MCID: CRB029
MIFTS: 29

Cerebellopontine Angle Tumor

Categories: Cancer diseases, Neuronal diseases
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Aliases & Classifications for Cerebellopontine Angle Tumor

MalaCards integrated aliases for Cerebellopontine Angle Tumor:

Name: Cerebellopontine Angle Tumor 11 14 71
Neoplasm of the Cerebellopontine Angle 11
Cerebellopontine Angle Tumour 11

Classifications:



External Ids:

Disease Ontology 11 DOID:3200
NCIt 49 C5414
UMLS 71 C0474740

Summaries for Cerebellopontine Angle Tumor

Disease Ontology: 11 A brain stem cancer that is characterized by neoplasms in the fossa located in cerebellopotine angle.

MalaCards based summary: Cerebellopontine Angle Tumor, also known as neoplasm of the cerebellopontine angle, is related to acoustic neuroma and neurilemmoma. An important gene associated with Cerebellopontine Angle Tumor is NF2 (NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor). The drugs Benzocaine and Tannic acid have been mentioned in the context of this disorder. Affiliated tissues include cerebellopotine angle, brain and salivary gland, and related phenotypes are Increased proliferation and digestive/alimentary

Related Diseases for Cerebellopontine Angle Tumor

Diseases related to Cerebellopontine Angle Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 acoustic neuroma 32.3 SMARCB1 NF2 FKBP4
2 neurilemmoma 31.1 SMARCB1 NF2
3 bell's palsy 30.8 KANTR FKBP4
4 facial paralysis 30.6 NF2 KANTR FKBP4
5 neurofibromatosis, type ii 30.1 SMARCB1 NF2
6 meningioma, familial 10.4
7 neuroma 10.4
8 trigeminal neuralgia 10.4
9 central nervous system origin vertigo 10.3
10 epidermoid cysts 10.3
11 vascular disease 10.3
12 cerebrospinal fluid leak 10.3
13 foramen magnum meningioma 10.2 NF2 KANTR
14 glossopharyngeal nerve disease 10.2 NF2 KANTR
15 posterior pituitary gland neoplasm 10.2 SMARCB1 NF2
16 peripheral nerve schwannoma 10.2 SMARCB1 NF2
17 pineal region meningioma 10.2 SMARCB1 NF2
18 optic nerve sheath meningioma 10.2 SMARCB1 NF2
19 plexiform schwannoma 10.2 SMARCB1 NF2
20 schwannomatosis 1 10.2 SMARCB1 NF2
21 olfactory groove meningioma 10.2 SMARCB1 NF2
22 sphenoorbital meningioma 10.2 RGPD3 NF2
23 anterior cranial fossa meningioma 10.2 SMARCB1 NF2
24 cavernous sinus meningioma 10.2 RGPD3 NF2
25 cellular schwannoma 10.2 SMARCB1 NF2
26 chordoid meningioma 10.2 SMARCB1 NF2
27 intraventricular meningioma 10.2 RGPD3 NF2
28 brain meningioma 10.2 SMARCB1 NF2
29 transitional meningioma 10.2 SMARCB1 NF2
30 atypical neurofibroma 10.2 SMARCB1 NF2
31 secretory meningioma 10.2 SMARCB1 NF2
32 optic nerve neoplasm 10.2 SMARCB1 NF2
33 melanotic neurilemmoma 10.2 SMARCB1 NF2
34 petroclival meningioma 10.2 RGPD3 NF2
35 papillon-lefevre syndrome 10.2
36 skull base meningioma 10.2 SMARCB1 NF2
37 petrous apex meningioma 10.2 NF2 KANTR
38 spinal canal and spinal cord meningioma 10.2 SMARCB1 NF2
39 spinal meningioma 10.2 SMARCB1 NF2
40 meningothelial meningioma 10.2 SMARCB1 NF2
41 spinal cord ependymoma 10.2 SMARCB1 NF2
42 skull base cancer 10.2 SMARCB1 NF2
43 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.2
44 neurofibromatosis 10.2
45 pathologic nystagmus 10.2
46 sudden sensorineural hearing loss 10.2
47 fibrous meningioma 10.2 SMARCB1 NF2
48 cranial nerve palsy 10.2 NF2 KANTR
49 cranial nerve malignant neoplasm 10.1 SMARCB1 NF2
50 intracranial meningioma 10.1 SMARCB1 NF2

Graphical network of the top 20 diseases related to Cerebellopontine Angle Tumor:



Diseases related to Cerebellopontine Angle Tumor

Symptoms & Phenotypes for Cerebellopontine Angle Tumor

GenomeRNAi Phenotypes related to Cerebellopontine Angle Tumor according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Cerebellopontine Angle Tumor:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 CTSS FKBP4 NF2 SLC26A2 SMARCB1

Drugs & Therapeutics for Cerebellopontine Angle Tumor

Drugs for Cerebellopontine Angle Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
2
Tannic acid Approved 1401-55-4 16129878 16129778
3 Neuromuscular Nondepolarizing Agents
4 Neuromuscular Blocking Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base Unknown status NCT04249921
2 Evaluation of Endoscopic-assisted Microsurgical Removal of Cerebellopontine Angle Lesions Unknown status NCT03228511
3 Intraoperative Monitoring of Facial Nerve in Patients Undergoing Cerbellopontine Angle Tumer Resection Using Partial Versus no Neuromuscular Block Completed NCT04148534 Rocroniom, Non Depolarizing Muscle Relaxant

Search NIH Clinical Center for Cerebellopontine Angle Tumor

Genetic Tests for Cerebellopontine Angle Tumor

Anatomical Context for Cerebellopontine Angle Tumor

Organs/tissues related to Cerebellopontine Angle Tumor:

FMA: Cerebellopotine Angle
MalaCards : Brain, Salivary Gland, Trigeminal Ganglion, Cerebellum, Spinal Cord, Bone, Tongue

Publications for Cerebellopontine Angle Tumor

Articles related to Cerebellopontine Angle Tumor:

