MCID: CNT042
MIFTS: 20

Central Nervous System Mesenchymal Non-Meningothelial Tumor

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Central Nervous System Mesenchymal Non-Meningothelial Tumor

MalaCards integrated aliases for Central Nervous System Mesenchymal Non-Meningothelial Tumor:

Name: Central Nervous System Mesenchymal Non-Meningothelial Tumor 12 15
Central Nervous System Mesenchymal Non-Meningothelial Tumour 12
Non-Meningothelial Mesenchymal Tumour 12
Non-Meningothelial Mesenchymal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:502

Summaries for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Disease Ontology : 12 A central nervous system cancer that is characterized by mesenchymal tumors within the CNS that develops from meninges, has material basis in abnormally proliferating cells derives from mesoderm.

MalaCards based summary : Central Nervous System Mesenchymal Non-Meningothelial Tumor, also known as central nervous system mesenchymal non-meningothelial tumour, is related to myocardium cancer and kidney cortex disease. An important gene associated with Central Nervous System Mesenchymal Non-Meningothelial Tumor is MYOG (Myogenin), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Myogenesis. Related phenotype is respiratory system.

Related Diseases for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Diseases related to Central Nervous System Mesenchymal Non-Meningothelial Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 myocardium cancer 10.3 MYOG CD99
2 kidney cortex disease 10.2 NUTM2B MYOG
3 extraskeletal mesenchymal chondrosarcoma 10.2 EWSR1 CD99
4 kidney sarcoma 10.2 NUTM2E NUTM2B
5 skeletal muscle neoplasm 10.2 MYOG MYOD1
6 prostate embryonal rhabdomyosarcoma 10.2 MYOG MYOD1
7 undifferentiated embryonal sarcoma of the liver 10.2 MYOG MYOD1
8 pulmonary vein leiomyosarcoma 10.2 MYOD1 CD99
9 embryonal sarcoma 10.2 MYOG MYOD1
10 gallbladder sarcoma 10.2 MYOG MYOD1
11 prostate rhabdomyosarcoma 10.2 MYOG MYOD1
12 adult fibrosarcoma 10.2 MYOG MYOD1
13 malignant triton tumor 10.2 MYOG MYOD1
14 kidney fibrosarcoma 10.1 EWSR1 CD99
15 childhood malignant schwannoma 10.1 MYOG EWSR1
16 epithelioid cell synovial sarcoma 10.1 EWSR1 CD99
17 prostate stromal sarcoma 10.1 MYOG MYOD1
18 malignant mesenchymoma 10.1 MYOG MYOD1
19 pediatric fibrosarcoma 10.1 MYOG EWSR1
20 cervical adenosarcoma 10.1 MYOG MYOD1
21 congenital fibrosarcoma 10.1 MYOG EWSR1
22 conventional central osteosarcoma 10.1 EWSR1 CD99
23 gliofibroma 10.1 MYOD1 CD99
24 mesenchymal cell neoplasm 10.1 MYOG EWSR1
25 gas gangrene 10.1 MYOG MYOD1
26 bladder leiomyoma 10.0 MYOD1 EWSR1
27 well-differentiated liposarcoma 10.0 MYOG EWSR1
28 endometrial stromal tumor 10.0 NUTM2B EWSR1
29 spindle cell sarcoma 10.0 MYOG EWSR1
30 emery-dreifuss muscular dystrophy 2, autosomal dominant 10.0 MYOG MYOD1
31 orbit embryonal rhabdomyosarcoma 10.0 PAX7 PAX3 MYOG
32 parameningeal embryonal rhabdomyosarcoma 10.0 PAX7 PAX3 MYOG
33 botryoid rhabdomyosarcoma 10.0 PAX3 MYOG MYOD1
34 clear cell basal cell carcinoma 10.0 PAX7 PAX3 MYOG
35 spindle cell rhabdomyosarcoma 10.0 PAX3 MYOG MYOD1
36 myoblastoma 10.0 MYOG ENO2
37 cerebellopontine angle primitive neuroectodermal tumor 10.0 ENO2 CD99
38 endobronchial leiomyoma 10.0 MYOG ENO2
39 uterus leiomyosarcoma 10.0 MYOG ENO2
40 myxofibrosarcoma 10.0 MYOG EWSR1
41 central nervous system primitive neuroectodermal neoplasm 9.9 ENO2 CD99
42 rhabdoid cancer 9.9 MYOG MYOD1 EWSR1
43 malignant teratoma 9.9 ENO2 CD99
44 melanotic neuroectodermal tumor 9.9 MYOG ENO2
45 malignant fibrous histiocytoma 9.9 MYOG MYOD1 EWSR1
46 fibrous histiocytoma 9.9 EWSR1 ENO2
47 cauda equina neoplasm 9.9 EWSR1 ENO2
48 conventional leiomyosarcoma 9.9 PAX7 MYOG MYOD1
49 inflammatory leiomyosarcoma 9.9 PAX7 MYOG MYOD1
50 mixed cell type cancer 9.9 MYOG ENO2

