Cerebral Aneurysms

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 53
Cerebral Aneurysm 54 71
Cerebral Arterial Aneurysm 71


External Ids:

UMLS 71 C0917996 C1290398

Summaries for Cerebral Aneurysms

NINDS : 53 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  A cerebral aneurysm can press on a nerve or surrounding tissue in the brain, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are more common in women than in men. These aneurysms can occur anywhere in the brain. Some small aneurysms may not show signs and are usually detected during imaging tests for other medical conditions. The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. A larger aneurysm that is steadily growing may produce symptoms such as numbness, pain above and behind the eye, and paralysis on one side of the face. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to intracranial aneurysm and vascular disease. An important gene associated with Cerebral Aneurysms is ELN (Elastin), and among its related pathways/superpathways are Degradation of the extracellular matrix and AGE-RAGE signaling pathway in diabetic complications. The drugs Cilostazol and Iron have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and testes, and related phenotype is neoplasm.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 412)
# Related Disease Score Top Affiliating Genes
1 intracranial aneurysm 32.2 MMP2 ELN CCL2
2 vascular disease 30.1 ELN CST3 CCL2
3 arteriosclerosis 29.8 ELN CST3 CCL2
4 homocysteinemia 29.5 ELN CST3 CCL2
5 peripheral artery disease 29.5 CST3 CCL2
6 proteasome-associated autoinflammatory syndrome 1 29.4 ELANE CCL2
7 lung disease 29.1 ELN ELANE CCL2
8 varicose veins 28.8 MMP2 ELN CCL2
9 myocardial infarction 28.4 MMP2 ELN CST3 CCL2
10 systemic lupus erythematosus 28.4 MMP2 ELANE CST3 CCL2
11 aortic aneurysm, familial abdominal, 1 28.3 MMP2 ELN ELANE CST3 CCL2
12 aneurysm 12.1
13 intracranial berry aneurysm 12.1
14 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 11.4
15 loeys-dietz syndrome 4 11.3
16 aneurysm, intracranial berry, 12 11.2
17 hydrocephalus 10.5
18 arteriovenous malformation 10.5
19 familial cerebral saccular aneurysm 10.5
20 headache 10.4
21 ocular motor apraxia 10.4
22 endocarditis 10.4
23 cardiac arrest 10.3
24 polycystic kidney disease 10.3
25 kidney disease 10.3
26 cerebrovascular disease 10.3
27 infective endocarditis 10.3
28 aphasia 10.3
29 renal hypertension 10.2
30 pica disease 10.2
31 head injury 10.2
32 fibromuscular dysplasia 10.2
33 autosomal dominant polycystic kidney disease 10.2
34 arteriovenous malformations of the brain 10.2
35 moyamoya disease 1 10.2
36 transient cerebral ischemia 10.2
37 aortic aneurysm 10.2
38 seizure disorder 10.2
39 coarctation of aorta 10.1
40 thrombosis 10.1
41 visual epilepsy 10.1
42 brain edema 10.1
43 carotid artery occlusion 10.1
44 vasculitis 10.1
45 neurofibromatosis 10.1
46 48,xyyy 10.1
47 ptosis 10.1
48 carotid stenosis 10.1
49 pituitary adenoma 10.1
50 acquired immunodeficiency syndrome 10.1

Graphical network of the top 20 diseases related to Cerebral Aneurysms:

Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

MGI Mouse Phenotypes related to Cerebral Aneurysms:

# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CST3 CTSB ELANE MMP2

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
Iron Approved, Experimental Phase 4 15438-31-0, 7439-89-6 27284 23925
Clopidogrel Approved Phase 4 113665-84-2, 120202-66-6 60606
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
Tenecteplase Approved Phase 4 191588-94-0
6 Antipyretics Phase 4
7 Respiratory System Agents Phase 4
8 Anti-Asthmatic Agents Phase 4
9 Neuroprotective Agents Phase 4
10 Bronchodilator Agents Phase 4
11 Prasugrel hydrochloride Phase 4 389574-19-0
12 Pharmaceutical Solutions Phase 4
13 Fibrinolytic Agents Phase 4
14 Purinergic P2Y Receptor Antagonists Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16 Neurotransmitter Agents Phase 4
17 calcium heparin Phase 4
18 Hematinics Phase 4
19 Epoetin alfa Phase 4 113427-24-0
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
Ticagrelor Approved Phase 3 274693-27-5 9871419
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
Milrinone Approved Phase 3 78415-72-2 4197
24 Anesthetics Phase 3
25 Tin Fluorides Phase 3
26 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2, Phase 3
27 Hypolipidemic Agents Phase 2, Phase 3
28 Lipid Regulating Agents Phase 2, Phase 3
29 Anticholesteremic Agents Phase 2, Phase 3
30 Antimetabolites Phase 2, Phase 3
31 Analgesics, Non-Narcotic Phase 3
32 Cyclooxygenase Inhibitors Phase 3
33 Analgesics Phase 3
34 Anti-Inflammatory Agents Phase 3
35 Antirheumatic Agents Phase 3
36 Anti-Inflammatory Agents, Non-Steroidal Phase 3
37 Phosphodiesterase Inhibitors Phase 3
38 Phosphodiesterase 3 Inhibitors Phase 3
39 Vasodilator Agents Phase 3
40 Protective Agents Phase 3
41 Astragalus Phase 2, Phase 3
42 Salicylates Phase 3
43 Cardiotonic Agents Phase 3
44 Vasoconstrictor Agents Phase 3
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
Polyestradiol phosphate Approved Phase 2 28014-46-2
Nimodipine Approved, Investigational Phase 1, Phase 2 66085-59-4 4497
Clotrimazole Approved, Vet_approved Phase 2 23593-75-1 2812
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353

Interventional clinical trials:

