MCID: CRB022
MIFTS: 40

Cerebellar Liponeurocytoma

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Cerebellar Liponeurocytoma

MalaCards integrated aliases for Cerebellar Liponeurocytoma:

Name: Cerebellar Liponeurocytoma 12 53 59 15 73
Lipomatous Medulloblastoma 12
Central Neurocytoma 73

Characteristics:

Orphanet epidemiological data:

59
cerebellar liponeurocytoma
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:6458
NCIt 50 C6905
Orphanet 59 ORPHA251931
UMLS via Orphanet 74 C1370507

Summaries for Cerebellar Liponeurocytoma

MalaCards based summary : Cerebellar Liponeurocytoma, also known as lipomatous medulloblastoma, is related to oligodendroglioma and medulloblastoma, and has symptoms including vomiting and headache. An important gene associated with Cerebellar Liponeurocytoma is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Wnt Signaling Pathways: beta-Catenin-dependent Wnt Signaling. Affiliated tissues include lung, brain and kidney, and related phenotypes are Decreased viability in esophageal squamous lineage and Increased proliferation

Related Diseases for Cerebellar Liponeurocytoma

Diseases related to Cerebellar Liponeurocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 199)
# Related Disease Score Top Affiliating Genes
1 oligodendroglioma 29.7 ENO2 GFAP OLIG2 SYP TP53
2 medulloblastoma 29.3 ATOH1 ENO2 GFAP MAP2 PTCH1 SMARCB1
3 gangliocytoma 10.3 RBFOX3 SYP
4 sella turcica neoplasm 10.3 RBFOX3 SYP
5 rosette-forming glioneuronal tumor 10.3 MAP2 SYP
6 bone benign neoplasm 10.3 ENO2 SYP
7 mucinous ovarian cystadenoma 10.3 ENO2 SYP
8 tuberculum sellae meningioma 10.3 RBFOX3 SYP
9 orbital cancer 10.3 ENO2 SYP
10 angiomyoma 10.3 ENO2 SYP
11 cervical clear cell adenocarcinoma 10.3 ENO2 SYP
12 middle ear adenoma 10.3 ENO2 SYP
13 endometrial small cell carcinoma 10.3 ENO2 SYP
14 prostate small cell carcinoma 10.3 ENO2 SYP
15 desmoplastic small round cell tumor 10.3 ENO2 SYP
16 extraskeletal ewing sarcoma 10.3 ENO2 SYP
17 medulloepithelioma 10.3 GFAP SYP
18 anaplastic ependymoma 10.3 GFAP SYP
19 angiocentric glioma 10.3 GFAP SYP
20 hemimegalencephaly 10.3 GFAP MAP2
21 cerebellar medulloblastoma 10.3 ENO2 GFAP
22 plexiform schwannoma 10.3 ENO2 GFAP
23 microcystic meningioma 10.3 ENO2 GFAP
24 panophthalmitis 10.3 SAG SYP
25 carotid body cancer 10.3 ENO2 SYP
26 cancer-associated retinopathy 10.3 ENO2 SAG
27 malignant sertoli cell tumor 10.3 ENO2 SYP
28 kidney rhabdoid cancer 10.2 ENO2 SMARCB1
29 desmoplastic infantile ganglioglioma 10.2 GFAP SYP
30 extraventricular neurocytoma 10.2 GFAP SYP
31 sinonasal undifferentiated carcinoma 10.2 ENO2 SYP
32 papillary tumor of the pineal region 10.2 ENO2 MAP2 SYP
33 partial motor epilepsy 10.2 RBFOX3 SYP
34 lung combined type small cell carcinoma 10.2 GFAP SYP
35 rhabdoid meningioma 10.2 GFAP SMARCB1
36 intracranial cysts 10.2 ENO2 GFAP
37 ependymoma 10.2 ENO2 GFAP SYP
38 primitive neuroectodermal tumor of the cervix uteri 10.2 ENO2 GFAP
39 chiari malformation 10.2 GFAP MAP2 SYP
40 dysembryoplastic neuroepithelial tumor 10.2 GFAP MAP2 SYP
41 pancreatic serous cystadenoma 10.2 CHGA SYP
42 conventional angiosarcoma 10.2 CHGA SYP
43 pulmonary sclerosing hemangioma 10.2 CHGA SYP
44 pancreatoblastoma 10.2 CHGA SYP
45 non-functioning pancreatic endocrine tumor 10.2 CHGA SYP
46 clear cell ependymoma 10.2 ENO2 GFAP SYP
47 subependymal glioma 10.2 ENO2 GFAP SYP
48 astroblastoma 10.2 ENO2 GFAP SYP
49 melanotic neuroectodermal tumor 10.2 ENO2 GFAP SYP
50 acute thyroiditis 10.2 CHGA ENO2

