MCID: CRB086
MIFTS: 44

Cerebral Aneurysms

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 55
Cerebral Aneurysm 56 74
Cerebral Arterial Aneurysm 74

Classifications:



External Ids:

Summaries for Cerebral Aneurysms

NINDS : 55 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and vascular disease. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Degradation of the extracellular matrix and Immune response IL-23 signaling pathway. The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 32.5 ELN MMP2
2 vascular disease 30.7 CCL2 CST3 ELANE ELN MPO
3 autosomal dominant polycystic kidney disease 29.6 CCL2 CST3
4 aortic aneurysm, familial abdominal, 1 28.7 CCL2 CST3 ELANE ELN MMP2
5 myocardial infarction 28.7 CCL2 CST3 MMP2 MPO
6 intracranial berry aneurysm 11.7
7 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.3
8 loeys-dietz syndrome 4 11.1
9 familial cerebral saccular aneurysm 10.3
10 thrombosis 10.3
11 kidney disease 10.2
12 polycystic kidney disease 10.2
13 arteriovenous malformation 10.2
14 mid-dermal elastolysis 10.1 ELANE ELN
15 elephantiasis 10.1 ELANE ELN
16 erysipelas 10.1 ELANE ELN
17 peripheral artery disease 10.1 CCL2 CST3
18 aortic coarctation 10.1
19 headache 10.1
20 chorioamnionitis 10.1 CCL2 ELANE
21 alpha-1-antitrypsin deficiency 10.1 ELANE ELN
22 endocarditis 10.1
23 ischemia 10.1
24 pulmonary emphysema 10.1 ELANE ELN
25 adult respiratory distress syndrome 10.1 ELANE ELN
26 idiopathic interstitial pneumonia 10.1 CCL2 ELANE
27 senile ectropion 10.1 ELN MMP2
28 hydrocephalus 10.1
29 sorsby fundus dystrophy 10.1 ELN MMP2
30 aortic aneurysm, familial thoracic 1 10.0 ELN MMP2
31 pneumothorax 10.0 ELN MMP2
32 urinary system disease 10.0 CCL2 CST3
33 aortic disease 10.0 ELN MMP2
34 varicose veins 10.0 ELN MMP2
35 inguinal hernia 10.0 ELN MMP2
36 fibromuscular dysplasia 10.0
37 epilepsy 10.0
38 kawasaki disease 10.0 CCL2 ELANE
39 marfan syndrome 10.0 ELN MMP2
40 acute proliferative glomerulonephritis 10.0 CCL2 MPO
41 proliferative glomerulonephritis 10.0 CCL2 MPO
42 glomerulonephritis 10.0 CCL2 MPO
43 ascending cholangitis 10.0 CCL2 MPO
44 lymphangioleiomyomatosis 10.0 ELN MMP2
45 crescentic glomerulonephritis 10.0 CCL2 MPO
46 pleurisy 10.0 CCL2 MPO
47 periodontitis 10.0 CCL2 MMP2
48 takayasu arteritis 9.9
49 moyamoya disease 1 9.9
50 brittle bone disorder 9.9

Graphical network of the top 20 diseases related to Cerebral Aneurysms:



Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 130)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 1 50-78-2 2244
2
Clopidogrel Approved Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
3
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
4 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Not Applicable
5 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
6 Analgesics Phase 4,Phase 3,Phase 1,Not Applicable
7 Vasodilator Agents Phase 4,Phase 1,Phase 2
8 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
9 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 1
11 Anti-Asthmatic Agents Phase 4
12 Autonomic Agents Phase 4
13 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 1
14 Antipyretics Phase 4,Phase 3,Phase 1
15 Bronchodilator Agents Phase 4
16 Respiratory System Agents Phase 4
17 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Antirheumatic Agents Phase 4,Phase 3,Phase 1
19 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 1,Not Applicable
20 Prasugrel hydrochloride Phase 4 389574-19-0
21 Purinergic P2 Receptor Antagonists Phase 4,Phase 3
22 Phosphodiesterase 3 Inhibitors Phase 4
23 Neuroprotective Agents Phase 4
24 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3
25 Phosphodiesterase Inhibitors Phase 4,Phase 2
26 Protective Agents Phase 4
27 Hematinics Phase 4,Phase 3
28 Epoetin alfa Phase 4 113427-24-0
29
Esmolol Approved Phase 3 103598-03-4, 81147-92-4 59768
30
Propofol Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 2078-54-8 4943
31
Sevoflurane Approved, Vet_approved Phase 3,Phase 2,Not Applicable 28523-86-6 5206
32
Ticagrelor Approved Phase 3 274693-27-5 9871419
33
Iron Approved, Experimental Phase 3,Phase 2 7439-89-6, 15438-31-0 23925 27284
34 Central Nervous System Depressants Phase 3,Phase 2,Phase 1,Not Applicable
35 Anesthetics Phase 3,Phase 2,Phase 1,Not Applicable
36 Pharmaceutical Solutions Phase 3,Phase 1,Phase 2
37 Adrenergic Antagonists Phase 3
38 Adrenergic beta-Antagonists Phase 3
39 Anesthetics, Inhalation Phase 3,Phase 2,Not Applicable
40 Anesthetics, Intravenous Phase 3,Phase 2,Not Applicable
41 Adrenergic beta-1 Receptor Antagonists Phase 3
42 Hypnotics and Sedatives Phase 3,Phase 2,Not Applicable
43 Anesthetics, General Phase 3,Phase 2,Not Applicable
44 Adrenergic Agents Phase 3,Not Applicable
45 Trace Elements Phase 3
46 Ferric Compounds Phase 3
47 Nutrients Phase 3
48 Micronutrients Phase 3
49
Clevidipine Approved, Investigational Phase 2 167221-71-8
50
tannic acid Approved Phase 1, Phase 2,Not Applicable 1401-55-4

