MCID: CNT021
MIFTS: 17

Central Nervous System Rhabdomyosarcoma

Categories: Cancer diseases, Muscle diseases, Neuronal diseases

Aliases & Classifications for Central Nervous System Rhabdomyosarcoma

MalaCards integrated aliases for Central Nervous System Rhabdomyosarcoma:

Name: Central Nervous System Rhabdomyosarcoma 12 15 71
Rhabdomyosarcoma of the Cns 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4048
NCIt 50 C5464
UMLS 71 C1332891

Summaries for Central Nervous System Rhabdomyosarcoma

MalaCards based summary : Central Nervous System Rhabdomyosarcoma, also known as rhabdomyosarcoma of the cns, is related to rhabdomyosarcoma and orbit embryonal rhabdomyosarcoma. An important gene associated with Central Nervous System Rhabdomyosarcoma is PAX3 (Paired Box 3), and among its related pathways/superpathways are Mesodermal Commitment Pathway and Transcriptional misregulation in cancer. Related phenotypes are neoplasm and no phenotypic analysis

Related Diseases for Central Nervous System Rhabdomyosarcoma

Graphical network of the top 20 diseases related to Central Nervous System Rhabdomyosarcoma:



Diseases related to Central Nervous System Rhabdomyosarcoma

Symptoms & Phenotypes for Central Nervous System Rhabdomyosarcoma

MGI Mouse Phenotypes related to Central Nervous System Rhabdomyosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.13 FOXO1 MGMT PAX3
2 no phenotypic analysis MP:0003012 8.8 FOXO1 MGMT PAX3

Drugs & Therapeutics for Central Nervous System Rhabdomyosarcoma

Search Clinical Trials , NIH Clinical Center for Central Nervous System Rhabdomyosarcoma

Genetic Tests for Central Nervous System Rhabdomyosarcoma

Anatomical Context for Central Nervous System Rhabdomyosarcoma

Publications for Central Nervous System Rhabdomyosarcoma

Articles related to Central Nervous System Rhabdomyosarcoma:

# Title Authors PMID Year
1
Primary intraventricular central nervous system rhabdomyosarcoma. 61
25444091 2015
2
DNA repair alterations in common pediatric malignancies. 61
18160950 2008

Variations for Central Nervous System Rhabdomyosarcoma

Expression for Central Nervous System Rhabdomyosarcoma

Search GEO for disease gene expression data for Central Nervous System Rhabdomyosarcoma.

Pathways for Central Nervous System Rhabdomyosarcoma

Pathways related to Central Nervous System Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.64 PAX3 FOXO1
2 11.24 PAX3 FOXO1
3 10.67 MGMT FOXO1

GO Terms for Central Nervous System Rhabdomyosarcoma

Biological processes related to Central Nervous System Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to oxidative stress GO:0034599 8.62 MGMT FOXO1

Molecular functions related to Central Nervous System Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 8.8 PAX3 MGMT FOXO1

Sources for Central Nervous System Rhabdomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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