(show top 50) (show all 108)
# Name Status NCT ID Phase Drugs
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
2 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function in Patients Undergoing Intracranial Aneurysm Surgery. Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
3 Comparison of Dual-Antiplatelet and Triple-Antiplatelet Preparation Using P2Y12 Assay in Patients With High On-Treatment Platelet Reactivity Undergoing Stent-Assisted Coil Embolization for An Unruptured Intracranial Aneurysm Recruiting NCT03581409 Phase 4 Aspirin;Prasugrel;Clopidogrel;Cilostazol
4 The Effect of Ferric Carboximaltose on Intra-myocardial Iron Load Assessed by Cardiac Magnetic Resonance in Patients With Heart Failure With Reduced Ejection Fraction (HFREF). Not yet recruiting NCT03871699 Phase 4 Ferric carboxymaltose
5 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
6 A Double Blinded, Placebo Controlled, Pilot Study to Evaluate the Safety of Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
7 TRIANA: A Randomized Trial to Compare the Efficay and Safety of Thrombolysis With Primary Angioplasty as Initial Reperfusion Therapy in Older Patients (>= 75 Years Old) With Acute Myocardial Infarction Terminated NCT00257309 Phase 4 Tenecteplase + UFH (+ clopidogrel, since 01/97)
8 EARLYdrain - Prospective Outcome Study of Early Lumbar Drainage in Aneurysmal Subarachnoid Hemorrhage Completed NCT01258257 Phase 3
9 High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage: Is it Better? Completed NCT01077206 Phase 2, Phase 3 Simvastatin
10 Ticagrelor Versus Clopidogrel for Platelet Inhibition in Patients Undergoing Neurovascular Stenting for Intracranial Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
11 Utility of Lung Clearance Index Score as a Noninvasive Marker of Small Airways Disease Recruiting NCT03241420 Phase 3
12 Efficacy Study of Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT03271697 Phase 2, Phase 3 Astragalus Membranaceus;Placebo
13 Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain Aneurysms(EVOLVE): A Phase 3 Multicenter Randomized Study Not yet recruiting NCT04192955 Phase 3 Acetyl Salicylate
14 Milrinone Infusion for VAsospam Treatment in Subarachnoid hemoRrhage Not yet recruiting NCT04362527 Phase 3 Milrinone 1 Mg/mL Solution for Injection;Saline solution for injection
15 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
16 Estrogen Therapy as Prevention in the Progression of Aneurysm Unknown status NCT01895881 Phase 2 Estradiol;Placebo
17 Hypertonic Saline Solution in Aneurysmal Subarachnoid Hemorrhage: A Randomized - Phase II Single Blinded Clinical Trial Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
18 Safety and Pharmacokinetic Evaluation of Sodium Nitrite Injection for the Prevention of Post-Subarachnoid Hemorrhage Induced Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
19 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
20 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
21 Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms Not yet recruiting NCT04141020 Phase 2 Sirolimus
22 Deferiprone Trial for Subarachnoid Hemorrhage (SAH) Patients Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
23 Evaluation of Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage From a Cerebral Aneurysm Terminated NCT02176837 Phase 2 Sodium Nitrite
24 Safety and Efficacy Trial of Sildenafil Citrate in Attenuation of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT00871065 Phase 2 Sildenafil citrate
25 Short Term Application of Sevoflurane in Patients With Subarachnoid Haemorrhage: a Feasibility and Safety Study Withdrawn NCT02946437 Phase 2 Sevoflurane;Propofol;Midazolam
26 The Effect of Autologous Adipose Mesenchymal Stem Cells in Treatment of Airway Injury in Patients Exposed to Sulfur Mustard Unknown status NCT02749448 Phase 1
27 Aspirin as a Promising Agent to Attenuate Inflammation in the Wall of Human Cerebral Aneurysms Completed NCT01710072 Phase 1 aspirin
28 Efficacy Of Ultrasound Guided Stellate Ganglion Block To Relieve Vasospasm Following Clipping Of Cerebral Aneurysm Completed NCT02775318 Phase 1 Bupivacaine
29 Prophylactic Remote Ischemic Preconditioning for Cerebral Vasospasm Following Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
30 Phase I Safety, Blood Brain Barrier Permeability and Potential Efficacy of Etanercept for Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT01865630 Phase 1 Etanercept
31 Safety of Rapid Ventricular Pacing During Cerebral Aneurysm Surgery by Multimodal Neuromonitoring Unknown status NCT03185091
32 Preoperative Assessment and Individualized Operation Optimization of Acute Ruptured Cerebral Aneurysms Unknown status NCT02977520
33 Epidemiology of Cerebral Aneurysms With MRA in China in Middle-aged or Elder Person: a Population-based Survey Unknown status NCT00926172
34 Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms Unknown status NCT02345395
35 Searching a Dysfunction of Corticotropic and Thyrotropin Axis During the Acute Phase ( ≤48h ) of a Subarachnoid Hemorrhage Secondary to Spontaneous Rupture of Cerebral Aneurysm: Impact on the Incidence of Complications and Recovery at 1 Month Unknown status NCT03655509
36 Effects of Valproic Acid and Magnesium Sulphate on Rocuronium Requirement and Postoperative Analgesia in Patients Undergoing Craniotomy for Cerebrovascular Surgery Unknown status NCT01460563 Magnesium Sulfate;0.9% saline;0.9% saline
37 Effect of Dexmedetomidine on Maintenance and Recovery of Cranial Aneurysm Surgery Unknown status NCT03355534 Intravenous dexmedetomidine;nasal dexmedetomidine;intravenous saline;nasal saline
38 Predictive Values of Serum Adiponectin Levels in Aneurysmal Subarachnoid Hemorrhage. Unknown status NCT02814162
39 To Investigate the Coexistence of Atherosclerotic Intracranial Arterial Stenosis With Intracranial Aneurysms Unknown status NCT02795078 conservative treatment
40 The Neuroprotection of Sevoflurane Preconditioning on Perioperative Ischemia-reperfusion Injury During Intracranial Aneurysm Surgery Unknown status NCT01204268
41 The Role of Remote Ischemic Preconditioning in the Prevention of Ischemic Brain Damage During Intracranial Aneurysm Treatment (RIPAT) - A Prospective Randomized Exploratory Study Unknown status NCT02162654
42 Detection of Intracranial Aneurysm With Non-enhanced, Three-dimensional Time-of-flight Magnetic Resonance Angiography(3D−TOF−MRA): a Prospective Comparison With Three-dimensional Reconstructed Digital Subtraction Angiography (3D RDSA) Unknown status NCT01031147
43 Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02995928
44 Vitamin D Effect on Subarachnoid Hemorrhage Unknown status NCT03482843
45 Evaluation of New Neuroinflammation Markers in Subarachnoid Haemorrhage Patients: a Pilot Study Unknown status NCT03411746
46 Linkage Analysis of Familial Intracranial Aneurysms Completed NCT00011856
47 Barrow Ruptured Aneurysm Study Completed NCT01593267
48 The Use of the Classic Laryngeal Mask Airway in Patients With Cerebral Aneurysm Undergoing Endovascular Therapy Completed NCT03288519
49 Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing. Completed NCT00556309
50 Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain Completed NCT03281395

