MCID: CRB036
MIFTS: 31

Cerebral Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cerebral Meningioma

MalaCards integrated aliases for Cerebral Meningioma:

Name: Cerebral Meningioma 12 56 15 74
Meningioma of Cerebrum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6112
NCIt 51 C4807
UMLS 74 C0542564

Summaries for Cerebral Meningioma

MalaCards based summary : Cerebral Meningioma, also known as meningioma of cerebrum, is related to meningioma, familial and spinal meningioma, and has symptoms including seizures and headache. An important gene associated with Cerebral Meningioma is DRD1 (Dopamine Receptor D1), and among its related pathways/superpathways are Cytokine Signaling in Immune system and MicroRNAs in cardiomyocyte hypertrophy. Affiliated tissues include thyroid, skin and breast, and related phenotypes are Increased HDAC inhibitor resistance and growth/size/body region

Related Diseases for Cerebral Meningioma

Diseases related to Cerebral Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 10.2
2 spinal meningioma 10.2
3 secretory meningioma 10.2
4 adenoma 9.9
5 parathyroid adenoma 9.9
6 thyroid cancer, nonmedullary, 1 9.7
7 anorexia nervosa 9.7
8 mucocutaneous ulceration, chronic 9.7
9 keratopathy 9.7
10 thyroid cancer 9.7
11 papillary carcinoma 9.7
12 skin carcinoma 9.7
13 actinomycosis 9.7
14 tremor 9.7
15 breast disease 9.7 EGF PRLR
16 somatization disorder 9.6 LIF LIFR
17 hypothyroidism, central, and testicular enlargement 9.6 LIF LIFR

Graphical network of the top 20 diseases related to Cerebral Meningioma:



Diseases related to Cerebral Meningioma

Symptoms & Phenotypes for Cerebral Meningioma

UMLS symptoms related to Cerebral Meningioma:


seizures, headache

GenomeRNAi Phenotypes related to Cerebral Meningioma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased HDAC inhibitor resistance GR00115-A-0 8.62 LIF LIFR

MGI Mouse Phenotypes related to Cerebral Meningioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.65 DRD1 EGF LIF LIFR PRLR
2 endocrine/exocrine gland MP:0005379 9.62 EGF LIF LIFR PRLR
3 adipose tissue MP:0005375 9.54 DRD1 LIF PRLR
4 integument MP:0010771 9.46 DRD1 EGF LIF PRLR
5 reproductive system MP:0005389 9.26 EGF LIF LIFR PRLR
6 vision/eye MP:0005391 8.92 DRD1 EGF LIF PRLR

Drugs & Therapeutics for Cerebral Meningioma

Search Clinical Trials , NIH Clinical Center for Cerebral Meningioma

Genetic Tests for Cerebral Meningioma

Anatomical Context for Cerebral Meningioma

MalaCards organs/tissues related to Cerebral Meningioma:

42
Thyroid, Skin, Breast

Publications for Cerebral Meningioma

Articles related to Cerebral Meningioma:

(show all 21)
# Title Authors Year
1
Participation restrictions in patients after surgery for cerebral meningioma. ( 30264851 )
2018
2
Uncommon association of cerebral meningioma, parathyroid adenoma and papillary thyroid carcinoma in a patient harbouring a rare germline variant in the CDKN1B gene. ( 26762354 )
2016
3
Cerebral meningioma presenting as dystonic head tremor. ( 24259285 )
2014
4
Cognitive and emotional problems in patients after cerebral meningioma surgery. ( 24763925 )
2014
5
Unexpected finding of cerebral meningioma on (11)C-PiB PET. ( 23429388 )
2013
6
An incidental finding of cerebral meningioma on 99mTc-TRODAT-1 dopamine transporter SPECT/CT. ( 22889784 )
2012
7
Unexpected finding on I-123 FP-CIT SPECT leading to the diagnosis of cerebral meningioma. ( 21220989 )
2011
8
Neuroparalytic keratopathy as the first sign of a cerebral meningioma. ( 17894293 )
2007
9
An unusual association of cerebral meningioma, parathyroid adenoma and thyroid papillary carcinoma. ( 16724700 )
2006
10
Radiotherapy after surgery for benign cerebral meningioma. ( 15066300 )
2004
11
Can the calcitonin used for a shoulder-hand syndrome have a role in the revelation of a cerebral meningioma? ( 15589451 )
2004
12
Radiation-induced skin ulcer, cerebral meningioma, and skin cancer following radiation and radium treatment for actinomycosis. ( 11994636 )
2002
13
[Estrogen and progesterone receptors in cerebral meningioma and their clinical value]. ( 12378940 )
2002
14
"Anorexia saved my life": coincidental anorexia nervosa and cerebral meningioma. ( 11746295 )
2001
15
Post-operative computed tomography in two dogs with cerebral meningioma. ( 11052366 )
2000
16
Formation of autocrine loops in human cerebral meningioma tissue by leukemia inhibitor factor, interleukin-6, and oncostatin M: inhibition of meningioma cell growth in vitro by recombinant oncostatin M. ( 9488310 )
1998
17
Inhibition of proliferation of human cerebral meningioma cells by suramin: effects on cell growth, cell cycle phases, extracellular growth factors, and PDGF-BB autocrine growth loop. ( 7897522 )
1995
18
Results of craniotomy for the treatment of cerebral meningioma in 42 cats. ( 8191679 )
1994
19
Presence of dopamine D1 receptors and absence of dopamine D2 receptors in human cerebral meningioma tissue. ( 1385626 )
1992
20
Radiation-induced cerebral meningioma: a recognizable entity. ( 6593438 )
1984
21
Foot and leg symptoms referrable to bilateral cerebral meningioma--a case report. ( 14028016 )
1962

Variations for Cerebral Meningioma

Expression for Cerebral Meningioma

Search GEO for disease gene expression data for Cerebral Meningioma.

Pathways for Cerebral Meningioma

GO Terms for Cerebral Meningioma

Cellular components related to Cerebral Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.26 EGF LIF LIFR PRLR
2 receptor complex GO:0043235 8.8 EGF LIFR PRLR

Biological processes related to Cerebral Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.5 EGF LIF LIFR
2 positive regulation of gene expression GO:0010628 9.43 DRD1 EGF LIF
3 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.37 EGF LIF
4 embryo implantation GO:0007566 9.16 LIF PRLR
5 activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8.96 EGF PRLR
6 leukemia inhibitory factor signaling pathway GO:0048861 8.62 LIF LIFR

Molecular functions related to Cerebral Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.16 EGF LIF
2 cytokine binding GO:0019955 8.96 LIFR PRLR
3 cytokine receptor activity GO:0004896 8.62 LIFR PRLR

Sources for Cerebral Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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