MCID: CLL006
MIFTS: 21

Cellular Neurofibroma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cellular Neurofibroma

MalaCards integrated aliases for Cellular Neurofibroma:

Name: Cellular Neurofibroma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5152
NCIt 50 C41427
UMLS 70 C1516371

Summaries for Cellular Neurofibroma

MalaCards based summary : Cellular Neurofibroma is related to neurofibroma and optic nerve astrocytoma. An important gene associated with Cellular Neurofibroma is NF1 (Neurofibromin 1). Affiliated tissues include spinal cord, skeletal muscle and kidney, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Cellular Neurofibroma

Diseases related to Cellular Neurofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 neurofibroma 30.4 SOX10 NF1
2 optic nerve astrocytoma 10.1 SMARCB1 NF1
3 peripheral nerve schwannoma 10.1 SMARCB1 NF1
4 malignant spindle cell melanoma 10.1 SOX10 NF1
5 optic nerve sheath meningioma 10.1 SMARCB1 NF1
6 schwannoma of twelfth cranial nerve 10.1 SMARCB1 NF1
7 hypoglossal nerve disease 10.1 SMARCB1 NF1
8 neurofibrosarcoma 10.1 SOX10 NF1
9 optic nerve neoplasm 10.1 SMARCB1 NF1
10 corpus callosum lipoma 10.1 SMARCB1 NF1
11 cerebral hemisphere lipoma 10.1 SMARCB1 NF1
12 spinal canal and spinal cord meningioma 10.1 SMARCB1 NF1
13 spinal meningioma 10.1 SMARCB1 NF1
14 cranial nerve neoplasm 10.0 SMARCB1 NF1
15 spinal cancer 10.0 SMARCB1 NF1
16 epithelioid neurofibroma 10.0 NF1 B3GAT1
17 adult malignant schwannoma 10.0 NF1 B3GAT1
18 plexiform neurofibroma 10.0 SUZ12 NF1
19 sweat gland benign neoplasm 10.0 SOX10 SMARCB1
20 gliofibroma 10.0 NF1 B3GAT1
21 ganglioglioma 10.0 SMARCB1 NF1
22 skeletal muscle cancer 10.0 SMARCB1 NF1
23 muscle cancer 10.0 SMARCB1 NF1
24 neuroma 10.0 SMARCB1 NF1
25 infratentorial cancer 9.9 SMARCB1 NF1
26 subungual glomus tumor 9.9 TLE1 NF1
27 pilocytic astrocytoma 9.9 SOX10 NF1
28 basal cell nevus syndrome 9.9 SMARCB1 NF1
29 sarcoma 9.9
30 spindle cell sarcoma 9.9
31 neurofibromatosis 9.9
32 plexiform schwannoma 9.8 SOX10 SMARCB1 NF1
33 atypical neurofibroma 9.8 SUZ12 SOX10 NF1
34 cellular schwannoma 9.8 SOX10 SMARCB1 NF1
35 neurilemmoma 9.8 SOX10 SMARCB1 NF1
36 melanoma, cutaneous malignant 1 9.8 SOX10 NF1
37 neurilemmomatosis 9.8 SOX10 SMARCB1 NF1
38 kidney clear cell sarcoma 9.8 TLE1 SMARCB1
39 synovium cancer 9.8 TLE1 SMARCB1
40 meningioma, familial 9.8 SOX10 SMARCB1 NF1
41 li-fraumeni syndrome 9.7 SMARCB1 NF1
42 atypical teratoid rhabdoid tumor 9.7 TLE1 SMARCB1
43 gastrointestinal stromal tumor 9.7 SMARCB1 NF1 B3GAT1
44 sarcoma, synovial 9.6 TLE1 SMARCB1 NF1
45 chondrosarcoma, extraskeletal myxoid 9.6 TLE1 SOX10 SMARCB1
46 malignant triton tumor 9.6 TLE1 NF1 B3GAT1
47 malignant glandular tumor of peripheral nerve sheath 9.5 TLE1 SMARCB1 B3GAT1
48 epithelioid malignant peripheral nerve sheath tumor 9.4 TLE1 SOX10 SMARCB1 NF1
49 malignant peripheral nerve sheath tumor 9.1 TLE1 SOX10 SMARCB1 NF1 B3GAT1

Graphical network of the top 20 diseases related to Cellular Neurofibroma:



Diseases related to Cellular Neurofibroma

Symptoms & Phenotypes for Cellular Neurofibroma

GenomeRNAi Phenotypes related to Cellular Neurofibroma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 10.1 NF1 SMARCB1 SUZ12
2 Decreased viability GR00221-A-2 10.1 NF1 SMARCB1 SUZ12
3 Decreased viability GR00221-A-3 10.1 SMARCB1
4 Decreased viability GR00221-A-4 10.1 NF1
5 Decreased viability GR00249-S 10.1 NF1 SMARCB1 SUZ12
6 Decreased viability GR00381-A-1 10.1 SMARCB1
7 Decreased viability GR00386-A-1 10.1 NF1 SUZ12
8 shRNA abundance <= 50% GR00343-S 8.92 NF1 SMARCB1 SOX10 SUZ12

MGI Mouse Phenotypes related to Cellular Neurofibroma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.63 B3GAT1 NF1 SMARCB1 SOX10 SUZ12 TLE1
2 neoplasm MP:0002006 9.26 NF1 SMARCB1 SOX10 SUZ12
3 pigmentation MP:0001186 8.8 NF1 SOX10 SUZ12

Drugs & Therapeutics for Cellular Neurofibroma

Search Clinical Trials , NIH Clinical Center for Cellular Neurofibroma

Genetic Tests for Cellular Neurofibroma

Anatomical Context for Cellular Neurofibroma

MalaCards organs/tissues related to Cellular Neurofibroma:

40
Spinal Cord, Skeletal Muscle, Kidney

Publications for Cellular Neurofibroma

Articles related to Cellular Neurofibroma:

# Title Authors PMID Year
1
Dermatofibrosarcoma protuberans of the vulva: a clinicopathologic and immunohistochemical study of 13 cases. 61
20139758 2010
2
Tumour and tumour-like conditions of peripheral nerve origin: ten years' experience. 61
21209517 2010
3
Cellular neurofibroma with atypia mimics sarcoma: report of a case with immunohistochemical staining pattern analysis and literature review. 61
17098683 2006
4
A case of episcleral cellular neurofibroma. 61
17318327 2005
5
Neurofibroma and cellular neurofibroma with atypia: a report of 14 tumors. 61
10478679 1999
6
Neurofibroma and cellular neurofibroma with atypia: a report of 14 tumors. 61
9414187 1997

Variations for Cellular Neurofibroma

Expression for Cellular Neurofibroma

Search GEO for disease gene expression data for Cellular Neurofibroma.

Pathways for Cellular Neurofibroma

GO Terms for Cellular Neurofibroma

Biological processes related to Cellular Neurofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 spinal cord development GO:0021510 8.96 SUZ12 NF1
2 peripheral nervous system development GO:0007422 8.62 SOX10 NF1

Sources for Cellular Neurofibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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