Cellulitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: CLL003 MIFTS: 59	Cellulitis Categories: Immune diseases, Skin diseases
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Aliases & Classifications for Cellulitis

MalaCards integrated aliases for Cellulitis:

Name: Cellulitis ¹² ²⁹ ⁵⁵ ⁴³ ⁴⁴ ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Skin diseases Immune diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the skin and subcutaneous tissue

Infections of the skin and subcutaneous tissue

Cellulitis

Cellulitis, unspecified

External Ids:

Disease Ontology ¹² DOID:3488

ICD10 ³³ L03.90 L03 L03.9

MeSH ⁴⁴ D002481

NCIt ⁵⁰ C26715 C34454

SNOMED-CT ⁶⁸ 62837005 74276003

UMLS ⁷³ C0007642 C0007646

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Summaries for Cellulitis

MedlinePlus : ⁴³ Cellulitis is an infection of the skin and deep underlying tissues. Group A strep (streptococcal) bacteria are the most common cause. The bacteria enter your body when you get an injury such as a bruise, burn, surgical cut, or wound. Symptoms include Fever and chills Swollen glands or lymph nodes A rash with painful, red, tender skin. The skin may blister and scab over. Your health care provider may take a sample or culture from your skin or do a blood test to identify the bacteria causing infection. Treatment is with antibiotics. They may be oral in mild cases, or intravenous (by IV) for more severe cases. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Cellulitis is related to wells syndrome and scleritis, and has symptoms including fever, pruritus and exanthema. An important gene associated with Cellulitis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and Developmental Biology. The drugs Lincomycin and Clindamycin have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and breast, and related phenotypes are cellular and growth/size/body region

Disease Ontology : ¹² A skin disease where there is a diffuse infection of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin. Cellulitis can be caused by normal skin flora or by exogenous bacteria, and often occurs where the skin has previously been broken

Wikipedia : ⁷⁶ Cellulitis is a bacterial infection involving the inner layers of the skin. It specifically affects the... more...

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Related Diseases for Cellulitis

Diseases related to Cellulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 402)

#	Related Disease	Score	Top Affiliating Genes
1	wells syndrome	33.1	IL1R1 IL5 RNASE3
2	scleritis	30.1	IL5 TNF
3	pyoderma	29.9	DSG1 IL1R1 TNF
4	churg-strauss syndrome	29.7	IL5 RNASE3 TNF
5	keratoconjunctivitis	29.6	IL5 RNASE3 TNF
6	bronchiolitis	29.6	IL5 RNASE3 TNF
7	autoimmune disease	29.5	COL17A1 DSG1 IL5 TNF
8	keratosis	29.3	ATP2A2 DSG1 DSP
9	chronic granulomatous disease	29.2	CYBA CYBB NCF1 NCF2
10	pemphigus foliaceus	29.1	DSG1 DSG3 DST PPL
11	pemphigus vulgaris	28.6	DSC3 DSG1 DSG3 DSP DST PPL
12	pemphigus	28.6	ATP2C1 COL17A1 DSC3 DSG1 DSG3 DSP
13	bullous pemphigoid	28.3	COL17A1 DSG1 DSG3 DSP DST IL5
14	skin disease	27.7	ATP2A2 ATP2C1 COL17A1 DSC3 DSG1 DSG3
15	orbital cellulitis	12.5
16	perifolliculitis capitis abscedens et suffodiens, familial	12.1
17	tinea unguium	11.9
18	ludwig's angina	11.8
19	parametritis	11.4
20	erysipelas	11.4
21	lacrimal duct defect	11.3
22	erysipeloid	11.3
23	nocardiosis	11.3
24	lymphedema, hereditary, ia	11.0
25	lymphedema, hereditary, ii	11.0
26	whim syndrome	11.0
27	fusariosis	11.0
28	clear cell acanthoma	11.0
29	elizabethkingia anophelis infection	11.0
30	sinusitis	10.3
31	thrombosis	10.3
32	angioimmunoblastic lymphadenopathy with dysproteinemia	10.3	IL5 TNF
33	loeffler endocarditis	10.3	IL5 RNASE3
34	lichen planus pemphigoides	10.2	COL17A1 DST
35	lymphoma	10.2
36	vulvar vestibulitis syndrome	10.2	IL1R1 TNF
37	paronychia	10.2
38	cow milk allergy	10.2	IL5 RNASE3 TNF
39	paragonimiasis	10.2	IL5 RNASE3
40	erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige	10.2	DSG1 DSP
41	linear iga disease	10.2	COL17A1 DST
42	conjunctival disease	10.2	IL5 RNASE3 TNF
43	cough variant asthma	10.2	IL5 RNASE3
44	neurotic excoriation	10.2	COL17A1 DST
45	common cold	10.2	IL1R1 IL5 RNASE3
46	nose disease	10.2	IL5 RNASE3 TNF
47	cold urticaria	10.2	IL1R1 RNASE3
48	parasitic helminthiasis infectious disease	10.2	IL5 RNASE3 TNF
49	pemphigoid gestationis	10.2	COL17A1 DST IL5
50	upper respiratory tract disease	10.2	IL5 RNASE3 TNF

