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MCID: CLL003
MIFTS: 54

Cellulitis

Categories: Immune diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Cellulitis

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MalaCards integrated aliases for Cellulitis:

Name: Cellulitis 12 54 42 43 15 17 71 32

Classifications:

MalaCards categories:
Anatomical: Skin diseases Immune diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:3488
MeSH 43 D002481
ICD10 32 L03 L03.9 L03.90
UMLS 71 C0007642 C0007646
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Summaries for Cellulitis

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MedlinePlus : 42 Cellulitis is an infection of the skin and deep underlying tissues. Group A strep (streptococcal) bacteria are the most common cause. The bacteria enter your body when you get an injury such as a bruise, burn, surgical cut, or wound. Symptoms include Fever and chills Swollen glands or lymph nodes A rash with painful, red, tender skin. The skin may blister and scab over. Your health care provider may take a sample or culture from your skin or do a blood test to identify the bacteria causing infection. Treatment is with antibiotics. They may be oral in mild cases, or intravenous (by IV) for more severe cases.

MalaCards based summary : Cellulitis is related to wells syndrome and dermatophytosis, and has symptoms including fever, pruritus and exanthema. An important gene associated with Cellulitis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and PAK Pathway. The drugs Cefazolin and Lincomycin have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and bone, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A skin disease where there is a diffuse infection of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin. Cellulitis can be caused by normal skin flora or by exogenous bacteria, and often occurs where the skin has previously been broken: cracks in the skin, cuts, blisters, burns, insect bites, surgical wounds, or sites of intravenous catheter insertion.

Wikipedia : 74 Cellulitis is a bacterial infection involving the inner layers of the skin. It specifically affects the... more...

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Related Diseases for Cellulitis

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Diseases related to Cellulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1019)
# Related Disease Score Top Affiliating Genes
1 wells syndrome 34.1 RNASE3 IL5 IL1R1
2 dermatophytosis 31.5 DEFB4A CD4 CCR6
3 conjunctivitis 31.5 TNF RNASE3 IL5
4 cryptococcosis 31.4 TNF CD8A CD4 CCR6
5 dermatitis 31.4 TNF IL5 DSG1 CHI3L1 CCR6
6 exanthem 31.3 TNF ICOSLG CD8A CD4 CCR6
7 dacryoadenitis 31.3 ICOSLG CD8A CD4 CCR6
8 contact dermatitis 31.3 TNF IL5 CD4
9 chickenpox 31.2 TNF CD8A CD4 CCR6
10 hidradenitis 31.2 TNF DSG3 DSG1 CAMP
11 hidradenitis suppurativa 31.2 TNF DSG3 DSG1 CAMP
12 pharyngitis 31.1 TNF CD8A CD4
13 lymphadenitis 31.1 TNF SERPINA3 ICOSLG CD4 CCR6
14 scleritis 31.1 TNF IL5 CCR6
15 histiocytosis 31.0 TNF SERPINA3 CCR6
16 keratitis, hereditary 31.0 TNF CD4 CCR6
17 pyoderma gangrenosum 31.0 TNF IL1R1 CCR6
18 folliculitis 30.9 TNF IL5 DEFB4A CD4 CCR6
19 pyoderma 30.9 TNF IL1R1 DSG3 DSG1 CCR6
20 pneumonia 30.9 TNF IL5 DEFB4A CD8A
21 impetigo 30.9 DSG3 DSG1 CCR6 CAMP
22 allergic hypersensitivity disease 30.9 TNF RNASE3 IL5 ICOSLG CD4 CCR6
23 bacterial infectious disease 30.9 TNF SERPINA3 IL1R1 ICOSLG DEFB4A CD8A
24 crohn's disease 30.9 TNF ICOSLG CD4 CCR6
25 miliary tuberculosis 30.8 TNF CD8A CD4
26 urticaria 30.8 TNF RNASE3 IL5
27 temporal arteritis 30.8 TNF SERPINA3 CD8A CD4 CCR6
28 acute cystitis 30.8 TNF SERPINA3 CD4 CCR6 CAMP
29 keratoconjunctivitis 30.8 TNF RNASE3 IL5
30 crohn's colitis 30.8 TNF DEFB4A CCR6
31 lung disease 30.8 TNF SERPINA3 RNASE3 IL5 CD8A CAMP
32 paranasal sinus disease 30.8 TNF RNASE3 IL5 ICOSLG CD8A CD4
33 sarcoidosis 1 30.8 TNF SERPINA3 ICOSLG CHI3L1 CD8A CD4
34 urethritis 30.7 TNF DEFB4A CD4 CAMP
35 optic nerve disease 30.7 TNF SERPINA3 ICOSLG CD8A CD4 CCR6
36 histoplasmosis 30.7 TNF CD8A CD4 CCR6
37 leukemia, chronic lymphocytic 30.7 TNF ICOSLG FLT3 CD8A CD4 CCR6
38 psoriasis 30.7 TNF IL5 IL1R1 DEFB4A CD4 CCR6
39 toxic shock syndrome 30.7 TNF IL1R1 CAMP
40 herpes zoster 30.7 TNF ICOSLG COL17A1 CD8A CD4 CCR6
41 cerebritis 30.6 TNF CD8A CD4
42 immune deficiency disease 30.6 TNF SERPINA3 ICOSLG CYBB CD4 CCR6
43 chorioretinitis 30.6 TNF CD8A CD4
44 leprosy 3 30.6 TNF IL5 CD8A CD4 CCR6
45 onchocerciasis 30.6 SERPINA3 RNASE3 IL5 DSG1
46 lymphangioma 30.6 SERPINA3 FLT4 CCR6
47 allergic contact dermatitis 30.6 TNF IL5 DEFB4A CD4
48 systemic lupus erythematosus 30.6 TNF IL5 IL1R1 ICOSLG CD8A CD4
49 poliomyelitis 30.6 TNF CD8A CD4
50 cryptococcal meningitis 30.6 CD8A CD4 CCR6