Graphical network of the top 20 diseases related to Cerebellar Liponeurocytoma:



Diseases related to Cerebellar Liponeurocytoma

Symptoms & Phenotypes for Cerebellar Liponeurocytoma

UMLS symptoms related to Cerebellar Liponeurocytoma:


vomiting, headache

GenomeRNAi Phenotypes related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.61 ATOH1 CHGA FABP4 GFAP MAP2 NEUROG1
2 Increased proliferation GR00094-A 8.62 SMARCB1 TP53

MGI Mouse Phenotypes related to Cerebellar Liponeurocytoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.2 ATOH1 ENO2 GFAP MAP2 NEUROG1 OLIG2
2 growth/size/body region MP:0005378 10.14 CHGA ENO2 FABP4 GFAP MAP2 OLIG2
3 cellular MP:0005384 10.09 ATOH1 ENO2 FABP4 GFAP NEUROG1 OLIG2
4 homeostasis/metabolism MP:0005376 10.07 ATOH1 CHGA FABP4 GFAP PLIN1 PTCH1
5 mortality/aging MP:0010768 10.06 ATOH1 CHGA FABP4 GFAP MAP2 NEUROG1
6 nervous system MP:0003631 9.97 ATOH1 CHGA ENO2 GFAP MAP2 NEUROG1
7 muscle MP:0005369 9.86 CHGA FABP4 GFAP OLIG2 PLIN1 PTCH1
8 no phenotypic analysis MP:0003012 9.5 ATOH1 CHGA NEUROG1 OLIG2 PTCH1 SUFU
9 vision/eye MP:0005391 9.17 GFAP OLIG2 PTCH1 SAG SMARCB1 SUFU

Drugs & Therapeutics for Cerebellar Liponeurocytoma

Search Clinical Trials , NIH Clinical Center for Cerebellar Liponeurocytoma

Genetic Tests for Cerebellar Liponeurocytoma

Anatomical Context for Cerebellar Liponeurocytoma

MalaCards organs/tissues related to Cerebellar Liponeurocytoma:

41
Lung, Brain, Kidney, Bone, Ovary, Cervix, Pineal

Publications for Cerebellar Liponeurocytoma

Articles related to Cerebellar Liponeurocytoma:

(show all 45)
# Title Authors Year
1
Supratentorial intracerebral cerebellar liponeurocytoma: A case report and literature review. ( 29480846 )
2018
2
Cerebellar liponeurocytoma - a rare entity: a case report. ( 29908563 )
2018
3
Cerebellar Liponeurocytoma: The Dilemma of Multifocality. ( 30172975 )
2018
4
Clinical course of the untreated calcified big cerebellar liponeurocytoma. ( 30483397 )
2018
5
Cerebellar liponeurocytoma presenting as multifocal bilateral cerebellar hemispheric mass lesions. ( 28290424 )
2017
6
Cerebellar liponeurocytoma with atypical histological features - a rare example of a glioneuronal tumor. ( 28984116 )
2017
7
Cerebellar Liponeurocytoma: A Novel Report from Nigeria in a 6-Year-Old Girl, and Review of Literature. ( 27746877 )
2016
8
Cerebellar liponeurocytoma: A case report and review of the literature. ( 26893691 )
2016
9
Cerebellar Liponeurocytoma: Relevant Clinical Cytogenetic Findings. ( 27750407 )
2016
10
Cerebellar liponeurocytoma in two siblings suggests a possible familial predisposition. ( 27349466 )
2016
11
Cerebellar Liponeurocytoma, an Unusual Tumor of the Central Nervous System - Ultrastructural Examination. ( 26107691 )
2015
12
Multifocal cerebellar liponeurocytoma. ( 26598433 )
2015
13
Cerebellar liponeurocytoma: a rare intracranial tumor with possible familial predisposition. Case report. ( 26613167 )
2015
14
Findings from positron emission tomography and genetic analyses for cerebellar liponeurocytoma. ( 25527206 )
2014
15
Cerebellar liponeurocytoma with extracranial extension: case report. ( 25482258 )
2014
16
The evolution of the anaplastic cerebellar liponeurocytoma: case report and review of the literature. ( 25250652 )
2014
17
Does "cerebellar liponeurocytoma" always reflect an expected site? An unusual case with a review of the literature. ( 24729347 )
2014
18
Cerebellar liponeurocytoma: case report. ( 23158671 )
2013
19
Photoclinic. Cerebellar liponeurocytoma. ( 23432178 )
2013
20
Multifocal cerebellar liponeurocytoma. ( 24257232 )
2013
21
Cerebellar liponeurocytoma with an unusually aggressive histopathology : case report and review of the literature. ( 23115671 )
2012
22
Magnetic resonance imaging of cerebellar liponeurocytoma. A case report and review of the literature. ( 24028986 )
2012
23
Cerebellar liponeurocytoma. ( 22849747 )
2012
24
Cerebellar liponeurocytoma: an updated follow-up of a case presenting histopathological and clinically aggressive features. ( 19439854 )
2009
25
Recurrent cerebellar liponeurocytoma with supratentorial extension. ( 19831141 )
2009
26
Cerebellar liponeurocytoma. ( 19680499 )
2009
27
Cerebellar liponeurocytoma with high proliferation index: treatment options. ( 19831140 )
2009
28
Adult cerebellar liponeurocytoma with predominant pilocytic pattern and myoid differentiation. ( 17239014 )
2007
29
Cerebellar liponeurocytoma. ( 15851097 )
2005
30
Cerebellar liponeurocytoma--a case report. ( 16758783 )
2005
31
Cerebellar liponeurocytoma: morphological, immunohistochemical, and ultrastructural study of a relapsed case. ( 15822821 )
2005
32
Cerebellar liponeurocytoma/lipidized medulloblastoma. ( 15719276 )
2005
33
Problematic differential diagnosis between cerebellar liponeurocytoma and anaplastic oligodendroglioma. ( 15327238 )
2004
34
Cerebellar liponeurocytoma (lipomatous medulloblastoma). ( 12717299 )
2003
35
Cerebellar liponeurocytoma: a case report and review of the literature. ( 15080526 )
2003
36
Cerebellar liponeurocytoma with an unusually aggressive clinical course: case report. ( 14633310 )
2003
37
Lipomatous medulloblastoma: a rare adult tumor variant with a uniquely favorable prognosis. ( 14670682 )
2003
38
Cerebellar liponeurocytoma: a newly recognized clinico-pathological entity. ( 12364938 )
2002
39
Cerebellar liponeurocytoma. Case report with considerations on prognosis and management. ( 12181694 )
2002
40
Neuroimaging of cerebellar liponeurocytoma. Case report. ( 11780904 )
2001
41
Cerebellar liponeurocytoma: immunohistochemical and ultrastructural study of a case. ( 11297321 )
2001
42
Cerebellar liponeurocytoma. Case report and review of the literature. ( 11596966 )
2001
43
Medulloblastoma with lipidized cells versus lipomatous medulloblastoma. ( 11128619 )
2000
44
Lipomatous medulloblastoma. ( 9266140 )
1997
45
Lipomatous medulloblastoma in adults: a new tumor type with possible favorable prognosis. ( 8026834 )
1994

Variations for Cerebellar Liponeurocytoma

Expression for Cerebellar Liponeurocytoma

Search GEO for disease gene expression data for Cerebellar Liponeurocytoma.

Pathways for Cerebellar Liponeurocytoma

Pathways related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.63 ENO2 GFAP MAP2 RBFOX3 SAG SYP
2
Show member pathways
11.61 PTCH1 SUFU TP53
3 11.34 GFAP NEUROG1 OLIG2
4 11.15 GFAP MAP2 OLIG2 SYP

GO Terms for Cerebellar Liponeurocytoma

Cellular components related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.46 ENO2 MAP2 NEUROG1 RBFOX3
2 perikaryon GO:0043204 9.13 ENO2 NEUROG1 RBFOX3
3 dendritic growth cone GO:0044294 8.62 MAP2 PTCH1

Biological processes related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron differentiation GO:0030182 9.33 ATOH1 NEUROG1 OLIG2
2 negative regulation of smoothened signaling pathway GO:0045879 9.26 PTCH1 SUFU
3 nervous system development GO:0007399 9.02 ATOH1 NEUROG1 OLIG2 RBFOX3 SMARCB1
4 spinal cord motor neuron differentiation GO:0021522 8.96 OLIG2 PTCH1

Sources for Cerebellar Liponeurocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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