MCID: CRB009
MIFTS: 35

Cerebritis

Categories: Neuronal diseases
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Aliases & Classifications for Cerebritis

MalaCards integrated aliases for Cerebritis:

Name: Cerebritis 11 14 71 75

Classifications:



External Ids:

Disease Ontology 11 DOID:3431
NCIt 49 C27199
UMLS 71 C0742115

Summaries for Cerebritis

Disease Ontology: 11 A brain disease that is characterized by inflammation of the brain tissue occurring as a result of an underlying condition.

MalaCards based summary: Cerebritis is related to intracranial abscess and pleural empyema. An important gene associated with Cerebritis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Immune response IL-23 signaling pathway and NF-kappaB Signaling. Affiliated tissues include brain, bone marrow and globus pallidus.

Wikipedia: 75 Cerebritis is the inflammation of the cerebrum, which performs a number of important functions, such as... more...

Related Diseases for Cerebritis

Diseases related to Cerebritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 937)
# Related Disease Score Top Affiliating Genes
1 intracranial abscess 30.6 CRP CD4
2 pleural empyema 30.0 IL6 CRP CD4 ALB
3 listeria meningitis 30.0 TNF CD8A
4 haemophilus influenzae 29.9 TNF IL1B
5 subacute bacterial endocarditis 29.9 CRP ALB
6 bacterial meningitis 29.9 TNF IL1B CRP
7 myelitis 29.8 TNF IL6 AQP4 APOH
8 rocky mountain spotted fever 29.8 CRP CD4
9 infective endocarditis 29.7 IL6 CRP ALB
10 invasive aspergillosis 29.7 TNF IL6 CRP CD4
11 toxoplasmosis 29.7 TNF IL6 IL1B
12 encephalitis 29.7 TNF IL6 IL1B AQP4
13 pulmonary embolism 29.7 CRP APOH ALB
14 polyarteritis nodosa 29.6 TNF IL6 CRP APOH
15 aspergillosis 29.5 TNF IL6 IL1B
16 listeriosis 29.4 TNF IL6 IL1B CD8A CD4
17 mucormycosis 29.4 TNF IL6 CRP CD8A CD4
18 meningitis 29.4 TNF IL6 IL1B CRP AQP4 ALB
19 pericardial effusion 29.3 TNF IL6 CRP CD4 ALB
20 covid-19 29.3 TNF IL6 IL1B CRP
21 brain edema 29.3 IL6 IL1B CRP AQP4 ALB
22 lyme disease 29.3 TNF IL6 IL1B CRP
23 granulomatosis with polyangiitis 29.3 TNFSF13B TNF CRP CD8A CD4
24 endocarditis 29.2 TNF IL6 CRP APOH ALB
25 mixed connective tissue disease 29.2 TNFSF13B TNF SNRNP70 IL6 APOH
26 diarrhea 29.1 TNF IL6 IL1B ALB
27 autoimmune disease 29.0 TNFSF13B TNF IL6 IL1B CRP AQP4
28 vasculitis 29.0 TNFSF13B TNF IL6 IL1B CRP APOH
29 acquired immunodeficiency syndrome 28.9 TNF IL6 IL1B CRP CD4 ALB
30 typhoid fever 28.9 TNF IL6 IL1B CRP ALB
31 amyloidosis 28.9 TNF IL6 IL1B CRP ALB
32 peritonitis 28.9 TNF IL6 IL1B CRP ALB
33 transverse myelitis 28.9 TNF IL6 CRP CD8A CD4 AQP4
34 common cold 28.8 TNF IL6 IL1B CRP CD8A CD4
35 alcohol use disorder 28.7 TNF IL6 IL1B CRP CD4 ALB
36 intracranial hypertension 28.6 TNF IL6 IL1B CRP AQP4 APOH
37 cellulitis 28.6 TNF IL6 IL1B CRP CD8A CD4
38 aseptic meningitis 28.6 TNF IL6 IL1B CRP CD8A CD4
39 exanthem 28.6 TNF IL6 IL1B CRP CD8A CD4
40 meningoencephalitis 28.6 TNF IL6 IL1B CRP CD8A CD4
41 leukemia, acute myeloid 28.5 TNF IL6 IL1B CD8A CD4 ALB
42 rheumatoid arthritis 28.4 TNFSF13B TNF IL6 IL1B CRP CD4
43 crohn's disease 28.4 TNF IL6 IL1B CRP CD8A CD4
44 immune deficiency disease 28.4 TNFSF13B TNF IL6 IL1B CRP CD8A
45 systemic lupus erythematosus 28.4 TNFSF13B TNF SNRNP70 IL6 IL1B CRP
46 systemic scleroderma 28.3 TNFSF13B TNF SNRNP70 IL6 IL1B CRP
47 asthma 28.3 TNFSF13B TNF IL6 IL1B CRP CD4
48 chickenpox 28.2 TNF IL6 IL1B CRP CD8A CD4
49 nervous system disease 28.1 TNF IL6 IL1B CRP CD8A CD4
50 peripheral nervous system disease 28.1 TNF IL6 IL1B CRP CD8A CD4