Graphical network of the top 20 diseases related to Cellulitis:

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Symptoms & Phenotypes for Cellulitis

UMLS symptoms related to Cellulitis:

fever, pruritus, exanthema

MGI Mouse Phenotypes related to Cellulitis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cellular	MP:0005384	10.17	ATP2A2 ATP2C1 CYBA CYBB DSC3 DSG3
2	growth/size/body region	MP:0005378	10.11	ATP2A2 ATP2C1 CYBB DSG1 DSG3 DSP
3	digestive/alimentary	MP:0005381	10.06	ATP2A2 CYBA CYBB DSG3 DSP IL5
4	hematopoietic system	MP:0005397	10.06	ATP2A2 CDH17 CYBA CYBB DSG3 IL1R1
5	immune system	MP:0005387	10	ATP2A2 CDH17 CYBA CYBB DSG3 IL1R1
6	adipose tissue	MP:0005375	9.93	CYBA CYBB DSG1 DSG3 IL1R1 TNF
7	integument	MP:0010771	9.85	ATP2A2 ATP2C1 DSC3 DSG1 DSG3 DSP
8	neoplasm	MP:0002006	9.43	ATP2A2 ATP2C1 CYBB IL1R1 IL5 TNF
9	respiratory system	MP:0005388	9.28	ATP2A2 CYBA DSG3 IL1R1 IL5 LAMA3

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Drugs & Therapeutics for Cellulitis

Drugs for Cellulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 386)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Lincomycin

