Cerebral Aneurysms

Categories: Cardiovascular diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 53
Cerebral Aneurysm 54 70
Cerebral Arterial Aneurysm 70


External Ids:

UMLS 70 C0917996 C1290398

Summaries for Cerebral Aneurysms

NINDS : 53 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and varicose veins. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Degradation of the extracellular matrix and Interleukin-4 and 13 signaling. The drugs Cilostazol and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and kidney, and related phenotype is neoplasm.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 395)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 31.8 MMP2 ELN
2 varicose veins 29.8 MMP2 ELN
3 homocysteinemia 29.6 ELN CST3
4 vascular disease 29.5 HMOX1 ELN CST3
5 arteriosclerosis 29.5 HMOX1 ELN CST3
6 aortic aneurysm, familial abdominal, 1 29.4 MMP2 ELN ELANE CST3
7 peripheral artery disease 29.3 HMOX1 CST3
8 pseudoxanthoma elasticum 29.2 MMP2 ELN
9 acute pancreatitis 29.2 ELANE CTSB
10 myocardial infarction 28.7 MMP2 HMOX1 ELN CST3
11 dilated cardiomyopathy 28.6 MMP2 HMOX1 ELN CTSB
12 heart disease 28.5 MMP2 HMOX1 ELN ELANE CST3
13 aneurysm 11.3
14 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.2
15 loeys-dietz syndrome 4 11.1
16 aneurysm, intracranial berry, 12 11.0
17 hydrocephalus 10.5
18 arteriovenous malformation 10.5
19 polycystic kidney disease 10.3
20 renal hypertension 10.3
21 ocular motor apraxia 10.3
22 cerebrovascular disease 10.3
23 arteriovenous malformations of the brain 10.2
24 endocarditis 10.2
25 headache 10.2
26 pica disease 10.2
27 autosomal dominant polycystic kidney disease 10.2
28 coarctation of aorta 10.2
29 infective endocarditis 10.2
30 kidney disease 10.2
31 neurofibromatosis 10.2
32 meningioma, familial 10.1
33 intracranial meningioma 10.1
34 secretory meningioma 10.1
35 lymphoplasmacyte-rich meningioma 10.1
36 exophthalmos 10.1
37 thunderclap headache 10.1
38 intracranial berry aneurysm 10.1
39 thrombosis 10.1
40 hemiplegia 10.1
41 transient cerebral ischemia 10.1
42 aortic aneurysm 10.1
43 carotid artery occlusion 10.1
44 seizure disorder 10.1
45 senile ectropion 10.1 MMP2 ELN
46 familial cerebral saccular aneurysm 10.1
47 renovascular hypertension 10.1
48 acute kidney failure 10.1
49 supravalvular aortic stenosis 10.1 MMP2 ELN
50 pelvic organ prolapse 10.1 MMP2 ELN

Graphical network of the top 20 diseases related to Cerebral Aneurysms:

Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

MGI Mouse Phenotypes related to Cerebral Aneurysms:

# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CST3 CTSB ELANE MMP2

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
tannic acid Approved Phase 4 1401-55-4
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
5 Hypnotics and Sedatives Phase 4
6 Respiratory System Agents Phase 4
7 Anti-Asthmatic Agents Phase 4
8 Purinergic P2Y Receptor Antagonists Phase 4
9 Vasodilator Agents Phase 4
10 Phosphodiesterase 3 Inhibitors Phase 4
11 Prasugrel hydrochloride Phase 4 389574-19-0
12 Neuroprotective Agents Phase 4
13 Phosphodiesterase Inhibitors Phase 4
14 Protective Agents Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16 Antipyretics Phase 4
17 Bronchodilator Agents Phase 4
18 Anesthetics, General Phase 4
19 Anesthetics, Inhalation Phase 4
20 Anesthetics, Intravenous Phase 4
Ticagrelor Approved Phase 3 274693-27-5 9871419
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
23 Analgesics, Non-Narcotic Phase 3
24 Analgesics Phase 3
25 Antirheumatic Agents Phase 3
26 Anti-Inflammatory Agents Phase 3
27 Anti-Inflammatory Agents, Non-Steroidal Phase 3
28 Cyclooxygenase Inhibitors Phase 3
29 Salicylates Phase 3
Nimodipine Approved, Investigational Phase 1, Phase 2 66085-59-4 4497
Heparin Approved, Investigational Phase 2 9005-49-6 772 9812414
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030
35 Calcium, Dietary Phase 1, Phase 2
36 calcium channel blockers Phase 1, Phase 2
37 Antihypertensive Agents Phase 1, Phase 2
38 Anticoagulants Phase 2
39 calcium heparin Phase 2
40 Antibiotics, Antitubercular Phase 2
41 Anti-Bacterial Agents Phase 2
42 Immunosuppressive Agents Phase 2
43 Antifungal Agents Phase 2
44 Anti-Infective Agents Phase 2
45 Immunologic Factors Phase 2
46 Tin Fluorides Phase 2
Calcium Nutraceutical Phase 1, Phase 2 7440-70-2 271
Bupivacaine Approved, Investigational Phase 1 38396-39-3, 2180-92-9 2474
Vitamin A Approved, Nutraceutical, Vet_approved Phase 1 68-26-8, 11103-57-4 445354
50 Retinol palmitate Phase 1

