MCID: CLL001
MIFTS: 29

Cellular Schwannoma

Categories: Cancer diseases, Neuronal diseases
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Aliases & Classifications for Cellular Schwannoma

MalaCards integrated aliases for Cellular Schwannoma:

Name: Cellular Schwannoma 11 5 14 71
Cellular Neurinoma 11

Classifications:



External Ids:

Disease Ontology 11 DOID:3196
NCIt 49 C4724
SNOMED-CT 68 253086004
UMLS 71 C0431124

Summaries for Cellular Schwannoma

Disease Ontology: 11 A neurilemmoma with a predominantly cellular growth but no Verocay bodies.

MalaCards based summary: Cellular Schwannoma, also known as cellular neurinoma, is related to cerebellopontine angle tumor and malignant peripheral nerve sheath tumor. An important gene associated with Cellular Schwannoma is SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1). Affiliated tissues include trigeminal ganglion, adrenal gland and skin, and related phenotypes are Increased proliferation and neoplasm

Related Diseases for Cellular Schwannoma

Diseases related to Cellular Schwannoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 299)
# Related Disease Score Top Affiliating Genes
1 cerebellopontine angle tumor 30.1 SMARCB1 NF2
2 malignant peripheral nerve sheath tumor 30.0 SOX10 NF2 NF1 KIT CD34
3 cutaneous fibrous histiocytoma 29.9 SOX10 CD34
4 neurofibromatosis 29.9 SMARCB1 NF2 NF1 KIT
5 neurilemmoma 29.9 SOX10 SMARCB1 NF2 NF1 KIT CD34
6 acoustic neuroma 29.8 SMARCB1 NF2 NF1
7 perineurioma 29.7 NF2 KIT CD34
8 sarcoma 29.6 SSX1 SS18 SMARCB1 KIT
9 hemangiopericytoma, malignant 29.6 SSX1 KIT CD34
10 smooth muscle tumor 29.5 KIT CD34 ANO1
11 neurofibroma 29.4 SOX10 NF2 NF1 KIT CD34
12 neurilemmomatosis 29.3 SS18 SOX10 SMARCB1 NF2 NF1
13 plexiform neurofibroma 29.2 SOX10 SMARCB1 NF2 NF1 KIT
14 neurofibromatosis, type i 29.2 NF2 NF1 KIT CD34 ANO1
15 plexiform schwannoma 28.5 SOX10 SMARCB1 NF2 NF1 KIT CD34
16 full schwannomatosis 10.3 SMARCB1 NF2
17 posterior pituitary gland neoplasm 10.3 SMARCB1 NF2
18 central nervous system angiosarcoma 10.3 SMARCB1 CD34
19 childhood meningioma 10.3 SMARCB1 NF2
20 pineal region meningioma 10.3 SMARCB1 NF2
21 cerebral falx meningioma 10.3 SMARCB1 NF2
22 parasagittal meningioma 10.3 SMARCB1 NF2
23 cerebral convexity meningioma 10.3 SMARCB1 NF2
24 schwannomatosis 1 10.3 SMARCB1 NF2
25 olfactory groove meningioma 10.3 SMARCB1 NF2
26 anterior cranial fossa meningioma 10.3 SMARCB1 NF2
27 parietal lobe neoplasm 10.3 SMARCB1 CD34
28 proliferative fasciitis 10.3 SMARCB1 CD34
29 brain meningioma 10.3 SMARCB1 NF2
30 transitional meningioma 10.3 SMARCB1 NF2
31 vulvar sarcoma 10.3 SMARCB1 CD34
32 central nervous system fibrosarcoma 10.3 NF2 CD34
33 secretory meningioma 10.3 SMARCB1 NF2
34 lung meningioma 10.3 NF2 CD34
35 rhabdoid meningioma 10.2 SMARCB1 NF2
36 skull base meningioma 10.2 SMARCB1 NF2
37 lipofibromatosis-like neural tumor 10.2 SOX10 CD34
38 psammomatous meningioma 10.2 NF2 CD34
39 histiocytoid hemangioma 10.2 SMARCB1 CD34
40 meninges hemangiopericytoma 10.2 NF2 CD34
41 meningothelial meningioma 10.2 SMARCB1 NF2
42 optic nerve astrocytoma 10.2 SMARCB1 NF1
43 angiomatous meningioma 10.2 NF2 CD34
44 spinal cord ependymoma 10.2 SMARCB1 NF2
45 skull base cancer 10.2 SMARCB1 NF2
46 congenital granular cell tumor 10.2 SOX10 CD34
47 central epithelioid sarcoma 10.2 SMARCB1 CD34
48 vulvar proximal-type epithelioid sarcoma 10.2 SMARCB1 CD34
49 capillary lymphangioma 10.2 SOX10 CD34
50 pacinian tumor 10.2 NF1 CD34

