MCID: CNT044
MIFTS: 22

Central Nervous System Primitive Neuroectodermal Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Central Nervous System Primitive Neuroectodermal Neoplasm

MalaCards integrated aliases for Central Nervous System Primitive Neuroectodermal Neoplasm:

Name: Central Nervous System Primitive Neuroectodermal Neoplasm 12 15
Cpnet 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0060103
UMLS 73 C3887678

Summaries for Central Nervous System Primitive Neuroectodermal Neoplasm

MalaCards based summary : Central Nervous System Primitive Neuroectodermal Neoplasm, also known as cpnet, is related to adult central nervous system primitive neuroectodermal neoplasm and childhood central nervous system primitive neuroectodermal neoplasm. An important gene associated with Central Nervous System Primitive Neuroectodermal Neoplasm is LIN28A (Lin-28 Homolog A), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotypes are behavior/neurological and nervous system

Related Diseases for Central Nervous System Primitive Neuroectodermal Neoplasm

Diseases in the Central Nervous System Primitive Neuroectodermal Neoplasm family:

Adult Central Nervous System Primitive Neuroectodermal Neoplasm

Diseases related to Central Nervous System Primitive Neuroectodermal Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)
# Related Disease Score Top Affiliating Genes
1 adult central nervous system primitive neuroectodermal neoplasm 12.4
2 childhood central nervous system primitive neuroectodermal neoplasm 12.4
3 embryoma 10.6 DICER1 SYP
4 ureter small cell carcinoma 10.5 ENO2 SYP
5 malignant sertoli cell tumor 10.5 ENO2 SYP
6 urinary bladder small cell neuroendocrine carcinoma 10.5 ENO2 SYP
7 auditory system cancer 10.5 ENO2 SYP
8 sinonasal undifferentiated carcinoma 10.5 ENO2 SYP
9 sensory organ benign neoplasm 10.5 ENO2 SYP
10 gallbladder small cell carcinoma 10.5 ENO2 SYP
11 atypical choroid plexus papilloma 10.5 DICER1 SYP
12 pancreatic somatostatinoma 10.5 ENO2 SYP
13 cutaneous ganglioneuroma 10.5 ENO2 SYP
14 extrahepatic bile duct adenocarcinoma 10.5 ENO2 SYP
15 small cell carcinoma of the bladder 10.5 ENO2 SYP
16 papillary tumor of the pineal region 10.5 ENO2 SYP
17 orbital cancer 10.5 ENO2 SYP
18 middle ear adenoma 10.5 ENO2 SYP
19 ovarian carcinosarcoma 10.5 ENO2 SYP
20 pulmonary large cell neuroendocrine carcinoma 10.5 ENO2 SYP
21 olfactory nerve neoplasm 10.5 ENO2 SYP
22 cauda equina neoplasm 10.5 ENO2 SYP
23 extraosseous chondrosarcoma 10.5 ENO2 SYP
24 malignant teratoma 10.5 ENO2 SYP
25 endometrial small cell carcinoma 10.5 ENO2 SYP
26 nodular ganglioneuroblastoma 10.5 ENO2 SYP
27 mucinous ovarian cystadenoma 10.5 ENO2 SYP
28 respiratory system benign neoplasm 10.5 ENO2 SYP
29 angiomyoma 10.5 ENO2 SYP
30 gastric squamous cell carcinoma 10.5 ENO2 SYP
31 gastric small cell carcinoma 10.5 ENO2 SYP
32 desmoplastic infantile ganglioglioma 10.5 GFAP SYP
33 extraventricular neurocytoma 10.5 GFAP SYP
34 desmoplastic small round cell tumor 10.5 ENO2 SYP
35 lung combined type small cell carcinoma 10.5 GFAP SYP
36 carcinoid tumors, intestinal 10.5 ENO2 SYP
37 bone benign neoplasm 10.5 ENO2 SYP
38 cervical clear cell adenocarcinoma 10.4 ENO2 SYP
39 extraskeletal ewing sarcoma 10.4 ENO2 SYP
40 gangliocytoma 10.4 GFAP SYP
41 rhabdoid meningioma 10.4 GFAP SYP
42 pilomyxoid astrocytoma 10.4 GFAP SYP
43 chordoid meningioma 10.4 GFAP SYP
44 chiari malformation 10.4 GFAP SYP
45 connective tissue benign neoplasm 10.4 ENO2 SYP
46 intraocular retinoblastoma 10.4 ENO2 SYP
47 sclerosing hemangioma 10.4 ENO2 SYP
48 intracranial cysts 10.4 ENO2 GFAP
49 angiocentric glioma 10.4 GFAP SYP
50 carcinoid syndrome 10.4 ENO2 SYP

Graphical network of the top 20 diseases related to Central Nervous System Primitive Neuroectodermal Neoplasm:



Diseases related to Central Nervous System Primitive Neuroectodermal Neoplasm

Symptoms & Phenotypes for Central Nervous System Primitive Neuroectodermal Neoplasm

MGI Mouse Phenotypes related to Central Nervous System Primitive Neuroectodermal Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.63 SYP TP53 DICER1 ENO2 GFAP LIN28A
2 nervous system MP:0003631 9.43 SYP TP53 DICER1 ENO2 GFAP LIN28A
3 normal MP:0002873 9.02 SYP TP53 DICER1 GFAP LIN28A

Drugs & Therapeutics for Central Nervous System Primitive Neuroectodermal Neoplasm

Search Clinical Trials , NIH Clinical Center for Central Nervous System Primitive Neuroectodermal Neoplasm

Genetic Tests for Central Nervous System Primitive Neuroectodermal Neoplasm

Anatomical Context for Central Nervous System Primitive Neuroectodermal Neoplasm

Publications for Central Nervous System Primitive Neuroectodermal Neoplasm

Variations for Central Nervous System Primitive Neuroectodermal Neoplasm

Expression for Central Nervous System Primitive Neuroectodermal Neoplasm

Search GEO for disease gene expression data for Central Nervous System Primitive Neuroectodermal Neoplasm.

Pathways for Central Nervous System Primitive Neuroectodermal Neoplasm

Pathways related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 ENO2 GFAP SYP
2 10.7 GFAP NES SYP

GO Terms for Central Nervous System Primitive Neuroectodermal Neoplasm

Cellular components related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.62 GFAP NES

Biological processes related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gene silencing by RNA GO:0031047 9.16 DICER1 LIN28A
2 miRNA metabolic process GO:0010586 8.96 DICER1 LIN28A
3 pre-miRNA processing GO:0031054 8.62 DICER1 LIN28A

Molecular functions related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 SYP TP53

Sources for Central Nervous System Primitive Neuroectodermal Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
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62 PubMed
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69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
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74 UMLS via Orphanet
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