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MCID: CLL003
MIFTS: 61

Cellulitis

Categories: Immune diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Cellulitis

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MalaCards integrated aliases for Cellulitis:

Name: Cellulitis 12 30 56 44 45 15 17 74

Classifications:

MalaCards categories:
Anatomical: Skin diseases Immune diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:3488
MeSH 45 D002481
SNOMED-CT 69 62837005 74276003
ICD10 34 L03 L03.9 L03.90
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Summaries for Cellulitis

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MedlinePlus : 44 Cellulitis is an infection of the skin and deep underlying tissues. Group A strep (streptococcal) bacteria are the most common cause. The bacteria enter your body when you get an injury such as a bruise, burn, surgical cut, or wound. Symptoms include Fever and chills Swollen glands or lymph nodes A rash with painful, red, tender skin. The skin may blister and scab over. Your health care provider may take a sample or culture from your skin or do a blood test to identify the bacteria causing infection. Treatment is with antibiotics. They may be oral in mild cases, or intravenous (by IV) for more severe cases. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Cellulitis is related to wells syndrome and scleritis, and has symptoms including fever, pruritus and exanthema. An important gene associated with Cellulitis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and Developmental Biology. The drugs Clindamycin and Lincomycin have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and testes, and related phenotypes are cellular and growth/size/body region

Disease Ontology : 12 A skin disease where there is a diffuse infection of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin. Cellulitis can be caused by normal skin flora or by exogenous bacteria, and often occurs where the skin has previously been broken

Wikipedia : 77 Cellulitis is a bacterial infection involving the inner layers of the skin. It specifically affects the... more...

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Related Diseases for Cellulitis

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Diseases related to Cellulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 430)
# Related Disease Score Top Affiliating Genes
1 wells syndrome 33.3 IL1R1 IL5 RNASE3
2 scleritis 30.3 IL5 TNF
3 pyoderma 29.9 DSG1 IL1R1 TNF
4 churg-strauss syndrome 29.9 IL5 RNASE3 TNF
5 keratoconjunctivitis 29.8 IL5 RNASE3 TNF
6 bronchiolitis 29.8 IL5 RNASE3 TNF
7 chronic granulomatous disease 29.2 CYBA CYBB NCF1 NCF2
8 pemphigus foliaceus 29.2 DSG1 DSG3 DST PPL
9 pemphigus vulgaris 28.6 DSC3 DSG1 DSG3 DSP DST PPL
10 pemphigus 27.7 ATP2C1 COL17A1 DSC1 DSC3 DSG1 DSG3
11 bullous pemphigoid 27.6 COL17A1 DSG1 DSG3 DSP DST IL5
12 skin disease 26.5 ATP2C1 COL17A1 DSC1 DSC3 DSG1 DSG3
13 orbital cellulitis 12.6
14 perifolliculitis capitis abscedens et suffodiens, familial 12.1
15 tinea unguium 11.9
16 ludwig's angina 11.8
17 parametritis 11.4
18 erysipelas 11.4
19 lacrimal duct defect 11.3
20 erysipeloid 11.3
21 nocardiosis 11.3
22 lymphatic malformation 1 11.0
23 whim syndrome 11.0
24 fusariosis 11.0
25 hereditary lymphedema ii 11.0
26 clear cell acanthoma 11.0
27 elizabethkingia anophelis infection 11.0
28 angioimmunoblastic lymphadenopathy with dysproteinemia 10.4 IL5 TNF
29 loeffler endocarditis 10.4 IL5 RNASE3
30 lichen planus pemphigoides 10.4 COL17A1 DST
31 vulvar vestibulitis syndrome 10.4 IL1R1 TNF
32 sinusitis 10.4
33 cow milk allergy 10.4 IL5 RNASE3 TNF
34 haemophilus influenzae 10.3
35 conjunctival disease 10.3 IL5 RNASE3 TNF
36 paragonimiasis 10.3 IL5 RNASE3
37 erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige 10.3 DSG1 DSP
38 linear iga disease 10.3 COL17A1 DST
39 neurotic excoriation 10.3 COL17A1 DST
40 common cold 10.3 IL1R1 IL5 RNASE3
41 cough variant asthma 10.3 IL5 RNASE3
42 nose disease 10.3 IL5 RNASE3 TNF
43 thrombosis 10.3
44 pemphigoid gestationis 10.3 COL17A1 DST IL5
45 parasitic helminthiasis infectious disease 10.3 IL5 RNASE3 TNF
46 upper respiratory tract disease 10.3 IL5 RNASE3 TNF
47 gastroenteritis 10.3 IL5 RNASE3 TNF
48 cold urticaria 10.3 IL1R1 RNASE3
49 bronchial disease 10.3 IL5 RNASE3 TNF
50 schistosomiasis 10.3 IL5 RNASE3 TNF