Graphical network of the top 20 diseases related to Cellulitis:



Diseases related to Cellulitis
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Symptoms & Phenotypes for Cellulitis

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UMLS symptoms related to Cellulitis:


fever, pruritus, exanthema

MGI Mouse Phenotypes related to Cellulitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 CAMP CCR6 CD4 CD8A CHI3L1 CYBB
2 immune system MP:0005387 9.73 CAMP CCR6 CD4 CD8A CHI3L1 CYBB
3 integument MP:0010771 9.28 ATP2C1 CD4 CD8A DSG1 DSG3 FLT4
Sources

Drugs & Therapeutics for Cellulitis

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Drugs for Cellulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 221)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefazolin Approved Phase 4 25953-19-9 656510 33255
2
Lincomycin Approved, Vet_approved Phase 4 154-21-2 656509
3
Tolnaftate Approved, Investigational, Vet_approved Phase 4 2398-96-1 5510
4
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
5
Lenograstim Approved, Investigational Phase 4 135968-09-1
6
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
7
Sargramostim Approved, Investigational Phase 4 83869-56-1, 123774-72-1
8
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
9
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
10
Cephalexin Approved, Investigational, Vet_approved Phase 4 15686-71-2 27447
11
Retapamulin Approved Phase 4 224452-66-8 6918462
12
Ceftaroline fosamil Approved, Investigational Phase 4 229016-73-3
13
Iodine Approved, Investigational Phase 4 7553-56-2 807
14
Povidone-iodine Approved Phase 4 25655-41-8
15
Povidone Approved Phase 4 9003-39-8
16
Vancomycin Approved Phase 4 1404-90-6 14969 441141
17
Dalbavancin Approved, Investigational Phase 4 171500-79-1, 91097-81-3 122186
18
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
19
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
20
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
21
Daptomycin Approved, Investigational Phase 4 103060-53-3 16129629
22
Cysteine Approved, Nutraceutical Phase 4 52-90-4 5862
23 Respiratory System Agents Phase 4
24 Antidotes Phase 4
25 Antioxidants Phase 4
26 Antiviral Agents Phase 4
27 Expectorants Phase 4
28 N-monoacetylcystine Phase 4
29 penicillins Phase 4
30 Clindamycin phosphate Phase 4
31 Clindamycin palmitate Phase 4
32 Vasoconstrictor Agents Phase 4
33 Hemostatics Phase 4
34 Vasopressins Phase 4
35 Arginine Vasopressin Phase 4
36 Coagulants Phase 4
37 Plasma Substitutes Phase 4
38 Blood Substitutes Phase 4
39 cadexomer iodine Phase 4
40 Antibiotics, Antitubercular Phase 4
41 Anti-Inflammatory Agents Phase 4
42 Pharmaceutical Solutions Phase 4
43 Antirheumatic Agents Phase 4
44 Anesthetics, Local Phase 4
45 Anti-Infective Agents, Local Phase 4
46 Ketorolac Tromethamine Phase 4
47 Analgesics Phase 4
48 Analgesics, Non-Narcotic Phase 4
49 Cyclooxygenase Inhibitors Phase 4
50 Anti-Inflammatory Agents, Non-Steroidal Phase 4