Approved, Vet_approved

Phase 4

154-21-2

656509

Clindamycin

Approved, Vet_approved

Phase 4,Phase 2,Phase 3,Not Applicable

18323-44-9

29029

Permethrin

Approved, Investigational

Phase 4,Not Applicable

52645-53-1

40326

Mupirocin

Approved, Investigational, Vet_approved

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

12650-69-0

446596

Cefazolin

Approved

Phase 4,Phase 3,Phase 2,Not Applicable

25953-19-9

656510 33255

Penicillin V

Approved, Vet_approved

Phase 4

87-08-1

6869

Vancomycin

Approved

Phase 4,Phase 2,Phase 3

1404-90-6

14969 441141

Daptomycin

Approved, Investigational

Phase 4,Phase 3,Phase 2

103060-53-3

16129629

Oxacillin

Approved, Investigational

Phase 4,Phase 3,Phase 2

66-79-5

6196

Cephalexin

Approved, Investigational, Vet_approved

Phase 4,Phase 2,Phase 3,Not Applicable

15686-71-2

27447

Sulbactam

Approved

Phase 4

68373-14-8

Amoxicillin

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Not Applicable

26787-78-0

33613

Teicoplanin

Approved, Investigational

Phase 4,Phase 3

61036-62-2

Minocycline

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

10118-90-8

5281021

Tigecycline

Approved

Phase 4,Phase 3,Phase 2

220620-09-7

5282044

Sultamicillin

Approved, Investigational

Phase 4

76497-13-7

Ampicillin

Approved, Vet_approved

Phase 4

69-53-4

6249

Cefdinir

Approved

Phase 4

91832-40-5

6915944

Warfarin

Approved

Phase 4

81-81-2

6691 54678486

Oritavancin

Approved, Investigational

Phase 4,Phase 3,Phase 2

171099-57-3

16129632

Tacrolimus

Approved, Investigational

Phase 4

104987-11-3

445643 439492

Pimecrolimus

Approved, Investigational

Phase 4

137071-32-0

6447131 17753757

Chlorhexidine

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Not Applicable

55-56-1

2713 9552079

Ivermectin

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

70288-86-7

6474909

Azithromycin

Approved

Phase 4,Phase 3,Not Applicable

83905-01-5

55185 447043

Conivaptan

Approved, Investigational

Phase 4

210101-16-9

151171

Fondaparinux

Approved, Investigational

Phase 4

104993-28-4

Cloxacillin

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2

61-72-3

6098

Nafcillin

Approved, Investigational

Phase 4,Phase 2

985-16-0, 147-52-4

8982

Thrombin

Approved, Investigational

Phase 4

Petrolatum

Approved, Investigational

Phase 4,Phase 2,Phase 1,Not Applicable

8009-03-8

Dalbavancin

Approved, Investigational

Phase 4,Phase 3

91097-81-3, 171500-79-1

122186

Fusidic Acid

Approved, Investigational

Phase 4,Phase 3,Phase 2,Not Applicable

6990-06-3

3000226

Bacitracin

Approved, Vet_approved

Phase 4

1405-87-4

10909430 439542

Lenograstim

Approved, Investigational

Phase 4

135968-09-1

Pentoxifylline

Approved, Investigational

Phase 4

6493-05-6

4740

Acetylcysteine

Approved, Investigational

Phase 4

616-91-1

12035

Serine

Approved, Nutraceutical

Phase 4

56-45-1

5951

Clindamycin palmitate

Phase 4,Phase 2,Phase 3,Not Applicable

Anti-Bacterial Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Clindamycin phosphate

Phase 4,Phase 2,Phase 3,Not Applicable

Floxacillin

Phase 4,Phase 3,Not Applicable

Anti-Infective Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Antibiotics, Antitubercular

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

methicillin

Phase 4,Phase 3,Phase 2,Not Applicable

Analgesics

Phase 4,Phase 2,Phase 3,Not Applicable

Antirheumatic Agents

Phase 4,Phase 3,Phase 2

Dermatologic Agents

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Peripheral Nervous System Agents

Phase 4,Phase 2,Phase 3,Not Applicable

Expectorants

Phase 4,Phase 2,Phase 3

Interventional clinical trials:

(show top 50) (show all 400)

