MCID: CRB086
MIFTS: 44

Cerebral Aneurysms

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 54
Cerebral Aneurysm 55 73
Cerebral Arterial Aneurysm 73

Classifications:



External Ids:

Summaries for Cerebral Aneurysms

NINDS : 54 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and vascular disease. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Degradation of the extracellular matrix and Immune response IL-23 signaling pathway. The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 32.4 ELN MMP2
2 vascular disease 31.3 CCL2 CST3 ELANE ELN MPO
3 autosomal dominant polycystic kidney disease 29.6 CCL2 CST3
4 myocardial infarction 29.0 CCL2 CST3 MMP2 MPO
5 aortic aneurysm, familial abdominal, 1 28.6 CCL2 CST3 ELANE ELN MMP2
6 intracranial berry aneurysm 11.7
7 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.3
8 loeys-dietz syndrome 4 11.1
9 familial cerebral saccular aneurysm 10.3
10 thrombosis 10.2
11 kidney disease 10.1
12 polycystic kidney disease 10.1
13 mid-dermal elastolysis 10.1 ELANE ELN
14 elephantiasis 10.1 ELANE ELN
15 peripheral artery disease 10.1 CCL2 CST3
16 arteriovenous malformation 10.1
17 headache 10.1
18 alpha-1-antitrypsin deficiency 10.1 ELANE ELN
19 chorioamnionitis 10.1 CCL2 ELANE
20 acute proliferative glomerulonephritis 10.1 CCL2 MPO
21 proliferative glomerulonephritis 10.1 CCL2 MPO
22 glomerulonephritis 10.1 CCL2 MPO
23 bacterial pneumonia 10.1 ELANE ELN
24 pulmonary emphysema 10.1 ELANE ELN
25 ascending cholangitis 10.1 CCL2 MPO
26 adult respiratory distress syndrome 10.1 ELANE ELN
27 idiopathic interstitial pneumonia 10.1 CCL2 ELANE
28 endocarditis 10.1
29 ischemia 10.1
30 aortic coarctation 10.1
31 pelvic inflammatory disease 10.1 CCL2 MPO
32 crescentic glomerulonephritis 10.1 CCL2 MPO
33 pleurisy 10.1 CCL2 MPO
34 extrinsic allergic alveolitis 10.0 CCL2 MPO
35 pasteurellosis 10.0 ELANE MPO
36 urinary system disease 10.0 CCL2 CST3
37 hydrocephalus 10.0
38 rapidly progressive glomerulonephritis 10.0 ELANE MPO
39 bronchopneumonia 10.0 ELANE MPO
40 vulvitis 10.0 ELANE MPO
41 periodontosis 10.0 ELANE MPO
42 aleukemic leukemia cutis 10.0 ELANE MPO
43 kawasaki disease 10.0 CCL2 ELANE
44 peritonitis 10.0 CCL2 MPO
45 fibromuscular dysplasia 10.0
46 senile ectropion 10.0 ELN MMP2
47 bronchiectasis 10.0 ELANE MPO
48 granulomatosis with polyangiitis 10.0 ELANE MPO
49 bacterial infectious disease 10.0 CCL2 ELANE
50 sorsby fundus dystrophy 10.0 ELN MMP2

Graphical network of the top 20 diseases related to Cerebral Aneurysms:



Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 118)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 1 50-78-2 2244
2
Clopidogrel Approved Phase 4,Phase 3 113665-84-2, 120202-66-6 60606
3
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
4
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
5 Analgesics Phase 4,Phase 3,Phase 1,Not Applicable
6 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Not Applicable
7 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
8 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 1
9 Anti-Asthmatic Agents Phase 4
10 Autonomic Agents Phase 4
11 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 1
12 Antirheumatic Agents Phase 4,Phase 3,Phase 1
13 Respiratory System Agents Phase 4
14 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 1,Not Applicable
15 Antipyretics Phase 4,Phase 3,Phase 1
16 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
17 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
18 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
19 Vasodilator Agents Phase 4,Phase 1,Phase 2
20 Bronchodilator Agents Phase 4
21 Cytochrome P-450 CYP2C19 Inhibitors Phase 4,Phase 3
22 Phosphodiesterase 3 Inhibitors Phase 4
23 Prasugrel hydrochloride Phase 4 389574-19-0
24 Protective Agents Phase 4
25 Phosphodiesterase Inhibitors Phase 4,Phase 2
26 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
27 Neuroprotective Agents Phase 4
28 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3
29 Purinergic P2 Receptor Antagonists Phase 4,Phase 3
30 Hematinics Phase 4
31 Epoetin alfa Phase 4 113427-24-0
32
Sevoflurane Approved, Vet_approved Phase 3,Phase 2 28523-86-6 5206
33
Propofol Approved, Investigational, Vet_approved Phase 3,Phase 2 2078-54-8 4943
34
Esmolol Approved Phase 3 103598-03-4, 81147-92-4 59768
35
Ticagrelor Approved Phase 3 274693-27-5 9871419
36 Anesthetics Phase 3,Phase 2,Phase 1,Not Applicable
37 Central Nervous System Depressants Phase 3,Phase 2,Phase 1,Not Applicable
38 Hypnotics and Sedatives Phase 3,Phase 2,Not Applicable
39 Adrenergic Agents Phase 3,Not Applicable
40 Anesthetics, Intravenous Phase 3,Phase 2
41 Adrenergic Antagonists Phase 3
42 Adrenergic beta-Antagonists Phase 3
43 Adrenergic beta-1 Receptor Antagonists Phase 3
44 Anesthetics, Inhalation Phase 3,Phase 2
45 Anesthetics, General Phase 3,Phase 2
46
Clevidipine Approved, Investigational Phase 2 167221-71-8
47 tannic acid Approved Phase 1, Phase 2,Not Applicable
48
Benzocaine Approved, Investigational Phase 1, Phase 2,Not Applicable 94-09-7, 1994-09-7 2337
49 Estradiol valerate Approved, Investigational, Vet_approved Phase 2 979-32-8
50
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757

Interventional clinical trials:

(show top 50) (show all 88)
# Name Status NCT ID Phase Drugs
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
2 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
3 Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm Recruiting NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
4 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
5 Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
6 Esmolol Infusion in Patients Undergoing Craniotomy Completed NCT02455440 Phase 3 Esmolol;Placebo;Propofol and sevoflurane
7 Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
8 The Tilburg Vasospasm Study Terminated NCT01407614 Phase 2, Phase 3
9 Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH) Unknown status NCT02011321 Phase 2 clevidipine
10 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
11 Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
12 Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
13 Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial Recruiting NCT01895881 Phase 2 Estradiol;Placebo
14 Sevoflurane in Subarachnoidal Haemorrhage Recruiting NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
15 Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
16 Deferiprone for Ruptured Brain Aneurysm Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
17 Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage Terminated NCT02176837 Phase 2 Sodium Nitrite
18 Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm Withdrawn NCT00871065 Phase 2 Sildenafil citrate
19 Sildenafil for Prevention of Cerebral Vasospasm Withdrawn NCT01091870 Phase 2 Placebo;Sildenafil Citrate, 25 mg, 3 times a day.;Sildenafil Citrate 50 mg, 3 times a day
20 Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01878136 Phase 1, Phase 2 Tissue Plasminogen Activator
21 Aspirin Attenuates Inflammation in Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
22 Stellate Ganglion Block Using Ultrasound Guidance For Treatment Of Post Clipping Cerebral Vasospasm Completed NCT02775318 Phase 1 Bupivacaine
23 Remote Ischemic Preconditioning in Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
24 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520 Not Applicable
25 Screening Intracranial Aneurysms With Magnetic Resonance Angiography (MRA) in China Unknown status NCT00926172
26 Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity Unknown status NCT02700607 Not Applicable Intravenous Crystalloid;Intravenous HES
27 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395 Not Applicable
28 Remote Ischemic Preconditioning for Intracranial Aneurysm Treatment Unknown status NCT02162654 Not Applicable
29 Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia Unknown status NCT01460563 Not Applicable Magnesium Sulfate;0.9% saline;0.9% saline
30 Registry for Study of Coils in Intracranial Aneurysms Unknown status NCT01000675
31 Multicenter Retrospective Registry of Anterior Communicating Artery Aneurysms With Endovascular Therapy Unknown status NCT02444832
32 Contrast-free Magnetic Resonance Angiography (MRA) at 3.0 T for Intracranial Aneurysm Detection Unknown status NCT01031147
33 Effect of Acupuncture on Inflammation and Immune Function After Craniotomy Unknown status NCT02761096 Not Applicable
34 Long-term Clinico-radiological Evolution of Patients With Brain Lesions During Infectious Endocarditis Unknown status NCT02252900 Not Applicable
35 Chinese Small Intracranial Aneurysm Study (CSIAS) Unknown status NCT02948504
36 Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02915380
37 Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Completed NCT02700126
38 Use of Classic LMA During Endovascular Therapy Completed NCT03288519
39 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395
40 Surgical Theater's Surgery Rehearsal Platform Completed NCT02099318 Not Applicable
41 DELTA Trial: Does Embolization With Larger Coils Lead to Better Treatment of Aneurysms Trial Completed NCT01943591 Not Applicable
42 EEG Monitoring to Assess Emergence From Neuroanesthesia Completed NCT00443807 Not Applicable
43 Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage Completed NCT00962546
44 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
45 Hypothalamo-, Pituitary-, Adrenal Axis Dysfunction in Subarachnoid Hemorrhage Completed NCT00614887
46 Genetic Analysis of Familial Brain Aneurysms Completed NCT00011856
47 Amnesia After Surgery for Anterior Communicating Aneurysm: High Resolution Magnetic Resonance (MR) Imaging Findings Completed NCT01919775
48 Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients Completed NCT02864940 Not Applicable
49 Cerebral Autoregulation and Vasospasm in Patients With TBI Completed NCT02351518
50 Quality of Life in Elderly After Aneurysmal Subarachnoid Hemorrhage (SAH) Completed NCT00692744

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

41
Brain, Testes, Eye, Heart, Kidney, Lung, Endothelial

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 1914)
# Title Authors Year
1
Neutrophilic Ribonucleic Acid Expression as a Clinical Tool in Detecting Cerebral Aneurysms. ( 30395290 )
2019
2
Secondary coiling after incomplete surgical clipping of cerebral aneurysms: a rescue strategy or a treatment option for complex cases? Institutional series and systematic review. ( 29417290 )
2018
3
Differences in Pressure Within the Sac of Human Ruptured and Nonruptured Cerebral Aneurysms. ( 29741656 )
2018
4
Endovascular treatment of cerebral aneurysm after renal transplantation in polycystic kidney disease. ( 29444616 )
2018
5
Hemodynamic characteristics of hyperplastic remodeling lesions in cerebral aneurysms. ( 29338059 )
2018
6
Higher leukocyte count predicts 3-month poor outcome of ruptured cerebral aneurysms. ( 29643435 )
2018
7
Application of PHASES and ELAPSS scores to ruptured cerebral aneurysms: how many would have been conservatively managed? ( 29808636 )
2018
8
Effect of Local Coil Density on Blood Flow Stagnation in Densely Coiled Cerebral Aneurysms: A Computational Study Using a Cartesian Grid Method. ( 29383379 )
2018
9
Thromboembolic complications during endovascular treatment of ruptured cerebral aneurysms. ( 29125027 )
2018
10
The dynamic natural history of cerebral aneurysms from cardiac myxomas: A review of the natural history of myxomatous aneurysms. ( 29383976 )
2018
11
Cerebral Aneurysms in Judicial Precedents. ( 29631385 )
2018
12
Coadjuvant Treatment of Vasospasm in Ruptured Unsecured Cerebral Aneurysms with Aggressive Angioplasty, Intra-Arterial Nimodipine, and Aneurysm Embolization. ( 29753899 )
2018
13
In vitro measurement of the permeability of endovascular coils deployed in cerebral aneurysms. ( 29298858 )
2018
14
Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study. ( 29622372 )
2018
15
Teaching NeuroImages: A cutaneous vascular malformation hides giant cerebral aneurysms. ( 29632121 )
2018
16
Rehabilitation after Clipping of Cerebral Aneurysms without Acute Subarachnoid Hemorrhage: Outcome Analysis of 100 Consecutive Cases. ( 29890540 )
2018
17
Evaluation of Microsurgery for Managing Giant or Complex Cerebral Aneurysms: A Retrospective Study. ( 29653272 )
2018
18
Quantitative proteomics analysis of differentially expressed proteins in ruptured and unruptured cerebral aneurysms by iTRAQ. ( 29729990 )
2018
19
Nickel-Related Adverse Reactions in the Treatment of Cerebral Aneurysms: A Literature Review. ( 29684517 )
2018
20
Thrombosis in Cerebral Aneurysms and the Computational Modeling Thereof: A Review. ( 29670533 )
2018
21
Safety Assessment of Endovascular Treatment of Cerebral Aneurysms in Patients with Fibromuscular Dysplasia. ( 29628950 )
2018
22
Association of plasma D-dimer level with thromboembolic events after endovascular coil treatment of ruptured cerebral aneurysms. ( 29424648 )
2018
23
What is the current role of bypass surgery in the management of cerebral aneurysms? ( 29766916 )
2018
24
Intraoperative Assessment of Cortical Perfusion After Intracranial-To-Intracranial and Extracranial-To-Intracranial Bypass for Complex Cerebral Aneurysms Using Flow 800. ( 29897545 )
2018
25
Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm. ( 29977363 )
2018
26
The Successful Use of Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and a Pituitary Lesion. ( 29952859 )
2018
27
Phase-contrast MRI versus numerical simulation to quantify hemodynamical changes in cerebral aneurysms after flow diverter treatment. ( 29304062 )
2018
28
Pharmacy-Mediated Antiplatelet Management Protocol Compared to One-time Platelet Function Testing Prior to Pipeline Embolization of Cerebral Aneurysms: A Propensity Score-Matched Cohort Study. ( 29608747 )
2018
29
Cyclic Mechanical Stretch Induced Smooth Muscle Cell Changes in Cerebral Aneurysm Progress by Reducing Collagen Type IV and Collagen Type VI Levels. ( 29439246 )
2018
30
Flow Diversion of Posterior Circulation Cerebral Aneurysms: A Single-Institution Series of 59 Cases. ( 29608702 )
2018
31
Stent-assisted coiling of cerebral aneurysms with the Neuroform Atlas stent. ( 29350091 )
2018
32
Postoperative Subdural Air Collection Is a Risk Factor for Chronic Subdural Hematoma after Surgical Clipping of Cerebral Aneurysms. ( 29760311 )
2018
33
Neoplastic cerebral aneurysm from metastatic lung adenocarcinoma with neuroendocrine features. ( 30399471 )
2018
34
Cerebral Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Comparison of Management Approaches. ( 30060240 )
2018
35
Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone: Preliminary Results. ( 30465954 )
2018
36
Letter to the Editor. How does size ratio affect the clinical result of open surgery for cerebral aneurysms? ( 30497187 )
2018
37
Convolutional Neural Networks for the Detection and Measurement of Cerebral Aneurysms on Magnetic Resonance Angiography. ( 30511281 )
2018
38
Endoscopic endonasal clipping of cerebral aneurysms: started from the bottom, now we here! ( 30514072 )
2018
39
Parent Artery Occlusion for Unruptured Cerebral Aneurysms: Results of the Japanese Registry of Neuroendovascular Therapy 3. ( 30531152 )
2018
40
Scalp nerves block for surgical clipping of cerebral aneurysms in patients allergic to nonsteroidal anti-inflammatory drugs. ( 30553223 )
2018
41
Safety results from the treatment of 109 cerebral aneurysms using the Woven EndoBridge technique: preliminary results in the United Kingdom. ( 28156251 )
2018
42
Association of hypothyroidism with unruptured cerebral aneurysms: a case-control study. ( 28298012 )
2018
43
Predisposing factors for recanalization of cerebral aneurysms after endovascular embolization: a multivariate study. ( 28377443 )
2018
44
Deep neural network-based computer-assisted detection of cerebral aneurysms in MR angiography. ( 28836310 )
2018
45
Relationship between patient safety indicator events and comprehensive stroke center volume status in the treatment of unruptured cerebral aneurysms. ( 29053070 )
2018
46
Tiny Cerebral Aneurysms Can Be Treated Safely and Effectively with Low-Profile Visualized Intraluminal Support Stent-Assisted Coiling or Coiling Alone. ( 29458185 )
2018
47
Letter to the Editor. Role of dysplastic and genetic mutations during the formation of cerebral aneurysms in infants. ( 29498603 )
2018
48
Letter to the Editor. Intraoperative aneurysm rupture during awake clipping of cerebral aneurysms. ( 29570014 )
2018
49
Feasibility of endoscopic endonasal approach for clip application of cerebral aneurysms: a systematic review. ( 29582975 )
2018
50
Rescue Therapy for Procedural Complications Associated With Deployment of Flow-Diverting Devices in Cerebral Aneurysms. ( 29584923 )
2018

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

Pathways related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 ELANE ELN MMP2
2
Show member pathways
12.14 CCL2 MMP2 MPO
3
Show member pathways
11.79 CCL2 ELN MMP2
4 11.6 CCL2 MMP2
5 11.53 CCL2 MMP2
6
Show member pathways
11.52 ELANE MMP2
7 11.44 CCL2 MMP2
8 11.37 ELANE MPO
9 11 ELANE ELN
10 10.93 CCL2 ELN MMP2
11 10.9 CCL2 MMP2
12 10.83 CCL2 MMP2
13 10.62 CST3 MMP2
14 10.48 ELANE MMP2 MPO
15 10.36 CCL2 MPO

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 CCL2 CST3 ELANE MMP2 MPO
2 collagen-containing extracellular matrix GO:0062023 9.33 ELANE ELN MMP2
3 secretory granule GO:0030141 9.32 ELANE MPO
4 azurophil granule lumen GO:0035578 9.26 ELANE MPO
5 extracellular region GO:0005576 9.1 CCL2 CST3 ELANE ELN MMP2 MPO

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.5 CST3 ELANE MPO
2 animal organ morphogenesis GO:0009887 9.37 CCL2 ELN
3 extracellular matrix disassembly GO:0022617 9.26 ELANE MMP2
4 defense response to fungus GO:0050832 9.16 ELANE MPO
5 negative regulation of growth of symbiont in host GO:0044130 8.96 ELANE MPO
6 response to yeast GO:0001878 8.62 ELANE MPO

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 CST3 ELANE

Sources for Cerebral Aneurysms

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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