Graphical network of the top 20 diseases related to Cellular Schwannoma:



Diseases related to Cellular Schwannoma

Symptoms & Phenotypes for Cellular Schwannoma

GenomeRNAi Phenotypes related to Cellular Schwannoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Cellular Schwannoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.63 CD34 KIT NF1 NF2 SMARCB1 SOX10
2 pigmentation MP:0001186 9.56 KIT NF1 NF2 SOX10
3 digestive/alimentary MP:0005381 9.43 ANO1 KIT NF1 NF2 SMARCB1 SOX10
4 integument MP:0010771 9.17 ANO1 CD34 KIT NF1 NF2 SMARCB1

Drugs & Therapeutics for Cellular Schwannoma

Search Clinical Trials, NIH Clinical Center for Cellular Schwannoma

Genetic Tests for Cellular Schwannoma

Anatomical Context for Cellular Schwannoma

Organs/tissues related to Cellular Schwannoma:

MalaCards : Trigeminal Ganglion, Adrenal Gland, Skin, Kidney, Tongue, Pituitary, Lung

Publications for Cellular Schwannoma

Articles related to Cellular Schwannoma:

(show top 50) (show all 126)
# Title Authors PMID Year
1
FDG PET/CT in a Case With Cellular Schwannoma of the Kidney. 62
35619199 2022
2
Plexiform Cellular Schwannoma in Infancy and Childhood: A Clinicopathological Study of Seven Cases of an Underrecognized Nerve Sheath Tumor with a Tendency Toward Local Recurrence. 62
34696615 2022
3
A Rare Case of an Adrenal Mass Proved to Be a Benign Cellular Schwannoma. 62
35464584 2022
4
Vestibular Schwannomas in Young Patients: A 12-Year Experience in a Single Center. 62
34710579 2022
5
Orbito-cranial schwannoma-a multicentre experience. 62
34999720 2022
6
Comparison of pathological, radiological, and prognostic features between cellular schwannoma and non-cellular schwannoma. 62
34049057 2021
7
Paraspinal plexiform schwannoma of unknown nerve origin: A case report. 62
33486308 2021
8
Tongue Schwannoma: A Clinicopathologic Study of 19 Cases. 62
31485983 2020
9
Intracranial cellular schwannomas: a clinicopathological study of 20 cases. 62
31379028 2020
10
Successful Excision of Endobronchial Cellular Schwannoma With Right Lower Sleeve Lobectomy. 62
30205116 2019
11
MR imaging of vaginal cellular schwannoma. 62
30195699 2019
12
CHD4 as a Potential Biomarker in Differentiating Between Cellular Schwannoma and Malignant Peripheral Nerve Sheath Tumor. 62
28549031 2018
13
Expression of PAX3 Distinguishes Biphenotypic Sinonasal Sarcoma From Histologic Mimics. 62
29863547 2018
14
Spinal cellular schwannoma: An analysis of imaging manifestation and clinicopathological findings. 62
30017303 2018
15
Large retroperitoneal schwannoma: a rare cause of chronic back pain. 62
29896991 2018
16
Unusual presentation of retroperitoneal Schwannoma: case report. 62
29442061 2017
17
TFG-MET fusion in an infantile spindle cell sarcoma with neural features. 62
28510278 2017
18
Selected benign cutaneous lesions that may simulate melanoma histologically. 62
27221234 2016
19
Methylation-based classification of benign and malignant peripheral nerve sheath tumors. 62
26857854 2016
20
Cutaneous Cellular Pseudoglandular Schwannoma: An Unusual Histopathologic Variant. 62
26844614 2016
21
Loss of H3K27 trimethylation distinguishes malignant peripheral nerve sheath tumors from histologic mimics. 62
26585554 2016
22
Spontaneous acute hemorrhage of intraspinal canal cellular schwannoma with paraplegia: A case report. 62
25488387 2015
23
Cellular schwannoma of the retroperitoneum with cystic degeneration, mimicking an ovarian cyst, with CKAE1/AE3 and desmin expression. 62
25180931 2015
24
Morphologic and immunohistochemical features of malignant peripheral nerve sheath tumors and cellular schwannomas. 62