Graphical network of the top 20 diseases related to Cellulitis:



Diseases related to Cellulitis
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Symptoms & Phenotypes for Cellulitis

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UMLS symptoms related to Cellulitis:


fever, pruritus, exanthema

MGI Mouse Phenotypes related to Cellulitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.18 ATP2C1 CYBA CYBB DSC1 DSC3 DSG3
2 growth/size/body region MP:0005378 10.1 ATP2C1 CYBB DSC1 DSG1 DSG3 DSP
3 hematopoietic system MP:0005397 10 CDH17 CYBA CYBB DSG3 IL1R1 IL5
4 digestive/alimentary MP:0005381 9.97 CYBA CYBB DSG3 DSP IL5 LAMA3
5 immune system MP:0005387 9.93 CDH17 CYBA CYBB DSC1 DSG3 IL1R1
6 adipose tissue MP:0005375 9.91 CYBA CYBB DSG1 DSG3 IL1R1 TNF
7 integument MP:0010771 9.7 ATP2C1 DSC1 DSC3 DSG1 DSG3 DSP
8 respiratory system MP:0005388 9.23 CYBA DSG3 IL1R1 IL5 LAMA3 NCF1
Sources

Drugs & Therapeutics for Cellulitis

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Drugs for Cellulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 416)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 18323-44-9 29029
2
Lincomycin Approved, Vet_approved Phase 4 154-21-2 656509
3
Permethrin Approved, Investigational Phase 4,Not Applicable 52645-53-1 40326
4
Mupirocin Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 12650-69-0 446596
5
Cefazolin Approved Phase 4,Phase 3,Phase 2,Not Applicable 25953-19-9 656510 33255
6
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
7
Vancomycin Approved Phase 4,Phase 2,Phase 3 1404-90-6 441141 14969
8
Daptomycin Approved, Investigational Phase 4,Phase 3,Phase 2 103060-53-3 16129629
9
Oxacillin Approved, Investigational Phase 4,Phase 3,Phase 2 66-79-5 6196
10
Retapamulin Approved Phase 4,Phase 3,Phase 1 224452-66-8 6918462
11
Cephalexin Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 15686-71-2 27447
12
Sulbactam Approved Phase 4 68373-14-8
13
Clavulanate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 58001-44-8 5280980
14
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 26787-78-0 33613
15
Tigecycline Approved Phase 4,Phase 3,Phase 2 220620-09-7 5282044
16
Teicoplanin Approved, Investigational Phase 4,Phase 3 61036-62-2
17
Sultamicillin Approved, Investigational Phase 4 76497-13-7
18
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
19
Cefdinir Approved Phase 4 91832-40-5 6915944
20
Ceftaroline fosamil Approved, Investigational Phase 4,Phase 2,Phase 3 229016-73-3
21
Oritavancin Approved, Investigational Phase 4,Phase 3,Phase 2 171099-57-3 16129632
22
Warfarin Approved Phase 4 81-81-2 6691 54678486
23
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492 6473866
24
Pimecrolimus Approved, Investigational Phase 4 137071-32-0 17753757 6447131
25
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 55-56-1 2713 9552079
26
Ivermectin Approved, Investigational, Vet_approved Phase 4,Not Applicable 70288-86-7 6474909
27
Azithromycin Approved Phase 4,Phase 3,Not Applicable 83905-01-5 55185 447043
28
Conivaptan Approved, Investigational Phase 4 210101-16-9 151171
29
Fondaparinux Approved, Investigational Phase 4 104993-28-4
30
Nafcillin Approved, Investigational Phase 4,Phase 2 985-16-0, 147-52-4 8982
31
Cloxacillin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 61-72-3 6098
32
Thrombin Approved, Investigational Phase 4
33
Petrolatum Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 8009-03-8
34
Dalbavancin Approved, Investigational Phase 4,Phase 3 171500-79-1, 91097-81-3 122186
35
Fusidic Acid Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 6990-06-3 3000226
36
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
37
Sargramostim Approved, Investigational Phase 4 123774-72-1, 83869-56-1
38
Lenograstim Approved, Investigational Phase 4 135968-09-1
39
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
40
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
41
Serine Approved, Nutraceutical Phase 4 56-45-1 5951
42 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
43 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Floxacillin Phase 4,Phase 3,Not Applicable
45 Clindamycin palmitate Phase 4,Phase 2,Phase 3,Not Applicable
46 Clindamycin phosphate Phase 4,Phase 2,Phase 3,Not Applicable
47 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 methicillin Phase 4,Phase 3,Phase 2,Not Applicable
49 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
50 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 409)
# Name Status NCT ID Phase Drugs
1 Adjunctive Clindamycin for Cellulitis: C4C Trial. Unknown status NCT01876628 Phase 4 Flucloxacillin and Clindamycin;Flucloxacillin and placebo
2 RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg Completed NCT00552799 Phase 4 Penicillin VK
3 Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas Completed NCT00295178 Phase 4 Daptomycin;Vancomycin
4 The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin Completed NCT01626560 Phase 4 Daptomycin;Vancomycin
5 Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections Completed NCT01549613 Phase 4 Daptomycin;Vancomycin
6 Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections. Completed NCT00555061 Phase 4 Retapamulin Ointment, 1%
7 Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA Completed NCT01419184 Phase 4 Daptomycin;Vancomycin