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

Brain, Kidney, Testes, Endothelial, Eye, Heart, Pituitary

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 6065)
# Title Authors PMID Year
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm. 61 54
17714769 2007
Management of polycystic liver disease. 54 61
15701294 2005
[In situ localization of mRNA gelatinases in cerebral aneurysms]. 54 61
11715488 1999
Morphometric analysis of reticular and elastin fibers in the cerebral arteries of patients with intracranial aneurysms. 54 61
2362672 1990
Role of activin receptor-like kinase 1 in vascular development and cerebrovascular diseases. 61
32246621 2020
Relationshıp of spontaneous subarachnoid haemorrhage and cerebral aneurysm to serum Visfatin and Nesfatin-1 levels. 61
32311618 2020
Treatment of Acutely Ruptured Cerebral Aneurysms With the Woven EndoBridge Device: Experience Post-FDA Approval. 61
32357228 2020
Circle of Willis abnormalities and their clinical importance in ageing brains: A cadaveric anatomical and pathological study. 61
32165168 2020
Treatment and diagnosis of cerebral aneurysms in the post-International Subarachnoid Aneurysm Trial (ISAT) era: trends and outcomes. 61
31959634 2020
Cerebral venous congestion correlates to acute aneurysm rupture: An illustrative case with Doppler ultrasonography study. 61
32181376 2020
Safety and efficacy of endovascular treatment of ruptured tiny cerebral aneurysms compared with ruptured larger aneurysms. 61
31930939 2020
Thromboembolism during coiling of intracranial aneurysms: predictors and clinical outcome. 61
32489493 2020
Hemodynamics of Cerebral Aneurysms: Connecting Medical Imaging and Biomechanical Analysis. 61
32212833 2020
Adverse intraoperative events during surgical repair of ruptured cerebral aneurysms: a systematic review. 61
32542428 2020
Endoscopic endonasal clipping of cerebral aneurysms: started from the bottom, now we are here! 61
30514072 2020
Incomplete stent apposition of low-profile visualized intraluminal support stents in the treatment of cerebral aneurysms. 61
31818969 2020
Factors related to adverse events during endovascular coil embolization for ruptured cerebral aneurysms. 61
31980542 2020
Factors affecting recurrence and management of recurrent cerebral aneurysms after initial coiling. 61
31992106 2020
Utility of platelet function testing in stent-assisted coiling of cerebral aneurysms. 61
31856647 2020
Thrombosis of a basilar perforator aneurysm associated with pontine infarction in a patient with systemic lupus erythematosus. 61
32300472 2020
[A Case of Unruptured Cerebral Aneurysm Arising from Duplicate Origin of the Middle Cerebral Artery]. 61
32572003 2020
Neuroangiography: Review of Anatomy, Periprocedural Management, Technique, and Tips. 61
32419729 2020
[Ruptured Aneurysm of an Aplastic or Twig-like Middle Cerebral Artery with Ring Finger Protein 213 Mutation:A Case Report]. 61
32572006 2020
High prevalence of arterial dissection in patients with Loeys-Dietz syndrome and cerebral aneurysm. 61
32129152 2020
Penumbral Salvage by Delayed Clip Reposition 19 Hours After Cerebral Aneurysm Clipping-Induced Ischemia Results in Neurologic Restitution-Correlation with Indocyanine Green Videoangiography and FLOW 800 Measurements. 61
32142943 2020
Lower complication rates associated with transradial versus transfemoral flow diverting stent placement. 61
32487766 2020
Risk factors for ischemic complications in vascular reconstructive surgeries. 61
32146236 2020
Preliminary in vitro angiographic comparison of the flow diversion behavior of Evolve and Pipeline devices. 61
31723048 2020
Ischemic Tolerance Evaluated by Computed Tomography Perfusion during Balloon Test Occlusion. 61
32295733 2020