(show top 50) (show all 268)
# Title Authors PMID Year
1
Objective measurement of HINTS (Head Impulse, Nystagmus, Test of Skew) in peripheral vestibulopathy. 62
35339313 2022
2
Exophytic cerebellopontine angle tumor showing mostly an embryonal appearance with H3-3A K27M. 62
36221932 2022
3
Anticipating facial nerve position using 3D tractography during the preoperative assessment of cerebellopontine angle tumors. 62
36195179 2022
4
Cochlear Obliteration after Translabyrinthine Resection for Large Cerebellopontine Angle Tumor. 62
36075191 2022
5
Clinical characteristics of patients with dizziness/vertigo showing a dissociation between caloric and video head impulse test results. 62
35817592 2022
6
Effect of Household Income on Short-Term Outcomes Following Cerebellopontine Angle Tumor Resection. 62
35832987 2022
7
Predicting surgical decision-making in vestibular schwannoma using tree-based machine learning. 62
35364585 2022
8
The role of socioeconomic status on outcomes following cerebellopontine angle tumor resection. 62
33423556 2022
9
Unilateral glossodynia as a harbinger of an occult cerebellopontine angle tumour. 62
35414584 2022
10
Intermediate-grade primary melanocytic neoplasm of the cerebellopontine angle: A diagnostic challenge. 62
35243908 2022
11
Comparison of the Functional State and Motor Skills of Patients after Cerebral Hemisphere, Ventricular System, and Cerebellopontine Angle Tumor Surgery. 62
35206503 2022
12
When paediatric facial nerve paralysis is not a Bell's palsy: A case of cerebellopontine angle tumour. 62
35140576 2022
13
Primary pilocytic astrocytoma of the cerebellopontine angle in pediatric patient with neurofibromatosis type 1: a case report. 62
36061231 2022
14
Direction-changing spontaneous nystagmus in cerebellopontine angle tumour. 62
34929634 2022
15
3D Printing-Assisted Skull Base Tumor Surgeries: An Institutional Experience. 62
34737495 2021
16
Bone Cement Internal Auditory Canal Reconstruction to Reduce CSF Leak After Vestibular Schwannoma Retrosigmoid Approach. 62
34121078 2021
17
The utility of augmented reality in lateral skull base surgery: A preliminary report. 62
33556837 2021
18
Sudden and Asymmetric Hearing Loss Among Active Duty Service Members: Underscoring the Importance of Active Screening. 62
33608725 2021
19
Intraoperative transcranial facial motor evoked potential monitoring in surgery of cerebellopontine angle tumors predicts early and late postoperative facial nerve function. 62
33636603 2021
20
Gender is associated with long-term mortality after cerebellopontine angle tumor resection. 62
33422925 2021
21
Far Lateral Approach for Malignant, Severely Calcified Cerebellopontine Angle Tumor. 62
33717809 2021
22
Association of Neurosurgical Work Relative Value Units with Objective Markers of Operative Complexity. 62
33091644 2021
23
Impact of extent of internal acoustic meatus tumor removal using translabyrinthine approach for acoustic neuroma surgery. 62
34351928 2021
24
Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery-A Systematic Review and Future Perspectives. 62
34239858 2021
25
Deadly complication of sacrificing superior petrosal vein during cerebellopontine angle tumor resection: A case report and literature review. 62
34345447 2021
26
Prognostic value of a bilateral motor threshold criterion for facial corticobulbar MEP monitoring during cerebellopontine angle tumor resection. 62
31784853 2020
27
Spontaneous Regression of Radiologically Diagnosed Epidermoid Cyst Originating from the Cerebellopontine Angle. 62
32971281 2020
28
[Hearing without ears]. 62
33332038 2020
29
Effect of lifestyle and dietary factors in the development of brain tumors. 62
33409188 2020
30
Masseter-to-Facial Cranial Nerve Anastomosis: A Report of 30 Cases. 62
32542367 2020
31
[Diffuse Leptomeningeal Glioneuronal Tumor with Subarachnoid Hemorrhage:A Case Report]. 62
32938808 2020
32
Securing Endotracheal Tube in a Bearded Patient Undergoing Surgery for Cerebellopontine Angle Tumor in Lateral Position-A Different Approach. 62
31022076 2020
33
Potential Confounding Factors May Influence the Association Between Configurations of the Vertebrobasilar System and the Incidence of Idiopathic Sudden Sensorineural Hearing Loss and Canal Paresis. 62
32150021 2020
34
Nadroparin Plus Compression Stockings versus Nadroparin Alone for Prevention of Venous Thromboembolism in Cerebellopontine Angle Tumour Excisions: A Cohort Study. 62
32028534 2020
35
Short lasting unilateral neuralgiform headache with conjunctival injection and tearing as a presenting manifestation of contralateral cerebellopontine angle tumor. 62
32415038 2020
36
Functional results after facial reanimation in iatrogenic facial palsy. 62
31206851 2020
37
Atypical teratoid rhabdoid tumor (AT/RT) at the cerebellopontine angle arising from acoustic nerve with facial nerve palsy: report of a case. 62
33042346 2020
38
Diffusion Tensor Magnetic Resonance Imaging: An Example of its Usefulness in an Unusual Cerebellopontine Angle Tumor. 62
31834188 2020
39
Hypoglossal Facial Nerve Anastomosis for Post-Operative and Post-Traumatic Complete Facial Nerve Paralysis. 62
32165940 2019
40
Bilateral Internal Auditory Canal Metastasis of Colon Carcinoma Mimicking Neurofibromatosis Type II: A Case Report and Literature Review. 62
30862585 2019
41
Trigeminal neuralgia secondary to cerebellopontine angle tumor: A case report and brief overview. 62
31798267 2019
42
Symptomatic Post-Radiosurgery Intratumoral Hemorrhage in a Case of Vestibular Schwannoma: A Case Report and Review of the Literature. 62
31770766 2019
43
Challenging Anterior Inferior Cerebellar Artery in Retrosigmoid Vestibular Schwannoma Removal. 62
30261396 2019
44
Evaluation of balance after surgery for cerebellopontine angle tumor. 62
30248037 2019
45
Primary central nervous system lymphoma mimicking cerebellopontine angle tumour. 62
27452624 2018
46
Choroid plexus papilloma presenting as an occipital mass with neck pain: Case report. 62
30235739 2018
47
Petrous Apex Pneumatization: Influence on Postoperative Cerebellopontine Angle Tumor Cerebrospinal Fluid Fistula. 62
29925246 2018
48
Hemifacial spasm secondary to vascular loop compression: a rare case report. 62
30484026 2018
49
Primary Intracranial Rhabdomyosarcoma in the Cerebellopontine Angle Resected After Preoperative Embolization. 62
29777888 2018
50
Glioneuronal Heterotopia Presenting as Cerebellopontine Angle Tumor of Cranial Nerve VIII. 62
29625310 2018

Variations for Cerebellopontine Angle Tumor

Expression for Cerebellopontine Angle Tumor

Search GEO for disease gene expression data for Cerebellopontine Angle Tumor.

Pathways for Cerebellopontine Angle Tumor

GO Terms for Cerebellopontine Angle Tumor

Sources for Cerebellopontine Angle Tumor

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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