8 Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections Completed NCT00352612 Phase 4 clindamycin;cephalexin
9 Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections Completed NCT00368537 Phase 4 Tigecycline;ampicillin-sulbactam
10 A Study to Compare Cefdinir and Cephalexin for the Treatment of Mild to Moderate Uncomplicated Skin Infections Completed NCT00234949 Phase 4 cefdinir;cephalexin
11 Safety and Efficacy Study of Altabax Ointment in the Treatment of Secondarily Infected Atopic Dermatitis Completed NCT01064947 Phase 4 Retapamulin 1%
12 Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA Completed NCT02582203 Phase 4 Ceftaroline;Vancomycin
13 Study of Wound Packing After Superficial Skin Abscess Drainage Completed NCT00746109 Phase 4
14 A Study to Evaluate the Safety of a Single IV Dose of Orbactiv (Oritavancin) in Subjects on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI) Completed NCT02452918 Phase 4 Oritavancin
15 Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial Completed NCT00799292 Phase 4 Vasopressin
16 Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis Completed NCT00121381 Phase 4 Pimecrolimus plus topical corticosteroid (TCS);Pimecrolimus vehicle (Placebo) plus topical corticosteroid (TCS)
17 Effect of Chlorhexidine Skin Cleansing on Skin Flora Completed NCT00198679 Phase 4 Chlorhexidine
18 Azithromycin - Ivermectin Mass Drug Administration for Skin Disease Completed NCT02775617 Phase 4 Ivermectin;Azithromycin;Permethrin
19 Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions Completed NCT02137447 Phase 4
20 Appendicectomy Skin Closure Technique: Changing Paradigms (ASC) Completed NCT02625987 Phase 4
21 A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia Completed NCT00435591 Phase 4 Conivaptan;placebo
22 World-wide Randomized Antibiotic Envelope Infection Prevention Trial Completed NCT02277990 Phase 4
23 The Effects of Arixtra on Wound Drainage Following Total Joint Arthroplasty Completed NCT00909064 Phase 4 Fondaparinux Sodium (Arixtra)
24 Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure Infections Completed NCT00711802 Phase 4 Daptomycin;Standard of Care (SOC)
25 Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty Completed NCT01410240 Phase 4 FLOSEAL Hemostatic Matrix + Standard of care
26 Topical Therapy for Prevention of Infections in Preterm Infants Completed NCT00162747 Phase 4 Aquaphor;Sunflower Seed Oil
27 Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection Completed NCT01126268 Phase 4 Retapamulin (Altabax)
28 Hospital Avoidance Strategies for ABSSSI Recruiting NCT03372941 Phase 4 Dalbavancin
29 Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence Recruiting NCT02566928 Phase 4 2% mupirocin ointment
30 GCSF in Alcoholic Hepatitis Recruiting NCT03703674 Phase 4 GCSF
31 G-CSF Plus NAC In Severe Alcoholic Hepatitis Recruiting NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
32 Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections Recruiting NCT03426761 Phase 4 Dalbavancin;Vancomycin
33 Group A Pharyngitis in Children: The GASPARD Study Recruiting NCT03264911 Phase 4 Amoxicillin or Placebo
34 Penicillin for the Emergency Department Outpatient Treatment of CELLulitis Not yet recruiting NCT02922686 Phase 4 Flucloxacillin;Phenoxymethylpenicillin;Placebo (for phenoxymethylpenicillin)
35 Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery Not yet recruiting NCT03887299 Phase 4
36 Duration of ANtibiotic Therapy for CEllulitis Terminated NCT02032654 Phase 4 Flucloxacillin;Placebo (for flucloxacillin)
37 Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure Infections Terminated NCT00463801 Phase 4 Daptomycin
38 Silver Impregnated Dressings to Reduce Wound Complications in Obese Patients at Cesarean Section Terminated NCT01528696 Phase 4
39 Local Application of Vancomycin Powder in Grade I-IIIA Open Fractures Terminated NCT02400112 Phase 4 Vancomycin
40 Fucidin® Cream in the Treatment of Impetigo Terminated NCT00986856 Phase 4 Fucidin® cream
41 Use of Santyl Within an Accountable Care Organization Withdrawn NCT02716519 Phase 4
42 Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department Unknown status NCT00323219 Phase 3 Cefazolin and Moxifloxacin
43 Citriodiol® and Impetigo Unknown status NCT01611909 Phase 2, Phase 3 p-menthane-3,8-diol oil
44 A Randomized Clinical Trial to Prevent Recurrent CA-MRSA Infection Completed NCT00560599 Phase 3 mupirocin and chlorhexidine;mupirocin, chlorhexidine, & household cleaning/disinfection
45 Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Skin Infections Completed NCT01400867 Phase 2, Phase 3 Ceftaroline fosamil;Vancomycin +/- Aztreonam or Cefazolin +/- Aztreonam;Cephalexin or Clindamycin or Linezolid
46 Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections Completed NCT00424190 Phase 3 IV Vancomycin plus IV Aztreonam;Ceftaroline
47 Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections Completed NCT00423657 Phase 3 ceftaroline;vancomycin plus aztreonam;Placebo
48 Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA Completed NCT00852540 Phase 3 Retpamulin Ointment, 1%;Linezolid
49 Retapamulin Versus Placebo in Secondarily-Infected Traumatic Lesions (SITL) Completed NCT00684177 Phase 3 Retapamulin Ointment, 1%;Placebo ointment
50 A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections Completed NCT00249197 Phase 3 levofloxacin

