MCID: CRB030
MIFTS: 32

Cerebellum Cancer

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cerebellum Cancer

MalaCards integrated aliases for Cerebellum Cancer:

Name: Cerebellum Cancer 12 15 17
Cerebellar Neoplasms 45 74
Malignant Neoplasm of Cerebellum 74
Malignant Tumor of Cerebellum 12
Cerebellar Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4205
ICD9CM 36 191.6
MeSH 45 D002528
NCIt 51 C2935 C3569
ICD10 34 C71.6

Summaries for Cerebellum Cancer

MalaCards based summary : Cerebellum Cancer, also known as cerebellar neoplasms, is related to cerebellar medulloblastoma and medulloblastoma, and has symptoms including cerebellar ataxia An important gene associated with Cerebellum Cancer is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include cerebellum, brain and cortex, and related phenotypes are behavior/neurological and nervous system

Related Diseases for Cerebellum Cancer

Diseases related to Cerebellum Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 cerebellar medulloblastoma 31.7 ENO2 MBNL3
2 medulloblastoma 28.3 ATOH1 ENO2 MAP2 SHH SYP
3 adult cerebellar neoplasm 12.1
4 childhood cerebellar neoplasm 12.1
5 acinar cell cystadenocarcinoma 10.3 SERPINA3 SYP
6 epithelioid leiomyosarcoma 10.2 ENO2 SERPINA3
7 carotid body cancer 10.2 ENO2 SYP
8 malignant sertoli cell tumor 10.2 ENO2 SYP
9 urinary bladder small cell neuroendocrine carcinoma 10.2 ENO2 SYP
10 auditory system cancer 10.2 ENO2 SYP
11 sinonasal undifferentiated carcinoma 10.2 ENO2 SYP
12 pancreatic somatostatinoma 10.2 ENO2 SYP
13 cutaneous ganglioneuroma 10.2 ENO2 SYP
14 ganglioneuroma 10.2 ENO2 SYP
15 extrahepatic bile duct adenocarcinoma 10.2 ENO2 SYP
16 small cell carcinoma 10.2 ENO2 SYP
17 small cell carcinoma of the bladder 10.2 ENO2 SYP
18 sensory organ benign neoplasm 10.2 ENO2 SYP
19 orbital cancer 10.2 ENO2 SYP
20 middle ear adenoma 10.2 ENO2 SYP
21 pulmonary large cell neuroendocrine carcinoma 10.2 ENO2 SYP
22 large cell neuroendocrine carcinoma 10.2 ENO2 SYP
23 gallbladder small cell carcinoma 10.2 ENO2 SYP
24 atypical follicular adenoma 10.2 ENO2 SYP
25 central nervous system primitive neuroectodermal neoplasm 10.2 ENO2 SYP
26 clear cell ependymoma 10.2 ENO2 SYP
27 ependymoma 10.2 ENO2 SYP
28 cerebral neuroblastoma 10.2 ENO2 SYP
29 cauda equina neoplasm 10.2 ENO2 SYP
30 endometrial small cell carcinoma 10.2 ENO2 SYP
31 extraosseous chondrosarcoma 10.2 ENO2 SYP
32 subependymal glioma 10.2 ENO2 SYP
33 malignant teratoma 10.2 ENO2 SYP
34 teratoma 10.2 ENO2 SYP
35 astroblastoma 10.2 ENO2 SYP
36 cerebral ventricle cancer 10.2 ENO2 SYP
37 olfactory nerve neoplasm 10.2 ENO2 SYP
38 pineal gland cancer 10.2 ENO2 SYP
39 autonomic nervous system benign neoplasm 10.2 ENO2 SYP
40 melanotic neuroectodermal tumor 10.2 ENO2 SYP
41 benign ependymoma 10.2 ENO2 SYP
42 nodular ganglioneuroblastoma 10.2 ENO2 SYP
43 ganglioneuroblastoma 10.2 ENO2 SYP
44 pineocytoma 10.2 ENO2 SYP
45 rhabdoid cancer 10.2 ENO2 SYP
46 angiomyoma 10.2 ENO2 SYP
47 cervical clear cell adenocarcinoma 10.2 ENO2 SYP
48 gastric small cell carcinoma 10.2 ENO2 SYP
49 desmoplastic small round cell tumor 10.2 ENO2 SYP
50 subependymoma 10.2 ENO2 SYP

Comorbidity relations with Cerebellum Cancer via Phenotypic Disease Network (PDN):


Obstructive Hydrocephalus

Graphical network of the top 20 diseases related to Cerebellum Cancer:



Diseases related to Cerebellum Cancer

Symptoms & Phenotypes for Cerebellum Cancer

UMLS symptoms related to Cerebellum Cancer:


cerebellar ataxia

MGI Mouse Phenotypes related to Cerebellum Cancer:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.43 ATOH1 ENO2 MAP2 MBNL3 SHH SYP
2 nervous system MP:0003631 9.1 ATOH1 ENO2 MAP2 PNKP SHH SYP

Drugs & Therapeutics for Cerebellum Cancer

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cerebellum - Cognitive Outcome and Functional Connectivity Unknown status NCT01730274
2 Impact of Cerebellar Mass Resection on Pain Processing Completed NCT02261649
3 Advanced MRI for Posterior Fossa Tumours Recruiting NCT03471026

Search NIH Clinical Center for Cerebellum Cancer

Cochrane evidence based reviews: cerebellar neoplasms

Genetic Tests for Cerebellum Cancer

Anatomical Context for Cerebellum Cancer

MalaCards organs/tissues related to Cerebellum Cancer:

42
Cerebellum, Brain, Cortex

Publications for Cerebellum Cancer

Articles related to Cerebellum Cancer:

# Title Authors Year
1
Use of T2 signal intensity of cerebellar neoplasms in pediatric patients to guide preoperative staging of the neuraxis. ( 21284463 )
2011
2
Findings on preoperative brain MRI predict histopathology in children with cerebellar neoplasms. ( 21921669 )
2011
3
Cerebellar neoplasms in children. ( 2385809 )
1990
4
The transitory superficial granular layer of the cerebellar cortex; its relationship to certain cerebellar neoplasms. ( 15436307 )
1950

Variations for Cerebellum Cancer

Expression for Cerebellum Cancer

Search GEO for disease gene expression data for Cerebellum Cancer.

Pathways for Cerebellum Cancer

Pathways related to Cerebellum Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 ENO2 MAP2 SYP
2 10.7 MAP2 SHH SYP

GO Terms for Cerebellum Cancer

Biological processes related to Cerebellum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inner ear development GO:0048839 9.16 ATOH1 SHH
2 cellular response to organic substance GO:0071310 8.96 MAP2 SYP
3 establishment of cell polarity GO:0030010 8.62 MAP2 SHH

Sources for Cerebellum Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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