Graphical network of the top 20 diseases related to Cerebritis:



Diseases related to Cerebritis

Symptoms & Phenotypes for Cerebritis

Drugs & Therapeutics for Cerebritis

Search Clinical Trials, NIH Clinical Center for Cerebritis

Genetic Tests for Cerebritis

Anatomical Context for Cerebritis

Organs/tissues related to Cerebritis:

MalaCards : Brain, Bone Marrow, Globus Pallidus, Temporal Lobe, Bone, Spinal Cord, Neutrophil

Publications for Cerebritis

Articles related to Cerebritis:

(show top 50) (show all 430)
# Title Authors PMID Year
1
Management of Extensive Central Nervous System Cladophialophora bantiana Infection in a 9-Year-Old Child. 62
36102704 2022
2
Deadly Fungi: Invasive Fungal Rhinosinusitis in the Head and Neck. 62
36178803 2022
3
Plasma Microbial Cell-Free DNA (CF-DNA) Next-Generation Sequencing in Diagnosing Intracranial Abscesses: Pathophysiology and a Scoping Review of the Literature. 62
36148190 2022
4
Varied imaging and clinical presentations of acute bacterial cerebritis. 62
35482173 2022
5
The first case of Streptococcus intermedius brain abscess with hemophagocytic histiocytosis. 62
35850669 2022
6
Investigation of a cluster of Bacillus cereus bacteremia in neonatal care units. 62
34340907 2022
7
Lupus Cerebritis as a Rare Neuropsychiatric Manifestation of Systemic Lupus Erythematosus. 62
35698669 2022
8
Orbital and Sinonasal Complications of Hydrogel Scleral Buckle: A Case Report. 62
35604377 2022
9
Magnetic Resonance Imaging in Coronavirus Disease - 2019 Associated Rhino-Orbital-Cerebral Mucormycosis (CA-ROCM) - Imaging Analysis of 50 Consecutive Patients. 62
34802841 2022
10
Pott's Puffy Tumor Presenting as Pyogenic Meningitis in an Infant. 62
35371577 2022
11
Recrudescent infection after deep brain stimulator reimplantation. 62
35090130 2022
12
A Unique Triad of Invasive Sinusitis, Brain Abscess with Focal Cerebritis, and COVID-19. 62
34702794 2021
13
Different causes and diverse outcomes of extremely rare septic cavernous sinus thrombosis complicated with internal carotid artery stenosis. 62
34615537 2021
14
Safety and Accuracy of Ultrasound-guided Burr Hole Brain Abscess Aspiration. 62
33618413 2021
15
Brain abscess caused by Salmonella Enteritidis following craniotomy for meningioma: A case report and literature review. 62
34448798 2021
16
Seizure after recovery from Covid-19. 62
34568161 2021
17
A Flare of Systemic Lupus Erythematosus Disease After COVID-19 Infection: A Case of Lupus Cerebritis. 62
34350072 2021
18
Neurolisteriosis: The Importance of a Prompt Diagnosis. 62
34458048 2021
19
Systemic Lupus Erythematosus With Multi-Organ Involvement in a Young Female: Lymphadenopathy, Lupus Cerebritis, Lupus Nephritis, and Cardiac Manifestations. 62
34268044 2021
20
Lupus Cerebritis as the Initial Presentation of Systemic Lupus Erythematosus in a Young Female. 62
33959443 2021
21
Magnetic Resonance Imaging in Peripartum Encephalopathy: A Pictorial Review. 62
33927531 2021
22
Cryptococcus Meningoencephalitis With Severe Localizing Neurological Deficits Mimicking a Large Right Middle Cerebral Artery Infarct in a HIV Patient. 62
