MCID: CRB086
MIFTS: 41

Cerebral Aneurysms

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 54
Cerebral Aneurysm 55 72
Cerebral Arterial Aneurysm 72

Classifications:



External Ids:

UMLS 72 C0917996 C1290398

Summaries for Cerebral Aneurysms

NINDS : 54 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and vasculitis. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Innate Immune System and Degradation of the extracellular matrix. The drugs Aspirin and Cilostazol have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and testes, and related phenotype is neoplasm.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 399)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 32.6 MMP2 ELN
2 vasculitis 30.2 ELANE CCL2
3 arteriosclerosis 30.1 ELN CCL2
4 autosomal dominant polycystic kidney disease 29.9 CST3 CCL2
5 peripheral artery disease 29.8 CST3 CCL2
6 proteasome-associated autoinflammatory syndrome 1 29.7 ELANE CCL2
7 bacterial infectious disease 29.7 ELANE CCL2
8 vascular disease 29.5 ELN ELANE CST3 CCL2
9 aortic disease 29.3 MMP2 ELN
10 varicose veins 29.3 MMP2 ELN
11 lung disease 29.2 ELN ELANE CCL2
12 myocardial infarction 28.4 MMP2 CST3 CCL2
13 aortic aneurysm, familial abdominal, 1 27.9 MMP2 ELN ELANE CST3 CCL2
14 aneurysm 12.1
15 intracranial berry aneurysm 12.0
16 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.4
17 loeys-dietz syndrome 4 11.3
18 rare surgical neurologic disease 10.6
19 hydrocephalus 10.5
20 congenital hydrocephalus 10.5
21 arteriovenous malformation 10.5
22 familial cerebral saccular aneurysm 10.5
23 ocular motor apraxia 10.4
24 headache 10.4
25 endocarditis 10.4
26 cardiac arrest 10.3
27 kidney disease 10.3
28 polycystic kidney disease 10.3
29 aortic coarctation 10.3
30 cerebrovascular disease 10.3
31 aphasia 10.3
32 renal hypertension 10.2
33 infective endocarditis 10.2
34 mid-dermal elastolysis 10.2 ELN ELANE
35 pica disease 10.2
36 head injury 10.2
37 elephantiasis 10.2 ELN ELANE
38 chorioamnionitis 10.2 ELANE CCL2
39 erysipelas 10.2 ELN ELANE
40 alpha-1-antitrypsin deficiency 10.2 ELN ELANE
41 fibromuscular dysplasia 10.2
42 thrombosis 10.2
43 idiopathic interstitial pneumonia 10.2 ELANE CCL2
44 pulmonary emphysema 10.2 ELN ELANE
45 adult respiratory distress syndrome 10.2 ELN ELANE
46 pneumonia 10.2 ELANE CCL2
47 arteriovenous malformations of the brain 10.2
48 moyamoya disease 1 10.2
49 hydrops, lactic acidosis, and sideroblastic anemia 10.2
50 transient cerebral ischemia 10.2

Graphical network of the top 20 diseases related to Cerebral Aneurysms:



Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

MGI Mouse Phenotypes related to Cerebral Aneurysms:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CST3 CTSB ELANE MMP2