#	Name	Status	NCT ID	Phase	Drugs
1	Adjunctive Clindamycin for Cellulitis: C4C Trial.	Unknown status	NCT01876628	Phase 4	Flucloxacillin and Clindamycin;Flucloxacillin and placebo
2	RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg	Completed	NCT00552799	Phase 4	Penicillin VK
3	Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas	Completed	NCT00295178	Phase 4	Daptomycin;Vancomycin
4	The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin	Completed	NCT01626560	Phase 4	Daptomycin;Vancomycin
5	Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections	Completed	NCT01549613	Phase 4	Daptomycin;Vancomycin
6	Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections.	Completed	NCT00555061	Phase 4	Retapamulin Ointment, 1%
7	Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA	Completed	NCT01419184	Phase 4	Daptomycin;Vancomycin
8	Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections	Completed	NCT00352612	Phase 4	clindamycin;cephalexin
9	Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections	Completed	NCT00368537	Phase 4	Tigecycline;ampicillin-sulbactam
10	A Study to Compare Cefdinir and Cephalexin for the Treatment of Mild to Moderate Uncomplicated Skin Infections	Completed	NCT00234949	Phase 4	cefdinir;cephalexin
11	Safety and Efficacy Study of Altabax Ointment in the Treatment of Secondarily Infected Atopic Dermatitis	Completed	NCT01064947	Phase 4	Retapamulin 1%
12	Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA	Completed	NCT02582203	Phase 4	Ceftaroline;Vancomycin
13	Study of Wound Packing After Superficial Skin Abscess Drainage	Completed	NCT00746109	Phase 4
14	A Study to Evaluate the Safety of a Single IV Dose of Orbactiv (Oritavancin) in Subjects on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)	Completed	NCT02452918	Phase 4	Oritavancin
15	Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial	Completed	NCT00799292	Phase 4	Vasopressin
16	Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis	Completed	NCT00121381	Phase 4	Pimecrolimus plus topical corticosteroid (TCS);Pimecrolimus vehicle (Placebo) plus topical corticosteroid (TCS)
17	Effect of Chlorhexidine Skin Cleansing on Skin Flora	Completed	NCT00198679	Phase 4	Chlorhexidine
18	Azithromycin - Ivermectin Mass Drug Administration for Skin Disease	Completed	NCT02775617	Phase 4	Ivermectin;Azithromycin;Permethrin
19	Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions	Completed	NCT02137447	Phase 4
20	Appendicectomy Skin Closure Technique: Changing Paradigms (ASC)	Completed	NCT02625987	Phase 4
21	A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia	Completed	NCT00435591	Phase 4	Conivaptan;placebo
22	World-wide Randomized Antibiotic Envelope Infection Prevention Trial	Completed	NCT02277990	Phase 4
23	The Effects of Arixtra on Wound Drainage Following Total Joint Arthroplasty	Completed	NCT00909064	Phase 4	Fondaparinux Sodium (Arixtra)
24	Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure Infections	Completed	NCT00711802	Phase 4	Daptomycin;Standard of Care (SOC)
25	Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty	Completed	NCT01410240	Phase 4	FLOSEAL Hemostatic Matrix + Standard of care
26	Topical Therapy for Prevention of Infections in Preterm Infants	Completed	NCT00162747	Phase 4	Aquaphor;Sunflower Seed Oil
27	Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection	Completed	NCT01126268	Phase 4	Retapamulin (Altabax)
28	Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence	Recruiting	NCT02566928	Phase 4	2% mupirocin ointment
29	GCSF in Alcoholic Hepatitis	Recruiting	NCT03703674	Phase 4	GCSF
30	G-CSF Plus NAC In Severe Alcoholic Hepatitis	Recruiting	NCT02971306	Phase 4	standard medical therapy;G-CSF;n-Acetylcysteine
31	Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections	Recruiting	NCT03426761	Phase 4	Dalbavancin;Vancomycin
32	Group A Pharyngitis in Children: The GASPARD Study	Recruiting	NCT03264911	Phase 4	Amoxicillin or Placebo
33	Penicillin for the Emergency Department Outpatient Treatment of CELLulitis	Not yet recruiting	NCT02922686	Phase 4	Flucloxacillin;Phenoxymethylpenicillin;Placebo (for phenoxymethylpenicillin)
34	Hospital Avoidance Strategies for ABSSSI	Not yet recruiting	NCT03372941	Phase 4	Dalbavancin
35	Duration of ANtibiotic Therapy for CEllulitis	Terminated	NCT02032654	Phase 4	Flucloxacillin;Placebo (for flucloxacillin)
36	Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure Infections	Terminated	NCT00463801	Phase 4	Daptomycin
37	Silver Impregnated Dressings to Reduce Wound Complications in Obese Patients at Cesarean Section	Terminated	NCT01528696	Phase 4
38	Local Application of Vancomycin Powder in Grade I-IIIA Open Fractures	Terminated	NCT02400112	Phase 4	Vancomycin
39	Fucidin® Cream in the Treatment of Impetigo	Terminated	NCT00986856	Phase 4	Fucidin® cream
40	Use of Santyl Within an Accountable Care Organization	Withdrawn	NCT02716519	Phase 4
41	Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department	Unknown status	NCT00323219	Phase 3	Cefazolin and Moxifloxacin
42	Citriodiol® and Impetigo	Unknown status	NCT01611909	Phase 2, Phase 3	p-menthane-3,8-diol oil
43	A Randomized Clinical Trial to Prevent Recurrent CA-MRSA Infection	Completed	NCT00560599	Phase 3	mupirocin and chlorhexidine;mupirocin, chlorhexidine, & household cleaning/disinfection
44	Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Skin Infections	Completed	NCT01400867	Phase 2, Phase 3	Ceftaroline fosamil;Vancomycin +/- Aztreonam or Cefazolin +/- Aztreonam;Cephalexin or Clindamycin or Linezolid
45	Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections	Completed	NCT00424190	Phase 3	IV Vancomycin plus IV Aztreonam;Ceftaroline
46	Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections	Completed	NCT00423657	Phase 3	ceftaroline;vancomycin plus aztreonam;Placebo
47	Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA	Completed	NCT00852540	Phase 3	Retpamulin Ointment, 1%;Linezolid
48	Retapamulin Versus Placebo in Secondarily-Infected Traumatic Lesions (SITL)	Completed	NCT00684177	Phase 3	Retapamulin Ointment, 1%;Placebo ointment
49	A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections	Completed	NCT00249197	Phase 3	levofloxacin
50	China Registration Study in Patients With Skin Infections	Completed	NCT00772447	Phase 3	Daptomycin;Vancomycin

Search NIH Clinical Center for Cellulitis

Cochrane evidence based reviews: cellulitis

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Genetic Tests for Cellulitis

Genetic tests related to Cellulitis:

#	Genetic test	Affiliating Genes
1	Cellulitis ²⁹

Sources

Anatomical Context for Cellulitis

MalaCards organs/tissues related to Cellulitis:

⁴¹

Skin, Testes, Breast, Lymph Node, T Cells, Colon, Kidney

Sources

Publications for Cellulitis

Articles related to Cellulitis:

(show top 50) (show all 1584)

#	Title	Authors	Year
1	Systemic corticosteroids may be beneficial for managing severe or refractory orbital cellulitis in children. ( 29920768 )	Brameli A....Scheuerman O.	2018
2	Non-invasive assessment of cellulitis from snapshot hyperspectral imaging - A primary study. ( 29368433 )	Chen Y.M....Lui P.W.	2018
3	Indicators for imaging in periorbital cellulitis secondary to rhinosinusitis. ( 29450710 )	Jabarin B....Gavriel H.	2018
4	Management of pediatric orbital cellulitis: A systematic review. ( 29859573 )	Wong S.J....Levi J.	2018
5	Cellulitis: what to measure, how to define? Systematic review of outcomes from cellulitis trials. ( 29785809 )	SunderkAPtter C.	2018
6	Tinea capitis mimicking dissecting cellulitis in three children. ( 29265536 )	Shastry J....DAVIS D.M.	2018
7	Clinical characteristics affecting length of stay in patients with cellulitis. ( 29415341 )	Grinlinton M....Wagener J.	2018
8	Orbital Cellulitis ( 29939678 )	Danishyar A....Sergent S.R.	2018
9	A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis. ( 29643005 )	Albert-Fort M....GonzA!lez-Candial M.	2018
10	Orbital cellulitis secondary to a fungal sinusitis caused by Scopulariopsis: The first case in Tunisia. ( 29709267 )	Kammoun S....Ayadi A.	2018
11	Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer. ( 29128228 )	Sagiv O....Esmaeli B.	2018
12	Non-tender recurrent scrotal cellulitis. ( 29440333 )	Abeykoon J.P....Enzler M.	2018
13	Orbital Cellulitis-When Computed Tomography Imaging Is Falsely Reassuring. ( 29768298 )	Basily A....Gutierrez P.	2018
14	Temporal Expression of Genes in Biofilm-Forming Ocular Candida albicans Isolated From Patients With Keratitis and Orbital Cellulitis. ( 29372251 )	Ranjith K....Shivaji S.	2018
15	Seasonality of cellulitis: evidence from Google Trends. ( 29765240 )	Zhang X....Wang W.	2018
16	Patient factors associated with nationwide emergency department utilization for cellulitis. ( 29958742 )	Li D.G....Mostaghimi A.	2018
17	Group B Streptococcal Cellulitis and Necrotizing Fasciitis in Infants: A Systematic Review. ( 29424798 )	Wojtera M....Strychowsky J.	2018
18	Recurrent Cellulitis in a Patient with Papillomatosis Cutis Lymphostatica. ( 29849304 )	Pak S....Valencia D.	2018
19	Langerhans cell histiocytosis in an 18-month-old child presenting as periorbital cellulitis. ( 29755272 )	Ali-Ridha A....Tang T.	2018
20	Cellulitis and Bacteremia due to <i>Neisseria weaveri</i> following a dog bite. ( 29942750 )	Shinha T.	2018
21	Estimating the health care costs associated with recurrent cellulitis managed in the outpatient setting. ( 29428738 )	St John J....Kroshinsky D.	2018
22	Wells syndrome (eosinophilic cellulitis) caused by adrenal insufficiency and relieved by cortisone supplementation. ( 29398098 )	Shen W.C....Chang C.H.	2018
23	Dissecting Cellulitis of the Scalp: A Rare Dermatological Manifestation of Crohn's Disease. ( 29430467 )	Syed T.A....Agudelo N.	2018
24	Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report. ( 29374464 )	Chakradeo K....De Silva J.	2018
25	The epidemiology and risk factors for recurrent severe lower limb cellulitis: a longitudinal cohort study. ( 29427799 )	Cannon J....Manning L.	2018
26	Incidence of Cellulitis among Children with Primary Lymphedema. ( 29791815 )	QuAcrAc I....Vikkula M.	2018
27	Anti-MDA5 Antibody-Positive Dermatomyositis Presenting with Cellulitis-Like Erythema on the Mandible as an Initial Symptom. ( 29867431 )	Hattori Y....Seishima M.	2018
28	Saksenaea vasiformis Orbital Cellulitis in an Immunocompetent Child Treated With Posaconazole. ( 29522137 )		2018
29	Cellulitis caused by the Burkholderia cepacia complex associated with contaminated chlorhexidine 2% scrub in five domestic cats. ( 29877147 )		2018
30	Nasal septal abscess as a sequela of orbital cellulitis: An uncommon presentation. ( 29899988 )		2018
31	Fifteen-minute consultation: Preseptal and orbital cellulitis. ( 29934359 )		2018
32	Treatment of a Klebsiella pneumoniae KPC cellulitis and gut decolonization with ceftazidime/avibactam in a migrant from Libya. ( 29336224 )		2018
33	Orbital Cellulitis from an Orbital Compressed Air and Diesel Explosion Injury. ( 29611376 )		2018
34	Eosinophilic infiltrate resembling eosinophilic cellulitis (Wells syndrome) in a patient with mycosis fungoides. ( 29469767 )		2018
35	Clostridium perfringens panophthalmitis and orbital cellulitis: a case report. ( 29631556 )		2018
36	Severe lower limb cellulitis: defining the epidemiology and risk factors for primary episodes in a population-based case-control study. ( 29427797 )		2018
37	Orbital apex syndrome from bacterial sinusitis without orbital cellulitis. ( 29468204 )		2018
38	<i>Shewanella</i> cellulitis and bacteremia following marine water exposure. ( 29942773 )		2018
39	Scleredema Diabeticorum with Superimposed Cellulitis and Abscess Formation. ( 29850291 )		2018
40	Ulcerative cellulitis of the arm: a case of primary cutaneous cryptococcosis. ( 29630156 )		2018
41	Eosinophilic cellulitis (Wells syndrome) successfully treated with mepolizumab. ( 29892672 )		2018
42	Trigeminal Trophic Syndrome Leading to Orbital Cellulitis. ( 29849238 )		2018
43	Erratum: Extranodal natural killer/T cell lymphoma, nasal type presenting as recurrent facial cellulitis. ( 29451197 )		2018
44	Hospital cost analysis of children with preseptal cellulitis. ( 29447901 )		2018
45	Variation in Care and Clinical Outcomes in Children Hospitalized With Orbital Cellulitis. ( 29208694 )		2018
46	Mass Compression from Recurrent Lymphoma Mimicking Lower Extremity Cellulitis. ( 29900086 )		2018
47	Cellulitis and Soft Tissue Infections. ( 29404597 )		2018
48	Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. ( 30118963 )	Alsalamah AK...Al-Faky YH	2018
49	Clinical and trichoscopic correlation of primary neutrophilic scarring alopecia: folliculitis decalvans and dissecting cellulitis. ( 30229638 )	Rossi A...Fortuna MC	2018
50	Two Cases of Micro-Arteriovenous Fistula in the Lower Extremity with Misdiagnosis of Refractory Cellulitis. ( 29682125 )	Tanaka M...Yokota K	2018

