MCID: CRB029
MIFTS: 29

Cerebellopontine Angle Tumor

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cerebellopontine Angle Tumor

MalaCards integrated aliases for Cerebellopontine Angle Tumor:

Name: Cerebellopontine Angle Tumor 12 15 71
Neoplasm of the Cerebellopontine Angle 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3200
NCIt 49 C5414
UMLS 71 C0474740

Summaries for Cerebellopontine Angle Tumor

Disease Ontology : 12 A brain stem cancer that is characterized by neoplasms in the fossa located in cerebellopotine angle.

MalaCards based summary : Cerebellopontine Angle Tumor, also known as neoplasm of the cerebellopontine angle, is related to facial paralysis and neurofibromatosis, type iv, of riccardi. An important gene associated with Cerebellopontine Angle Tumor is SDHD (Succinate Dehydrogenase Complex Subunit D). The drugs Methylprednisolone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include cerebellopotine angle, brain and bone, and related phenotypes are Increased homologous recombination repair frequency and Increased homologous recombination repair frequency

Related Diseases for Cerebellopontine Angle Tumor

Diseases related to Cerebellopontine Angle Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 facial paralysis 30.9 NF2 ANTXR2
2 neurofibromatosis, type iv, of riccardi 30.2 SDHD NF2
3 acoustic neuroma 12.0
4 neurilemmoma 10.6
5 meningioma, radiation-induced 10.6
6 meningioma, familial 10.6
7 spinal meningioma 10.6
8 secretory meningioma 10.6
9 lymphoplasmacyte-rich meningioma 10.6
10 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.6
11 neuroma 10.6
12 trigeminal neuralgia 10.5
13 epidermoid cysts 10.4
14 sensorineural hearing loss 10.4
15 hydrocephalus 10.4
16 pathologic nystagmus 10.3
17 hemifacial spasm, familial 10.3
18 branchiootic syndrome 1 10.3
19 hemifacial spasm 10.3
20 rare surgical neurologic disease 10.3
21 lipomatosis, multiple 10.2
22 pleomorphic lipoma 10.2
23 cerebrospinal fluid leak 10.2
24 cerebral falx meningioma 10.2 NF2 ANTXR2
25 medulloblastoma 10.1
26 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.1
27 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
28 cholesteatoma of middle ear 10.1
29 neurosarcoidosis 10.1
30 hemangioma 10.1
31 glioblastoma multiforme 10.1
32 astrocytoma 10.1
33 bacterial meningitis 10.1
34 aneurysm 10.1
35 anterior cranial fossa meningioma 10.1 NF2 ANTXR2
36 facial nerve disease 10.0 NF2 ANTXR2
37 colorectal cancer 10.0
38 keratitis, hereditary 10.0
39 meniere disease 10.0
40 sarcoidosis 1 10.0
41 arachnoid cysts, intracranial 10.0
42 nasopharyngeal carcinoma 10.0
43 hearing loss, noise-induced 10.0
44 paraganglioma 10.0
45 thrombosis 10.0
46 adenoid cystic carcinoma 10.0
47 meningoencephalitis 10.0
48 intracranial aneurysm 10.0
49 hemiplegia 10.0
50 otosclerosis 10.0

Graphical network of the top 20 diseases related to Cerebellopontine Angle Tumor:



Diseases related to Cerebellopontine Angle Tumor

Symptoms & Phenotypes for Cerebellopontine Angle Tumor

GenomeRNAi Phenotypes related to Cerebellopontine Angle Tumor according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased homologous recombination repair frequency GR00236-A-1 9.17 ANTXR2 KRT86 PCSK1N TMEM165
2 Increased homologous recombination repair frequency GR00236-A-2 9.17 KRT86 PCSK1N TMEM165

Drugs & Therapeutics for Cerebellopontine Angle Tumor

Drugs for Cerebellopontine Angle Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
2
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
3
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
4
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
5 Prednisolone acetate Approved, Vet_approved Phase 3 52-21-1
6
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
7 Anti-Inflammatory Agents Phase 3
8 Antiemetics Phase 3
9 Methylprednisolone Acetate Phase 3
10 Gastrointestinal Agents Phase 3
11 Autonomic Agents Phase 3
12 Hormone Antagonists Phase 3
13 Neuroprotective Agents Phase 3
14 Antineoplastic Agents, Hormonal Phase 3
15 Protective Agents Phase 3
16 glucocorticoids Phase 3
17 Hormones Phase 3
18
tannic acid Approved 1401-55-4
19
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
20
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
21
Rocuronium Approved 119302-91-9, 143558-00-3 441290