Interventional clinical trials:

(show top 50) (show all 228)
# Name Status NCT ID Phase Drugs
1 A Double Blind Randomised Control Trial to Measure the Effect of the Addition of Clindamycin to Flucloxacillin for the Treatment of Limb Cellulitis Unknown status NCT01876628 Phase 4 Flucloxacillin and Clindamycin;Flucloxacillin and placebo
2 Oral Flucloxacillin Alone Versus Flucloxacillin and Phenoxymethylpenicillin for the Emergency Department Outpatient Treatment of Cellulitis: a Non-inferiority Randomised Controlled Trial. Unknown status NCT02922686 Phase 4 Flucloxacillin;Phenoxymethylpenicillin;Placebo (for phenoxymethylpenicillin)
3 Double Blinded Prospective Randomized Controlled Trial Comparing Cefazolin Plus Vancomycin Versus Cefazolin Plus Daptomycin for Vascular Surgery Prophylaxis Unknown status NCT01612052 Phase 4 Antibiotic Prophylaxis
4 Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence Unknown status NCT02566928 Phase 4 2% mupirocin ointment
5 The Use of Antimicrobial Gauze in Pregnant Women Undergoing C-section With BMI >40 to Decrease Wound Complications by 6 Weeks postpartum--a Small Feasibility Study Unknown status NCT02882360 Phase 4
6 Granulocyte Colony Stimulating Factor Plus N-Acetyl Cysteine In Severe Alcoholic Hepatitis Unknown status NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
7 A Randomised Controlled Trial Comparing Bacteraemia Rates in Closed Luer Lock Access Devices(TEGO) With Standard Devices in the Outpatient Haemodialysis Population Unknown status NCT01082770 Phase 4
8 A Multicenter, Randomized Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in the Treatment of Cellulitis or Erysipelas Completed NCT00295178 Phase 4 Daptomycin;Vancomycin
9 Effects of Daptomycin in the Levels of IL-1, IL-6 and TNF in Patients With Complicated Cellulitis/Erisipela in Comparison With Vancomycin or Oxacillin Completed NCT01626560 Phase 4 Daptomycin;Vancomycin
10 Randomised Controlled Trial to Investigate Whether Prophylactic Antibiotics Can Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg (PATCH I) Completed NCT00552799 Phase 4 Penicillin VK
11 Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections Completed NCT01549613 Phase 4 Daptomycin;Vancomycin
12 An Open-Label, Non-Comparative Study to Assess the Pharmacokinetics, Safety and Efficacy of Topical Retapamulin (SB-275833) Ointment, 1%, Twice Daily for Five Days in the Treatment of Uncomplicated Skin and Skin Structure Infections in Pediatric Subjects Aged 2 to 24 Months Completed NCT00555061 Phase 4 Retapamulin Ointment, 1%
13 A Randomized Study to Evaluate Comparative Effectiveness, Inpatient Resource Utilization, and Cost of Daptomycin vs. Vancomycin in the Treatment of Patients With Complicated Skin and Skin Structure Infections Due to Suspected or Documented Methicillin-resistant Staphylococcus Aureus (MRSA) Completed NCT01419184 Phase 4 Daptomycin;Vancomycin
14 Clinical and Economic Outcomes of Ceftaroline Fosamil for the Treatment of Acute Bacterial Skin and Skin Structure Infections Documented or at Risk of Methicillin-Resistant S. Aureus Completed NCT02582203 Phase 4 Ceftaroline;Vancomycin
15 Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy Completed NCT00799292 Phase 4 Vasopressin
16 Randomized Clinical Trial of Wound Packing Following Incision and Drainage of Superficial Skin Abscesses in the Pediatric Emergency Department Completed NCT00746109 Phase 4
17 Skin and Soft Tissue Infection (SSTI) Study Completed NCT02600871 Phase 4 Provodine
18 Evaluation of Provase in the Post Burn Rehabilitation Population for Itch Control and Moisturization Properties Completed NCT00782054 Phase 4
19 Comparison of Cephalexin Versus Clindamycin in the Empiric, Outpatient Treatment of Suspected Staphylococcal Cutaneous Infections in the Era of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA) Completed NCT00352612 Phase 4 clindamycin;cephalexin