Graphical network of the top 20 diseases related to Central Nervous System Mesenchymal Non-Meningothelial Tumor:



Diseases related to Central Nervous System Mesenchymal Non-Meningothelial Tumor

Symptoms & Phenotypes for Central Nervous System Mesenchymal Non-Meningothelial Tumor

MGI Mouse Phenotypes related to Central Nervous System Mesenchymal Non-Meningothelial Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.02 ENO2 MYOD1 MYOG PAX3 PAX7

Drugs & Therapeutics for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Search Clinical Trials , NIH Clinical Center for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Genetic Tests for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Anatomical Context for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Publications for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Variations for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Expression for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Search GEO for disease gene expression data for Central Nervous System Mesenchymal Non-Meningothelial Tumor.

Pathways for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Pathways related to Central Nervous System Mesenchymal Non-Meningothelial Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 PAX7 PAX3 EWSR1
2
Show member pathways
11.02 MYOG MYOD1
3 10.9 PAX3 MYOD1
4 10.9 PAX7 PAX3 MYOG MYOD1

GO Terms for Central Nervous System Mesenchymal Non-Meningothelial Tumor

Biological processes related to Central Nervous System Mesenchymal Non-Meningothelial Tumor according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.89 PAX7 PAX3 MYOG MYOD1 EWSR1
2 skeletal muscle tissue development GO:0007519 9.52 MYOG MYOD1
3 skeletal muscle cell differentiation GO:0035914 9.51 MYOG MYOD1
4 cellular response to estradiol stimulus GO:0071392 9.48 MYOG MYOD1
5 positive regulation of muscle cell differentiation GO:0051149 9.46 MYOG MYOD1
6 skeletal muscle fiber development GO:0048741 9.43 MYOG MYOD1
7 skeletal muscle tissue regeneration GO:0043403 9.4 MYOG MYOD1
8 positive regulation of myoblast differentiation GO:0045663 9.37 MYOG MYOD1
9 myoblast differentiation GO:0045445 9.32 MYOG MYOD1
10 myotube differentiation GO:0014902 9.26 MYOG MYOD1
11 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOG MYOD1
12 muscle cell fate commitment GO:0042693 8.96 MYOG MYOD1
13 muscle organ development GO:0007517 8.92 PAX7 PAX3 MYOG MYOD1

Molecular functions related to Central Nervous System Mesenchymal Non-Meningothelial Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity GO:0003700 9.26 PAX7 PAX3 MYOG MYOD1
2 E-box binding GO:0070888 9.16 MYOG MYOD1
3 sequence-specific double-stranded DNA binding GO:1990837 8.92 PAX7 PAX3 MYOG MYOD1

Sources for Central Nervous System Mesenchymal Non-Meningothelial Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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