MCID: CRB024
MIFTS: 33

Cerebral Neuroblastoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cerebral Neuroblastoma

MalaCards integrated aliases for Cerebral Neuroblastoma:

Name: Cerebral Neuroblastoma 12 15
Neuroblastoma of Brain 12 73
Neuroblastoma of the Cerebral Hemisphere 12
Neuroblastoma of Cerebrum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4164
NCIt 50 C4826
UMLS 73 C0559458

Summaries for Cerebral Neuroblastoma

Disease Ontology : 12 A brain cancer that is characterized by small, round and blue cells with rosette patterns on histology, that has material basis in abnormally proliferating cells and derives from precursor cells called blast cells.

MalaCards based summary : Cerebral Neuroblastoma, also known as neuroblastoma of brain, is related to neuroblastoma and glioma susceptibility 1. An important gene associated with Cerebral Neuroblastoma is ENO2 (Enolase 2), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Neuroscience. Affiliated tissues include brain, pituitary and lung, and related phenotype is normal.

Related Diseases for Cerebral Neuroblastoma

Diseases related to Cerebral Neuroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 202)
# Related Disease Score Top Affiliating Genes
1 neuroblastoma 30.6 ENO2 NGF SYP TP53
2 glioma susceptibility 1 29.8 GFAP TP53
3 brain injury 10.3 ENO2 GFAP
4 traumatic brain injury 10.3 ENO2 GFAP
5 ileum cancer 10.3 ENO2 GFAP
6 neurilemmoma 10.3 ENO2 GFAP
7 scrapie 10.3 ENO2 GFAP
8 dysgerminoma of ovary 10.3 ENO2 GFAP
9 chondrosarcoma, extraskeletal myxoid 10.2 ENO2 SYP
10 malignant pheochromocytoma 10.2 ENO2 SYP
11 adrenal rest tumor 10.2 ENO2 SYP
12 cranial nerve malignant neoplasm 10.2 ENO2 SYP
13 olfactory neuroblastoma 10.2 ENO2 SYP
14 pineal parenchymal tumor of intermediate differentiation 10.2 ENO2 SYP
15 mixed ductal-endocrine carcinoma 10.2 ENO2 SYP
16 horseshoe kidney 10.2 ENO2 SYP
17 cerebellopontine angle tumor 10.2 GFAP SYP
18 pilomyxoid astrocytoma 10.2 GFAP SYP
19 intracranial cysts 10.2 ENO2 GFAP
20 primitive neuroectodermal tumor of the cervix uteri 10.2 ENO2 GFAP
21 melanotic medulloblastoma 10.2 ENO2 GFAP
22 carotid body cancer 10.2 ENO2 SYP
23 malignant sertoli cell tumor 10.2 ENO2 SYP
24 urinary bladder small cell neuroendocrine carcinoma 10.2 ENO2 SYP
25 cerebellar medulloblastoma 10.2 ENO2 GFAP
26 auditory system cancer 10.2 ENO2 SYP
27 sinonasal undifferentiated carcinoma 10.2 ENO2 SYP
28 connective tissue cancer 10.2 ENO2 TP53
29 liver angiosarcoma 10.2 ENO2 TP53
30 gallbladder small cell carcinoma 10.2 ENO2 SYP
31 germ cell and embryonal cancer 10.2 ENO2 TP53
32 pancreatic somatostatinoma 10.2 ENO2 SYP
33 plexiform schwannoma 10.2 ENO2 GFAP
34 cutaneous ganglioneuroma 10.2 ENO2 SYP
35 extrahepatic bile duct adenocarcinoma 10.2 ENO2 SYP
36 desmoplastic infantile ganglioglioma 10.2 GFAP SYP
37 extraventricular neurocytoma 10.2 GFAP SYP
38 small cell carcinoma of the bladder 10.2 ENO2 SYP
39 achalasia 10.2 ENO2 TP53
40 papillary tumor of the pineal region 10.2 ENO2 SYP
41 sensory organ benign neoplasm 10.2 ENO2 SYP
42 orbital cancer 10.2 ENO2 SYP
43 middle ear adenoma 10.2 ENO2 SYP
44 lung combined type small cell carcinoma 10.2 GFAP SYP
45 pulmonary large cell neuroendocrine carcinoma 10.2 ENO2 SYP
46 brain glioma 10.2 GFAP TP53
47 necrotizing sialometaplasia 10.2 GFAP TP53
48 large cell neuroendocrine carcinoma 10.2 ENO2 SYP
49 microcystic meningioma 10.2 ENO2 GFAP
50 cauda equina neoplasm 10.2 ENO2 SYP

Graphical network of the top 20 diseases related to Cerebral Neuroblastoma:



Diseases related to Cerebral Neuroblastoma

Symptoms & Phenotypes for Cerebral Neuroblastoma

MGI Mouse Phenotypes related to Cerebral Neuroblastoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 9.1 ANXA5 FCGR1A GFAP NGF SYP TP53

Drugs & Therapeutics for Cerebral Neuroblastoma

Search Clinical Trials , NIH Clinical Center for Cerebral Neuroblastoma

Genetic Tests for Cerebral Neuroblastoma

Anatomical Context for Cerebral Neuroblastoma

MalaCards organs/tissues related to Cerebral Neuroblastoma:

41
Brain, Pituitary, Lung, Ovary, Spinal Cord, Cervix, Pineal

Publications for Cerebral Neuroblastoma

Articles related to Cerebral Neuroblastoma:

(show all 45)
# Title Authors Year
1
Serial Diffusion-Weighted and Conventional MR Imaging in Primary Cerebral Neuroblastoma Treated with Radiotherapy and Chemotherapy. A Case Report and Literature Review. ( 25196613 )
2014
2
Cerebral neuroblastoma and pituitary adenocarcinoma in two budgerigars (Melopsittacus undulatus). ( 22312997 )
2011
3
Primary cerebral neuroblastoma. ( 16038236 )
2005
4
Primary cerebral neuroblastoma: a case treated with adjuvant chemotherapy and radiotherapy. ( 15214753 )
2004
5
Giant cystic primary cerebral neuroblastoma in a child and solid primary cerebral neuroblastoma in an adult: two case reports. ( 15177410 )
2004
6
A case of primary cerebral neuroblastoma in adolescence. ( 11966589 )
2002
7
Primary cerebral neuroblastoma: a case report and review. ( 12180794 )
2002
8
TI-201 scintigraphy in cerebral neuroblastoma. ( 8846580 )
1996
9
Cystic metastatic cerebral neuroblastoma. ( 8577567 )
1995
10
Neuroblastomas of the central nervous system--clinicopathological features of a cerebellar neuroblastoma in comparison with a metastatic cerebral neuroblastoma. ( 7967443 )
1994
11
Congenital primary cerebral neuroblastoma. ( 7896398 )
1994
12
Intraventricular cerebral neuroblastoma. Analysis of subtypes and comparison with hemispheric neuroblastoma. ( 8080360 )
1994
13
Prenatal diagnosis of cerebral neuroblastoma by fetal brain biopsy. ( 8345560 )
1993
14
Cranio-cerebral neuroblastoma. ( 1797678 )
1991
15
A case of calcified cerebral neuroblastoma diagnosed cytologically in intraoperative imprint smears. ( 2028701 )
1991
16
Primary cerebral neuroblastoma: CT and MR findings in 12 cases. ( 2105591 )
1990
17
Primary cerebral neuroblastoma: CT and MR findings in 12 cases. ( 2107684 )
1990
18
Primary cerebral neuroblastoma. ( 2734857 )
1989
19
Magnetic resonance imaging in primary cerebral neuroblastoma. ( 2716996 )
1989
20
High-grade cerebral neuroblastoma: a case study. ( 2542739 )
1989
21
Primary cerebral neuroblastoma (neurocytoma) in adults. ( 2674338 )
1989
22
Third ventricular primary cerebral neuroblastoma. Electron-microscopic and immunohistochemical study. ( 3413672 )
1988
23
Cerebral gliomas with palisading necrosis: glioblastoma multiforme or high grade cerebral neuroblastoma? A light and electron microscopical study of three cases. ( 2840628 )
1987
24
Palisading pattern in cerebral neuroblastoma mimicking the primitive polar spongioblastoma. An ultrastructural study. ( 3604582 )
1987
25
Palisades in primary cerebral neuroblastoma simulating so-called polar spongioblastoma. A light and electron microscopical study of an adult case. ( 2436498 )
1987
26
Primary cerebral neuroblastoma--a case report with autopsy findings. ( 3570350 )
1986
27
Differentiated cerebral neuroblastoma: a tumor in need of discovery. ( 3997144 )
1985
28
Composite cerebral neuroblastoma and astrocytoma. A mixed central neuroepithelial tumor. ( 4027875 )
1985
29
Intraventricular primary cerebral neuroblastoma in adults: report of three cases. ( 4010911 )
1985
30
The biological behavior of primary cerebral neuroblastoma: a reappraisal of the clinical course in a series of 70 cases. ( 6431897 )
1984
31
Primary cerebral neuroblastoma. ( 6716155 )
1984
32
Primary cerebral neuroblastoma. Long-term follow-up review and therapeutic guidelines. ( 6886755 )
1983
33
Cerebral neuroblastoma in an adult. Case report, pharmacology, and review of the literature. ( 6845143 )
1983
34
Primary cerebral neuroblastoma in an adult man. ( 7302823 )
1981
35
A cerebral neuroblastoma with extracranial metastases. ( 7280973 )
1981
36
Dense core vesicles in the desmoplastic variant of cerebral neuroblastoma. ( 7376830 )
1980
37
Primary cerebral neuroblastoma. Case report with light microscopy, tissue culture and electron microscopy study. ( 7413260 )
1980
38
The cytology of cerebral neuroblastoma. ( 6932148 )
1980
39
Cerebral neuroblastoma with elevated nerve growth factor. ( 7407431 )
1980
40
Primary cerebral neuroblastoma. ( 581843 )
1979
41
Spontaneous extracranial metastasis of cerebral neuroblastoma. ( 524254 )
1979
42
Primary cerebral neuroblastoma: a light and electron microscopic study. ( 636842 )
1978
43
Cerebral neuroblastoma. ( 153641 )
1978
44
Primary cerebral neuroblastoma. A clinicopathological study of 35 cases. ( 1030655 )
1976
45
A cerebral neuroblastoma with unusual fibrous tissue reaction. ( 5936315 )
1966

Variations for Cerebral Neuroblastoma

Expression for Cerebral Neuroblastoma

Search GEO for disease gene expression data for Cerebral Neuroblastoma.

Pathways for Cerebral Neuroblastoma

Pathways related to Cerebral Neuroblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.4 CSF3 IGF2 NGF TP53
2 11.79 ENO2 GFAP NGF SYP
3 10.97 FCGR1A NGF
4 10.7 GFAP NGF SYP
5 10.36 CSF3 GFAP IGF2 NGF

GO Terms for Cerebral Neuroblastoma

Biological processes related to Cerebral Neuroblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 8.8 CSF3 IGF2 TP53

Molecular functions related to Cerebral Neuroblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 8.8 CSF3 IGF2 NGF

Sources for Cerebral Neuroblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....