20 Prospective, Multicenter, Study Evaluating Vessel Sealing Utilizing the Harmonic ACE®+7 Shears During Total Laparoscopic Hysterectomy Completed NCT02278640 Phase 4
21 The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown Recruiting NCT03929224 Phase 4 Medicinal honey and bacitracin;Bacitracin
22 The Impact of the Continuous Infusion of Intraperitoneal Analgesics on Postoperative Pain After Minimally Invasive Hysterectomy: a Randomized Controlled Trial Recruiting NCT04130464 Phase 4 Ropivacaine Infusion from ON-Q Pump;Ropivacaine + Ketorolac Infusion from ON-Q Pump;Normal Saline Infusion from ON-Q Pump
23 Hospital Avoidance Strategies for Treatment of Acute Bacterial Skin and Skin Structure Infection (ABSSSI) Recruiting NCT03372941 Phase 4 Dalbavancin
24 Controlled, Multicenter, Randomized Parallel Group Pilot Study With 2 Treatment Arms in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis (BV) Recruiting NCT02042287 Phase 4 Metronidazole
25 Duration of Antibiotic Therapy for Cellulitis (DANCE): a Randomized Controlled Trial Comparing 6 to 12 Days of Antibiotic Therapy for Patients Hospitalized With Cellulitis Terminated NCT02032654 Phase 4 Flucloxacillin;Placebo (for flucloxacillin)
26 A Multicentre, Open Label, Uncontrolled Clinical Trial to Evaluate Efficacy and Safety of Daptomycin for the Treatment of Complicated Skin and Skin-Structure Infections (cSSTI) Caused by Methicillin-resistant Staphylococcus Aureus (MRSA) Terminated NCT00463801 Phase 4 Daptomycin
27 Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department Unknown status NCT00323219 Phase 3 Cefazolin and Moxifloxacin
28 A Pilot Randomized Controlled Trial Assessing the Effectiveness of Alcohol Swabs in Preventing Infections in Pediatric Patients Receiving Vaccinations Unknown status NCT03131843 Phase 3 Alcohol;No alcohol
29 A Multicenter, Randomized, Double Blind, Comparative Trial of Intravenous MERREM (Meropenem, ICI 194,660) vs PRIMAXIN I.V. (Imipenem-cilastatin) in the Treatment of Hospitalised Subjects With Complicated Skin and Skin Structure Infections. Completed NCT00619710 Phase 3 Meropenem;Imipenem-cilastatin
30 A Phase 3, Randomized, Double Blind, Multinational Trial of Intravenous Telavancin Versus Vancomycin for Treatment of Complicated Gram Positive Skin and Skin Structure Infections With a Focus on Patients With Infections Due to Methicillin-resistant Staphylococcus Aureus Completed NCT00091819 Phase 3 Telavancin;Vancomycin
31 An Open-label Extension Study to Assess Efficacy, Safety and Tolerability of Canakinumab and the Efficacy and Safety of Childhood Vaccinations in Patients With Cryopyrin Associated Periodic Syndromes (CAPS) Completed NCT01576367 Phase 3
32 A Phase 3, Randomized, Double-Blind, Double-Dummy Study to Compare the Efficacy and Safety of Dalbavancin to a Comparator Regiment (Vancomycin and Linezolid) for the Treatment of Acute Bacterial Skin and Skin Structure Infections Completed NCT01339091 Phase 3 Dalbavancin;Vancomycin / Linezolid
33 A One-year Open-label, Multicenter Trial to Assess Efficacy, Safety and Tolerability of Canakinumab (ACZ885) and the Efficacy and Safety of Childhood Vaccinations in Patients Aged 4 Years or Younger With Cryopyrin Associated Periodic Syndromes (CAPS) Completed NCT01302860 Phase 3 ACZ885
34 A Phase 3, Randomized, Double-Blind, Multinational Trial of Intravenous Telavancin Versus Vancomycin for Treatment of Complicated Gram Positive Skin and Skin Structure Infections With a Focus on Patients With Infections Due to Methicillin-resistant Staphylococcus Aureus Completed NCT00107978 Phase 3 Telavancin;Vancomycin
35 A Phase 3, Randomized, Double-Blind, Double-Dummy Study to Compare the Efficacy and Safety of Dalbavancin to a Comparator Regimen (Vancomycin and Linezolid) for the Treatment of Acute Bacterial Skin and Skin Structure Infections Completed NCT01431339 Phase 3 IV Dalbavancin;Vancomycin/Linezolid