33959463 2021
23
Systemic lupus erythematosus multiorgan flare with quiescent serologic markers. 62
33653839 2021
24
Hemichorea-Hemiballismus as a Presentation of Cerebritis from Intracranial Toxoplasmosis and Tuberculosis. 62
33552670 2021
25
Rothia mucilaginosa bacteremia, meningitis leading to diffuse cerebritis in an adolescent patient undergoing acute myeloid leukemia chemotherapy causing significant morbidity. 62
34900260 2021
26
Case Report: Ascending Myelo-Encephalitis after a Penetrating Injury to the Foot: An Atypical Case of Neuromelioidosis. 62
33432905 2021
27
Lupus Cerebritis Refractory to Guideline-Directed Therapy: A Case Report. 62
33843326 2021
28
Neuromelioidosis: A Single-Center Experience with Emphasis on Imaging. 62
34316112 2021
29
Acute actinomycotic brain abscess in a patient with rheumatoid arthritis. 62
33210383 2020
30
A Case of Neuroschistosomiasis Presenting as Transverse Myelitis: The Importance of History Taking. 62
33324527 2020
31
Primary Psychiatric Disorder Masking the Diagnosis of Lupus Cerebritis. 62
33376654 2020
32
Rhino-orbital-cerebral mucormycosis (ROCM) and associated cerebritis treated with adjuvant retrobulbar amphotericin B. 62
32551404 2020
33
MRI Spectrum of Haemophilus influenzae Meningoencephalitis in Children. 62
33623260 2020
34
Correction to: Combined microsurgical fluorescence for optimizing resection in refractory empyema and cerebritis. 62
32691195 2020
35
Combined microsurgical fluorescence for optimizing resection in refractory empyema and cerebritis. 62
32601901 2020
36
Brainstem Encephalitis Caused by Listeria monocytogenes. 62
32872638 2020
37
Cerebral abscesses imaging: A practical approach. 62
32757543 2020
38
Aspergillus and Rhizopus Fungal Coinfection in a Patient With Multiple Myeloma. 62
32537269 2020
39
Multiple Intracranial Tuberculomas with an Intra-medullary Spinal Cord Tuberculoma in a Pediatric Patient. 62
32292663 2020
40
Holohemispheric Invasive Aspergillus Granulomatous Cerebritis of the Brain. 62
31562969 2020
41
Listeria Cerebritis with Tumor Necrosis Factor Inhibition. 62
32373374 2020
42
Invasion of Host Cells by Microsporidia. 62
32132983 2020
43
Dual-Use Intraoperative MRI in Glioblastoma Surgery: Results of Resection, Histopathologic Assessment, and Surgical Site Infections. 62
31272122 2019
44
A case report of multiple cerebral abscess formation complicating serogroup B Neisseria meningitidis meningitis. 62
31638913 2019
45
Comparison of CSF and MRI Findings among Neonates and Infants with E coli or Group B Streptococcal Meningitis. 62
31320464 2019
46
Suspected hematologic malignancy complicates lupus cerebritis treatment. 62
30913146 2019
47
Tocilizumab for the management of immune mediated adverse events secondary to PD-1 blockade. 62
29207939 2019
48
The needs for diagnostic imaging in cases of group A streptococcal meningitis in children: a case report and review of the literature. 62
32974559 2019
49
Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits. 62
30610193 2019
50
A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales. 62
31695784 2019