Discrepancy in Neurologic Outcomes Following Aneurysmal Subarachnoid Hemorrhage as a Function of Socioeconomic Class. 61
32217180 2020
Experimental Analysis of Intra-luminal Pressure by Contrast Injection during Mechanical Thrombectomy: Simulation of Rupture Risk of Hidden Cerebral Aneurysm in Tandem Occlusion with Blind Alley. 61
32448828 2020
The Iatrogenic Development of an Anterior Cerebral Artery Pseudoaneurysm during Lamina Terminalis Fenestration-Genesis, Diagnosis and Therapy: Lessons Learned. 61
32526835 2020
Transradial Approach as the Primary Vascular Access with a 6-Fr Simmons Guiding Sheath for Anterior Circulation Interventions: A Single-Center Case Series of 130 Consecutive Patients. 61
32165342 2020
Vascular Ehlers-Danlos Syndrome: Literature review and surgical management of intracranial vascular complications. 61
32197145 2020
The Incidence and Etiologies of Third Cranial Nerve Palsy in Koreans: A 10-year Nationwide Cohort Study. 61
32506973 2020
Recent advances in stent-assisted coiling of cerebral aneurysms. 61
32500761 2020
Patient Education and Engagement Through Multimedia: A Prospective Pilot Study on Health Literacy in Patients with Cerebral Aneurysms. 61
32234355 2020
4D-CT angiography versus 3D-rotational angiography as the imaging modality for computational fluid dynamics of cerebral aneurysms. 61
31772042 2020
A pilot study using a machine-learning approach of morphological and hemodynamic parameters for predicting aneurysms enhancement. 61
32514728 2020
The contribution of wall shear stress insult to the growth of small unruptured cerebral aneurysms in longitudinal 3D-TOF-MRA. 61
32251870 2020
Platelet Function Testing with a VerifyNow-Directed Personalized Antiplatelet Strategy and Associated Rates of Thromboembolic Complications After Pipeline Embolization for Complex Cerebral Aneurysms. 61
32194270 2020
Electroconvulsive therapy in patients with cerebral aneurysms taking an anticoagulant or antiplatelet-report on three cases and review of the literature. 61
32335467 2020
Coil migration during or after endovascular coiling of cerebral aneurysms. 61
31662464 2020
Endovascular Retreatment of Cerebral Aneurysms Previously Treated with Endovascular Embolization. 61
31746449 2020
Predictors of Cerebral Aneurysm Rupture after Coil Embolization: Single-Center Experience with Recanalized Aneurysms. 61
32381548 2020
Make Clipping Great Again: Microsurgery for Cerebral Aneurysms by Dual-Trained Neurosurgeons. 61
32058116 2020
Giant Cerebral Aneurysms: Comparing CTA, MRA, and Digital Subtraction Angiography Assessments. 61
32324333 2020
Identification of Vortex Cores in Cerebral Aneurysms on 4D Flow MRI. 61
32241769 2020
Mechanical thrombectomy for delayed thrombosis of a Pipeline Embolization Device. 61
32387404 2020
Flow-diverting stent and delayed intracranial bleeding: the case for discussing acquired von Willebrand disease. 61
32406779 2020

Variations for Cerebral Aneurysms

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 MMP2 ELANE CTSB CST3 CCL2
2 extracellular region GO:0005576 9.43 MMP2 ELN ELANE CTSB CST3 CCL2
3 collagen-containing extracellular matrix GO:0062023 8.92 MMP2 ELN ELANE CTSB

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.5 ELANE CTSB CST3
2 extracellular matrix disassembly GO:0022617 9.26 MMP2 ELANE
3 positive regulation of smooth muscle cell proliferation GO:0048661 9.16 MMP2 ELANE
4 embryo implantation GO:0007566 8.96 MMP2 CST3
5 collagen catabolic process GO:0030574 8.62 MMP2 CTSB

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.16 ELANE CST3
2 peptidase activity GO:0008233 9.13 MMP2 ELANE CTSB
3 endopeptidase activity GO:0004175 8.8 MMP2 ELANE CTSB

Sources for Cerebral Aneurysms

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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