Sources

Genes for Cellulitis

Genes related to Cellulitis (0 elite genes):

(show all 19)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TNF	Tumor Necrosis Factor	Protein Coding	22.6	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	IL5	Interleukin 5	Protein Coding	22.13	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	RNASE3	Ribonuclease A Family Member 3	Protein Coding	21.28	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	COL17A1	Collagen Type XVII Alpha 1 Chain	Protein Coding	19.79	DISEASES inferred ¹⁵
5	DSG1	Desmoglein 1	Protein Coding	19.78	DISEASES inferred ¹⁵
6	DST	Dystonin	Protein Coding	19.24	DISEASES inferred ¹⁵
7	CYBB	Cytochrome B-245 Beta Chain	Protein Coding	18.18	DISEASES inferred ¹⁵
8	ATP2C1	ATPase Secretory Pathway Ca2+ Transporting 1	Protein Coding	18.17	DISEASES inferred ¹⁵
9	DSP	Desmoplakin	Protein Coding	17.5	DISEASES inferred ¹⁵
10	NCF2	Neutrophil Cytosolic Factor 2	Protein Coding	17.37	DISEASES inferred ¹⁵
11	NCF1	Neutrophil Cytosolic Factor 1	Protein Coding	17.35	DISEASES inferred ¹⁵
12	LAMA3	Laminin Subunit Alpha 3	Protein Coding	17.15	DISEASES inferred ¹⁵
13	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	17.01	GeneCards inferred via : Publications (show sections)
14	PPL	Periplakin	Protein Coding	16.96	DISEASES inferred ¹⁵
15	DSC3	Desmocollin 3	Protein Coding	16.9	DISEASES inferred ¹⁵
16	CYBA	Cytochrome B-245 Alpha Chain	Protein Coding	16.81	DISEASES inferred ¹⁵
17	ATP2A2	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2	Protein Coding	16.76	DISEASES inferred ¹⁵
18	DSG3	Desmoglein 3	Protein Coding	9.94	DISEASES inferred ¹⁵
19	CDH17	Cadherin 17	Protein Coding	7.02	DISEASES inferred ¹⁵

Sources

Variations for Cellulitis

Sources

Expression for Cellulitis

Search GEO for disease gene expression data for Cellulitis.