25189642 2015
25
[One case of nasal cellular schwannoma]. 62
25598379 2014
26
A recurrent cellular schwannoma. 62
25346907 2014
27
Atypical presentation of sinonasal cellular schwannoma: a nonsolitary mass with osseous, orbital, and intracranial invasion. 62
25083375 2014
28
Primary pleural hybrid cellular schwannoma/perineurioma: a case report. 62
24998375 2014
29
Large Vestibular Schwannomas Presenting during Pregnancy: Management Strategies. 62
25072015 2014
30
Infantile cellular schwannoma developing on the skin with atypical clinical features. 62
25232315 2014
31
An unusual location for cellular schwannoma. 62
24718004 2014
32
Cellular schwannoma arising from the gastric wall misdiagnosed as a gastric stromal tumor: A case report. 62
24396458 2014
33
Conventional spindle cell-type malignant peripheral nerve sheath tumor arising in a sporadic schwannoma. 62
24007690 2013
34
Cellular schwannoma arising from sigmoid mesocolon presenting as torsion. 62
24349845 2013
35
Giant invasive sacral schwannoma showing chromosomal numerical aberrations [-14,+18,+22]. 62
24066220 2013
36
Cellular schwannoma masquerading as malignant peripheral nerve sheath tumour: a diagnostic dilemma. 62
23709140 2013
37
Combined craniofacial approach for the removal of a large trigeminal schwannoma invading the infratemporal fossa. 62
21842149 2012
38
A spinal epidural dumbbell cellular schwannoma in an infant. 62
22325076 2012
39
Clinicopathologic and molecular analysis of a choroidal pigmented schwannoma in the context of a PTEN hamartoma tumor syndrome. 62
22281088 2012
40
Resection of perihilar biliary schwannoma. 62
21665464 2011
41
[A 33 year old woman with a six-year history of slight thoracic-abdominal pain]. 62
21527973 2011
42
Low-back pain as the presenting sign in a patient with a giant, sacral cellular schwannoma: 10-year follow-up. 62
21214314 2011
43
Trisomy 17 in congenital plexiform (multinodular) cellular schwannoma. 62
21156251 2010
44
Intrapulmonary cellular schwannoma. 62
20868846 2010
45
Giant schwannoma of the lumbar spine. A case report. 62
20358489 2010
46
Meningothelial-like whorls in a retroperitoneal cellular schwannoma: potential diagnostic pitfall. 62
20055955 2010
47
Non-healing ulcer on the great toe due to cellular schwannoma. 62
20055863 2009
48
Primary intraventricular schwannomas. 62
19632768 2009
49
Cellular schwannoma of the abducens nerve: case report and review of the literature. 62
19200646 2009
50
Retroperitoneal schwannoma mimicking uterine myoma. 62
19574183 2009

Variations for Cellular Schwannoma

ClinVar genetic disease variations for Cellular Schwannoma:

5
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 SMARCB1 NM_003073.5(SMARCB1):c.*82C>T SNV Pathogenic
239481 rs878854600 GRCh37: 22:24176449-24176449
GRCh38: 22:23834262-23834262

Expression for Cellular Schwannoma

Search GEO for disease gene expression data for Cellular Schwannoma.

Pathways for Cellular Schwannoma

GO Terms for Cellular Schwannoma

Cellular components related to Cellular Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 npBAF complex GO:0071564 8.92 SS18 SMARCB1

Biological processes related to Cellular Schwannoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mast cell proliferation GO:0070662 9.46 NF1 KIT
2 Schwann cell proliferation GO:0014010 9.26 NF2 NF1
3 negative regulation of Schwann cell proliferation GO:0010626 9.1 SOX10 NF2 NF1

Sources for Cellular Schwannoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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