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Assessment of Corticosteroid Effect in the Prevention of Facial Palsy After Cerebella-pontine Angle Surgery Completed NCT00438087 Phase 3 methylprednisolone
2 Intraoperative Motor Evoked Potential Monitoring of Facial Nerve in Patients Undergoing Cerbellopontine Angle Tumer Resection Using Partial Versus no Neuromuscular Block Active, not recruiting NCT04148534
3 Evaluation of Endoscopic-assisted Microsurgical Removal of Cerebellopontine Angle Lesions Not yet recruiting NCT03228511

Search NIH Clinical Center for Cerebellopontine Angle Tumor

Genetic Tests for Cerebellopontine Angle Tumor

Anatomical Context for Cerebellopontine Angle Tumor

The Foundational Model of Anatomy Ontology organs/tissues related to Cerebellopontine Angle Tumor:

19
Cerebellopotine Angle

MalaCards organs/tissues related to Cerebellopontine Angle Tumor:

40
Brain, Bone, Salivary Gland, Testes, Eye, Cerebellum, Colon

Publications for Cerebellopontine Angle Tumor

Articles related to Cerebellopontine Angle Tumor:

(show top 50) (show all 189)
# Title Authors PMID Year
1
Diffusion Tensor Magnetic Resonance Imaging: An Example of its Usefulness in an Unusual Cerebellopontine Angle Tumor. 61
31834188 2020
2
Prognostic value of a bilateral motor threshold criterion for facial corticobulbar MEP monitoring during cerebellopontine angle tumor resection. 61
31784853 2019
3
Symptomatic Post-Radiosurgery Intratumoral Hemorrhage in a Case of Vestibular Schwannoma: A Case Report and Review of the Literature. 61
31770766 2019
4
Bilateral Internal Auditory Canal Metastasis of Colon Carcinoma Mimicking Neurofibromatosis Type II: A Case Report and Literature Review. 61
30862585 2019
5
Trigeminal neuralgia secondary to cerebellopontine angle tumor: A case report and brief overview. 61
31798267 2019
6
Functional results after facial reanimation in iatrogenic facial palsy. 61
31206851 2019
7
Securing Endotracheal Tube in a Bearded Patient Undergoing Surgery for Cerebellopontine Angle Tumor in Lateral Position-A Different Approach. 61
31022076 2019
8
Challenging Anterior Inferior Cerebellar Artery in Retrosigmoid Vestibular Schwannoma Removal. 61
30261396 2019
9
Evaluation of balance after surgery for cerebellopontine angle tumor. 61
30248037 2019
10
Choroid plexus papilloma presenting as an occipital mass with neck pain: Case report. 61
30235739 2018
11
Petrous Apex Pneumatization: Influence on Postoperative Cerebellopontine Angle Tumor Cerebrospinal Fluid Fistula. 61
29925246 2018
12
Primary Intracranial Rhabdomyosarcoma in the Cerebellopontine Angle Resected After Preoperative Embolization. 61
29777888 2018
13
Incidence and Risk Factors for Sigmoid Venous Thrombosis Following CPA Tumor Resection. 61
29738390 2018
14
Glioneuronal Heterotopia Presenting as Cerebellopontine Angle Tumor of Cranial Nerve VIII. 61
29625310 2018
15
Microvascular Decompression for Treatment of Trigeminal Neuralgia in Patient with Facial Nerve Schwannoma. 61
29477001 2018
16
The Management of Refractory Dry Eye With Semi-Scleral Contact Lens. 61
27203793 2018
17
The relation between flocculus volume and tinnitus after cerebellopontine angle tumor surgery. 61
29398141 2018
18
The Top 50 Most-Cited Articles on Acoustic Neuroma. 61
29288105 2018
19
Spontaneously Resolving Symptomatic Subdural Hygromas After Cerebellopontine Angle Tumor Surgery. 61
29101072 2018
20
Long-Term Hearing Preservation Outcomes for Small Vestibular Schwannomas: Retrosigmoid Removal Versus Observation. 61
29315192 2018
21
Focal hyperintensity in the dorsal brain stem of patients with cerebellopontine angle tumor: A high-resolution 3 T MRI study. 61
29343821 2018
22
The Management and Imaging of Vestibular Schwannomas. 61
28546250 2017
23
