MCID: CNT108
MIFTS: 16

Central Polydactyly

Categories: Bone diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Central Polydactyly

MalaCards integrated aliases for Central Polydactyly:

Name: Central Polydactyly 59
Mesoaxial Polydactyly 59

Classifications:



External Ids:

Orphanet 59 ORPHA295004
UMLS via Orphanet 74 C0431903
ICD10 via Orphanet 34 Q69.0

Summaries for Central Polydactyly

MalaCards based summary : Central Polydactyly, also known as mesoaxial polydactyly, is related to split-foot malformation with mesoaxial polydactyly and pallister-hall syndrome. An important gene associated with Central Polydactyly is CPLANE1 (Ciliogenesis And Planar Polarity Effector 1). Affiliated tissues include bone.

Related Diseases for Central Polydactyly

Diseases in the Polydactyly family:

Central Polydactyly

Diseases related to Central Polydactyly via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 split-foot malformation with mesoaxial polydactyly 12.6
2 pallister-hall syndrome 11.6
3 holzgreve syndrome 11.3
4 bardet-biedl syndrome 17 11.3
5 orofaciodigital syndrome vi 11.1
6 polydactyly 10.3
7 bardet-biedl syndrome 2 10.2
8 bardet-biedl syndrome 10 10.2
9 bardet-biedl syndrome 11 10.2
10 bardet-biedl syndrome 12 10.2
11 bardet-biedl syndrome 10.2
12 holt-oram syndrome 9.9
13 chromosome 2q35 duplication syndrome 9.8

Graphical network of the top 20 diseases related to Central Polydactyly:



Diseases related to Central Polydactyly

Symptoms & Phenotypes for Central Polydactyly

Drugs & Therapeutics for Central Polydactyly

Search Clinical Trials , NIH Clinical Center for Central Polydactyly

Genetic Tests for Central Polydactyly

Anatomical Context for Central Polydactyly

MalaCards organs/tissues related to Central Polydactyly:

41
Bone

Publications for Central Polydactyly

Articles related to Central Polydactyly:

(show all 13)
# Title Authors Year
1
Isolated heptadactylia: A case report of central polydactyly of the foot. ( 29049244 )
2017
2
Central Polydactyly of the Foot: Surgical Management With Plantar and Dorsal Advancement Flaps. ( 24045588 )
2013
3
Mesoaxial polydactyly is a major feature in Bardet-Biedl syndrome patients with LZTFL1 (BBS17) mutations. ( 23692385 )
2013
4
[Clinical implication of residual mesoaxial polydactyly of the foot--case report]. ( 22519282 )
2011
5
Occurrence of central polydactyly, syndactyly, and cleft hand in a single family: report of five hands in three cases. ( 19762166 )
2009
6
Busulfan-induced central polydactyly, syndactyly and cleft hand or foot: a common mechanism of disruption leads to divergent phenotypes. ( 17661743 )
2007
7
Early morphological changes leading to central polydactyly, syndactyly, and central deficiencies: an experimental study in rats. ( 17996777 )
2007
8
An unusual and nonclassified central polydactyly of the foot. ( 15211207 )
2004
9
Holt-Oram syndrome with associated postaxial and central polydactyly. Further evidence for genetic heterogeneity in the Holt-Oram syndrome. ( 8985738 )
1996
10
Holt-Oram syndrome: postaxial and central polydactyly as variable manifestations in a four generations family. ( 8110414 )
1993
11
Cleft hand and central polydactyly in identical twins: a case report. ( 6685742 )
1983
12
Central polydactyly--a review of 12 cases and their surgical treatment. ( 7130654 )
1982
13
Treatment of central polydactyly. ( 4322173 )
1971

Variations for Central Polydactyly

Expression for Central Polydactyly

Search GEO for disease gene expression data for Central Polydactyly.

Pathways for Central Polydactyly

GO Terms for Central Polydactyly

Sources for Central Polydactyly

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....