Interventional clinical trials:

(show top 50) (show all 67)
# Name Status NCT ID Phase Drugs
1 Comparison of Dual-Antiplatelet and Triple-Antiplatelet Preparation Using P2Y12 Assay in Patients With High On-Treatment Platelet Reactivity Undergoing Stent-Assisted Coil Embolization for An Unruptured Intracranial Aneurysm Completed NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
2 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function in Patients Undergoing Intracranial Aneurysm Surgery. Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
3 Effect of Preoperative Intravenous Ferric Carboxymaltose on Postoperative Transfusion Reduction in Anemia Patients Scheduled for Clipping Surgery for Unruptured Intracranial Aneurysms Not yet recruiting NCT04616092 Phase 4 FEFINJECT
4 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
5 Ticagrelor Versus Clopidogrel for Platelet Inhibition in Patients Undergoing Neurovascular Stenting for Intracranial Aneurysm Completed NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
6 Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain Aneurysms(EVOLVE): A Phase 3 Multicenter Randomized Study Recruiting NCT04192955 Phase 3 Acetyl Salicylate
7 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
8 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
9 Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms Not yet recruiting NCT04141020 Phase 2 Sirolimus
10 Evaluation of Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage From a Cerebral Aneurysm Terminated NCT02176837 Phase 2 Sodium Nitrite
11 Short Term Application of Sevoflurane in Patients With Subarachnoid Haemorrhage: a Feasibility and Safety Study Withdrawn NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
12 Estrogen Therapy as Prevention in the Progression of Aneurysm Withdrawn NCT01895881 Phase 2 Estradiol;Placebo
13 Prophylactic Remote Ischemic Preconditioning for Cerebral Vasospasm Following Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
14 Aspirin as a Promising Agent to Attenuate Inflammation in the Wall of Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
15 Efficacy Of Ultrasound Guided Stellate Ganglion Block To Relieve Vasospasm Following Clipping Of Cerebral Aneurysm Completed NCT02775318 Phase 1 Bupivacaine
16 Epidemiology of Cerebral Aneurysms With MRA in China in Middle-aged or Elder Person: a Population-based Survey Unknown status NCT00926172
17 The Role of Remote Ischemic Preconditioning in the Prevention of Ischemic Brain Damage During Intracranial Aneurysm Treatment (RIPAT) - A Prospective Randomized Exploratory Study Unknown status NCT02162654
18 TARGET Intracranial Aneurysm Coiling Registry: A Prospective Clinical Efficacy and Safety Study of Stryker Target® 360°, Target® Helical, and 2nd Generation Target® Nano Coils Unknown status NCT01748903
19 Effect of Dexmedetomidine on Maintenance and Recovery of Cranial Aneurysm Surgery Unknown status NCT03355534 Intravenous dexmedetomidine;nasal dexmedetomidine;intravenous saline;nasal saline
20 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520
21 Identification of Genetic Polymorphisms Related to Propofol Requirement and Recovery Through Genome-wide Association Study (GWAS) in Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Unknown status NCT03087383
22 Effects of Valproic Acid and Magnesium Sulphate on Rocuronium Requirement and Postoperative Analgesia in Patients Undergoing Craniotomy for Cerebrovascular Surgery Unknown status NCT01460563 Magnesium Sulfate;0.9% saline;0.9% saline
23 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395
24 New Therapeutic System of Unruptured Intracranial Aneurysms Based on Big Data From Chinese Population Unknown status NCT03153865
25 Searching a Dysfunction of Corticotropic and Thyrotropin Axis During the Acute Phase ( ≤48h ) of a Subarachnoid Hemorrhage Secondary to Spontaneous Rupture of Cerebral Aneurysm: Impact on the Incidence of Complications and Recovery at 1 Month Unknown status NCT03655509
26 Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Completed NCT02700126
27 New Generation Hydrogel Endovascular Aneurysm Treatment Trial Completed NCT01407952
28 DELTA Trial: Does Embolization With Larger Coils Lead to Better Treatment of Aneurysms Trial Completed NCT01943591
29 Computed Tomographic Perfusion and Computed Tomographic Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage Completed NCT00962546
30 Safety of Rapid Ventricular Pacing During Cerebral Aneurysm Surgery by Multimodal Neuromonitoring Completed NCT03185091
31 Impact of Intravascular Fluid Resuscitation on Whole Blood Viscosity During Coiling Embolization Procedure for Cerebral Artery Aneurysm Completed NCT02700607 Intravenous Crystalloid;Intravenous HES
32 Pipeline Flex With SHield Technology Embolization - An International MulticEnter ObservationaL Post Market StuDy of Treated Intra Cranial Aneurysms (SHIELD) Completed NCT02719522
33 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395
34 Gaining Efficacy Long Term: Hydrosoft, an Emerging, New, Embolic Coil (Gel-the-nec) Completed NCT01000675
35 Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients - A Prospective, Blinded Randomized Controlled Trial Completed NCT02507999
36 Cerebral Oxygenation and Metabolism in Patients Undergoing Clipping of Cerebral Aneurysm: A Comparative Study Between Propofol-based Total Intravenous Anesthesia and Sevoflurane-based Inhalational Anesthesia Completed NCT03778723 Total intravenous anesthesia (TIVA);Inhalation Anesthesia;Rescue fentanyl
37 Evaluation of Effort and Time Efficiency of Surgical Theater's Surgery Rehearsal Platform (SRP) for Cerebral Aneurysm Clipping Surgery Completed NCT02099318
38 The Use of the Classic Laryngeal Mask Airway in Patients With Cerebral Aneurysm Undergoing Endovascular Therapy Completed NCT03288519
39 Effect of Acupuncture on Inflammation and Immune Function After Craniotomy Completed NCT02761096
40 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
41 Barrow Ruptured Aneurysm Study Completed NCT01593267
42 A Comparison of the EEGo and BIS Monitors to Assess Emergence From Neuroanesthesia Completed NCT00443807
43 Cerebral Aneurysms: a Retrospective Study on the Experience in Our Hospital With a Comparative Analysis Between the Different Techniques Used in Its Treatment Completed NCT04792944 Urokinase
44 A Feasibility Study to Evaluate the Safety and Effectiveness of Implantation of 'Flowise Cerebral Flow Diverter' for the Treatment of Unruptured Wide-necked Cerebral Aneurysm in the Internal Carotid Artery Completed NCT02609867
45 Predicting Cerebral Aneurysm Recurrence Using Doppler Guidewire Measurements Completed NCT03145701
46 A Case-control Study of Independent Predictors of Middle Cerebral Artery Aneurysm. Completed NCT03493035
47 Framing Eighteen Coils in Cerebral Aneurysms Trial: FEAT Recruiting NCT01655784
48 The RISE Trial: A Randomized Trial on Intra-Saccular Endobridge Devices Recruiting NCT03936647
49 The Safety and Clinical Effectiveness of Pipeline™ Flex Embolization Devices With Shield Technology™ in Patients With Intracranial Aneurysms: a Multicentre Retrospective Study of an Australian Cohort (SCOPE-AUS) Recruiting NCT03815149
50 An Evaluation of Effectiveness and Safety of the CorPath® GRX System in Endovascular Embolization Procedures of Cerebral Aneurysms Recruiting NCT04236856

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

Brain, Eye, Kidney, Pituitary, Heart, Endothelial, Liver

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 6277)
# Title Authors PMID Year
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm. 61 54
17714769 2007
Management of polycystic liver disease. 61 54
15701294 2005
[In situ localization of mRNA gelatinases in cerebral aneurysms]. 61 54
11715488 1999
Morphometric analysis of reticular and elastin fibers in the cerebral arteries of patients with intracranial aneurysms. 54 61
2362672 1990
Optimization of radiation settings for angiography using 3D fluoroscopy for imaging of intracranial aneurysms. 61
33689512 2021
The dataset on the clipped cerebral aneurysm and their radiological findings in three-dimensional computed tomography, time-of-flight magnetic resonance angiography (TOF-MRA), and Pointwise Encoding Time Reduction with Radial Acquisition (PETRA)-MRA. 61
33665265 2021
Rabbit Elastase Aneurysm: Imaging and Histology Correlates for Inflammation and Healing. 61
33412322 2021
Increased Arterial Stiffness is a Predictor of Delayed Ischaemic Stroke After Subarachnoid Haemorrhage. 61
32896483 2021
Spontaneous rupture of cerebral aneurysm after thrombectomy in a case of acute ischemic stroke with proximal occlusion. 61
33047243 2021
Flow-diverting stent and delayed intracranial bleeding: the case for discussing acquired von Willebrand disease. 61
32406779 2021
Intra-operative fluorescein videoangiography-related nephrotoxicity in intracranial aneurysm surgery: Single center, observational cohort study. 61
33725507 2021
CFD validation using in-vitro MRI velocity data - Methods for data matching and CFD error quantification. 61
33545507 2021
Hydrophilic polymer embolization following flow diversion of cerebral aneurysms. 61
33765885 2021
Anesthetic Management of Patients Undergoing Intravascular Treatment of Cerebral Aneurysms and Arteriovenous Malformations. 61
33563378 2021
Development and clinical evaluation of a contactless operating interface for three-dimensional image-guided navigation for endovascular neurosurgery. 61
33709240 2021
Bronchiectasis and Bronchiolectasis With Severe Herniating Pattern Associated With STAT1 Gain-of-Function Mutation: Detailed Clinicopathological Findings. 61
33439110 2021
A1 Segment Unruptured Aneurysm of Persistent Primitive Olfactory Artery Coexisted with Accessory Middle Cerebral Artery. 61
33784519 2021
Nuisance bleeding complications in patients with cerebral aneurysm treated with Pipeline embolization device. 61
32620576 2021
Cerebral Aneurysm Rupture during Pregnancy Resulting in Subdural Hematoma without Subarachnoid Hemorrhage. 61
33716275 2021
Usefulness of 3 Tesla Ultrashort Echo Time Magnetic Resonance Angiography (UTE-MRA, SILENT-MRA) for Evaluation of the Mother Vessel after Cerebral Aneurysm Clipping: Case Series of 19 Patients. 61
33504734 2021
Cerebral aneurysm rupture status classification using statistical and machine learning methods. 61
33685288 2021
Cerebral aneurysm: De novo genesis and rupture within 15 days. 61
33185958 2021
Retractorless combined pterional and interhemispheric approach to achieve proximal control in pericallosal artery aneurysm: how I do it. 61
33687560 2021
Endovascular Retreatment of Previously Ruptured Coiled Cerebral Aneurysm Remnants Significantly Reduces Rebleed Rate. 61
33352305 2021
Efficacy and safety of flow diverters in posterior circulation aneurysms and comparison with their efficacy in anterior circulation aneurysms: A systematic review and meta-analysis. 61
33752478 2021
Multi-View Convolutional Neural Networks in Rupture Risk Assessment of Small, Unruptured Intracranial Aneurysms. 61
33805171 2021
Rare PTA variant (Saltzman type IIIa) associated with multiple cerebral aneurysms. 61
33653866 2021
Inflow Hemodynamics of Intracranial Aneurysms: A Comparison of Computational Fluid Dynamics and 4D Flow Magnetic Resonance Imaging. 61
33662703 2021
Greek Registry of Cerebral Aneurysms. 61
33540450 2021
Hemodynamic conditions that favor bleb formation in cerebral aneurysms. 61
32680874 2021
Active management of the target P2Y12 reaction unit range in patients undergoing stent-assisted coil embolization for unruptured cerebral aneurysms. 61
33674394 2021
The Prophylactic Use of Tirofiban versus Oral Antiplatelet Medications in Stent-Assisted Coiling of Intracranial Aneurysms: A Meta-analysis. 61
33707284 2021
The Impact of Myeloperoxidase in the Rupturing of Cerebral Aneurysms. 61
33285335 2021
Complete or Partial Parent Artery Sacrifice: Effect of Vessel-Occlusion Strategies on Complete Obliteration of Complex Aneurysms. 61
33340722 2021
Comparative study between minimally invasive supraorbital craniotomy and pterional craniotomy for treating anterior circulation cerebral aneurysms in a low-resource setting. 61
33692472 2021
Corrigendum to "Intraprocedural Rupture of Unruptured Cerebral Aneurysms During Coil Embolization: A Single-Center Experience" [World Neurosurgery 105 (2017) 177-183]. 61
33744167 2021
Staged Approach for Stent-Assisted Coiling of Cerebral Aneurysms after Failure of Initial Intra-Saccular Catheterization. 61
33618505 2021
Enigma of what is Known about Intracranial Aneurysm Occlusion with Endovascular Devices. 61
33774553 2021
Peri-Aneurysmal Brain Edema in Native and Treated Aneurysms: The Role of Thrombosis. 61
33264834 2021
Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Unsuspected Infective Endocarditis. 61
33360518 2021
Progressive cerebral and coronary aneurysms in the original two patients with Kosaki overgrowth syndrome. 61
33382209 2021
Double-barrel STA-MCA bypass for cerebral revascularization: lessons learned from a 10-year experience. 61
33740759 2021
Dual origin of vertebral artery and intimal relationship with spontaneous artery dissection: a case report and systematic review. 61
33420866 2021
Ventricular Assist Device Driveline Infection and Development of Intracranial Hemorrhage: A Case Series. 61
33741789 2021
[Subarachnoid Hemorrhage]. 61
33762441 2021
PD-1+ Monocytes Mediate Cerebral Vasospasm Following Subarachnoid Hemorrhage. 61
33370819 2021
Timing of treatment of aneurysmal subarachnoid haemorrhage: are the goals set in international guidelines achievable? 61
33599919 2021
Periprocedural safety of saccular aneurysm embolization with the Penumbra SMART Coil System: a SMART registry subset analysis. 61
33593799 2021
A comparative study of transradial versus transfemoral approach for flow diversion. 61
33560470 2021
Comparison of PED and FRED flow diverters for posterior circulation aneurysms: a propensity score matched cohort study. 61
32611622 2021

