MCID: CRB018
MIFTS: 20

Cerebral Lipidosis

Categories: Neuronal diseases

Aliases & Classifications for Cerebral Lipidosis

MalaCards integrated aliases for Cerebral Lipidosis:

Name: Cerebral Lipidosis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10742
ICD9CM 35 330.1
SNOMED-CT 68 16517004
UMLS 73 C0007788

Summaries for Cerebral Lipidosis

MalaCards based summary : Cerebral Lipidosis is related to gangliosidosis gm1 and tay-sachs disease. An important gene associated with Cerebral Lipidosis is GLB1 (Galactosidase Beta 1), and among its related pathways/superpathways are Glycosaminoglycan metabolism and Chondroitin sulfate/dermatan sulfate metabolism.

Related Diseases for Cerebral Lipidosis

Diseases related to Cerebral Lipidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 gangliosidosis gm1 29.7 HEXA GLB1
2 tay-sachs disease 29.6 HEXA GLB1
3 metachromatic leukodystrophy 9.9
4 leukodystrophy 9.9
5 dementia 9.9
6 speech disorder 9.9
7 myoclonus 9.9
8 gangliosidosis gm2 9.9 HEXA GLB1
9 mucopolysaccharidosis, type vii 9.9 HEXA GLB1
10 scheie syndrome 9.8 HEXA GLB1
11 mucolipidosis iv 9.8 HEXA GLB1
12 sphingolipidosis 9.8 HEXA GLB1
13 lipid storage disease 9.8 HEXA GLB1
14 lysosomal storage disease 9.7 HEXA GLB1

Graphical network of the top 20 diseases related to Cerebral Lipidosis:



Diseases related to Cerebral Lipidosis

Symptoms & Phenotypes for Cerebral Lipidosis

Drugs & Therapeutics for Cerebral Lipidosis

Search Clinical Trials , NIH Clinical Center for Cerebral Lipidosis

Genetic Tests for Cerebral Lipidosis

Anatomical Context for Cerebral Lipidosis

Publications for Cerebral Lipidosis

Articles related to Cerebral Lipidosis:

(show all 13)
# Title Authors Year
1
A sporadic case of cerebral lipidosis in an adult (Kufs)--pathological and histochemical findings. ( 5068472 )
1972
2
Studies on cerebral lipidosis. Enzymatic study of G M2 -gangliosidosis. ( 4998880 )
1971
3
Studies on cerebral lipidosis. Prenatal diagnosis of Tay-Sachs disease. ( 5004836 )
1971
4
Gm1-gangliosidosis and juvenile cerebral lipidosis. Clinical, histochemical, and chemical study. ( 5089899 )
1971
5
Studies on cerebral lipidosis. Enzymatic diagnosis of metachromatic leukodystrophy. ( 4993715 )
1970
6
Adult cerebral lipidosis. A case of Kufs's disease. ( 5457866 )
1970
7
Progressive dementia in childhood due to cerebral lipidosis. ( 5349188 )
1969
8
EEG patterns in juvenile cerebral lipidosis. ( 4184160 )
1969
9
Cerebral lipidosis in the dog. ( 5656558 )
1968
10
Early childhood cerebral lipidosis with prominent myoclonus. Ultrastructural and histochemical studies of a cerebral biopsy. ( 5634370 )
1968
11
An electronmicroscopical study of a case of atypical cerebral lipidosis. ( 4963519 )
1967
12
Evolution of a characteristic speech disorder in juvenile cerebral lipidosis (Spielmeyervogt Syndrome). ( 5857766 )
1965
13
Cerebral lipidosis: an electroencephalographic study. ( 12978168 )
1952

Variations for Cerebral Lipidosis

Expression for Cerebral Lipidosis

Search GEO for disease gene expression data for Cerebral Lipidosis.

Pathways for Cerebral Lipidosis

Pathways related to Cerebral Lipidosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.18 GLB1 HEXA
2
Show member pathways
11.91 GLB1 HEXA
3
Show member pathways
11.77 GLB1 HEXA
4 11.41 GLB1 HEXA
5
Show member pathways
11.2 GLB1 HEXA
6
Show member pathways
10.6 GLB1 HEXA
7
Show member pathways
10.26 GLB1 HEXA
8 9.88 GLB1 HEXA

GO Terms for Cerebral Lipidosis

Cellular components related to Cerebral Lipidosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysosome GO:0005764 8.96 GLB1 HEXA
2 lysosomal lumen GO:0043202 8.62 GLB1 HEXA

Biological processes related to Cerebral Lipidosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate metabolic process GO:0005975 9.26 GLB1 HEXA
2 metabolic process GO:0008152 9.16 GLB1 HEXA
3 glycosphingolipid metabolic process GO:0006687 8.96 GLB1 HEXA
4 keratan sulfate catabolic process GO:0042340 8.62 GLB1 HEXA

Molecular functions related to Cerebral Lipidosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity, acting on glycosyl bonds GO:0016798 8.62 GLB1 HEXA

Sources for Cerebral Lipidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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