36 A Phase 3b, Double-Blind, Multicenter, Randomized Study to Compare the Efficacy and Safety of Single Dose Dalbavancin to a Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Completed NCT02127970 Phase 3 Dalbavancin;Dalbavancin-matching Placebo
37 Clinical and Instrumental Evaluation of the Activity of a Pharmacological "Anticellulitis" Product vs. a Reference Product on the Market: Comparison Within Subjects (Double Blind Study) Completed NCT02195297 Phase 3
38 A Phase 3, Multicenter, Randomized, Double-blind, Active-controlled Study to Evaluate the Efficacy and Safety of Delafloxacin Compared With Vancomycin + Aztreonam in Patients With Acute Bacterial Skin and Skin Structure Infections Completed NCT01811732 Phase 3 Delafloxacin;Vancomycin;Aztreonam;Placebo
39 The Effects of Iontophoresis in Women With Gynoid Hidrolipodystrophy. Completed NCT03556917 Phase 2, Phase 3
40 Strategies Using Off-Patent Antibiotics for Methicillin-Resistant Staphylococcus Aureus ("STOP MRSA") - A Phase IIB, Multi-Center, Randomized, Double-Blind Clinical Trial Completed NCT00729937 Phase 2, Phase 3 Cephalexin;Clindamycin;Trimethoprim-sulfamethoxazole
41 A Multicenter, Active-Controlled, Randomized Study to Evaluate the Safety and Efficacy of Levofloxacin Versus Ciprofloxacin HCl in the Treatment of Mild to Moderate Skin and Skin Structure Infections in Adults Completed NCT00257036 Phase 2, Phase 3 levofloxacin
42 A Phase 3, Multicenter, Randomized, Double-blind, Comparative Study to Evaluate the Safety and Efficacy of Ceftaroline Versus Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin and Skin Structure Infection Completed NCT00424190 Phase 3 IV Vancomycin plus IV Aztreonam;Ceftaroline
43 A Phase 3, Multicenter, Randomized, Double-blind, Comparative Study to Evaluate the Safety and Efficacy of Ceftaroline Versus Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin and Skin Structure Infection (cSSSI) Completed NCT00423657 Phase 3 ceftaroline;vancomycin plus aztreonam;Placebo
44 Randomized Placebo-Controlled Trial of Bactrim on 7 Day Outcome in Emergency Department Patients With Uncomplicated Abscesses at Risk for Community Acquired Methicillin Resistant Staph Aureus Completed NCT00973765 Phase 3 bactrim;placebo
45 An Open-label, Efficacy and Safety Study of Canakinumab (Anti-interleukin-1β Monoclonal Antibody) Administered for 6 Months (24 Weeks) in Japanese Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease, Followed by an Extension Phase to Provide Canakinumab to Study Patients Until it is Approved and Marketed in Japan Completed NCT00991146 Phase 3 canakinumab
46 Ultrasound Guided Needle Drainage Versus Formal Incision and Drainage of Superficial Soft Tissue Abscesses in the Emergency Department Setting Completed NCT01085929 Phase 3
47 A Multicenter, Double-Blind, Randomized Study to Evaluate the Efficacy and Safety of Single-Dose IV Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection (SOLO II) Completed NCT01252732 Phase 3 Single-Dose IV Oritavancin Diphosphate;IV Vancomycin
48 A Multicenter, Double-Blind, Randomized Study to Evaluate the Efficacy and Safety of Single-Dose IV Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection (SOLO I) Completed NCT01252719 Phase 3 Single-Dose IV Oritavancin Diphosphate;IV Vancomycin
49 An Observer-blind, Multicenter, Non-inferiority, Comparative Study of the Safety and Efficacy of Topical 1% SB-275833 Ointment, Applied Twice Daily for 5 Days, Versus Topical 2% Fusidic Acid Cream Applied Three Times Daily for 7 Days in the Treatment Adult and Paediatric Subjects With Impetigo Completed NCT00133874 Phase 3 SB-275833 ointment, 1%
50 Evaluation of Novel Antimicrobial Hand Towels Completed NCT02512614 Phase 2, Phase 3