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 137)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
2
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
3
Iron Approved, Experimental Phase 4 15438-31-0, 7439-89-6 23925 27284
4
Clopidogrel Approved Phase 4 113665-84-2, 120202-66-6 60606
5
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
6
Tenecteplase Approved Phase 4 191588-94-0
7 Cyclooxygenase Inhibitors Phase 4
8 Antipyretics Phase 4
9 Respiratory System Agents Phase 4
10 Neuroprotective Agents Phase 4
11 Protective Agents Phase 4
12 Anti-Asthmatic Agents Phase 4
13 Prasugrel hydrochloride Phase 4 389574-19-0
14 Autonomic Agents Phase 4
15 Phosphodiesterase 3 Inhibitors Phase 4
16 Bronchodilator Agents Phase 4
17 Pharmaceutical Solutions Phase 4
18 Ferric Compounds Phase 4
19 Neurotransmitter Agents Phase 4
20 Fibrinolytic Agents Phase 4
21 Purinergic P2Y Receptor Antagonists Phase 4
22 Purinergic P2 Receptor Antagonists Phase 4
23 Platelet Aggregation Inhibitors Phase 4
24 calcium heparin Phase 4
25 Hematinics Phase 4
26 Epoetin alfa Phase 4 113427-24-0
27
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
28
Ticagrelor Approved Phase 3 274693-27-5 9871419
29 Tin Fluorides Phase 3
30 Anesthetics Phase 3
31 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2, Phase 3
32 Lipid Regulating Agents Phase 2, Phase 3
33 Hypolipidemic Agents Phase 2, Phase 3
34 Anticholesteremic Agents Phase 2, Phase 3
35 Antimetabolites Phase 2, Phase 3
36 Astragalus Phase 2, Phase 3
37 Vasoconstrictor Agents Phase 3
38
Nimodipine Approved, Investigational Phase 1, Phase 2 66085-59-4 4497
39
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
40
Polyestradiol phosphate Approved Phase 2 28014-46-2
41
Propofol Approved, Investigational, Vet_approved Phase 2 2078-54-8 4943
42
Sevoflurane Approved, Vet_approved Phase 2 28523-86-6 5206
43
Midazolam Approved, Illicit Phase 2 59467-70-8 4192
44
Deferiprone Approved Phase 2 30652-11-0 2972
45
Imidacloprid Vet_approved Phase 2 105827-78-9 86418
46 calcium channel blockers Phase 1, Phase 2
47 Antihypertensive Agents Phase 1, Phase 2
48 Estrogens Phase 2
49 Contraceptive Agents Phase 2
50 Estradiol 17 beta-cypionate Phase 2

Interventional clinical trials:

(show top 50) (show all 104)
# Name Status NCT ID Phase Drugs
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
2 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function in Patients Undergoing Intracranial Aneurysm Surgery. Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
3 Comparison of Dual-Antiplatelet and Triple-Antiplatelet Preparation Using P2Y12 Assay in Patients With High On-Treatment Platelet Reactivity Undergoing Stent-Assisted Coil Embolization for An Unruptured Intracranial Aneurysm Recruiting NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
4 The Effect of Ferric Carboximaltose on Intra-myocardial Iron Load Assessed by Cardiac Magnetic Resonance in Patients With Heart Failure With Reduced Ejection Fraction (HFREF). Not yet recruiting NCT03871699 Phase 4 Ferric carboxymaltose
5 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
6 A Double Blinded, Placebo Controlled, Pilot Study to Evaluate the Safety of Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
7 TRIANA: A Randomized Trial to Compare the Efficay and Safety of Thrombolysis With Primary Angioplasty as Initial Reperfusion Therapy in Older Patients (>= 75 Years Old) With Acute Myocardial Infarction Terminated NCT00257309 Phase 4 Tenecteplase + UFH (+ clopidogrel, since 01/97)
8 EARLYdrain - Prospective Outcome Study of Early Lumbar Drainage in Aneurysmal Subarachnoid Hemorrhage Completed NCT01258257 Phase 3
9 High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage: Is it Better? Completed NCT01077206 Phase 2, Phase 3 Simvastatin
10 Ticagrelor Versus Clopidogrel for Platelet Inhibition in Patients Undergoing Neurovascular Stenting for Intracranial Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
11 Utility of Lung Clearance Index Score as a Noninvasive Marker of Small Airways Disease Recruiting NCT03241420 Phase 3
12 Efficacy Study of Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT03271697 Phase 2, Phase 3 Astragalus Membranaceus;Placebo
13 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
14 Hypertonic Saline Solution in Aneurysmal Subarachnoid Hemorrhage: A Randomized - Phase II Single Blinded Clinical Trial Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
15 Safety and Pharmacokinetic Evaluation of Sodium Nitrite Injection for the Prevention of Post-Subarachnoid Hemorrhage Induced Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
16 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
17 Estrogen Therapy as Prevention in the Progression of Aneurysm Recruiting NCT01895881 Phase 2 Estradiol;Placebo
18 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
19 Short Term Application of Sevoflurane in Patients With Subarachnoid Haemorrhage: a Feasibility and Safety Study Recruiting NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
20 Deferiprone Trial for Subarachnoid Hemorrhage (SAH) Patients Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
21 Evaluation of Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage From a Cerebral Aneurysm Terminated NCT02176837 Phase 2 Sodium Nitrite
22 Safety and Efficacy Trial of Sildenafil Citrate in Attenuation of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT00871065 Phase 2 Sildenafil citrate
23 The Effect of Autologous Adipose Mesenchymal Stem Cells in Treatment of Airway Injury in Patients Exposed to Sulfur Mustard Unknown status NCT02749448 Phase 1
24 Aspirin as a Promising Agent to Attenuate Inflammation in the Wall of Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
25 Efficacy Of Ultrasound Guided Stellate Ganglion Block To Relieve Vasospasm Following Clipping Of Cerebral Aneurysm Completed NCT02775318 Phase 1 Bupivacaine
26 Prophylactic Remote Ischemic Preconditioning for Cerebral Vasospasm Following Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
27 Phase I Safety, Blood Brain Barrier Permeability and Potential Efficacy of Etanercept for Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT01865630 Phase 1 Etanercept
28 Safety of Rapid Ventricular Pacing During Cerebral Aneurysm Surgery by Multimodal Neuromonitoring Unknown status NCT03185091
29 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520
30 Epidemiology of Cerebral Aneurysms With MRA in China in Middle-aged or Elder Person: a Population-based Survey Unknown status NCT00926172
31 Barrow Ruptured Aneurysm Study Unknown status NCT01593267
32 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395
33 Effects of Valproic Acid and Magnesium Sulphate on Rocuronium Requirement and Postoperative Analgesia in Patients Undergoing Craniotomy for Cerebrovascular Surgery Unknown status NCT01460563 Magnesium Sulfate;0.9% saline;0.9% saline
34 Predictive Values of Serum Adiponectin Levels in Aneurysmal Subarachnoid Hemorrhage. Unknown status NCT02814162
35 The Neuroprotection of Sevoflurane Preconditioning on Perioperative Ischemia-reperfusion Injury During Intracranial Aneurysm Surgery Unknown status NCT01204268
36 The Role of Remote Ischemic Preconditioning in the Prevention of Ischemic Brain Damage During Intracranial Aneurysm Treatment (RIPAT) - A Prospective Randomized Exploratory Study Unknown status NCT02162654
37 Detection of Intracranial Aneurysm With Non-enhanced, Three-dimensional Time-of-flight Magnetic Resonance Angiography(3D−TOF−MRA): a Prospective Comparison With Three-dimensional Reconstructed Digital Subtraction Angiography (3D RDSA) Unknown status NCT01031147
38 Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02995928
39 Linkage Analysis of Familial Intracranial Aneurysms Completed NCT00011856
40 The Use of the Classic Laryngeal Mask Airway in Patients With Cerebral Aneurysm Undergoing Endovascular Therapy Completed NCT03288519
41 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
42 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395
43 Assessment of Cerebral Circulation and Perfusion in Adults After Neonatal Carotid Occlusion Completed NCT00646672
44 Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients - A Prospective, Blinded Randomized Controlled Trial Completed NCT02507999
45 A Case-control Study of Independent Predictors of Middle Cerebral Artery Aneurysm. Completed NCT03493035
46 Impact of Genetic Polymorphism on Propofol Requirement and Recovery for Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population Completed NCT02700126
47 A Comparison of the EEGo and BIS Monitors to Assess Emergence From Neuroanesthesia Completed NCT00443807
48 A Feasibility Study to Evaluate the Safety and Effectiveness of Implantation of 'Flowise Cerebral Flow Diverter' for the Treatment of Unruptured Wide-necked Cerebral Aneurysm in the Internal Carotid Artery Completed NCT02609867
49 Computed Tomographic Perfusion and Computed Tomographic Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage Completed NCT00962546
50 Impact of Intravascular Fluid Resuscitation on Whole Blood Viscosity During Coiling Embolization Procedure for Cerebral Artery Aneurysm Completed NCT02700607 Intravenous Crystalloid;Intravenous HES

