MCID: CNT027
MIFTS: 17

Central Nervous System Fibrosarcoma

Categories: Bone diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Central Nervous System Fibrosarcoma

MalaCards integrated aliases for Central Nervous System Fibrosarcoma:

Name: Central Nervous System Fibrosarcoma 12 15 71
Fibrosarcoma of the Cns 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6451
NCIt 49 C5465
UMLS 71 C1332879

Summaries for Central Nervous System Fibrosarcoma

MalaCards based summary : Central Nervous System Fibrosarcoma, also known as fibrosarcoma of the cns, is related to meningioma, radiation-induced and meningioma, familial. An important gene associated with Central Nervous System Fibrosarcoma is FOXK1 (Forkhead Box K1). Affiliated tissues include breast, bone and heart, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Central Nervous System Fibrosarcoma

Diseases related to Central Nervous System Fibrosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 56, show less)
# Related Disease Score Top Affiliating Genes
1 meningioma, radiation-induced 10.0
2 meningioma, familial 10.0
3 spinal meningioma 10.0
4 fibrosarcoma 10.0
5 secretory meningioma 10.0
6 lymphoplasmacyte-rich meningioma 10.0
7 speech disorder 10.0
8 cystadenofibroma 9.9 KRT7 FOXK1
9 angiosarcoma 9.8 KRT7 CD34
10 breast hemangiopericytoma 9.8 KRT7 CD34
11 nephrogenic adenofibroma 9.8 KRT7 CD34
12 fibroma 9.8 KRT7 CD34
13 aortic malignant tumor 9.8 KRT7 CD34
14 colonic lymphangioma 9.8 KRT7 CD34
15 jejunal neoplasm 9.8 KRT7 CD34
16 metatypical basal cell carcinoma 9.8 KRT7 CD34
17 basal cell carcinoma 9.8 KRT7 CD34
18 liver sarcoma 9.8 KRT7 CD34
19 benign mesothelioma 9.8 KRT7 CD34
20 benign mesenchymoma 9.8 KRT7 CD34
21 sarcomatous intrahepatic cholangiocarcinoma 9.8 KRT7 CD34
22 bladder leiomyoma 9.8 KRT7 CD34
23 pulmonary artery leiomyosarcoma 9.8 KRT7 CD34
24 mucinous tubular and spindle renal cell carcinoma 9.8 KRT7 CD34
25 adenoid squamous cell carcinoma 9.8 KRT7 CD34
26 breast leiomyosarcoma 9.8 KRT7 CD34
27 mediastinal cancer 9.8 KRT7 CD34
28 uterus leiomyosarcoma 9.8 KRT7 CD34
29 central epithelioid sarcoma 9.8 KRT7 CD34
30 epithelioid sarcoma 9.8 KRT7 CD34
31 vulvar proximal-type epithelioid sarcoma 9.7 KRT7 CD34
32 adult mesoblastic nephroma 9.7 KRT7 CD34
33 heart cancer 9.7 KRT7 CD34
34 monophasic synovial sarcoma 9.7 KRT7 CD34
35 conventional angiosarcoma 9.7 FOXK1 CD34
36 epithelioid cell synovial sarcoma 9.7 KRT7 CD34
37 sweat gland neoplasm 9.7 KRT7 CD34
38 vulvar disease 9.7 KRT7 CD34
39 spindle cell sarcoma 9.7 KRT7 CD34
40 thoracic benign neoplasm 9.7 KRT7 CD34
41 breast benign neoplasm 9.7 KRT7 CD34
42 respiratory system benign neoplasm 9.7 KRT7 CD34
43 well-differentiated liposarcoma 9.7 KRT7 CD34
44 cardiovascular cancer 9.7 KRT7 CD34
45 vascular cancer 9.7 KRT7 CD34
46 mixed cell type cancer 9.7 KRT7 CD34
47 synovium cancer 9.6 KRT7 CD34
48 spindle cell carcinoma 9.6 KRT7 CD34
49 cavernous hemangioma 9.6 KRT7 CD34
50 hemangioma 9.6 KRT7 CD34
51 intestinal obstruction 9.6 KRT7 CD34
52 cell type benign neoplasm 9.5 KRT7 CD34
53 sarcoma, synovial 9.5 KRT7 CD34
54 malignant peripheral nerve sheath tumor 9.4 KRT7 CD34
55 thyroid angiosarcoma 9.3 KRT7 FOXK1 CD34
56 wilms tumor 1 9.2 KRT7 CD34

Graphical network of the top 20 diseases related to Central Nervous System Fibrosarcoma:



Diseases related to Central Nervous System Fibrosarcoma

Symptoms & Phenotypes for Central Nervous System Fibrosarcoma

GenomeRNAi Phenotypes related to Central Nervous System Fibrosarcoma according to GeneCards Suite gene sharing:

26 (showing 7, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.5 CD34
2 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.5 FOXK1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.5 CD34
4 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.5 FOXK1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.5 FOXK1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.5 CD34 FOXK1
7 Reduced mammosphere formation GR00396-S 8.8 CD34 FOXK1 KRT7

Drugs & Therapeutics for Central Nervous System Fibrosarcoma

Search Clinical Trials , NIH Clinical Center for Central Nervous System Fibrosarcoma

Genetic Tests for Central Nervous System Fibrosarcoma

Anatomical Context for Central Nervous System Fibrosarcoma

MalaCards organs/tissues related to Central Nervous System Fibrosarcoma:

40
Breast, Bone, Heart, Colon, Liver, Thyroid, Uterus

Publications for Central Nervous System Fibrosarcoma

Articles related to Central Nervous System Fibrosarcoma:

(showing 1, show less)
# Title Authors PMID Year
1
Primary Central Nervous System Fibrosarcoma. 61
28936084 2017

Variations for Central Nervous System Fibrosarcoma

Expression for Central Nervous System Fibrosarcoma

Search GEO for disease gene expression data for Central Nervous System Fibrosarcoma.

Pathways for Central Nervous System Fibrosarcoma

GO Terms for Central Nervous System Fibrosarcoma

Sources for Central Nervous System Fibrosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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