Variations for Cerebritis

Expression for Cerebritis

Search GEO for disease gene expression data for Cerebritis.

Pathways for Cerebritis

Pathways related to Cerebritis according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.46 TNF IL6 IL1B CD4
2 12.43 TNFSF13B TNF IL1B CD8A
3 12.04 AQP4 IL1B IL6 TNF
4
Show member pathways
11.86 IL1B CD8A CD4
5 11.84 TNF IL6 IL1B
6 11.82 TNF IL6 CD8A CD4
7
Show member pathways
11.75 IL6 IL1B CD4
8
Show member pathways
11.73 TNF IL6 IL1B CD4
9 11.66 IL1B IL6 TNF
10 11.63 TNF IL6 CRP
11 11.61 IL6 IL1B CD4
12 11.61 TNFSF13B TNF IL6 IL1B AQP4
13 11.57 CD4 CD8A IL1B TNF
14
Show member pathways
11.56 TNF IL6 IL1B
15 11.55 TNF IL6 IL1B
16
Show member pathways
11.51 IL6 CRP CD8A CD4
17 11.41 TNF IL6 IL1B
18 11.38 TNF IL6 IL1B
19 11.35 TNFSF13B TNF IL6 IL1B
20 11.24 TNF IL6 IL1B
21 11.19 TNF IL6 IL1B
22 11.15 TNF IL6 IL1B
23 11.1 TNF IL6 IL1B
24 10.89 TNF IL6 IL1B CD8A CD4
25 10.88 IL6 IL1B
26 10.86 TNF IL6 CRP
27 10.85 TNF IL1B
28 10.72 TNF IL6 IL1B CD4
29 10.7 IL6 IL1B
30
Show member pathways
10.27 TNF IL6

GO Terms for Cerebritis

Cellular components related to Cerebritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.62 TNFSF13B TNF IL6 IL1B CSTL1 CRP

Biological processes related to Cerebritis according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of interleukin-8 production GO:0032757 10.03 TNF IL6 IL1B
2 defense response to Gram-positive bacterium GO:0050830 10.03 CRP IL1B IL6 TNF
3 positive regulation of T cell proliferation GO:0042102 10.02 TNFSF13B IL6 IL1B
4 immune response GO:0006955 10.02 TNFSF13B TNF IL6 IL1B CD8A CD4
5 response to glucocorticoid GO:0051384 10.01 TNF IL6 AQP4
6 regulation of insulin secretion GO:0050796 10 IL1B IL6 TNF
7 positive regulation of chemokine production GO:0032722 9.89 TNF IL6 IL1B
8 positive regulation of fever generation GO:0031622 9.81 TNF IL1B
9 negative regulation of neurogenesis GO:0050768 9.8 TNF IL6 IL1B
10 sequestering of triglyceride GO:0030730 9.78 TNF IL1B
11 regulation of vascular endothelial growth factor production GO:0010574 9.76 IL6 AQP4
12 positive regulation of glial cell proliferation GO:0060252 9.73 IL1B IL6 TNF
13 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.71 TNF IL1B
14 positive regulation of neuroinflammatory response GO:0150078 9.63 TNF IL6 IL1B
15 negative regulation of lipid storage GO:0010888 9.43 TNF IL6 CRP
16 vascular endothelial growth factor production GO:0010573 9.1 TNF IL6 IL1B

Sources for Cerebritis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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