MCID: CRB086
MIFTS: 40

Cerebral Aneurysms

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 53
Cerebral Aneurysm 54 71
Cerebral Arterial Aneurysm 71

Classifications:



External Ids:

UMLS 71 C0917996 C1290398

Summaries for Cerebral Aneurysms

NINDS : 53 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and vascular disease. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Degradation of the extracellular matrix and AGE-RAGE signaling pathway in diabetic complications. The drugs Cilostazol and Iron have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and heart, and related phenotype is neoplasm.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 416)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 32.2 MMP2 ELN CCL2
2 vascular disease 30.1 ELN CST3 CCL2
3 arteriosclerosis 29.8 ELN CST3 CCL2
4 peripheral artery disease 29.6 CST3 CCL2
5 homocysteinemia 29.5 ELN CST3 CCL2
6 proteasome-associated autoinflammatory syndrome 1 29.5 ELANE CCL2
7 lung disease 29.1 ELN ELANE CCL2
8 aortic disease 29.0 MMP2 ELN
9 varicose veins 28.8 MMP2 ELN CCL2
10 myocardial infarction 28.6 MMP2 ELN CST3 CCL2
11 aortic aneurysm, familial abdominal, 1 28.2 MMP2 ELN ELANE CST3 CCL2
12 aneurysm 12.1
13 intracranial berry aneurysm 12.0
14 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.4
15 loeys-dietz syndrome 4 11.3
16 rare surgical neurologic disease 10.6
17 hydrocephalus 10.5
18 arteriovenous malformation 10.5
19 familial cerebral saccular aneurysm 10.5
20 ocular motor apraxia 10.4
21 headache 10.4
22 endocarditis 10.4
23 cardiac arrest 10.3
24 kidney disease 10.3
25 polycystic kidney disease 10.3
26 cerebrovascular disease 10.3
27 aphasia 10.3
28 renal hypertension 10.2
29 infective endocarditis 10.2
30 pica disease 10.2
31 head injury 10.2
32 fibromuscular dysplasia 10.2
33 autosomal dominant polycystic kidney disease 10.2
34 arteriovenous malformations of the brain 10.2
35 moyamoya disease 1 10.2
36 hydrops, lactic acidosis, and sideroblastic anemia 10.2
37 thrombosis 10.2
38 transient cerebral ischemia 10.2
39 aortic aneurysm 10.2
40 seizure disorder 10.2
41 coarctation of aorta 10.1
42 neurofibromatosis, type iv, of riccardi 10.1
43 visual epilepsy 10.1
44 brain edema 10.1
45 carotid artery occlusion 10.1
46 vasculitis 10.1
47 48,xyyy 10.1
48 ptosis 10.1
49 carotid stenosis 10.1
50 pituitary adenoma 10.1

Graphical network of the top 20 diseases related to Cerebral Aneurysms:



Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

MGI Mouse Phenotypes related to Cerebral Aneurysms:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CST3 CTSB ELANE MMP2