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

Pathways related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
Show member pathways
2 11.51 MMP2 HMOX1
Show member pathways
11.43 MMP2 ELANE
4 11.35 MMP2 HMOX1
5 11.05 MMP2 ELANE
6 10.93 MMP2 HMOX1 ELN
7 10.91 ELN ELANE
8 10.79 MMP2 HMOX1
9 10.16 MMP2 CTSB CST3

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.55 MMP2 ELN ELANE CTSB CST3
2 extracellular space GO:0005615 9.35 MMP2 HMOX1 ELANE CTSB CST3
3 collagen-containing extracellular matrix GO:0062023 8.92 MMP2 ELN ELANE CTSB

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.5 MMP2 ELANE CTSB
2 neutrophil degranulation GO:0043312 9.43 ELANE CTSB CST3
3 extracellular matrix disassembly GO:0022617 9.16 MMP2 ELANE
4 collagen catabolic process GO:0030574 8.96 MMP2 CTSB
5 positive regulation of smooth muscle cell proliferation GO:0048661 8.8 MMP2 HMOX1 ELANE

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.16 ELANE CST3
2 peptidase activity GO:0008233 9.13 MMP2 ELANE CTSB
3 endopeptidase activity GO:0004175 8.8 MMP2 ELANE CTSB

Sources for Cerebral Aneurysms

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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