Interventional clinical trials:

(show top 50) (show all 93)
# Name Status NCT ID Phase Drugs
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
2 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
3 Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm Recruiting NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
4 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
5 Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
6 Esmolol Infusion in Patients Undergoing Craniotomy Completed NCT02455440 Phase 3 Esmolol;Placebo;Propofol and sevoflurane
7 Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
8 Intravenous Iron Infusion With Ferric Carboxymaltose in Patients With Heart Failure and Iron Deficiency Not yet recruiting NCT03871699 Phase 3 Ferric carboxymaltose
9 The Tilburg Vasospasm Study Terminated NCT01407614 Phase 2, Phase 3
10 Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH) Unknown status NCT02011321 Phase 2 clevidipine
11 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
12 Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
13 Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
14 Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial Recruiting NCT01895881 Phase 2 Estradiol;Placebo
15 Sevoflurane in Subarachnoidal Haemorrhage Recruiting NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
16 Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
17 Deferiprone for Ruptured Brain Aneurysm Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
18 Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage Terminated NCT02176837 Phase 2 Sodium Nitrite
19 Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm Withdrawn NCT00871065 Phase 2 Sildenafil citrate
20 Sildenafil for Prevention of Cerebral Vasospasm Withdrawn NCT01091870 Phase 2 Placebo;Sildenafil Citrate, 25 mg, 3 times a day.;Sildenafil Citrate 50 mg, 3 times a day
21 Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01878136 Phase 1, Phase 2 Tissue Plasminogen Activator
22 Aspirin Attenuates Inflammation in Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
23 Stellate Ganglion Block Using Ultrasound Guidance For Treatment Of Post Clipping Cerebral Vasospasm Completed NCT02775318 Phase 1 Bupivacaine
24 Remote Ischemic Preconditioning in Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
25 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520 Not Applicable
26 Screening Intracranial Aneurysms With Magnetic Resonance Angiography (MRA) in China Unknown status NCT00926172
27 Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity Unknown status NCT02700607 Not Applicable Intravenous Crystalloid;Intravenous HES
28 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395 Not Applicable
29 Remote Ischemic Preconditioning for Intracranial Aneurysm Treatment Unknown status NCT02162654 Not Applicable
30 Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia Unknown status NCT01460563 Not Applicable Magnesium Sulfate;0.9% saline;0.9% saline
31 Registry for Study of Coils in Intracranial Aneurysms Unknown status NCT01000675
32 Multicenter Retrospective Registry of Anterior Communicating Artery Aneurysms With Endovascular Therapy Unknown status NCT02444832
33 Contrast-free Magnetic Resonance Angiography (MRA) at 3.0 T for Intracranial Aneurysm Detection Unknown status NCT01031147
34 Long-term Clinico-radiological Evolution of Patients With Brain Lesions During Infectious Endocarditis Unknown status NCT02252900 Not Applicable
35 Chinese Small Intracranial Aneurysm Study (CSIAS) Unknown status NCT02948504
36 Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02915380
37 Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02995928 Not Applicable
38 Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Completed NCT02700126
39 Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients Completed NCT02507999 Not Applicable
40 Use of Classic LMA During Endovascular Therapy Completed NCT03288519
41 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395
42 Surgical Theater's Surgery Rehearsal Platform Completed NCT02099318 Not Applicable
43 DELTA Trial: Does Embolization With Larger Coils Lead to Better Treatment of Aneurysms Trial Completed NCT01943591 Not Applicable
44 EEG Monitoring to Assess Emergence From Neuroanesthesia Completed NCT00443807 Not Applicable
45 Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage Completed NCT00962546
46 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
47 Hypothalamo-, Pituitary-, Adrenal Axis Dysfunction in Subarachnoid Hemorrhage Completed NCT00614887
48 Risk Factors of Middle Cerebral Artery Aneurysm. Completed NCT03493035
49 Genetic Analysis of Familial Brain Aneurysms Completed NCT00011856
50 Amnesia After Surgery for Anterior Communicating Aneurysm: High Resolution Magnetic Resonance (MR) Imaging Findings Completed NCT01919775

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

42
Brain, Testes, Eye, Heart, Kidney, Pituitary, Endothelial

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 2451)
# Title Authors Year
1
Relationships of Statins Therapy and Hyperlipidemia with the Incidence, Rupture, Post-repair Mortality and All-cause Mortality of Abdominal Aortic Aneurysm and Cerebral Aneurysm: A Meta-analysis and Systematic Review. ( 30688798 )
2019
2
Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone: Preliminary Results. ( 30465954 )
2019
3
Parent Artery Occlusion for Unruptured Cerebral Aneurysms: Results of the Japanese Registry of Neuroendovascular Therapy 3. ( 30531152 )
2019
4
Stent-assisted coiling of cerebral aneurysms using the Y-stenting technique: a systematic review and meta-analysis. ( 30610070 )
2019
5
Persistent Primitive Hypoglossal Artery Associated With Multiple Cerebral Aneurysms. ( 30627281 )
2019
6
Cerebral Aneurysms: Are They Associated with Anatomic Variations of Carotid and Main Cerebral Arteries? ( 30639500 )
2019
7
Development of a stent capable of the controlled release of basic fibroblast growth factor and argatroban to treat cerebral aneurysms: In vitro experiment and evaluation in a rabbit aneurysm model. ( 30653829 )
2019
8
Transradial approach for flow diversion treatment of cerebral aneurysms: a multicenter study. ( 30670622 )
2019
9
Quantification of hemodynamic irregularity using oscillatory velocity index in the associations with the rupture status of cerebral aneurysms. ( 30670624 )
2019
10
Delayed Treatment (≥5 Days) by Flow Diversion of Ruptured Blister-Like Cerebral Aneurysms : Case Series of 8 Consecutive Patients. ( 30683969 )
2019
11
Rupture risk of small unruptured cerebral aneurysms. ( 30684948 )
2019
12
A Phantom Menace to Medical Personnel During Endovascular Treatment of Cerebral Aneurysms: Real-Time Measurement of Radiation Exposure During Procedures. ( 30685367 )
2019
13
The effect of hospital safety-net burden on outcomes, cost, and reportable quality metrics after emergent clipping and coiling of ruptured cerebral aneurysms. ( 30797220 )
2019
14
Low-dose Prasugrel in Patients with Resistance to Clopidogrel for the Treatment of Cerebral Aneurysms: Follow-up of over 6 Months. ( 30827067 )
2019
15
Differentially expressed genes associated with the estrogen receptor pathway in cerebral aneurysms. ( 30831289 )
2019
16
How definitive treatment affects the rupture rate of unruptured cerebral aneurysms: a competing risk survival analysis. ( 30849750 )
2019
17
Editorial. Assessment of the natural history of cerebral aneurysms in the setting of competing risk. ( 30849764 )
2019
18
HoTPiG: a novel graph-based 3-D image feature set and its applications to computer-assisted detection of cerebral aneurysms and lung nodules. ( 30859456 )
2019
19
Image-Based Modeling of Blood Flow in Cerebral Aneurysms Treated with Intrasaccular Flow Diverting Devices. ( 30891958 )
2019
20
Giant cerebral aneurysm in a patient with Cowden syndrome treated with surgical clipping; a case report. ( 30904793 )
2019
21
A case of posterior reversible encephalopathy syndrome after surgical clipping of unruptured cerebral aneurysm. ( 30660882 )
2019
22
Hepatitis B virus infected patients show increased risk of cerebral aneurysm rupture: A retrospective analysis. ( 30850179 )
2019
23
MRI Screening for Cerebral Aneurysm in Adult Polycystic Kidney Disease: Is the Money Worth Spending? ( 30801234 )
2019
24
Subarachnoid Hemorrhage in the Setting of Electroconvulsive Therapy in a Patient With an Unsecured Cerebral Aneurysm: A Case Report and Review of the Literature. ( 30720550 )
2019
25
Application of second-generation Shikani optical stylet in critically ill patients undergoing cerebral aneurysm embolization. ( 30727794 )
2019
26
Alternative definitions of cerebral aneurysm morphological parameters have an impact on rupture risk determination. ( 30794982 )
2019
27
Lyophilizing thrombin powder-based treatment for hemostasis during coil embolization of ruptured cerebral aneurysm: Two case reports. ( 30803339 )
2019
28
Leptomeningeal carcinomatosis following neoplastic cerebral aneurysm rupture: a case report. ( 30822576 )
2019
29
A cerebral aneurysm arising from a variant posterior communicating artery lying lateral to the oculomotor nerve. ( 30876995 )
2019
30
Rupture of Thrombosed Cerebral Aneurysm During Antithrombotic Therapy for Ischemic Stroke: Case Report and Literature Review. ( 30898732 )
2019
31
Spontaneous acute subdural hematoma. An unusual presentation of ruptured cerebral aneurysm. ( 29655521 )
2019
32
Secondary coiling after incomplete surgical clipping of cerebral aneurysms: a rescue strategy or a treatment option for complex cases? Institutional series and systematic review. ( 29417290 )
2018
33
Differences in Pressure Within the Sac of Human Ruptured and Nonruptured Cerebral Aneurysms. ( 29741656 )
2018
34
Endovascular treatment of cerebral aneurysm after renal transplantation in polycystic kidney disease. ( 29444616 )
2018
35
Hemodynamic characteristics of hyperplastic remodeling lesions in cerebral aneurysms. ( 29338059 )
2018
36
Higher leukocyte count predicts 3-month poor outcome of ruptured cerebral aneurysms. ( 29643435 )
2018
37
Application of PHASES and ELAPSS scores to ruptured cerebral aneurysms: how many would have been conservatively managed? ( 29808636 )
2018
38
Effect of Local Coil Density on Blood Flow Stagnation in Densely Coiled Cerebral Aneurysms: A Computational Study Using a Cartesian Grid Method. ( 29383379 )
2018
39
Thromboembolic complications during endovascular treatment of ruptured cerebral aneurysms. ( 29125027 )
2018
40
The dynamic natural history of cerebral aneurysms from cardiac myxomas: A review of the natural history of myxomatous aneurysms. ( 29383976 )
2018
41
Cerebral Aneurysms in Judicial Precedents. ( 29631385 )
2018
42
Coadjuvant Treatment of Vasospasm in Ruptured Unsecured Cerebral Aneurysms with Aggressive Angioplasty, Intra-Arterial Nimodipine, and Aneurysm Embolization. ( 29753899 )
2018
43
In vitro measurement of the permeability of endovascular coils deployed in cerebral aneurysms. ( 29298858 )
2018
44
Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study. ( 29622372 )
2018
45
Teaching NeuroImages: A cutaneous vascular malformation hides giant cerebral aneurysms. ( 29632121 )
2018
46
Rehabilitation after Clipping of Cerebral Aneurysms without Acute Subarachnoid Hemorrhage: Outcome Analysis of 100 Consecutive Cases. ( 29890540 )
2018
47
Evaluation of Microsurgery for Managing Giant or Complex Cerebral Aneurysms: A Retrospective Study. ( 29653272 )
2018
48
Quantitative proteomics analysis of differentially expressed proteins in ruptured and unruptured cerebral aneurysms by iTRAQ. ( 29729990 )
2018
49
Nickel-Related Adverse Reactions in the Treatment of Cerebral Aneurysms: A Literature Review. ( 29684517 )
2018
50
Thrombosis in Cerebral Aneurysms and the Computational Modeling Thereof: A Review. ( 29670533 )
2018

