 19

Cellular Congenital Mesoblastic Nephroma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Cellular Congenital Mesoblastic Nephroma

MalaCards integrated aliases for Cellular Congenital Mesoblastic Nephroma:

Name: Cellular Congenital Mesoblastic Nephroma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:8082
NCIt 50 C39815
UMLS 70 C1516474

Summaries for Cellular Congenital Mesoblastic Nephroma

MalaCards based summary : Cellular Congenital Mesoblastic Nephroma is related to nephroma and congenital fibrosarcoma. An important gene associated with Cellular Congenital Mesoblastic Nephroma is NUTM2B (NUT Family Member 2B), and among its related pathways/superpathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and Cell cycle Role of 14-3-3 proteins in cell cycle regulation.

Related Diseases for Cellular Congenital Mesoblastic Nephroma

Diseases related to Cellular Congenital Mesoblastic Nephroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 nephroma 31.4 NTRK3 ETV6
2 congenital fibrosarcoma 30.6 VGLL2 NTRK3 ETV6
3 clear cell sarcoma 30.4 YWHAE NUTM2B CCNB3
4 kidney rhabdoid cancer 30.1 YWHAE NUTM2B CCNB3
5 congenital mesoblastic nephroma 29.3 YWHAE VGLL2 SSX2 NUTM2B NTRK3 ETV6
6 fibrosarcoma 10.4
7 rhabdoid cancer 10.4
8 wilms tumor 1 10.2
9 nephrocalcinosis 10.2
10 conventional fibrosarcoma 10.2
11 polyploidy 10.2
12 adult fibrosarcoma 10.2 NTRK3 ETV6
13 breast secretory carcinoma 10.2 NTRK3 ETV6
14 breast adenoid cystic carcinoma 10.2 NTRK3 ETV6
15 lipid-rich carcinoma 10.2 NTRK3 ETV6
16 mammary analogue secretory carcinoma 10.2 NTRK3 ETV6
17 cerebellar angioblastoma 10.1 NTRK3 ETV6
18 kidney benign neoplasm 10.1 NTRK3 ETV6
19 infantile myofibromatosis 10.1 NTRK3 ETV6
20 acinar cell carcinoma 10.1 NTRK3 ETV6
21 tonsil cancer 10.1 NTRK3 ETV6
22 oropharynx cancer 10.1 NTRK3 ETV6
23 salivary gland disease 10.0 NTRK3 ETV6
24 small cell osteogenic sarcoma 10.0 SATB2 CCNB3
25 conventional central osteosarcoma 10.0 SATB2 CCNB3
26 endometrial stromal tumor 9.9 YWHAE NUTM2B CCNB3
27 endometrial stromal sarcoma 9.8 YWHAE NUTM2B CCNB3
28 differentiated thyroid carcinoma 9.8 NTRK3 ETV6
29 malignant glandular tumor of peripheral nerve sheath 9.8 TLE1 SSX2
30 synovium neoplasm 9.8 TLE1 SSX2
31 bone osteosarcoma 9.8 SATB2 CCNB3
32 epithelioid malignant peripheral nerve sheath tumor 9.7 TLE1 SSX2
33 biphasic synovial sarcoma 9.7 TLE1 SSX2
34 monophasic synovial sarcoma 9.7 TLE1 SSX2
35 skeletal muscle cancer 9.7 VGLL2 SSX2
36 pediatric fibrosarcoma 9.7 VGLL2 NTRK3 ETV6 CCNB3
37 hemangiopericytoma, malignant 9.7 TLE1 SSX2
38 mesenchymal cell neoplasm 9.7 SSX2 NTRK3 CCNB3
39 rhabdomyosarcoma 2 9.7 VGLL2 SSX2 CCNB3
40 myxofibrosarcoma 9.6 TLE1 SSX2
41 spindle cell synovial sarcoma 9.6 TLE1 SSX2 CCNB3
42 synovium cancer 9.5 TLE1 SSX2 CCNB3
43 chondrosarcoma, extraskeletal myxoid 9.5 TLE1 SSX2 CCNB3
44 sarcoma, synovial 9.5 TLE1 SSX2 CCNB3
45 kidney fibrosarcoma 9.5 YWHAE SSX2 NTRK3 ETV6
46 kidney cortex disease 9.3 SSX2 NUTM2B NTRK3 ETV6 CCNB3
47 spindle cell sarcoma 8.9 VGLL2 TLE1 SSX2 NTRK3 ETV6 CCNB3
48 kidney clear cell sarcoma 8.9 YWHAE VGLL2 TLE1 SATB2 NUTM2B NTRK3
49 kidney sarcoma 8.6 YWHAE VGLL2 TLE1 SSX2 SATB2 NUTM2B

Graphical network of the top 20 diseases related to Cellular Congenital Mesoblastic Nephroma:



Diseases related to Cellular Congenital Mesoblastic Nephroma

Symptoms & Phenotypes for Cellular Congenital Mesoblastic Nephroma

Drugs & Therapeutics for Cellular Congenital Mesoblastic Nephroma

Search Clinical Trials , NIH Clinical Center for Cellular Congenital Mesoblastic Nephroma

Genetic Tests for Cellular Congenital Mesoblastic Nephroma

Anatomical Context for Cellular Congenital Mesoblastic Nephroma

Publications for Cellular Congenital Mesoblastic Nephroma

Articles related to Cellular Congenital Mesoblastic Nephroma:

(show all 20)
# Title Authors PMID Year
1
Renal malignant tumor with the loss of INI1 expression and WT1 positive in a 3-year-old boy: a case report. 61
33209693 2020
2
NTRK-rearranged mesenchymal tumours: diagnostic challenges, morphological patterns and proposed testing algorithm. 61
32278476 2020
3
TRK Fusion Cancers in Children: A Clinical Review and Recommendations for Screening. 61
30592640 2019
4
Cellular Congenital Mesoblastic Nephroma in a Newborn. 61
28770142 2017
5
Cytological diagnosis of mesoblastic nephroma: A report of three cases with summary of prior published cases. 61
27324404 2016
6
Intestinal congenital/infantile fibrosarcoma: a new clinico-pathological entity? 61
25652760 2015
7
Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study. 61
22374738 2012
8
Cellular congenital mesoblastic nephroma: case report. 61
21541470 2011
9
Cytomorphology and morphometry of small round-cell tumors in the region of the kidney. 61
15754373 2005
10
Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. 61
15111298 2004
11
Cellular congenital mesoblastic nephroma with contralateral medullary nephrocalcinosis. 61
15121709 2004
12
Complete response of recurrent cellular congenital mesoblastic nephroma to chemotherapy. 61
12218597 2002
13
Mixed epithelial and stromal tumor of the kidney lacks the genetic alterations of cellular congenital mesoblastic nephroma. 61
11381370 2001
14
Primary synovial sarcoma of the kidney: Report of a case confirmed by molecular detection of the SYT-SSX2 fusion transcripts. 61
11422798 2001
15
Detection of the ETV6-NTRK3 chimeric RNA of infantile fibrosarcoma/cellular congenital mesoblastic nephroma in paraffin-embedded tissue: application to challenging pediatric renal stromal tumors. 61
10658907 2000
16
Ultrastructure of cellular congenital mesoblastic nephroma. 61
8883325 1996
17
Preoperative chemotherapy of cellular congenital mesoblastic nephroma in a 5-month-old infant. 61
1281666 1992
18
Cellular congenital mesoblastic nephroma: what are the options. 61
2545932 1989
19
Two chromosomally different cell populations in a partly cellular congenital mesoblastic nephroma. 61
3030229 1987
20
Cellular congenital mesoblastic nephroma in a newborn. 61
6097889 1984

Variations for Cellular Congenital Mesoblastic Nephroma

Expression for Cellular Congenital Mesoblastic Nephroma

Search GEO for disease gene expression data for Cellular Congenital Mesoblastic Nephroma.

Pathways for Cellular Congenital Mesoblastic Nephroma

Pathways related to Cellular Congenital Mesoblastic Nephroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 YWHAE TLE1
2
Show member pathways
10.61 YWHAE CCNB3
3 9.9 YWHAE CCNB3

GO Terms for Cellular Congenital Mesoblastic Nephroma

Biological processes related to Cellular Congenital Mesoblastic Nephroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of G2/M transition of mitotic cell cycle GO:0010389 8.62 YWHAE CCNB3

Sources for Cellular Congenital Mesoblastic Nephroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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