MCID: CRV013
MIFTS: 33

Cervical Adenoid Cystic Carcinoma

Categories: Cancer diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Cervical Adenoid Cystic Carcinoma

MalaCards integrated aliases for Cervical Adenoid Cystic Carcinoma:

Name: Cervical Adenoid Cystic Carcinoma 12 58 15 17 71
Adenoid Cystic Carcinoma of the Cervix Uteri 12 58

Classifications:

Orphanet: 58  
Rare gynaecological and obstetric diseases


External Ids:

Disease Ontology 12 DOID:4867
NCIt 50 C6346
SNOMED-CT 67 763064007
ICD10 via Orphanet 33 C53.0 C53.1 C53.8
Orphanet 58 ORPHA213823
UMLS 71 C1332911

Summaries for Cervical Adenoid Cystic Carcinoma

Disease Ontology : 12 A cervix carcinoma that is characterized by its resemblance to adenoid cystic carcinoma of the salivary glands. It shows pseudoglandular, cribriform-like and tubular patterns containing basement membrane-like material. Cytologically, the nuclei are angulated and hyperchromatic, without prominent nucleoli.

MalaCards based summary : Cervical Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of the cervix uteri, is related to basaloid squamous cell carcinoma and adenoid cystic carcinoma, and has symptoms including pain An important gene associated with Cervical Adenoid Cystic Carcinoma is NFIB (Nuclear Factor I B), and among its related pathways/superpathways are C-MYB transcription factor network and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include cervix.

Related Diseases for Cervical Adenoid Cystic Carcinoma

Diseases related to Cervical Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 basaloid squamous cell carcinoma 30.3 KRT7 CDKN2A
2 adenoid cystic carcinoma 29.5 NFIB MYB KRT7 KIT CDKN2A
3 cervix carcinoma 10.3
4 rare tumor 10.2
5 synchronous bilateral breast carcinoma 10.2 NFIB KIT
6 cutaneous adenocystic carcinoma 10.1 NFIB KRT7
7 ceruminous adenocarcinoma 10.1 KRT7 KIT
8 laryngeal small cell carcinoma 10.1 KIT CDKN2A
9 maxillary sinus benign neoplasm 10.1 KIT CDKN2A
10 breast leiomyosarcoma 10.1 KRT7 KIT
11 adenoid basal cell carcinoma 10.1 KRT7 KIT
12 jejunal neoplasm 10.1 KRT7 KIT
13 intratubular embryonal carcinoma 10.1 KRT7 KIT
14 lacrimal gland carcinoma 10.1 NFIB KRT7
15 mucinous stomach adenocarcinoma 10.1 KRT7 KIT
16 lipomatosis, multiple 10.1 NFIB KIT
17 sarcomatous intrahepatic cholangiocarcinoma 10.1 KRT7 KIT
18 liver leiomyosarcoma 10.1 KRT7 KIT
19 lung leiomyosarcoma 10.1 KRT7 KIT
20 bladder leiomyoma 10.1 KRT7 KIT
21 mediastinal cancer 10.1 KRT7 KIT
22 uterus leiomyosarcoma 10.1 KRT7 KIT
23 meckel diverticulum 10.1 KRT7 KIT
24 uterine corpus sarcoma 10.1 KRT7 KIT
25 cribriform carcinoma 10.1 KRT7 KIT
26 tenosynovial giant cell tumor 10.1 KIT CDKN2A
27 gliofibroma 10.1 KIT CDKN2A
28 malignant spindle cell melanoma 10.1 KIT CDKN2A
29 seminal vesicle adenocarcinoma 10.1 KRT7 KIT
30 trachea adenoid cystic carcinoma 10.1 NFIB MYB
31 bladder sarcoma 10.1 KRT7 KIT
32 nodular malignant melanoma 10.1 KIT CDKN2A
33 cervical basaloid squamous cell carcinoma 10.1 KRT7 CDKN2A
34 tracheal cancer 10.1 NFIB MYB
35 kidney benign neoplasm 10.1 KRT7 KIT
36 inverted transitional papilloma 10.1 KRT7 CDKN2A
37 acral lentiginous melanoma 10.1 KIT CDKN2A
38 anal canal paget's disease 10.1 KRT7 CDKN2A
39 atrophic vulva 10.1 KRT7 CDKN2A
40 pleomorphic liposarcoma 10.1 KIT CDKN2A
41 vaginal tubulovillous adenoma 10.1 KRT7 CDKN2A
42 mature teratoma 10.1 KRT7 KIT
43 perivascular epithelioid cell tumor 10.1 KIT CDKN2A
44 ovarian seromucinous carcinoma 10.1 KRT7 CDKN2A
45 pleomorphic carcinoma 10.1 KRT7 KIT
46 papillary squamous carcinoma 10.1 KRT7 CDKN2A
47 plexiform neurofibroma 10.1 KIT CDKN2A
48 neurofibroma 10.1 KIT CDKN2A
49 cervical polyp 10.1
50 cervix uteri carcinoma in situ 10.1

Graphical network of the top 20 diseases related to Cervical Adenoid Cystic Carcinoma:



Diseases related to Cervical Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Cervical Adenoid Cystic Carcinoma

UMLS symptoms related to Cervical Adenoid Cystic Carcinoma:


pain

Drugs & Therapeutics for Cervical Adenoid Cystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Adenoid Cystic Carcinoma

Genetic Tests for Cervical Adenoid Cystic Carcinoma

Anatomical Context for Cervical Adenoid Cystic Carcinoma

MalaCards organs/tissues related to Cervical Adenoid Cystic Carcinoma:

40
Cervix

Publications for Cervical Adenoid Cystic Carcinoma

Articles related to Cervical Adenoid Cystic Carcinoma:

(show all 12)
# Title Authors PMID Year
1
Aquaporins 1, 3 and 5 in Different Tumors, their Expression, Prognosis Value and Role as New Therapeutic Targets. 61
30927206 2020
2
Adenoid basal carcinoma of the uterine cervix: clinicopathologic features of 12 cases with reference to CD117 expression. 61
22123720 2012
3
Cytologic characteristics of adenoid cystic carcinoma of the cervix uteri--case report. 61
20432755 2010
4
[Clinical analysis of 38 patients with cephalic and cervical adenoid cystic carcinoma]. 61
16494039 2005
5
Cervical adenoid cystic carcinoma coexisting with multiple human papillomavirus-associated genital lesions. A common etiology? 61
10352392 1999
6
A case of uterine cervical adenoid cystic carcinoma: immunohistochemical study for basement membrane material. 61
7724157 1995
7
Adenoid cystic carcinoma of the uterine cervix. Cytologic features. 61
2157320 1990
8
Cervical adenoid cystic carcinoma associated with ascites. 61
2996994 1985
9
Adenoid cystic carcinoma of the uterine cervix: ultrastructure, immunofluorescence, and criteria for diagnosis. 61
6176118 1982
10
[Case of adenoid cystic carcinoma of the cervix uteri coexistent with squamous cell carcinoma]. 61
542348 1979
11
Adenoid cystic carcinoma of the cervix uteri: report of six cases and review of the literature. 61
221309 1979
12
Cytologic characteristics of adenoid cystic carcinoma of the cervix uteri. 61
180737 1976

Variations for Cervical Adenoid Cystic Carcinoma

Cosmic variations for Cervical Adenoid Cystic Carcinoma:

9 (show top 50) (show all 1113)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM130988744 ZNF507 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.34C>A p.P12T 19:32352864-32352864 0
2 COSM92762591 ZNF507 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.34C>A p.P12T 19:32352864-32352864 0
3 COSM91852150 ZNF507 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.34C>A p.P12T 19:32352864-32352864 0
4 COSM131674386 WASF2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.15G>T p.T5= 1:27428876-27428876 0
5 COSM143041461 WASF2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.15G>T p.T5= 1:27428876-27428876 0
6 COSM101322987 VWA8 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.4027G>A p.E1343K 13:41689458-41689458 0
7 COSM84505255 VWA5B1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.1486G>A p.V496I 1:20330897-20330897 0
8 COSM98138031 VWA5B1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.1486G>A p.V496I 1:20330897-20330897 0
9 COSM109704473 UNC80 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.305A>G p.Q102R 2:209777264-209777264 0
10 COSM85136788 UNC80 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.305A>G p.Q102R 2:209777264-209777264 0
11 COSM129359315 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
12 COSM130341360 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
13 COSM102087709 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
14 COSM110964542 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
15 COSM84976380 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
16 COSM127629055 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
17 COSM92931863 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
18 COSM92931871 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
19 COSM127629064 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
20 COSM110964552 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
21 COSM84976392 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
22 COSM129851007 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
23 COSM130341375 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.100A>C p.M34L 17:44216663-44216663 0
24 COSM102087702 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
25 COSM129851001 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
26 COSM129359304 UBTF salivary gland,NS,carcinoma,adenoid cystic carcinoma c.106A>T p.N36Y 17:44216657-44216657 0
27 COSM146105519 TXNRD3 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.247A>G p.K83E 3:126647293-126647293 0
28 COSM129553208 TXNRD3 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.247A>G p.K83E 3:126647293-126647293 0
29 COSM147490242 TXNRD3 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.247A>G p.K83E 3:126647293-126647293 0
30 COSM126343353 TXNRD3 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.247A>G p.K83E 3:126647293-126647293 0
31 COSM148982261 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
32 COSM151513835 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
33 COSM102618829 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
34 COSM87028709 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
35 COSM101181362 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2255C>T p.A752V 16:2074246-2074246 0
36 COSM151371079 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
37 COSM147692833 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
38 COSM136618137 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2435C>T p.A812V 16:2074246-2074246 0
39 COSM150576172 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
40 COSM149802491 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
41 COSM150314621 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
42 COSM110103993 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2291C>T p.A764V 16:2074246-2074246 0
43 COSM90404312 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
44 COSM151748035 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
45 COSM150355398 TSC2 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2402C>T p.A801V 16:2074246-2074246 0
46 COSM150677194 TSC1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.3265G>T p.E1089* 9:132896450-132896450 0
47 COSM147982976 TSC1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.3277G>T p.E1093* 9:132896450-132896450 0
48 COSM151333958 TSC1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2684T>A p.V895D 9:132897552-132897552 0
49 COSM148034383 TSC1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.2666T>A p.V889D 9:132897552-132897552 0
50 COSM148034268 TSC1 salivary gland,NS,carcinoma,adenoid cystic carcinoma c.3262G>T p.E1088* 9:132896450-132896450 0

Expression for Cervical Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Cervical Adenoid Cystic Carcinoma.

Pathways for Cervical Adenoid Cystic Carcinoma

Pathways related to Cervical Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 MYB KIT
2 10.82 KIT CD1C
3 10.44 NFIB MYB

GO Terms for Cervical Adenoid Cystic Carcinoma

Biological processes related to Cervical Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 somatic stem cell division GO:0048103 8.62 KIT CDKN2A

Sources for Cervical Adenoid Cystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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