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 136)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
2
Iron Approved, Experimental Phase 4 7439-89-6, 15438-31-0 23925 27284
3
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
4
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
5
Tenecteplase Approved Phase 4 191588-94-0
6 Anti-Asthmatic Agents Phase 4
7 Respiratory System Agents Phase 4
8 Autonomic Agents Phase 4
9 Protective Agents Phase 4
10 Neuroprotective Agents Phase 4
11 Prasugrel hydrochloride Phase 4 389574-19-0
12 Bronchodilator Agents Phase 4
13 Phosphodiesterase 3 Inhibitors Phase 4
14 Pharmaceutical Solutions Phase 4
15 Ferric Compounds Phase 4
16 Neurotransmitter Agents Phase 4
17 Fibrinolytic Agents Phase 4
18 Platelet Aggregation Inhibitors Phase 4
19 Purinergic P2Y Receptor Antagonists Phase 4
20 calcium heparin Phase 4
21 Hematinics Phase 4
22 Epoetin alfa Phase 4 113427-24-0
23
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
24
Ticagrelor Approved Phase 3 274693-27-5 9871419
25
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
26 Anesthetics Phase 3
27 Tin Fluorides Phase 3
28 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2, Phase 3
29 Hypolipidemic Agents Phase 2, Phase 3
30 Anticholesteremic Agents Phase 2, Phase 3
31 Lipid Regulating Agents Phase 2, Phase 3
32 Antimetabolites Phase 2, Phase 3
33 Anti-Inflammatory Agents Phase 3
34 Anti-Inflammatory Agents, Non-Steroidal Phase 3
35 Analgesics, Non-Narcotic Phase 3
36 Antipyretics Phase 3
37 Cyclooxygenase Inhibitors Phase 3
38 Antirheumatic Agents Phase 3
39 Analgesics Phase 3
40 Astragalus Phase 2, Phase 3
41 Salicylates Phase 3
42 Vasoconstrictor Agents Phase 3
43
Nimodipine Approved, Investigational Phase 1, Phase 2 66085-59-4 4497
44
Polyestradiol phosphate Approved Phase 2 28014-46-2
45
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
46
Propofol Approved, Investigational, Vet_approved Phase 2 2078-54-8 4943
47
Sevoflurane Approved, Vet_approved Phase 2 28523-86-6 5206
48
Midazolam Approved, Illicit Phase 2 59467-70-8 4192
49
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
50
Everolimus Approved Phase 2 159351-69-6 6442177 70789204

Interventional clinical trials:

(show top 50) (show all 107)
# Name Status NCT ID Phase Drugs
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
2 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function in Patients Undergoing Intracranial Aneurysm Surgery. Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
3 Comparison of Dual-Antiplatelet and Triple-Antiplatelet Preparation Using P2Y12 Assay in Patients With High On-Treatment Platelet Reactivity Undergoing Stent-Assisted Coil Embolization for An Unruptured Intracranial Aneurysm Recruiting NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
4 The Effect of Ferric Carboximaltose on Intra-myocardial Iron Load Assessed by Cardiac Magnetic Resonance in Patients With Heart Failure With Reduced Ejection Fraction (HFREF). Not yet recruiting NCT03871699 Phase 4 Ferric carboxymaltose
5 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
6 A Double Blinded, Placebo Controlled, Pilot Study to Evaluate the Safety of Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
7 TRIANA: A Randomized Trial to Compare the Efficay and Safety of Thrombolysis With Primary Angioplasty as Initial Reperfusion Therapy in Older Patients (>= 75 Years Old) With Acute Myocardial Infarction Terminated NCT00257309 Phase 4 Tenecteplase + UFH (+ clopidogrel, since 01/97)
8 EARLYdrain - Prospective Outcome Study of Early Lumbar Drainage in Aneurysmal Subarachnoid Hemorrhage Completed NCT01258257 Phase 3
9 High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage: Is it Better? Completed NCT01077206 Phase 2, Phase 3 Simvastatin
10 Ticagrelor Versus Clopidogrel for Platelet Inhibition in Patients Undergoing Neurovascular Stenting for Intracranial Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
11 Utility of Lung Clearance Index Score as a Noninvasive Marker of Small Airways Disease Recruiting NCT03241420 Phase 3
12 Efficacy Study of Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT03271697 Phase 2, Phase 3 Astragalus Membranaceus;Placebo
13 Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain Aneurysms(EVOLVE): A Phase 3 Multicenter Randomized Study Not yet recruiting NCT04192955 Phase 3 Acetyl Salicylate
14 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
15 Hypertonic Saline Solution in Aneurysmal Subarachnoid Hemorrhage: A Randomized - Phase II Single Blinded Clinical Trial Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
16 Safety and Pharmacokinetic Evaluation of Sodium Nitrite Injection for the Prevention of Post-Subarachnoid Hemorrhage Induced Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
17 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
18 Estrogen Therapy as Prevention in the Progression of Aneurysm Recruiting NCT01895881 Phase 2 Estradiol;Placebo
19 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
20 Short Term Application of Sevoflurane in Patients With Subarachnoid Haemorrhage: a Feasibility and Safety Study Recruiting NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
21 Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms Not yet recruiting NCT04141020 Phase 2 Sirolimus
22 Deferiprone Trial for Subarachnoid Hemorrhage (SAH) Patients Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
23 Evaluation of Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage From a Cerebral Aneurysm Terminated NCT02176837 Phase 2 Sodium Nitrite
24 Safety and Efficacy Trial of Sildenafil Citrate in Attenuation of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT00871065 Phase 2 Sildenafil citrate
25 The Effect of Autologous Adipose Mesenchymal Stem Cells in Treatment of Airway Injury in Patients Exposed to Sulfur Mustard Unknown status NCT02749448 Phase 1
26 Aspirin as a Promising Agent to Attenuate Inflammation in the Wall of Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
27 Efficacy Of Ultrasound Guided Stellate Ganglion Block To Relieve Vasospasm Following Clipping Of Cerebral Aneurysm Completed NCT02775318 Phase 1 Bupivacaine
28 Prophylactic Remote Ischemic Preconditioning for Cerebral Vasospasm Following Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
29 Phase I Safety, Blood Brain Barrier Permeability and Potential Efficacy of Etanercept for Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT01865630 Phase 1 Etanercept
30 Safety of Rapid Ventricular Pacing During Cerebral Aneurysm Surgery by Multimodal Neuromonitoring Unknown status NCT03185091
31 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520
32 Epidemiology of Cerebral Aneurysms With MRA in China in Middle-aged or Elder Person: a Population-based Survey Unknown status NCT00926172
33 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395
34 Effects of Valproic Acid and Magnesium Sulphate on Rocuronium Requirement and Postoperative Analgesia in Patients Undergoing Craniotomy for Cerebrovascular Surgery Unknown status NCT01460563 Magnesium Sulfate;0.9% saline;0.9% saline
35 Predictive Values of Serum Adiponectin Levels in Aneurysmal Subarachnoid Hemorrhage. Unknown status NCT02814162
36 To Investigate the Coexistence of Atherosclerotic Intracranial Arterial Stenosis With Intracranial Aneurysms Unknown status NCT02795078 conservative treatment
37 The Neuroprotection of Sevoflurane Preconditioning on Perioperative Ischemia-reperfusion Injury During Intracranial Aneurysm Surgery Unknown status NCT01204268
38 The Role of Remote Ischemic Preconditioning in the Prevention of Ischemic Brain Damage During Intracranial Aneurysm Treatment (RIPAT) - A Prospective Randomized Exploratory Study Unknown status NCT02162654
39 Detection of Intracranial Aneurysm With Non-enhanced, Three-dimensional Time-of-flight Magnetic Resonance Angiography(3D−TOF−MRA): a Prospective Comparison With Three-dimensional Reconstructed Digital Subtraction Angiography (3D RDSA) Unknown status NCT01031147
40 Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02995928
41 Linkage Analysis of Familial Intracranial Aneurysms Completed NCT00011856
42 Barrow Ruptured Aneurysm Study Completed NCT01593267
43 The Use of the Classic Laryngeal Mask Airway in Patients With Cerebral Aneurysm Undergoing Endovascular Therapy Completed NCT03288519
44 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
45 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395
46 Assessment of Cerebral Circulation and Perfusion in Adults After Neonatal Carotid Occlusion Completed NCT00646672
47 Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients - A Prospective, Blinded Randomized Controlled Trial Completed NCT02507999
48 A Case-control Study of Independent Predictors of Middle Cerebral Artery Aneurysm. Completed NCT03493035
49 Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Completed NCT02700126
50 A Comparison of the EEGo and BIS Monitors to Assess Emergence From Neuroanesthesia Completed NCT00443807

