MCID: CRB022
MIFTS: 36

Cerebellar Liponeurocytoma

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Cerebellar Liponeurocytoma

MalaCards integrated aliases for Cerebellar Liponeurocytoma:

Name: Cerebellar Liponeurocytoma 12 53 59 15 73
Lipomatous Medulloblastoma 12
Central Neurocytoma 73

Characteristics:

Orphanet epidemiological data:

59
cerebellar liponeurocytoma
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:6458
NCIt 50 C6905
SNOMED-CT 68 128858006
Orphanet 59 ORPHA251931
UMLS via Orphanet 74 C1370507
UMLS 73 C1370507

Summaries for Cerebellar Liponeurocytoma

MalaCards based summary : Cerebellar Liponeurocytoma, also known as lipomatous medulloblastoma, is related to oligodendroglioma and medulloblastoma, and has symptoms including headache and vomiting. An important gene associated with Cerebellar Liponeurocytoma is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Neural Crest Differentiation. Related phenotypes are Decreased viability in esophageal squamous lineage and Increased proliferation

Related Diseases for Cerebellar Liponeurocytoma

Diseases related to Cerebellar Liponeurocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 183)
# Related Disease Score Top Affiliating Genes
1 oligodendroglioma 28.6 ENO2 GFAP OLIG2 SYP TP53
2 medulloblastoma 26.6 ATOH1 ENO2 GFAP MAP2 PTCH1 SMARCB1
3 malignant sertoli cell tumor 10.9 ENO2 SYP
4 sinonasal undifferentiated carcinoma 10.9 ENO2 SYP
5 sensory organ benign neoplasm 10.9 ENO2 SYP
6 pancreatic somatostatinoma 10.9 ENO2 SYP
7 cutaneous ganglioneuroma 10.9 ENO2 SYP
8 extrahepatic bile duct adenocarcinoma 10.9 ENO2 SYP
9 orbital cancer 10.9 ENO2 SYP
10 middle ear adenoma 10.9 ENO2 SYP
11 ovarian carcinosarcoma 10.9 ENO2 SYP
12 desmoplastic infantile ganglioglioma 10.9 GFAP SYP
13 extraventricular neurocytoma 10.9 GFAP SYP
14 rosette-forming glioneuronal tumor 10.9 MAP2 SYP
15 lung combined type small cell carcinoma 10.8 GFAP SYP
16 sella turcica neoplasm 10.8 RBFOX3 SYP
17 intracranial cysts 10.8 ENO2 GFAP
18 tuberculum sellae meningioma 10.8 RBFOX3 SYP
19 malignant teratoma 10.8 ENO2 SYP
20 primitive neuroectodermal tumor of the cervix uteri 10.8 ENO2 GFAP
21 endometrial small cell carcinoma 10.8 ENO2 SYP
22 papillary tumor of the pineal region 10.8 ENO2 MAP2 SYP
23 cerebellar medulloblastoma 10.7 ENO2 GFAP
24 mucinous ovarian cystadenoma 10.7 ENO2 SYP
25 chiari malformation 10.7 GFAP MAP2 SYP
26 dysembryoplastic neuroepithelial tumor 10.7 GFAP MAP2 SYP
27 angiocentric glioma 10.7 GFAP SYP
28 gangliocytoma 10.7 GFAP RBFOX3 SYP
29 obstructive hydrocephalus 10.7 GFAP SYP
30 plexiform schwannoma 10.7 ENO2 GFAP
31 large cell carcinoma with rhabdoid phenotype 10.7 ENO2 SMARCB1
32 subependymal glioma 10.6 ENO2 GFAP SYP
33 benign ependymoma 10.6 ENO2 GFAP SYP
34 astroblastoma 10.6 ENO2 GFAP SYP
35 melanotic neuroectodermal tumor 10.6 ENO2 GFAP SYP
36 subependymal giant cell astrocytoma 10.6 ENO2 GFAP SYP
37 angiomyoma 10.6 ENO2 SYP
38 medulloepithelioma 10.6 GFAP SYP
39 pilomyxoid astrocytoma 10.6 GFAP SUFU SYP
40 ependymoma 10.6 ENO2 GFAP SYP
41 hemangioblastoma 10.6 ENO2 GFAP SYP
42 scrapie 10.6 ENO2 GFAP MAP2
43 kidney rhabdoid cancer 10.6 ENO2 SMARCB1
44 hemimegalencephaly 10.5 GFAP MAP2
45 retroperitoneal sarcoma 10.5 PLIN1 SMARCB1
46 esophageal neuroendocrine tumor 10.5 CHGA SYP
47 desmoplastic small round cell tumor 10.5 ENO2 SYP
48 ovarian large-cell neuroendocrine carcinoma 10.5 CHGA SYP
49 pineoblastoma 10.5 GFAP SAG SYP
50 adenoma of the pancreas 10.5 CHGA SYP