Search NIH Clinical Center for Cellulitis

Cochrane evidence based reviews: cellulitis

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Genetic Tests for Cellulitis

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Genetic tests related to Cellulitis:

# Genetic test Affiliating Genes
1 Cellulitis 30
Sources

Anatomical Context for Cellulitis

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MalaCards organs/tissues related to Cellulitis:

42
Skin, Breast, Testes, Colon, Lymph Node, Kidney, Liver
Sources

Publications for Cellulitis

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Articles related to Cellulitis:

(show top 50) (show all 2578)
# Title Authors Year
1
Impact of health care-associated community-onset cellulitis in Korea: a multicenter study. ( 30680560 )
2019
2
Adherence to antibiotic guidelines for erysipelas or cellulitis is associated with a favorable outcome. ( 30685804 )
2019
3
Rhino-orbital Mucormycosis presenting as facial cellulitis in a patient with high-risk acute myeloid leukemia in relapse. ( 30686650 )
2019
4
Lower limb cellulitis: low diagnostic accuracy and underdiagnosis of risk factors. ( 30687958 )
2019
5
CELLULITIS: A mnemonic to increase accuracy of cellulitis diagnosis. ( 30710907 )
2019
6
Predisposing factors of necrotizing fasciitis with comparison to cellulitis in Taiwan: A nationwide population-based case-control study. ( 30738634 )
2019
7
Increased antistreptolysin O serum levels in cellulitis recurrences and head and neck disease localization. ( 30746690 )
2019
8
Pediatric preseptal and orbital cellulitis: A 10-year experience. ( 30772617 )
2019
9
Common Community-acquired Bacterial Skin and Soft-tissue Infections in Children: an Intersociety Consensus on Impetigo, Abscess, and Cellulitis Treatment. ( 30777258 )
2019
10
Clostridioides difficile-related toxic megacolon after Cryptococcus neoformans cellulitis: A complex of two rare infections in an immunocompromised host. ( 30797689 )
2019
11
Analysis of Readmissions Following Hospitalization for Cellulitis in the United States. ( 30810708 )
2019
12
Evaluation of an emergency department to outpatient parenteral antibiotic therapy program for cellulitis. ( 30824277 )
2019
13
A 60-year-old woman with recurrent cellulitis. ( 30833492 )
2019
14
Lipodermatosclerosis: the common skin condition often treated as cellulitis. ( 30838992 )
2019
15
A systematic review showing the lack of diagnostic criteria and tools developed for lower limb cellulitis. ( 30844076 )
2019
16
Efficacy and safety of intravenous ceftriaxone at home versus intravenous flucloxacillin in hospital for children with cellulitis (CHOICE): a single-centre, open-label, randomised, controlled, non-inferiority trial. ( 30853250 )
2019
17
Recurrent periorbital cellulitis associated with rhinosinusitis in children: Characteristics, course of disease, and management paradigm. ( 30856372 )
2019
18
Patients' understanding of cellulitis and their information needs: a mixed-methods study in primary and secondary care. ( 30858335 )
2019
19
Herpetic whitlow of the toe presenting with severe viral cellulitis. ( 30859616 )
2019
20
The association of cellulitis incidence and meteorological factors in Taiwan. ( 30869041 )
2019
21