Search NIH Clinical Center for Cellulitis

Cochrane evidence based reviews: cellulitis

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Genetic Tests for Cellulitis

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Anatomical Context for Cellulitis

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MalaCards organs/tissues related to Cellulitis:

40
Skin, Breast, Bone, Lymph Node, Testes, Eye, T Cells
Sources

Publications for Cellulitis

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Articles related to Cellulitis:

(show top 50) (show all 8773)
# Title Authors PMID Year
1
Factors associated with sepsis development in 606 Spanish adult patients with cellulitis. 42 61
32164590 2020
2
What diagnostic strategies can help differentiate cellulitis from other causes of red legs in primary care? 42 61
32051117 2020
3
Follicular occlusion triad: an isotopic response or adverse effect of rituximab? 61 42
32239887 2020
4
Hereditary lymphedema type I associated with VEGFR3 mutation: the first de novo case and atypical presentations. 61 54
16965327 2006
5
Destructive domino: Subcutaneous self-implanted penile foreign body implicated in rule-out penile fracture. 61
32477880 2020
6
Orbital cellulitis, sinusitis and intracranial abnormalities in two adolescents with COVID-19. 61
32419568 2020
7
Eye-Related Emergency Department Visits and The Opioid Epidemic: a 10-Year Analysis. 61
32223491 2020
8
Antibiotic use and resistance: a nationwide questionnaire survey among French dentists. 61
32062724 2020
9
Laparoscopic-assisted Stamm-gastrostomy: technical modifications to ease suturing inside the minimal trocar site. 61
31720827 2020
10
Management of facial cellulitis of odontogenic origin in a paediatric hospital. 61
31894605 2020
11
Hand Cellulitis and Abscess From a Kinkajou Bite: a Case Report and Review of Kinkajou Bites in Humans. 61
31725116 2020
12
Incidence and treatment costs of severe bacterial infections among people who inject heroin: A cohort study in South London, England. 61
32422537 2020
13
Ultrasound Vibroelastography for Evaluation of Secondary Extremity Lymphedema: A Clinical Pilot Study. 61
32530852 2020
14
Evidence-based telehealth clinical pathway for pediatric tympanostomy tube otorrhea. 61
32251973 2020
15
Randomised clinical trial: palliative long-term abdominal drains vs large-volume paracentesis in refractory ascites due to cirrhosis. 61
32478917 2020
16
Three cases of fulminant cellulitis caused by non-O1, non-O139 Vibrio cholerae in Southern Finland. 61
32324089 2020
17
Kosaki overgrowth syndrome: A novel pathogenic variant in PDGFRB and expansion of the phenotype including cerebrovascular complications. 61
32291752 2020
18
Macrophomina phaseolina: an overlooked cutaneous infection, seed rot disease in humans. 61
31729754 2020
19
Ligaclip for Preauricular Skin Tags in the Newborn. 61
32512592 2020
20
Case Series and Review of the Literature of Mycobacterium chelonae Infections of the Lower Extremities. 61
32507603 2020
21
An Orbital Abscess Secondary to Intraoral Impalement. 61
32282484 2020
22
Clinicians need to consider surgery when presented with some markers for severe paediatric orbital cellulitis. 61
31803955 2020
23
[Pelvic cellulitis on pyogenic streptococcal bartholinitis: Case report]. 61
32112861 2020
24
Bilateral dacryocystitis complicated by unilateral retrobulbar abscess in a five-week-old infant. 61
31509038 2020
25