Trigeminal Ganglioneuroma: A Rare Case of Trigeminal Neuralgia Caused by Cerebellopontine Angle Tumor. 61
28043883 2017
24
Etiology of single-sided deafness and asymmetrical hearing loss. 61
28366032 2017
25
Facial nerve repair after operative injury: Impact of timing on hypoglossal-facial nerve graft outcomes. 61
27353412 2016
26
[Misdiagnosis of facial nerve schwannoma: a retrospective analysis and literature reviews]. 61
29871154 2016
27
Surgical treatment of vestibular schwannoma. Review of 420 cases. 61
26679233 2016
28
Multiple Unilateral Vestibular Schwannomas: Segmental NF2 or Sporadic Occurrence? 61
27354931 2016
29
Epidermoid cysts of the cerebellopontine angle: Clinical features and treatment outcomes. 61
26969562 2016
30
Bilaterally Abnormal Head Impulse Tests Indicate a Large Cerebellopontine Angle Tumor. 61
26754780 2016
31
Early Nerve Grafting for Facial Paralysis After Cerebellopontine Angle Tumor Resection With Preserved Facial Nerve Continuity. 61
26584060 2016
32
Clear Cell Carcinoma of Salivary Gland with Intracranial Extension Through Jugular Foramen. 61
26693463 2015
33
Pseudo-Cerebrospinal Fluid Rhinorrhea Resulting from Aberrant Cross-Innervation of Trigeminal and Facial Nerves following Skull Base Surgery. 61
26251813 2015
34
Fully endoscopic retrosigmoid approach for posterior petrous meningioma and trigeminal microvascular decompression. 61
25596641 2015
35
Effect of corticosteroids on facial function after cerebellopontine angle tumor removal: a double-blind study versus placebo. 61
25924803 2015
36
Auditory spatial deficits in brainstem disorders. 61
26652875 2015
37
Retrosigmoid removal of small acoustic neuroma: curative tumor removal with preservation of function. 61
24995779 2014
38
Exophytic cerebellar glioblastoma in the cerebellopontine angle: case report and review of the literature. 61
25083393 2014
39
[Airway rescue in a patient with severe obstructive sleep apnea syndrome and impossible ventilation after induction of general anesthesia]. 61
24979854 2014
40
Translabyrinthine resection of neurofibromatosis type 2 associated vestibular and facial schwannomas, repair of facial nerve, and placement of auditory brainstem implant. 61
24380525 2014
41
Comprehensive management of frontal and cerebellar tumor patients with personality changes and suicidal tendencies. 61
25593758 2014
42
Clinical use of skull tap vestibular evoked myogenic potentials for the diagnoses of the cerebellopontine angle tumor patients. 61
24804198 2014
43
Transient cardiac asystole induced by electrocautery during excision of a cerebellopontine angle tumor. 61
24262476 2013
44
A 68-year old man with a cerebellopontine angle tumor. 61
23936919 2013
45
Bruns nystagmus in cerebellopontine angle tumor. 61
23552728 2013
46
Malignant peripheral nerve sheath tumor at the cerebellopontine angle treated with Gamma Knife radiosurgery: case report and review of the literature. 61
29296354 2013
47
Retrosigmoid approach to cerebellopontine angle tumor resection: surgical modifications. 61
22815095 2012
48
Intraoperative Transcranial Motor-Evoked Potential Monitoring of the Facial Nerve during Cerebellopontine Angle Tumor Resection. 61
24083121 2012
49
Tongue swelling and necrosis after brain tumor surgery. 61
23559991 2012
50
Bruns-Cushing nystagmus due to hypertensive unilateral paramedian pontine base infarction. 61
21855254 2012

Variations for Cerebellopontine Angle Tumor

Expression for Cerebellopontine Angle Tumor

Search GEO for disease gene expression data for Cerebellopontine Angle Tumor.

Pathways for Cerebellopontine Angle Tumor

GO Terms for Cerebellopontine Angle Tumor

Sources for Cerebellopontine Angle Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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