Diagnosis and Management of Non-Purulent Cellulitis in the Emergency Department. ( 30892175 )
2019
22
Development and Validation of a Cellulitis Risk Score: The Melbourne ASSET Score. ( 30606746 )
2019
23
Daily outpatient intravenous antibiotic therapy for the management of paediatric periorbital cellulitis, a retrospective case series. ( 30638306 )
2019
24
Giant cellulitis-like Sweet syndrome as an initial clinical presentation of acute myeloblastic leukemia with t(6;9)(p23;q34): DEK-CAN and internal duplications of FMS-like tyrosine kinase 3. ( 30659317 )
2019
25
Antibiotic stewardship: The treatment of uncomplicated lower limb cellulitis. ( 30674428 )
2019
26
Systemic corticosteroids may be beneficial for managing severe or refractory orbital cellulitis in children. ( 29920768 )
2018
27
Non-invasive assessment of cellulitis from snapshot hyperspectral imaging - A primary study. ( 29368433 )
2018
28
Indicators for imaging in periorbital cellulitis secondary to rhinosinusitis. ( 29450710 )
2018
29
Management of pediatric orbital cellulitis: A systematic review. ( 29859573 )
2018
30
Cellulitis: what to measure, how to define? Systematic review of outcomes from cellulitis trials. ( 29785809 )
2018
31
Tinea capitis mimicking dissecting cellulitis in three children. ( 29265536 )
2018
32
Clinical characteristics affecting length of stay in patients with cellulitis. ( 29415341 )
2018
33
Orbital Cellulitis ( 29939678 )
2018
34
A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis. ( 29643005 )
2018
35
Orbital cellulitis secondary to a fungal sinusitis caused by Scopulariopsis: The first case in Tunisia. ( 29709267 )
2018
36
Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer. ( 29128228 )
2018
37
Non-tender recurrent scrotal cellulitis. ( 29440333 )
2018
38
Orbital Cellulitis-When Computed Tomography Imaging Is Falsely Reassuring. ( 29768298 )
2018
39
Temporal Expression of Genes in Biofilm-Forming Ocular Candida albicans Isolated From Patients With Keratitis and Orbital Cellulitis. ( 29372251 )
2018
40
Seasonality of cellulitis: evidence from Google Trends. ( 29765240 )
2018
41
Patient factors associated with nationwide emergency department utilization for cellulitis. ( 29958742 )
2018
42
Group B Streptococcal Cellulitis and Necrotizing Fasciitis in Infants: A Systematic Review. ( 29424798 )
2018
43
Recurrent Cellulitis in a Patient with Papillomatosis Cutis Lymphostatica. ( 29849304 )
2018
44
Langerhans cell histiocytosis in an 18-month-old child presenting as periorbital cellulitis. ( 29755272 )
2018
45
Cellulitis and Bacteremia due to <i>Neisseria weaveri</i> following a dog bite. ( 29942750 )
2018
46
Estimating the health care costs associated with recurrent cellulitis managed in the outpatient setting. ( 29428738 )
2018
47
Wells syndrome (eosinophilic cellulitis) caused by adrenal insufficiency and relieved by cortisone supplementation. ( 29398098 )
2018
48
Dissecting Cellulitis of the Scalp: A Rare Dermatological Manifestation of Crohn's Disease. ( 29430467 )
2018
49
Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report. ( 29374464 )
2018
50
The epidemiology and risk factors for recurrent severe lower limb cellulitis: a longitudinal cohort study. ( 29427799 )
2018
Sources