Graphical network of the top 20 diseases related to Cerebellar Liponeurocytoma:



Diseases related to Cerebellar Liponeurocytoma

Symptoms & Phenotypes for Cerebellar Liponeurocytoma

UMLS symptoms related to Cerebellar Liponeurocytoma:


headache, vomiting

GenomeRNAi Phenotypes related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.61 ATOH1 CHGA FABP4 GFAP MAP2 NEUROG1
2 Increased proliferation GR00094-A 8.62 SMARCB1 TP53

MGI Mouse Phenotypes related to Cerebellar Liponeurocytoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.17 NEUROG1 ATOH1 OLIG2 ENO2 PLIN1 PTCH1
2 growth/size/body region MP:0005378 10.11 CHGA OLIG2 ENO2 FABP4 PLIN1 PTCH1
3 cellular MP:0005384 10.06 NEUROG1 ATOH1 OLIG2 ENO2 FABP4 PTCH1
4 mortality/aging MP:0010768 10.06 NEUROG1 ATOH1 CHGA OLIG2 FABP4 PTCH1
5 nervous system MP:0003631 9.93 NEUROG1 ATOH1 OLIG2 ENO2 PTCH1 GFAP
6 muscle MP:0005369 9.8 OLIG2 FABP4 PLIN1 PTCH1 GFAP SMARCB1
7 no phenotypic analysis MP:0003012 9.5 NEUROG1 ATOH1 CHGA OLIG2 PTCH1 SUFU
8 vision/eye MP:0005391 9.17 OLIG2 PTCH1 GFAP SAG SMARCB1 SUFU

Drugs & Therapeutics for Cerebellar Liponeurocytoma

Search Clinical Trials , NIH Clinical Center for Cerebellar Liponeurocytoma

Genetic Tests for Cerebellar Liponeurocytoma

Anatomical Context for Cerebellar Liponeurocytoma

Publications for Cerebellar Liponeurocytoma

Articles related to Cerebellar Liponeurocytoma:

(show all 40)
# Title Authors Year
1
Supratentorial intracerebral cerebellar liponeurocytoma: A case report and literature review. ( 29480846 )
2018
2
Cerebellar liponeurocytoma - a rare entity: a case report. ( 29908563 )
2018
3
Cerebellar liponeurocytoma presenting as multifocal bilateral cerebellar hemispheric mass lesions. ( 28290424 )
2017
4
Cerebellar liponeurocytoma with atypical histological features - a rare example of a glioneuronal tumor. ( 28984116 )
2017
5
Cerebellar Liponeurocytoma: A Novel Report from Nigeria in a 6-Year-Old Girl, and Review of Literature. ( 27746877 )
2016
6
Cerebellar liponeurocytoma: A case report and review of the literature. ( 26893691 )
2016
7
Cerebellar Liponeurocytoma: Relevant Clinical Cytogenetic Findings. ( 27750407 )
2016
8
Cerebellar liponeurocytoma in two siblings suggests a possible familial predisposition. ( 27349466 )
2016
9
Cerebellar Liponeurocytoma, an Unusual Tumor of the Central Nervous System - Ultrastructural Examination. ( 26107691 )
2015
10
Multifocal cerebellar liponeurocytoma. ( 26598433 )
2015
11
Cerebellar liponeurocytoma: a rare intracranial tumor with possible familial predisposition. Case report. ( 26613167 )
2015
12
Findings from positron emission tomography and genetic analyses for cerebellar liponeurocytoma. ( 25527206 )
2014
13
Cerebellar liponeurocytoma with extracranial extension: case report. ( 25482258 )
2014
14
The evolution of the anaplastic cerebellar liponeurocytoma: case report and review of the literature. ( 25250652 )
2014
15
Cerebellar liponeurocytoma: case report. ( 23158671 )
2013
16
Photoclinic. Cerebellar liponeurocytoma. ( 23432178 )
2013
17
Multifocal cerebellar liponeurocytoma. ( 24257232 )
2013
18
Cerebellar liponeurocytoma with an unusually aggressive histopathology : case report and review of the literature. ( 23115671 )
2012
19
Magnetic resonance imaging of cerebellar liponeurocytoma. A case report and review of the literature. ( 24028986 )
2012
20
Cerebellar liponeurocytoma. ( 22849747 )
2012
21
FABP4 is a candidate marker of cerebellar liponeurocytomas. ( 22476608 )
2012
22
Cerebellar liponeurocytoma: an updated follow-up of a case presenting histopathological and clinically aggressive features. ( 19439854 )
2009
23
Recurrent cerebellar liponeurocytoma with supratentorial extension. ( 19831141 )
2009
24
Cerebellar liponeurocytoma. ( 19680499 )
2009
25
Cerebellar liponeurocytoma with high proliferation index: treatment options. ( 19831140 )
2009
26
Adult cerebellar liponeurocytoma with predominant pilocytic pattern and myoid differentiation. ( 17239014 )
2007
27
Cerebellar liponeurocytoma. ( 15851097 )
2005
28
Cerebellar liponeurocytoma--a case report. ( 16758783 )
2005
29
Cerebellar liponeurocytoma: morphological, immunohistochemical, and ultrastructural study of a relapsed case. ( 15822821 )
2005
30
Cerebellar liponeurocytoma/lipidized medulloblastoma. ( 15719276 )
2005
31
Genetic and expression profiles of cerebellar liponeurocytomas. ( 15446583 )
2004
32
Problematic differential diagnosis between cerebellar liponeurocytoma and anaplastic oligodendroglioma. ( 15327238 )
2004
33
Cerebellar liponeurocytoma (lipomatous medulloblastoma). ( 12717299 )
2003
34
Cerebellar liponeurocytoma: a case report and review of the literature. ( 15080526 )
2003
35
Cerebellar liponeurocytoma with an unusually aggressive clinical course: case report. ( 14633310 )
2003
36
Cerebellar liponeurocytoma: a newly recognized clinico-pathological entity. ( 12364938 )
2002
37
Cerebellar liponeurocytoma. Case report with considerations on prognosis and management. ( 12181694 )
2002
38
Neuroimaging of cerebellar liponeurocytoma. Case report. ( 11780904 )
2001
39
Cerebellar liponeurocytoma: immunohistochemical and ultrastructural study of a case. ( 11297321 )
2001
40
Cerebellar liponeurocytoma. Case report and review of the literature. ( 11596966 )
2001

Variations for Cerebellar Liponeurocytoma

Expression for Cerebellar Liponeurocytoma

Search GEO for disease gene expression data for Cerebellar Liponeurocytoma.

Pathways for Cerebellar Liponeurocytoma

Pathways related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.63 ENO2 GFAP MAP2 RBFOX3 SAG SYP
2 11.34 GFAP NEUROG1 OLIG2
3 11.15 GFAP MAP2 OLIG2 SYP

GO Terms for Cerebellar Liponeurocytoma

Cellular components related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.46 ENO2 MAP2 NEUROG1 RBFOX3
2 perikaryon GO:0043204 9.13 ENO2 NEUROG1 RBFOX3
3 dendritic growth cone GO:0044294 8.62 MAP2 PTCH1

Biological processes related to Cerebellar Liponeurocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron differentiation GO:0030182 9.33 ATOH1 NEUROG1 OLIG2
2 negative regulation of smoothened signaling pathway GO:0045879 9.26 PTCH1 SUFU
3 nervous system development GO:0007399 9.02 ATOH1 NEUROG1 OLIG2 RBFOX3 SMARCB1
4 spinal cord motor neuron differentiation GO:0021522 8.96 OLIG2 PTCH1

Sources for Cerebellar Liponeurocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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