MCID: CRB040
MIFTS: 31

Cerebrum Cancer

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cerebrum Cancer

MalaCards integrated aliases for Cerebrum Cancer:

Name: Cerebrum Cancer 12 15
Malignant Neoplasm of Cerebrum 74
Neoplasm of Cerebrum 12
Tumor of Cerebrum 12
Cerebral Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:368
ICD9CM 36 191.8
NCIt 51 C4874

Summaries for Cerebrum Cancer

Disease Ontology : 12 A supratentorial cancer that is located in the cerebrum.

MalaCards based summary : Cerebrum Cancer, also known as malignant neoplasm of cerebrum, is related to cerebral ventricle cancer and parietal lobe neoplasm. An important gene associated with Cerebrum Cancer is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain, lung and pineal, and related phenotype is Increased proliferation.

Related Diseases for Cerebrum Cancer

Diseases related to Cerebrum Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)
# Related Disease Score Top Affiliating Genes
1 cerebral ventricle cancer 29.9 ENO2 GFAP KCNJ13 RAD54L RBFOX3 SMARCB1
2 parietal lobe neoplasm 11.1
3 cerebral lymphoma 11.1
4 respiratory system benign neoplasm 10.4 ENO2 SYP
5 bone benign neoplasm 10.4 ENO2 SYP
6 malignant pheochromocytoma 10.4 ENO2 SYP
7 connective tissue benign neoplasm 10.4 ENO2 SYP
8 cranial nerve malignant neoplasm 10.4 ENO2 SYP
9 mucinous ovarian cystadenoma 10.4 ENO2 SYP
10 olfactory neuroblastoma 10.4 ENO2 SYP
11 intraocular retinoblastoma 10.4 ENO2 SYP
12 gastric squamous cell carcinoma 10.4 ENO2 SYP
13 mixed ductal-endocrine carcinoma 10.4 ENO2 SYP
14 carcinoid syndrome 10.4 ENO2 SYP
15 horseshoe kidney 10.4 ENO2 SYP
16 extraskeletal ewing sarcoma 10.4 ENO2 SYP
17 pineoblastoma 10.4 GFAP SYP
18 pilomyxoid astrocytoma 10.4 GFAP SYP
19 binswanger's disease 10.4 GFAP SYP
20 traumatic brain injury 10.4 ENO2 GFAP
21 ileum cancer 10.4 ENO2 GFAP
22 granular cell tumor 10.4 ENO2 GFAP
23 dysgerminoma of ovary 10.4 ENO2 GFAP
24 myxosarcoma 10.4 SYP TP53
25 pulmonary blastoma 10.4 SYP TP53
26 liver angiosarcoma 10.4 ENO2 TP53
27 germ cell and embryonal cancer 10.4 ENO2 TP53
28 necrotizing sialometaplasia 10.4 GFAP TP53
29 carotid body cancer 10.4 ENO2 SYP
30 spinal cord astrocytoma 10.4 GFAP TP53
31 fibrillary astrocytoma 10.4 GFAP TP53
32 chondroid chordoma 10.4 ENO2 SMARCB1
33 malignant sertoli cell tumor 10.4 ENO2 SYP
34 urinary bladder small cell neuroendocrine carcinoma 10.4 ENO2 SYP
35 atypical choroid plexus papilloma 10.4 KCNJ13 SYP
36 auditory system cancer 10.4 ENO2 SYP
37 sinonasal undifferentiated carcinoma 10.4 ENO2 SYP
38 desmoplastic infantile ganglioglioma 10.4 GFAP SYP
39 extraventricular neurocytoma 10.4 GFAP SYP
40 pancreatic somatostatinoma 10.4 ENO2 SYP
41 cutaneous ganglioneuroma 10.4 ENO2 SYP
42 lung combined type small cell carcinoma 10.4 GFAP SYP
43 extrahepatic bile duct adenocarcinoma 10.4 ENO2 SYP
44 small cell carcinoma of the bladder 10.4 ENO2 SYP
45 papillary tumor of the pineal region 10.4 ENO2 SYP
46 epithelial-myoepithelial carcinoma 10.4 SMARCB1 TP53
47 sensory organ benign neoplasm 10.4 ENO2 SYP
48 intracranial cysts 10.4 ENO2 GFAP
49 orbital cancer 10.4 ENO2 SYP
50 middle ear adenoma 10.4 ENO2 SYP

Graphical network of the top 20 diseases related to Cerebrum Cancer:



Diseases related to Cerebrum Cancer

Symptoms & Phenotypes for Cerebrum Cancer

GenomeRNAi Phenotypes related to Cerebrum Cancer according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.8 NF2 SMARCB1 TP53

Drugs & Therapeutics for Cerebrum Cancer

Search Clinical Trials , NIH Clinical Center for Cerebrum Cancer

Genetic Tests for Cerebrum Cancer

Anatomical Context for Cerebrum Cancer

MalaCards organs/tissues related to Cerebrum Cancer:

42
Brain, Lung, Pineal, Kidney, Ovary, Spinal Cord, Cervix

The Foundational Model of Anatomy Ontology organs/tissues related to Cerebrum Cancer:

20
The Cerebrum

Publications for Cerebrum Cancer

Articles related to Cerebrum Cancer:

# Title Authors Year
1
Primitive neuroectodermal tumor of cerebrum with adipose tissue. ( 11175648 )
2001
2
Adipose tissue and smooth muscle in a primitive neuroectodermal tumor of cerebrum. ( 8171973 )
1994

Variations for Cerebrum Cancer

Expression for Cerebrum Cancer

Search GEO for disease gene expression data for Cerebrum Cancer.

Pathways for Cerebrum Cancer

Pathways related to Cerebrum Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 ENO2 GFAP NF2 RBFOX3 SYP
2 11.03 GFAP NES SYP

GO Terms for Cerebrum Cancer

Cellular components related to Cerebrum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 8.8 RELA SMARCB1 TP53

Biological processes related to Cerebrum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.16 RELA TP53
2 determination of adult lifespan GO:0008340 8.96 RAD54L TP53
3 DNA strand renaturation GO:0000733 8.62 RAD54L TP53

Molecular functions related to Cerebrum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 8.8 RELA SMARCB1 TP53

Sources for Cerebrum Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....