Variations for Cellulitis

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Expression for Cellulitis

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Search GEO for disease gene expression data for Cellulitis.
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Pathways for Cellulitis

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Pathways related to Cellulitis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 67
Show member pathways
 13.91 CYBA CYBB DSC1 DSG1 DSP IL1R1
2
Developmental Biology 67
Show member pathways
 13.37 DSC1 DSC3 DSG1 DSG3 DSP IL5
3
Cell junction organization 67
Show member pathways
 12.57 CDH17 COL17A1 DST LAMA3 PLEC
4
Antigen processing-Cross presentation 67
Show member pathways
 12.36 CYBA CYBB NCF1 NCF2
5
Insulin receptor recycling 67
Show member pathways
 12.35 CYBA CYBB NCF1 NCF2
6
Immune response CCR3 signaling in eosinophils 23
Show member pathways
 12.22 CYBA CYBB NCF1 NCF2
7
Keratinization 67
Show member pathways
 12.19 DSC1 DSC3 DSG1 DSG3 DSP PPL
8
G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins 23
Show member pathways
 12.05 COL17A1 CYBA CYBB IL1R1 LAMA3 NCF1
9
Phagosome 38
12.01 CYBA CYBB NCF1 NCF2
10
Adhesion 4
11.89 CDH17 DSP PLEC
11
Remodeling of Adherens Junctions 65
11.89 CYBA CYBB NCF1 NCF2
12
Fluid shear stress and atherosclerosis 38
11.86 CYBA IL1R1 NCF1 NCF2 TNF
13
Apoptotic cleavage of cellular proteins 67
Show member pathways
 11.82 DSG1 DSG3 DSP PLEC
14
Hematopoietic cell lineage 38
11.77 IL1R1 IL5 TNF
15
Cytoskeleton remodeling Neurofilaments 23
Show member pathways
 11.77 DSP DST PLEC PPL
16
Amoebiasis 38
11.75 IL1R1 LAMA3 TNF
17
Toxoplasmosis 38
Show member pathways
 11.7 CYBA CYBB LAMA3 NCF1 NCF2 TNF
18
Innate Lymphoid Cell Differentiation Pathways 66
11.66 IL1R1 IL5 TNF
19
Osteoclast differentiation 38
11.66 CYBA IL1R1 NCF1 NCF2 TNF
20
Lung fibrosis 1
11.54 DSP IL5 TNF
21
Detoxification of Reactive Oxygen Species 67
Show member pathways
 11.41 CYBA CYBB NCF1 NCF2
22
G-protein signaling_Rac2 regulation pathway 23
11.19 CYBA CYBB NCF1 NCF2
23
Overview of nanoparticle effects 1
10.9 LAMA3 TNF
24
G-protein signaling_Rap2B regulation pathway 23
10.86 CDH17 COL17A1 IL5 LAMA3 NCF2 TNF
25
RHO GTPases Activate NADPH Oxidases 67
10.04 CYBA CYBB NCF1 NCF2
Sources