The management of periorbital cellulitis secondary to sinonasal infection: a multicenter prospective study in the United Kingdom. 61
32282127 2020
26
Patient preference for cellulitis treatment: at-home care is preferred to hospital-based treatment. 61
32531303 2020
27
Wells syndrome (eosinophilic cellulitis) following vaccination: Two pediatric cases with positive patch test to aluminium salts. 61
32034766 2020
28
Fibroblast Growth Factor 23 and Risk of Hospitalization with Infection in Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort (CRIC) Study. 61
32576601 2020
29
Simultaneous Ipsilateral Vascularized Lymph Node Transplantation and Contralateral Lymphovenous Anastomosis in Bilateral Extremity Lymphedema with Different Severities. 61
32556869 2020
30
Adverse events following immunization with the live-attenuated recombinant Japanese encephalitis vaccine (IMOJEV®) in Taiwan, 2017-18. 61
32546414 2020
31
Bacteremic cellulitis mimicking erythema nodosum caused by Streptococcus sanguinis endocarditis. 61
32516452 2020
32
A quasi-randomized clinical trial: virtual reality versus proprioceptive neuromuscular facilitation for postmastectomy lymphedema. 61
32537717 2020
33
[Cervicofacial cellulitis complicated by internal jugular vein thrombosis]. 61
32505376 2020
34
Comparing the Safety and Cost of Image-Guided Percutaneous Gastrostomy Tube Placement in the Outpatient Versus Overnight Observation Setting in a Single-Center Retrospective Study. 61
32527708 2020
35
DRESS syndrome in response to Denosumab: First documented case report. 61
31890758 2020
36
Long-Term Cilostazol Treatment and Predictive Factors on Outcomes of Endovascular Intervention in Patients with Diabetes Mellitus and Critical Limb Ischemia. 61
32564334 2020
37
Surgical interventions combined with photodynamic therapy in the treatment of Perifolliculitis Capitis Abscendens et Suffodiens: Report of 5 cases. 61
32109620 2020
38
Complicated skin and soft tissue infections in remote indigenous communities. 61
32537920 2020
39
Cellulitis-like Sweet Syndrome caused by adalimumab therapy for severe hidradenitis suppurativa. 61
32567672 2020
40
A rare etiology of preseptal cellulitis: Leishmaniasis. 61
32499106 2020
41
Upper extremity exertional rhabdomyolysis: MR imaging findings in four cases. 61
32346455 2020
42
Case Report: Treatment of Refractory Post-Surgical Neuralgia With Erector Spinae Plane Block. 61
31821708 2020
43
Nutritional Counseling Program for Morbidly Obese Patients Enables Weight Optimization for Safe Total Joint Arthroplasty. 61
32501522 2020
44
No-Scar Breast Reduction Utilizing Power-Assisted Liposuction Mammaplasty, Loops, and Lipofilling. 61
32520997 2020
45
Analysis of risk factors for dermatitis and cellulitis in turkeys using abattoir post mortem data. 61
32508148 2020
46
The Cumulative Effect of Substance Abuse Disorders and Depression on Postoperative Complications After Primary Total Knee Arthroplasty. 61
32061474 2020
47
Sterile granulomatous dermatitis and lymphadenitis (juvenile cellulitis) in adult dogs: a retrospective analysis of 90 cases (2004-2018). 61
31789433 2020
48
Imported recurrent cellulitis, the relevance of anamnesis. 61
32057554 2020
49
Cryptococcal Disease Presenting With Cellulitis in Kidney Transplant Recipients. 61
32532380 2020
50
Nail Wound and Cellulitis Following Typhoon Hagibis in Fukushima, Japan. 61
32487277 2020
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Variations for Cellulitis