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

41
Brain, Kidney, Testes, Endothelial, Eye, Heart, Pituitary

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 5827)
# Title Authors PMID Year
1
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm. 9 38
17714769 2007
2
Management of polycystic liver disease. 9 38
15701294 2005
3
[In situ localization of mRNA gelatinases in cerebral aneurysms]. 9 38
11715488 1999
4
Morphometric analysis of reticular and elastin fibers in the cerebral arteries of patients with intracranial aneurysms. 9 38
2362672 1990
5
Thromboelastometry as a Comprehensive Assessment of Hypercoagulation After Aneurysmal Subarachnoid Hemorrhage: A Case Report and Literature Review. 38
31407079 2020
6
Toll-Like Receptor 4 and Tenascin-C Signaling in Cerebral Vasospasm and Brain Injuries After Subarachnoid Hemorrhage. 38
31407069 2020
7
Cell Culture Model to Study Cerebral Aneurysm Biology. 38
31407059 2020
8
Anterior Cerebral Artery Dissection in a Patient With Autosomal Dominant Polycystic Kidney Disease. 38
31296478 2019
9
A3-A3 Bypass Surgery for Aneurysm: Technical Nuances. 38
30576562 2019
10
Histological analysis of infiltrating macrophages in the cerebral aneurysm walls. 38
31227407 2019
11
Assessment of ischemic risk following intracranial-to-intracranial and extracranial-to-intracranial bypass for complex aneurysms using intraoperative Indocyanine Green-based flow analysis. 38
31266716 2019
12
The re-anastomosis end-to-end bypass technique: a comprehensive review of the technical characteristics and surgical experience. 38
30255374 2019
13
Diagnostic accuracy of somatosensory evoked potentials during intracranial aneurysm clipping for perioperative stroke. 38
31399827 2019
14
Delayed development of a de novo contralateral middle cerebral artery aneurysm in a patient with hyperimmunoglobulin E syndrome: A case report. 38
30803337 2019
15
A Case of Burning Throat Pain. 38
31378444 2019
16
Comparative analysis of coil embolization in posterior and anterior communicating artery aneurysms. 38
30655359 2019
17
Transradial approach for flow diversion treatment of cerebral aneurysms: a multicenter study. 38
30670622 2019
18
Analysis of Flow Dynamics and Outcomes of Cerebral Aneurysms Treated with Intrasaccular Flow-Diverting Devices. 38
31395663 2019
19
Advanced 3D printed model of middle cerebral artery aneurysms for neurosurgery simulation. 38
31372773 2019
20
Cerebral Aneurysms due to Cardiac Myxoma. 38
31358100 2019
21
Tanshinone IIA attenuates cerebral aneurysm formation by inhibiting the NF‑κB‑mediated inflammatory response. 38
31257487 2019
22
Pre-procedural simulation for precision stent-assisted coiling of cerebral aneurysm. 38
30922200 2019
23
Determination of aneurysm volume critical for stability after coil embolization: A retrospective study of 3530 aneurysms. 38
31415892 2019
24
Correlation between laminar wall shear stress and growth of unruptured cerebral aneurysms: an in vivo assessment. 38
31404691 2019
25
Letter: Rescue Therapy for Procedural Complications Associated With Deployment of Flow-Diverting Devices in Cerebral Aneurysms. 38
31250902 2019
26
Balloon-assisted coiling of cerebral aneurysms with the dual-lumen Scepter XC balloon catheter: Experience at two high-volume centers. 38
30922198 2019
27
In Reply: Rescue Therapy for Procedural Complications Associated With Deployment of Flow-Diverting Devices in Cerebral Aneurysms. 38
31250892 2019
28
The "Brain Stress Timing" phenomenon and other misinterpretations of randomized clinical trial on aneurysmal subarachnoid hemorrhage. 38
30964054 2019
29