GO Terms for Cellulitis

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Cellular components related to Cellulitis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.85 CDH17 COL17A1 DSC1 DSC3 DSG1 DSG3
2 intermediate filament GO:0005882 9.78 DSP DST PLEC PPL
3 cell-cell junction GO:0005911 9.76 COL17A1 DSC3 DSG1 DSP
4 basement membrane GO:0005604 9.69 COL17A1 DST LAMA3
5 ficolin-1-rich granule membrane GO:0101003 9.67 DSC1 DSG1 DSP
6 NADPH oxidase complex GO:0043020 9.56 CYBA CYBB NCF1 NCF2
7 hemidesmosome GO:0030056 9.5 COL17A1 DST PLEC
8 cornified envelope GO:0001533 9.43 DSC1 DSC3 DSG1 DSG3 DSP PPL
9 phagolysosome GO:0032010 9.4 NCF1 NCF2
10 desmosome GO:0030057 9.1 DSC1 DSC3 DSG1 DSG3 DSP PPL
11 membrane GO:0016020 10.34 ATP2C1 CDH17 COL17A1 CYBA CYBB DSC1
12 plasma membrane GO:0005886 10.24 CDH17 COL17A1 CYBA CYBB DSC1 DSC3

Biological processes related to Cellulitis according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.97 CYBA CYBB IL1R1 IL5 TNF
2 keratinization GO:0031424 9.88 DSC1 DSC3 DSG1 DSG3 DSP PPL
3 epidermis development GO:0008544 9.84 ATP2C1 COL17A1 DSP LAMA3
4 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.83 CDH17 DSC1 DSC3 DSG1 DSG3
5 electron transport chain GO:0022900 9.81 CYBA CYBB NCF1 NCF2
6 wound healing GO:0042060 9.8 DSP DST PLEC PPL
7 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.76 CYBA CYBB NCF1 NCF2
8 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9.74 ATP2C1 CDH17 DSG1
9 intermediate filament cytoskeleton organization GO:0045104 9.67 DSP DST PLEC PPL
10 superoxide metabolic process GO:0006801 9.62 CYBA CYBB NCF1 NCF2
11 positive regulation of podosome assembly GO:0071803 9.59 IL5 TNF
12 hydrogen peroxide biosynthetic process GO:0050665 9.58 CYBA CYBB
13 cellular response to L-glutamine GO:1904845 9.56 CYBA CYBB
14 respiratory burst GO:0045730 9.56 CYBA CYBB NCF1 NCF2
15 response to aldosterone GO:1904044 9.55 CYBA CYBB
16 superoxide anion generation GO:0042554 9.46 CYBA CYBB NCF1 NCF2
17 cornification GO:0070268 9.43 DSC1 DSC3 DSG1 DSG3 DSP PPL
18 hemidesmosome assembly GO:0031581 8.92 COL17A1 DST LAMA3 PLEC
19 cell adhesion GO:0007155 10.02 CDH17 DSC1 DSC3 DSG1 DSG3 DST
20 innate immune response GO:0045087 10 CYBA CYBB NCF1 NCF2 RNASE3
21 neutrophil degranulation GO:0043312 10 CYBA CYBB DSC1 DSG1 DSP RNASE3

Molecular functions related to Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.73 CDH17 DSC1 DSC3 DSG1 DSG3 DST
2 structural constituent of cytoskeleton GO:0005200 9.58 DSP PLEC PPL
3 structural molecule activity GO:0005198 9.55 DSP DST LAMA3 PLEC PPL
4 cytoskeletal protein binding GO:0008092 9.54 CDH17 DST PLEC
5 superoxide-generating NADPH oxidase activator activity GO:0016176 9.32 NCF1 NCF2
6 electron transfer activity GO:0009055 9.26 CYBA CYBB NCF1 NCF2
7 superoxide-generating NADPH oxidase activity GO:0016175 8.92 CYBA CYBB NCF1 NCF2
Sources

Sources for Cellulitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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