Sources

Pathways for Cellulitis

Pathways related to Cellulitis according to GeneCards Suite gene sharing:

(show all 24)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	13.88	CYBA CYBB DSG1 DSP IL1R1 IL5
2	Developmental Biology ⁶⁶ Show member pathways Axon guidance ⁶⁶	13.37	DSC3 DSG1 DSG3 DSP IL5 PPL
3	Antigen processing-Cross presentation ⁶⁶ Show member pathways Cross-presentation of particulate exogenous antigens (phagosomes) ⁶⁶ Endosomal/Vacuolar pathway ⁶⁶ ER-Phagosome pathway ⁶⁶ Immune response Antigen presentation by MHC class I ²²	12.32	CYBA CYBB NCF1 NCF2
4	Insulin receptor recycling ⁶⁶ Show member pathways Collecting duct acid secretion ³⁷ Epithelial cell signaling in Helicobacter pylori infection ³⁷ Iron uptake and transport ⁶⁶ ROS, RNS production in phagocytes ⁶⁶ Transferrin endocytosis and recycling ⁶⁶ Vibrio cholerae infection ³⁷	12.31	CYBA CYBB NCF1 NCF2
5	Keratinization ⁶⁶ Show member pathways Formation of the cornified envelope ⁶⁶	12.29	DSC3 DSG1 DSG3 DSP PPL
6	Immune response CCR3 signaling in eosinophils ²² Show member pathways Inhibitory action of Lipoxins on neutrophil migration ²²	12.18	CYBA CYBB NCF1 NCF2
7	G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins ²² Show member pathways G-protein signaling G-Protein alpha-12 signaling pathway ²²	12.02	COL17A1 CYBA CYBB IL1R1 LAMA3 NCF1
8	Phagosome ³⁷	11.99	CYBA CYBB NCF1 NCF2
9	Remodeling of Adherens Junctions ⁶⁴	11.87	CYBA CYBB NCF1 NCF2
10	Apoptotic cleavage of cellular proteins ⁶⁶ Show member pathways Apoptotic cleavage of cell adhesion proteins ⁶⁶ Apoptotic execution phase ⁶⁶ Caspase-mediated cleavage of cytoskeletal proteins ⁶⁶	11.85	DSG1 DSG3 DSP
11	Cytoskeleton remodeling Neurofilaments ²² Show member pathways Cytoskeleton remodeling Keratin filaments ²²	11.81	DSP DST PPL
12	Fluid shear stress and atherosclerosis ³⁷	11.8	CYBA IL1R1 NCF1 NCF2 TNF
13	Hematopoietic cell lineage ³⁷	11.75	IL1R1 IL5 TNF
14	Amoebiasis ³⁷	11.74	IL1R1 LAMA3 TNF
15	Toxoplasmosis ³⁷ Show member pathways Leishmaniasis ³⁷	11.7	CYBA CYBB LAMA3 NCF1 NCF2 TNF
16	Inhibitory action of Lipoxins on Superoxide production in neutrophils ²² Show member pathways Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions ²²	11.67	CYBA CYBB NCF1 NCF2
17	Osteoclast differentiation ³⁷	11.66	CYBA IL1R1 NCF1 NCF2 TNF
18	Innate Lymphoid Cell Differentiation Pathways ⁶⁵	11.64	IL1R1 IL5 TNF
19	Lung fibrosis ¹	11.5	DSP IL5 TNF
20	Detoxification of Reactive Oxygen Species ⁶⁶ Show member pathways Oxidative Stress Regulatory Pathway (Erythrocyte) ⁶¹ reactive oxygen species degradation ¹	11.36	CYBA CYBB NCF1 NCF2
21	G-protein signaling_Rac2 regulation pathway ²²	11.18	CYBA CYBB NCF1 NCF2
22	Overview of nanoparticle effects ¹	10.89	LAMA3 TNF
23	G-protein signaling_Rap2B regulation pathway ²²	10.84	CDH17 COL17A1 IL5 LAMA3 NCF2 TNF
24	RHO GTPases Activate NADPH Oxidases ⁶⁶	10.04	CYBA CYBB NCF1 NCF2

