MCID: CRB086
MIFTS: 45

Cerebral Aneurysms

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 55
Cerebral Aneurysm 56 74
Cerebral Arterial Aneurysm 74

Classifications:



External Ids:

Summaries for Cerebral Aneurysms

NINDS : 55 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and vascular disease. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Immune response IL-23 signaling pathway and Degradation of the extracellular matrix. The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and heart, and related phenotype is immune system.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 221)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 32.6 ELN MMP2
2 vascular disease 31.2 CCL2 ELANE ELN MPO
3 aortic aneurysm, familial abdominal, 1 29.2 CCL2 ELANE ELN MMP2
4 myocardial infarction 28.8 CCL2 MMP2 MPO
5 intracranial berry aneurysm 11.7
6 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.3
7 loeys-dietz syndrome 4 11.2
8 familial cerebral saccular aneurysm 10.3
9 arteriovenous malformation 10.3
10 thrombosis 10.3
11 kidney disease 10.2
12 polycystic kidney disease 10.2
13 mid-dermal elastolysis 10.1 ELANE ELN
14 elephantiasis 10.1 ELANE ELN
15 aortic coarctation 10.1
16 headache 10.1
17 erysipelas 10.1 ELANE ELN
18 endocarditis 10.1
19 ischemia 10.1
20 chorioamnionitis 10.1 CCL2 ELANE
21 alpha-1-antitrypsin deficiency 10.1 ELANE ELN
22 pulmonary emphysema 10.1 ELANE ELN
23 adult respiratory distress syndrome 10.1 ELANE ELN
24 idiopathic interstitial pneumonia 10.1 CCL2 ELANE
25 senile ectropion 10.1 ELN MMP2
26 hydrocephalus 10.1
27 sorsby fundus dystrophy 10.1 ELN MMP2
28 aortic aneurysm, familial thoracic 1 10.0 ELN MMP2
29 pneumothorax 10.0 ELN MMP2
30 aortic disease 10.0 ELN MMP2
31 varicose veins 10.0 ELN MMP2
32 fibromuscular dysplasia 10.0
33 epilepsy 10.0
34 autosomal dominant polycystic kidney disease 10.0
35 inguinal hernia 10.0 ELN MMP2
36 marfan syndrome 10.0 ELN MMP2
37 acute proliferative glomerulonephritis 10.0 CCL2 MPO
38 proliferative glomerulonephritis 10.0 CCL2 MPO
39 glomerulonephritis 10.0 CCL2 MPO
40 kawasaki disease 10.0 CCL2 ELANE
41 ascending cholangitis 10.0 CCL2 MPO
42 crescentic glomerulonephritis 10.0 CCL2 MPO
43 systemic lupus erythematosus 10.0
44 takayasu arteritis 10.0
45 moyamoya disease 1 10.0
46 brittle bone disorder 10.0
47 hemorrhage, intracerebral 10.0
48 carotid artery occlusion 10.0
49 col1a1/2-related osteogenesis imperfecta 10.0
50 pleurisy 10.0 CCL2 MPO

Graphical network of the top 20 diseases related to Cerebral Aneurysms:



Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

MGI Mouse Phenotypes related to Cerebral Aneurysms:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.02 CCL2 CTSB ELANE MMP2 MPO

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 127)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 1 50-78-2 2244
2
Clopidogrel Approved Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
3
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
4 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Not Applicable
5 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
6 Analgesics Phase 4,Phase 3,Phase 1,Not Applicable
7 Vasodilator Agents Phase 4,Phase 1,Phase 2
8 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
9 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 1
11 Anti-Asthmatic Agents Phase 4
12 Autonomic Agents Phase 4
13 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 1
14 Antipyretics Phase 4,Phase 3,Phase 1
15 Bronchodilator Agents Phase 4
16 Respiratory System Agents Phase 4
17 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Antirheumatic Agents Phase 4,Phase 3,Phase 1
19 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 1,Not Applicable
20 Prasugrel hydrochloride Phase 4 389574-19-0
21 Purinergic P2 Receptor Antagonists Phase 4,Phase 3
22 Phosphodiesterase 3 Inhibitors Phase 4
23 Neuroprotective Agents Phase 4
24 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3
25 Phosphodiesterase Inhibitors Phase 4,Phase 2
26 Protective Agents Phase 4
27 Hematinics Phase 4,Phase 3
28 Epoetin alfa Phase 4 113427-24-0
29
Esmolol Approved Phase 3 103598-03-4, 81147-92-4 59768
30
Propofol Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 2078-54-8 4943
31
Sevoflurane Approved, Vet_approved Phase 3,Phase 2,Not Applicable 28523-86-6 5206
32
Ticagrelor Approved Phase 3 274693-27-5 9871419
33
Iron Approved, Experimental Phase 3,Phase 2 7439-89-6, 15438-31-0 27284 23925
34 Central Nervous System Depressants Phase 3,Phase 2,Phase 1,Not Applicable
35 Anesthetics Phase 3,Phase 2,Phase 1,Not Applicable
36 Pharmaceutical Solutions Phase 3,Phase 1,Phase 2
37 Adrenergic Antagonists Phase 3
38 Adrenergic beta-Antagonists Phase 3
39 Anesthetics, Inhalation Phase 3,Phase 2,Not Applicable
40 Anesthetics, Intravenous Phase 3,Phase 2,Not Applicable
41 Adrenergic beta-1 Receptor Antagonists Phase 3
42 Hypnotics and Sedatives Phase 3,Phase 2,Not Applicable
43 Anesthetics, General Phase 3,Phase 2,Not Applicable
44 Adrenergic Agents Phase 3,Not Applicable
45 Ferric Compounds Phase 3
46
Clevidipine Approved, Investigational Phase 2 167221-71-8
47
Benzocaine Approved, Investigational Phase 1, Phase 2,Not Applicable 1994-09-7, 94-09-7 2337
48
tannic acid Approved Phase 1, Phase 2,Not Applicable 1401-55-4
49
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
50
Polyestradiol phosphate Approved Phase 2 28014-46-2

Interventional clinical trials:

(show top 50) (show all 94)
# Name Status NCT ID Phase Drugs
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
2 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
3 Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm Recruiting NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
4 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
5 Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
6 Esmolol Infusion in Patients Undergoing Craniotomy Completed NCT02455440 Phase 3 Esmolol;Placebo;Propofol and sevoflurane
7 Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
8 Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failure Not yet recruiting NCT03871699 Phase 3 Ferric carboxymaltose
9 The Tilburg Vasospasm Study Terminated NCT01407614 Phase 2, Phase 3
10 Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH) Unknown status NCT02011321 Phase 2 clevidipine
11 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
12 Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
13 Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
14 Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial Recruiting NCT01895881 Phase 2 Estradiol;Placebo
15 Sevoflurane in Subarachnoidal Haemorrhage Recruiting NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
16 Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
17 Deferiprone for Ruptured Brain Aneurysm Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
18 Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage Terminated NCT02176837 Phase 2 Sodium Nitrite
19 Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm Withdrawn NCT00871065 Phase 2 Sildenafil citrate
20 Sildenafil for Prevention of Cerebral Vasospasm Withdrawn NCT01091870 Phase 2 Placebo;Sildenafil Citrate, 25 mg, 3 times a day.;Sildenafil Citrate 50 mg, 3 times a day
21 Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01878136 Phase 1, Phase 2 Tissue Plasminogen Activator
22 Aspirin Attenuates Inflammation in Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
23 Stellate Ganglion Block Using Ultrasound Guidance For Treatment Of Post Clipping Cerebral Vasospasm Completed NCT02775318 Phase 1 Bupivacaine
24 Remote Ischemic Preconditioning in Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
25 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520 Not Applicable
26 Screening Intracranial Aneurysms With Magnetic Resonance Angiography (MRA) in China Unknown status NCT00926172
27 Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity Unknown status NCT02700607 Not Applicable Intravenous Crystalloid;Intravenous HES
28 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395 Not Applicable
29 Remote Ischemic Preconditioning for Intracranial Aneurysm Treatment Unknown status NCT02162654 Not Applicable
30 Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia Unknown status NCT01460563 Not Applicable Magnesium Sulfate;0.9% saline;0.9% saline
31 Registry for Study of Coils in Intracranial Aneurysms Unknown status NCT01000675
32 Multicenter Retrospective Registry of Anterior Communicating Artery Aneurysms With Endovascular Therapy Unknown status NCT02444832
33 Contrast-free Magnetic Resonance Angiography (MRA) at 3.0 T for Intracranial Aneurysm Detection Unknown status NCT01031147
34 Long-term Clinico-radiological Evolution of Patients With Brain Lesions During Infectious Endocarditis Unknown status NCT02252900 Not Applicable
35 Chinese Small Intracranial Aneurysm Study (CSIAS) Unknown status NCT02948504
36 Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02915380
37 Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02995928 Not Applicable
38 Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Completed NCT02700126
39 Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients Completed NCT02507999 Not Applicable
40 Use of Classic LMA During Endovascular Therapy Completed NCT03288519
41 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395
42 Surgical Theater's Surgery Rehearsal Platform Completed NCT02099318 Not Applicable
43 DELTA Trial: Does Embolization With Larger Coils Lead to Better Treatment of Aneurysms Trial Completed NCT01943591 Not Applicable
44 EEG Monitoring to Assess Emergence From Neuroanesthesia Completed NCT00443807 Not Applicable
45 Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage Completed NCT00962546
46 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
47 Hypothalamo-, Pituitary-, Adrenal Axis Dysfunction in Subarachnoid Hemorrhage Completed NCT00614887
48 Risk Factors of Middle Cerebral Artery Aneurysm. Completed NCT03493035
49 Genetic Analysis of Familial Brain Aneurysms Completed NCT00011856
50 Amnesia After Surgery for Anterior Communicating Aneurysm: High Resolution Magnetic Resonance (MR) Imaging Findings Completed NCT01919775

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

42
Brain, Kidney, Heart, Testes, Eye, Pituitary, Lung

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 2467)
# Title Authors Year
1
Neoplastic Cerebral Aneurysm from Metastatic Lung Adenocarcinoma with Neuroendocrine Features. ( 30399471 )
2019
2
Relationships of Statins Therapy and Hyperlipidemia with the Incidence, Rupture, Post-repair Mortality and All-cause Mortality of Abdominal Aortic Aneurysm and Cerebral Aneurysm: A Meta-analysis and Systematic Review. ( 30688798 )
2019
3
The safety and effectiveness of the LVIS stent system for the treatment of wide-necked cerebral aneurysms: final results of the pivotal US LVIS trial. ( 30297543 )
2019
4
Deep Learning for MR Angiography: Automated Detection of Cerebral Aneurysms. ( 30351253 )
2019
5
Neutrophilic Ribonucleic Acid Expression as a Clinical Tool in Detecting Cerebral Aneurysms. ( 30395290 )
2019
6
Combined surgery and embolization to treat ruptured cerebral aneurysms with cerebral hematoma and intracranial hypertension: a retrospective analysis and review of the literature. ( 30396604 )
2019
7
Quantitative assessment of 4D hemodynamics in cerebral aneurysms using proper orthogonal decomposition. ( 30409473 )
2019
8
Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone: Preliminary Results. ( 30465954 )
2019
9
Stent-assisted coiling of cerebral aneurysms using the Y-stenting technique: a systematic review and meta-analysis. ( 30610070 )
2019
10
Persistent Primitive Hypoglossal Artery Associated With Multiple Cerebral Aneurysms. ( 30627281 )
2019
11
Cerebral aneurysms - are they associated with anatomic variations of carotid and main cerebral arteries? ( 30639500 )
2019
12
Development of a stent capable of the controlled release of basic fibroblast growth factor and argatroban to treat cerebral aneurysms: In vitro experiment and evaluation in a rabbit aneurysm model. ( 30653829 )
2019
13
Transradial approach for flow diversion treatment of cerebral aneurysms: a multicenter study. ( 30670622 )
2019
14
Quantification of hemodynamic irregularity using oscillatory velocity index in the associations with the rupture status of cerebral aneurysms. ( 30670624 )
2019
15
Delayed Treatment (≥5 Days) by Flow Diversion of Ruptured Blister-Like Cerebral Aneurysms : Case Series of 8 Consecutive Patients. ( 30683969 )
2019
16
Rupture risk of small unruptured cerebral aneurysms. ( 30684948 )
2019
17
A Phantom Menace to Medical Personnel During Endovascular Treatment of Cerebral Aneurysms: Real-Time Measurement of Radiation Exposure During Procedures. ( 30685367 )
2019
18
The effect of hospital safety-net burden on outcomes, cost, and reportable quality metrics after emergent clipping and coiling of ruptured cerebral aneurysms. ( 30797220 )
2019
19
Low-dose Prasugrel in Patients with Resistance to Clopidogrel for the Treatment of Cerebral Aneurysms: Follow-up of over 6 Months. ( 30827067 )
2019
20
Differentially expressed genes associated with the estrogen receptor pathway in cerebral aneurysms. ( 30831289 )
2019
21
How definitive treatment affects the rupture rate of unruptured cerebral aneurysms: a competing risk survival analysis. ( 30849750 )
2019
22
Editorial. Assessment of the natural history of cerebral aneurysms in the setting of competing risk. ( 30849764 )
2019
23
HoTPiG: a novel graph-based 3-D image feature set and its applications to computer-assisted detection of cerebral aneurysms and lung nodules. ( 30859456 )
2019
24
Image-Based Modeling of Blood Flow in Cerebral Aneurysms Treated with Intrasaccular Flow Diverting Devices. ( 30891958 )
2019
25
Balloon-assisted coiling of cerebral aneurysms with the dual-lumen Scepter XC balloon catheter: Experience at two high-volume centers. ( 30922198 )
2019
26
Computational fluid dynamics in cerebral aneurysms- Explaining the aneurysms shape and the timing of rupture with theoretical physics. ( 30930315 )
2019
27
Use of a First Large-Sized Coil Versus Conventional Coils for Embolization of Cerebral Aneurysms: Effects on Packing Density, Coil Length, and Durable Occlusion. ( 30946999 )
2019
28
Predicting outcomes for cerebral aneurysms treated with flow diversion: A comparison between four grading scales. ( 31004852 )
2019
29
Lower hemoglobin levels are associated with acute seizures in patients with ruptured cerebral aneurysms. ( 31009781 )
2019
30
Somatic PDGFRB Activating Variants in Fusiform Cerebral Aneurysms. ( 31031011 )
2019
31
The Natural History of Coiled Cerebral Aneurysms Stratified by Modified Raymond Roy Occlusion Classification. ( 31042602 )
2019
32
Subtraction CT angiography in the follow-up of treated cerebral aneurysms. ( 31044261 )
2019
33
Long-term Outcomes of Cerebral Aneurysms in Children. ( 31068385 )
2019
34
Multiple Cerebral Aneurysms Associated With Neurofibromatosis Type 1. ( 31080139 )
2019
35
Secondary coiling after incomplete surgical clipping of cerebral aneurysms: a rescue strategy or a treatment option for complex cases? Institutional series and systematic review. ( 29417290 )
2019
36
Flow Diversion of Posterior Circulation Cerebral Aneurysms: A Single-Institution Series of 59 Cases. ( 29608702 )
2019
37
Pharmacy-Mediated Antiplatelet Management Protocol Compared to One-time Platelet Function Testing Prior to Pipeline Embolization of Cerebral Aneurysms: A Propensity Score-Matched Cohort Study. ( 29608747 )
2019
38
Intraoperative Assessment of Cortical Perfusion After Intracranial-To-Intracranial and Extracranial-To-Intracranial Bypass for Complex Cerebral Aneurysms Using Flow 800. ( 29897545 )
2019
39
The Successful Use of Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and a Pituitary Lesion. ( 29952859 )
2019
40
Long-term retreatment rates of cerebral aneurysms in a population-level cohort. ( 30185600 )
2019
41
Variational data assimilation for transient blood flow simulations: Cerebral aneurysms as an illustrative example. ( 30198152 )
2019
42
Antiplatelet therapy and the risk of ischemic and hemorrhagic complications associated with Pipeline embolization of cerebral aneurysms: a systematic review and pooled analysis. ( 30201813 )
2019
43
Clear Detection of Thin-Walled Regions in Unruptured Cerebral Aneurysms by Using Computational Fluid Dynamics. ( 30253995 )
2019
44
Residual Cerebral Aneurysms After Microsurgical Clipping: A New Scale, an Agreement Study, and a Systematic Review of the Literature. ( 30261387 )
2019
45
Giant cerebral aneurysm in a patient with Cowden syndrome treated with surgical clipping; a case report. ( 30904793 )
2019
46
A case of posterior reversible encephalopathy syndrome after surgical clipping of unruptured cerebral aneurysm. ( 30660882 )
2019
47
Hepatitis B virus infected patients show increased risk of cerebral aneurysm rupture: A retrospective analysis. ( 30850179 )
2019
48
MRI Screening for Cerebral Aneurysm in Adult Polycystic Kidney Disease: Is the Money Worth Spending? ( 30801234 )
2019
49
Rupture of Thrombosed Cerebral Aneurysm During Antithrombotic Therapy for Ischemic Stroke: Case Report and Literature Review. ( 30898732 )
2019
50
Contrast Media-Induced Nephropathy in Patients with Unruptured Cerebral Aneurysm After Coiling Endovascular Treatment. ( 30196168 )
2019

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

Pathways related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.17 CCL2 MMP2 MPO
2
Show member pathways
12.11 CTSB ELANE ELN MMP2
3
Show member pathways
11.79 CCL2 ELN MMP2
4 11.6 CCL2 MMP2
5 11.54 CCL2 MMP2
6
Show member pathways
11.52 ELANE MMP2
7 11.44 CCL2 MMP2
8 11.37 ELANE MPO
9 11.02 ELANE ELN
10 10.94 CCL2 MMP2
11 10.93 CCL2 ELN MMP2
12 10.87 CCL2 MMP2
13 10.68 CTSB MMP2
14 10.48 ELANE MMP2 MPO
15 10.46 CCL2 MPO

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 CCL2 CTSB ELANE MMP2 MPO
2 extracellular region GO:0005576 9.43 CCL2 CTSB ELANE ELN MMP2 MPO
3 secretory granule GO:0030141 9.32 ELANE MPO
4 azurophil granule lumen GO:0035578 9.26 ELANE MPO
5 collagen-containing extracellular matrix GO:0062023 8.92 CTSB ELANE ELN MMP2

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.54 CTSB ELANE MPO
2 animal organ morphogenesis GO:0009887 9.4 CCL2 ELN
3 extracellular matrix disassembly GO:0022617 9.32 ELANE MMP2
4 collagen catabolic process GO:0030574 9.26 CTSB MMP2
5 defense response to fungus GO:0050832 9.16 ELANE MPO
6 negative regulation of growth of symbiont in host GO:0044130 8.96 ELANE MPO
7 response to yeast GO:0001878 8.62 ELANE MPO

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.13 CTSB ELANE MMP2
2 serine-type endopeptidase activity GO:0004252 8.62 ELANE MMP2

Sources for Cerebral Aneurysms

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
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75 UMLS via Orphanet
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