Development of a stent capable of the controlled release of basic fibroblast growth factor and argatroban to treat cerebral aneurysms: In vitro experiment and evaluation in a rabbit aneurysm model. 38
30653829 2019
30
Prediction of the extent of thrombus formation in the parent artery after endovascular occlusion of a distal anterior cerebral artery aneurysm using computational fluid dynamics. 38
31420275 2019
31
Lyophilizing thrombin powder-based treatment for hemostasis during coil embolization of ruptured cerebral aneurysm: Two case reports. 38
30803339 2019
32
A novel flow dynamics study of the intracranial veins using whole brain 4D-CTA. 38
31330333 2019
33
Osteopontin in the Cerebrospinal Fluid of Patients with Severe Aneurysmal Subarachnoid Hemorrhage. 38
31295895 2019
34
Multiple Cerebral Aneurysms Associated With Neurofibromatosis Type 1. 38
31080139 2019
35
Variable clinical features and genotype-phenotype correlations in 18 patients with late-onset Pompe disease. 38
31392188 2019
36
Loss of consciousness at onset of aneurysmal subarachnoid hemorrhage in good-grade patients. 38
31332702 2019
37
Novel pathogenic TGFBR1 and SMAD3 variants identified after cerebrovascular events in adult patients with Loeys-dietz syndrome. 38
31326520 2019
38
Serum Cadmium Level Is Positively Associated with Unruptured Intracranial Aneurysm Incidence. 38
30727706 2019
39
Obtaining Informed Consent Using Patient Specific 3D Printing Cerebral Aneurysm Model. 38
31290295 2019
40
Development of a Novel Canine Model of Ischemic Stroke: Skull Base Approach with Transient Middle Cerebral Artery Occlusion. 38
30898757 2019
41
Hydrocephalus Secondary to Intradural Extramedullary Malignant Melanoma of Spinal Cord. 38
31302270 2019
42
Case of Recurrent Artery of Heubner Aneurysm Masquerading as Partially Thrombosed A1 Aneurysm Radiologically. 38
31349077 2019
43
Interleukin-6 Promotes Murine Estrogen Deficiency-Associated Cerebral Aneurysm Rupture. 38
31264696 2019
44
Impact of age on cerebral aneurysm occlusion after flow diversion. 38
31072739 2019
45
Hemodynamic and morphological characteristics of a growing cerebral aneurysm. 38
31261117 2019
46
Refractory De Novo Multiple Cerebral Aneurysms After Radiotherapy and Multistaged "Open" Surgical Treatment for Low-Grade Glioma During Long-Term Follow-Up: A Case Report and Review of the Literature. 38
31225523 2019
47
In vivo cerebral aneurysm models. 38
31261125 2019
48
Nonindex Readmission After Ruptured Brain Aneurysm Treatment Is Associated with Higher Morbidity and Repeat Readmission. 38
31284063 2019
49
Lower Hemoglobin Levels Are Associated with Acute Seizures in Patients with Ruptured Cerebral Aneurysms. 38
31009781 2019
50
Letter to the Editor Regarding "Giant Cerebral Aneurysm in a Patient with Cowden Syndrome Treated with Surgical Clipping". 38
31266126 2019

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 MMP2 ELANE CTSB CST3 CCL2
2 extracellular region GO:0005576 9.43 MMP2 ELN ELANE CTSB CST3 CCL2
3 ficolin-1-rich granule lumen GO:1904813 9.26 CTSB CST3
4 collagen-containing extracellular matrix GO:0062023 8.92 MMP2 ELN ELANE CTSB

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.33 ELANE CTSB CST3
2 animal organ morphogenesis GO:0009887 9.26 ELN CCL2
3 extracellular matrix disassembly GO:0022617 8.96 MMP2 ELANE
4 collagen catabolic process GO:0030574 8.62 MMP2 CTSB

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.16 ELANE CST3
2 peptidase activity GO:0008233 9.13 MMP2 ELANE CTSB
3 serine-type endopeptidase activity GO:0004252 8.62 MMP2 ELANE

Sources for Cerebral Aneurysms

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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