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

40
Brain, Kidney, Heart, Testes, Pituitary, Endothelial, Eye

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 5959)
# Title Authors PMID Year
1
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm. 54 61
17714769 2007
2
Management of polycystic liver disease. 54 61
15701294 2005
3
[In situ localization of mRNA gelatinases in cerebral aneurysms]. 54 61
11715488 1999
4
Morphometric analysis of reticular and elastin fibers in the cerebral arteries of patients with intracranial aneurysms. 54 61
2362672 1990
5
Olfactory dysfunction in patients undergoing supraorbital keyhole craniotomy for clipping of unruptured aneurysms. 61
31769083 2020
6
The Pipeline Embolization Device: Changes in Practice and Reduction of Complications in the Treatment of Anterior Circulation Aneurysms in a Multicenter Cohort. 61
30860254 2020
7
Volumes, outcomes, and complications after surgical versus endovascular treatment of aneurysms in the United States (1993-2015): continued evolution versus steady-state after more than 2 decades of practice. 61
32032946 2020
8
Two- to five-year follow-up of 78 patients after treatment with the Flow Redirection Endoluminal Device. 61
31594435 2020
9
Morphological and Hemodynamic Risk Factors for Middle Cerebral Artery Aneurysm: a Case-Control Study of 190 Patients. 61
32029748 2020
10
The RISE trial: A Randomized Trial on Intra-Saccular Endobridge devices. 61
31690151 2020
11
Tensor-cut: A tensor-based graph-cut blood vessel segmentation method and its application to renal artery segmentation. 61
31884249 2020
12
Incorporating variability of patient inflow conditions into statistical models for aneurysm rupture assessment. 61
32008209 2020
13
Induction of large cerebral aneurysms by intraperitoneal administration of β-aminopropionitrile fumarate in male rats. 61
32031355 2020
14
Evaluation of a Desktop 3D Printed Rigid Refractive-Indexed-Matched Flow Phantom for PIV Measurements on Cerebral Aneurysms. 61
31820351 2020
15
Cerebral arterial infundibula are preaneurysmal lesions caused by direct flow impact. 61
31954894 2020
16
Propensity Score Matching Analysis for the Patients of Unruptured Cerebral Aneurysm from a Post Hoc Analysis of a Nationwide Database in Japan. 61
31931237 2020
17
[The Analysis of the Thickness of a Cerebral Aneurysm:Can Predict the Translucent-type of Unruptured Middle Cerebral Artery Aneurysm Preoperatively?] 61
31983684 2020
18
Diagnostic value of non-enhanced computed tomography in identifying location of ruptured cerebral aneurysm in patients with aneurysmal subarachnoid haemorrhage. 61
31967317 2020
19
Metal artifact reduction algorithm for image quality improvement of cone-beam CT images of medium or large cerebral aneurysms treated with stent-assisted coil embolization. 61
31701181 2020
20
TREATMENT OF INTERNAL CAROTID ANEURYSMS USING PIPELINE EMBOLIZATION DEVICES: MEASURING THE RADIATION DOSE OF THE PATIENT AND DETERMINING THE FACTORS AFFECTING IT. 61
31922569 2020
21
Clinical Safety and Effectiveness of Stent-Assisted Coil Embolization with Neuroform Atlas Stent in Intracranial Aneurysm. 61
31805757 2020
22
Tenascin-C in brain injuries and edema after subarachnoid hemorrhage: Findings from basic and clinical studies. 61
30242870 2020
23
Trans-lamina terminalis approach assisted by endovascular temporary basilar artery occlusion for high-positioned, recurrent, basilar tip aneurysm: A technical case report. 61
32038885 2020
24
Flow Diversion for Intracranial Aneurysm Treatment: Trials Involving Flow Diverters and Long-Term Outcomes. 61
31838533 2020
25
[Intracranial Pseudoaneurysm Arising after Radiotherapy for Oligodendroglioma:A Case Report]. 61
31983685 2020
26
Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models. 61
31904232 2020
27
Coil Embolization for a Cerebral Aneurysm in a Heart Transplantation Patient: A Case Report. 61
31938680 2020
28
Comparison of statistical learning approaches for cerebral aneurysm rupture assessment. 61