Sources

GO Terms for Cellulitis

Cellular components related to Cellulitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell junction	GO:0030054	9.86	CDH17 COL17A1 DSC3 DSG1 DSG3 DSP
2	cell-cell junction	GO:0005911	9.71	COL17A1 DSC3 DSG1 DSP
3	basement membrane	GO:0005604	9.65	COL17A1 DST LAMA3
4	cornified envelope	GO:0001533	9.55	DSC3 DSG1 DSG3 DSP PPL
5	hemidesmosome	GO:0030056	9.43	COL17A1 DST
6	phagolysosome	GO:0032010	9.32	NCF1 NCF2
7	NADPH oxidase complex	GO:0043020	9.26	CYBA CYBB NCF1 NCF2
8	desmosome	GO:0030057	9.02	DSC3 DSG1 DSG3 DSP PPL
9	membrane	GO:0016020	10.33	ATP2A2 ATP2C1 CDH17 COL17A1 CYBA CYBB
10	plasma membrane	GO:0005886	10.18	CDH17 COL17A1 CYBA CYBB DSC3 DSG1

Biological processes related to Cellulitis according to GeneCards Suite gene sharing:

(show all 22)

#	Name	GO ID	Score	Top Affiliating Genes
1	innate immune response	GO:0045087	9.98	CYBA CYBB NCF1 NCF2 RNASE3
2	cell adhesion	GO:0007155	9.98	ATP2A2 CDH17 DSC3 DSG1 DSG3 DST
3	neutrophil degranulation	GO:0043312	9.97	CYBA CYBB DSG1 DSP RNASE3
4	inflammatory response	GO:0006954	9.96	CYBA CYBB IL1R1 IL5 TNF
5	homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	9.85	CDH17 DSC3 DSG1 DSG3
6	keratinization	GO:0031424	9.85	DSC3 DSG1 DSG3 DSP PPL
7	wound healing	GO:0042060	9.78	DSP DST PPL
8	electron transport chain	GO:0022900	9.78	CYBA CYBB NCF1 NCF2
9	cellular response to oxidative stress	GO:0034599	9.77	ATP2A2 CYBA CYBB
10	cornification	GO:0070268	9.72	DSC3 DSG1 DSG3 DSP PPL
11	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO:0016339	9.71	ATP2C1 CDH17 DSG1
12	vascular endothelial growth factor receptor signaling pathway	GO:0048010	9.71	CYBA CYBB NCF1 NCF2
13	intermediate filament cytoskeleton organization	GO:0045104	9.67	DSP DST PPL
14	epidermis development	GO:0008544	9.65	ATP2A2 ATP2C1 COL17A1 DSP LAMA3
15	positive regulation of podosome assembly	GO:0071803	9.59	IL5 TNF
16	hydrogen peroxide biosynthetic process	GO:0050665	9.57	CYBA CYBB
17	hemidesmosome assembly	GO:0031581	9.54	COL17A1 DST LAMA3
18	cellular response to L-glutamine	GO:1904845	9.52	CYBA CYBB
19	response to aldosterone	GO:1904044	9.51	CYBA CYBB
20	superoxide metabolic process	GO:0006801	9.46	CYBA CYBB NCF1 NCF2
21	respiratory burst	GO:0045730	9.26	CYBA CYBB NCF1 NCF2
22	superoxide anion generation	GO:0042554	8.92	CYBA CYBB NCF1 NCF2

Molecular functions related to Cellulitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	calcium ion binding	GO:0005509	9.63	ATP2A2 CDH17 DSC3 DSG1 DSG3 DST
2	structural molecule activity	GO:0005198	9.56	DSP DST LAMA3 PPL
3	proton-exporting ATPase activity, phosphorylative mechanism	GO:0008553	9.4	ATP2A2 ATP2C1
4	calcium-transporting ATPase activity	GO:0005388	9.37	ATP2A2 ATP2C1
5	superoxide-generating NADPH oxidase activator activity	GO:0016176	9.32	NCF1 NCF2
6	electron transfer activity	GO:0009055	9.26	CYBA CYBB NCF1 NCF2
7	superoxide-generating NADPH oxidase activity	GO:0016175	8.92	CYBA CYBB NCF1 NCF2

Sources

Sources for Cellulitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia