MCID: CLL010
MIFTS: 25

Cellular Ependymoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cellular Ependymoma

MalaCards integrated aliases for Cellular Ependymoma:

Name: Cellular Ependymoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5500
MeSH 45 D004806
NCIt 51 C4713 C4714
SNOMED-CT 69 57706008
UMLS 74 C1384403

Summaries for Cellular Ependymoma

MalaCards based summary : Cellular Ependymoma is related to clear cell ependymoma and ependymoma. An important gene associated with Cellular Ependymoma is SYP (Synaptophysin), and among its related pathways/superpathways is Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Carboplatin and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include lung, kidney and ovary.

Related Diseases for Cellular Ependymoma

Diseases related to Cellular Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 clear cell ependymoma 32.4 GFAP SYP
2 ependymoma 32.1 GFAP RELA SYP
3 benign ependymoma 30.1 GFAP SYP
4 hydrocephalus 29.7 GFAP SYP
5 ureter small cell carcinoma 10.2 CHGA SYP
6 small cell carcinoma 10.2 CHGA SYP
7 esophageal neuroendocrine tumor 10.2 CHGA SYP
8 neuroendocrine tumor 10.2 CHGA SYP
9 urinary bladder small cell neuroendocrine carcinoma 10.1 CHGA SYP
10 ovarian large-cell neuroendocrine carcinoma 10.1 CHGA SYP
11 auditory system cancer 10.1 CHGA SYP
12 acinar cell cystadenocarcinoma 10.1 CHGA SYP
13 peritoneal serous adenocarcinoma 10.1 CHGA SYP
14 primary hepatic neuroendocrine carcinoma 10.1 CHGA SYP
15 small cell carcinoma of the bladder 10.1 CHGA SYP
16 gastrointestinal neuroendocrine tumor 10.1 CHGA SYP
17 pulmonary large cell neuroendocrine carcinoma 10.1 CHGA SYP
18 large cell neuroendocrine carcinoma 10.1 CHGA SYP
19 gallbladder small cell carcinoma 10.1 CHGA SYP
20 atypical follicular adenoma 10.1 CHGA SYP
21 olfactory groove meningioma 10.1 CHGA SYP
22 cauda equina neoplasm 10.1 CHGA SYP
23 pancreatic serous cystadenoma 10.1 CHGA SYP
24 cystadenoma 10.1 CHGA SYP
25 conventional angiosarcoma 10.1 CHGA SYP
26 olfactory nerve neoplasm 10.1 CHGA SYP
27 autonomic nervous system benign neoplasm 10.1 CHGA SYP
28 nodular ganglioneuroblastoma 10.1 CHGA SYP
29 pulmonary sclerosing hemangioma 10.1 CHGA SYP
30 sclerosing hemangioma 10.1 CHGA SYP
31 hemangioma 10.1 CHGA SYP
32 gastric small cell carcinoma 10.1 CHGA SYP
33 pancreatoblastoma 10.1 CHGA SYP
34 carcinoid tumors, intestinal 10.1 CHGA SYP
35 respiratory system benign neoplasm 10.1 CHGA SYP
36 anterior cranial fossa meningioma 10.1 CHGA SYP
37 gastric squamous cell carcinoma 10.1 CHGA SYP
38 pulmonary blastoma 10.1 CHGA SYP
39 non-functioning pancreatic endocrine tumor 10.1 CHGA SYP
40 carcinoid syndrome 10.1 CHGA SYP
41 cervix small cell carcinoma 10.1 CHGA SYP
42 horseshoe kidney 10.1 CHGA SYP
43 cranial nerve malignant neoplasm 10.1 CHGA SYP
44 granulosa cell tumor of the ovary 10.1 CHGA SYP
45 malignant pheochromocytoma 10.1 CHGA SYP
46 olfactory neuroblastoma 10.1 CHGA SYP
47 gastric tubular adenocarcinoma 10.1 CHGA SYP
48 tubular adenocarcinoma 10.1 CHGA SYP
49 mixed ductal-endocrine carcinoma 10.1 CHGA SYP
50 endocrine organ benign neoplasm 10.1 CHGA SYP

Graphical network of the top 20 diseases related to Cellular Ependymoma:



Diseases related to Cellular Ependymoma

Symptoms & Phenotypes for Cellular Ependymoma

Drugs & Therapeutics for Cellular Ependymoma

Drugs for Cellular Ependymoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 3 41575-94-4 10339178 38904 498142
2
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
3
Etoposide Approved Phase 3 33419-42-0 36462
4
Cisplatin Approved Phase 3 15663-27-1 2767 441203 84093
5
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
6
Emodepside Investigational, Vet_approved Phase 3 155030-63-0
7 Antimitotic Agents Phase 3
8 Antineoplastic Agents, Alkylating Phase 3
9 Immunosuppressive Agents Phase 3
10 Keratolytic Agents Phase 3
11 Dermatologic Agents Phase 3
12 Podophyllotoxin Phase 3 518-28-5
13 Alkylating Agents Phase 3
14 Immunologic Factors Phase 3,Phase 1
15 Antirheumatic Agents Phase 3
16 Etoposide phosphate Phase 3
17 Antineoplastic Agents, Phytogenic Phase 3
18 Topoisomerase Inhibitors Phase 3
19 Vaccines Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Recruiting NCT01096368 Phase 3 Carboplatin;Cisplatin;Cyclophosphamide;Etoposide;Vincristine Sulfate Liposome
2 Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine Recruiting NCT02722512 Phase 1

Search NIH Clinical Center for Cellular Ependymoma

Genetic Tests for Cellular Ependymoma

Anatomical Context for Cellular Ependymoma

MalaCards organs/tissues related to Cellular Ependymoma:

42
Lung, Kidney, Ovary, Pituitary, Cervix, Pineal

Publications for Cellular Ependymoma

Articles related to Cellular Ependymoma:

# Title Authors Year
1
Infantile holocord cellular ependymoma with communicating hydrocephalus: unusual presentation of a rare case. ( 23512254 )
2014
2
Mucin-secreting cellular ependymoma: a light and electron microscopy study. ( 10582269 )
1999
3
Malignant primitive neuroepithelial tumour of soft tissues mimicking a cellular ependymoma. ( 1495851 )
1992

Variations for Cellular Ependymoma

Expression for Cellular Ependymoma

Search GEO for disease gene expression data for Cellular Ependymoma.

Pathways for Cellular Ependymoma

Pathways related to Cellular Ependymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.52 GFAP SYP

GO Terms for Cellular Ependymoma

Molecular functions related to Cellular Ependymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 GFAP RELA SYP

Sources for Cellular Ependymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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