31485987 2020
29
Correction to: Cerebral aneurysm in a giant perivascular space. 61
31907564 2020
30
Cell Culture Model to Study Cerebral Aneurysm Biology. 61
31407059 2020
31
A reduced-order model of a patient-specific cerebral aneurysm for rapid evaluation and treatment planning. 61
32037019 2020
32
Expanding Indications for Flow Diverters: Ruptured Aneurysms, Blister Aneurysms, and Dissecting Aneurysms. 61
31838529 2020
33
Safety and efficacy of endovascular treatment of ruptured tiny cerebral aneurysms compared with ruptured larger aneurysms. 61
31930939 2020
34
Delayed Leukoencephalopathy: A Rare Complication after Coiling of Cerebral Aneurysms. 61
32001447 2020
35
Treatment and diagnosis of cerebral aneurysms in the post-International Subarachnoid Aneurysm Trial (ISAT) era: trends and outcomes. 61
31959634 2020
36
Correlation between multiple cerebral aneurysms and a rare type of segmental duplication of the middle cerebral artery. 61
31901227 2020
37
Factors related to adverse events during endovascular coil embolization for ruptured cerebral aneurysms. 61
31980542 2020
38
Size-Dependent Distribution of Patient-Specific Hemodynamic Factors in Unruptured Cerebral Aneurysms Using Computational Fluid Dynamics. 61
31991621 2020
39
Factors affecting recurrence and management of recurrent cerebral aneurysms after initial coiling. 61
31992106 2020
40
Traumatic iatrogenic dissecting anterior cerebral artery aneurysms: conservative management as a therapeutic option. 61
31983243 2020
41
Platelet Dynamics and Hemodynamics of Cerebral Aneurysms Treated with Flow-Diverting Stents. 61
31549329 2020
42
Use of Preprocedural, Multiple Antiplatelet Medications for Coil Embolization of Ruptured Cerebral Aneurysm in the Acute Stage Improved Clinical Outcome and Reduced Thromboembolic Complications without Hemorrhagic Complications. 61
31604135 2020
43
Spontaneous Thrombosis of Giant Dissecting Fusiform Middle Cerebral Aneurysm After Double-Barrel Superficial Temporal Artery-Middle Cerebral Artery Bypass: A Case Report of Decision-Making in a Limited Resource Environment. 61
31954890 2020
44
Seeing beyond the gut: An unusual cause of massive hematemesis. 61
31929311 2020
45
Thromboelastometry as a Comprehensive Assessment of Hypercoagulation After Aneurysmal Subarachnoid Hemorrhage: A Case Report and Literature Review. 61
31407079 2020
46
Toll-Like Receptor 4 and Tenascin-C Signaling in Cerebral Vasospasm and Brain Injuries After Subarachnoid Hemorrhage. 61
31407069 2020
47
HoTPiG: a novel graph-based 3-D image feature set and its applications to computer-assisted detection of cerebral aneurysms and lung nodules. 61
30859456 2019
48
256-row multislice CT angiography in the postoperative evaluation of cerebral aneurysms treated with titanium clips: using three-dimensional rotational angiography as the standard of reference. 61
31844961 2019
49
Cerebral aneurysms treated with low-profile visualized intraluminal support device (LVIS Jr) Y-stent constructs: Technical experience with a single microcatheter technique. 61
31852417 2019
50
Flow diversion beyond the circle of Willis: endovascular aneurysm treatment in peripheral cerebral arteries employing a novel low-profile flow diverting stent. 61
31088939 2019

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 MMP2 ELANE CTSB CST3 CCL2
2 extracellular region GO:0005576 9.43 MMP2 ELN ELANE CTSB CST3 CCL2
3 collagen-containing extracellular matrix GO:0062023 8.92 MMP2 ELN ELANE CTSB

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.43 ELANE CTSB CST3
2 extracellular matrix disassembly GO:0022617 9.16 MMP2 ELANE
3 positive regulation of smooth muscle cell proliferation GO:0048661 8.96 MMP2 ELANE
4 collagen catabolic process GO:0030574 8.62 MMP2 CTSB

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.16 ELANE CST3
2 peptidase activity GO:0008233 9.13 MMP2 ELANE CTSB
3 endopeptidase activity GO:0004175 8.62 ELANE CTSB

Sources for Cerebral Aneurysms

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....