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

Pathways related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 ELANE ELN MMP2
2
Show member pathways
12.14 CCL2 MMP2 MPO
3
Show member pathways
11.79 CCL2 ELN MMP2
4 11.6 CCL2 MMP2
5 11.54 CCL2 MMP2
6
Show member pathways
11.52 ELANE MMP2
7 11.44 CCL2 MMP2
8 11.37 ELANE MPO
9 11 ELANE ELN
10 10.93 CCL2 ELN MMP2
11 10.9 CCL2 MMP2
12 10.83 CCL2 MMP2
13 10.62 CST3 MMP2
14 10.48 ELANE MMP2 MPO
15 10.36 CCL2 MPO

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 CCL2 CST3 ELANE MMP2 MPO
2 collagen-containing extracellular matrix GO:0062023 9.33 ELANE ELN MMP2
3 secretory granule GO:0030141 9.32 ELANE MPO
4 azurophil granule lumen GO:0035578 9.26 ELANE MPO
5 extracellular region GO:0005576 9.1 CCL2 CST3 ELANE ELN MMP2 MPO

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.5 CST3 ELANE MPO
2 animal organ morphogenesis GO:0009887 9.37 CCL2 ELN
3 extracellular matrix disassembly GO:0022617 9.26 ELANE MMP2
4 defense response to fungus GO:0050832 9.16 ELANE MPO
5 negative regulation of growth of symbiont in host GO:0044130 8.96 ELANE MPO
6 response to yeast GO:0001878 8.62 ELANE MPO

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 CST3 ELANE

Sources for Cerebral Aneurysms

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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