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Expression for Cellulitis

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Search GEO for disease gene expression data for Cellulitis.
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Pathways for Cellulitis

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Pathways related to Cellulitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Innate Immune System 65
Show member pathways
 13.62 TNF SERPINA3 RNASE3 IL5 IL1R1 ICOSLG
2
PAK Pathway 63
Show member pathways
 13.09 TNF IL5 IL1R1 FLT4 CYBB CD4
3
Allograft rejection 1 36
Show member pathways
 12.65 TNF RNASE3 IL5 ICOSLG CD8A CD4
4
Defensins 65
Show member pathways
 12.1 RNASE3 DEFB4A CD4 CCR6 CAMP
5
NOD-like receptor signaling pathway 36
12.02 TNF DEFB4A CYBB CAMP
6
Hematopoietic Stem Cells and Lineage-specific Markers 64
11.72 TNF IL5 FLT3 CD8A CD4
7
Dendritic Cells Developmental Lineage Pathway 64
11.49 TNF FLT3 CD8A CD4
8
Hematopoietic cell lineage 36
11.43 TNF IL5 IL1R1 FLT3 CD8A CD4
9
Cytokines and Inflammatory Response 1
11.04 TNF IL5 CD4
10
Innate Lymphoid Cells Differentiation 64
11 TNF IL5 IL1R1 CD8A CD4 CCR6
Sources

GO Terms for Cellulitis

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Cellular components related to Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 10.17 TNF IL1R1 ICOSLG FLT4 FLT3 DST
2 plasma membrane GO:0005886 10.1 TNF IL1R1 ICOSLG FLT4 FLT3 DST
3 extracellular space GO:0005615 10.01 TNF SERPINA3 RNASE3 IL5 DEFB4A COL17A1
4 extracellular region GO:0005576 9.9 TNF SERPINA3 RNASE3 IL5 IL1R1 FLT4
5 external side of plasma membrane GO:0009897 9.43 TNF IL1R1 ICOSLG CD8A CD4 CCR6
6 hemidesmosome GO:0030056 9.37 DST COL17A1
7 integral component of plasma membrane GO:0005887 9.28 TNF IL1R1 FLT4 FLT3 CYBB COL17A1

Biological processes related to Cellulitis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.87 TNF RNASE3 DEFB4A CAMP
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.83 TNF FLT4 CHI3L1 CD4
3 positive regulation of protein phosphorylation GO:0001934 9.8 TNF FLT4 CD4 CAMP
4 cytokine-mediated signaling pathway GO:0019221 9.8 TNF IL5 IL1R1 FLT3 CD4
5 neutrophil degranulation GO:0043312 9.8 SERPINA3 RNASE3 DSG1 CYBB CHI3L1 CAMP
6 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.73 FLT4 FLT3 CD8A CD4
7 positive regulation of kinase activity GO:0033674 9.71 FLT4 FLT3 CD4
8 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.69 RNASE3 DEFB4A CAMP
9 defense response to Gram-positive bacterium GO:0050830 9.67 TNF RNASE3 DEFB4A CAMP
10 antimicrobial humoral response GO:0019730 9.65 RNASE3 DEFB4A CAMP
11 T cell activation GO:0042110 9.63 ICOSLG CD8A CD4
12 inflammatory response GO:0006954 9.63 TNF SERPINA3 IL5 IL1R1 CYBB CHI3L1
13 positive regulation of podosome assembly GO:0071803 9.56 TNF IL5
14 defense response to Gram-negative bacterium GO:0050829 9.56 RNASE3 DEFB4A CD4 CAMP
15 hemidesmosome assembly GO:0031581 9.55 DST COL17A1
16 defense response GO:0006952 9.35 TNF ICOSLG DEFB4A CYBB CAMP
17 immune response GO:0006955 9.17 TNF IL5 IL1R1 DEFB4A CD8A CD4

Molecular functions related to Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vascular endothelial growth factor-activated receptor activity GO:0005021 8.62 FLT4 FLT3
Sources

Sources for Cellulitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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