MCID: CRV014
MIFTS: 19

Cervical Adenoma Malignum

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Adenoma Malignum

MalaCards integrated aliases for Cervical Adenoma Malignum:

Name: Cervical Adenoma Malignum 12 15
Cervical Mucinous Adenocarcinoma, Minimal Deviation Variant 72

Classifications:



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Disease Ontology 12 DOID:6627
NCIt 50 C40206
UMLS 72 C1516423

Summaries for Cervical Adenoma Malignum

Disease Ontology : 12 A cervical mucinous adenocarcinoma that is well differentiated, consisting of an endocervical glandular hyperplasia of lobular architecture resembling glands but with the characteristics of adenocarcinoma.

MalaCards based summary : Cervical Adenoma Malignum, also known as cervical mucinous adenocarcinoma, minimal deviation variant, is related to peutz-jeghers syndrome and adenoma. An important gene associated with Cervical Adenoma Malignum is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways is Cytoskeletal Signaling.

Related Diseases for Cervical Adenoma Malignum

Diseases related to Cervical Adenoma Malignum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Related Disease Score Top Affiliating Genes
1 peutz-jeghers syndrome 10.4
2 adenoma 10.4
3 ovarian sex cord tumor with annular tubules 10.4
4 mucinous adenocarcinoma 10.3
5 appendix adenocarcinoma 10.3
6 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.3 STK11 HMGA2
7 conventional leiomyosarcoma 10.3 HMGA2 CALD1
8 angiomyoma 10.2 HMGA2 CALD1
9 well-differentiated liposarcoma 10.2 KRT7 HMGA2
10 lipoadenoma 10.2 KRT7 HMGA2
11 thymus lipoma 10.2 KRT7 HMGA2
12 smooth muscle tumor 10.2 MME HMGA2
13 epithelial-myoepithelial carcinoma 10.2 KRT7 HMGA2
14 immune system organ benign neoplasm 10.1 KRT7 HMGA2
15 pulmonary hemosiderosis 10.1 KRT7 HMGA2
16 papillary hidradenoma 10.1 STK11 MME
17 mixed endometrial stromal and smooth muscle tumor 10.1 MME CALD1
18 breast myofibroblastoma 10.1 MME CALD1
19 balloon cell malignant melanoma 10.1 MME KRT7
20 lung combined type small cell carcinoma 10.1 MME CALD1
21 clear cell papillary renal cell carcinoma 10.1 MME KRT7
22 malignant leydig cell tumor 10.1 MME KRT7
23 adenomyoma 10.0 MME KRT7
24 bladder lymphoma 10.0 MME KRT7
25 kidney benign neoplasm 10.0 MME KRT7
26 mucinous tubular and spindle renal cell carcinoma 10.0 MME KRT7
27 breast myoepithelial neoplasm 10.0 MME KRT7
28 breast adenomyoepithelioma 10.0 MME KRT7
29 endometrial stromal nodule 10.0 MME CALD1
30 cystadenofibroma 10.0 MME KRT7
31 infiltrative basal cell carcinoma 10.0 MME KRT7
32 eccrine sweat gland neoplasm 10.0 MME KRT7
33 large cell carcinoma 10.0 STK11 KRT7
34 sarcomatoid squamous cell skin carcinoma 10.0 MME CALD1
35 breast fibroadenoma 10.0 MME HMGA2
36 collecting duct carcinoma 10.0 MME KRT7
37 cell type benign neoplasm 10.0 KRT7 HMGA2
38 pancreatic mucinous cystadenoma 10.0 MME KRT7
39 cystadenoma 10.0 MME KRT7
40 renal-hepatic-pancreatic dysplasia 9.9 KRT7 CALD1
41 mixed cell type cancer 9.9 MME KRT7
42 renal oncocytoma 9.9 MME KRT7
43 oncocytoma 9.9 MME KRT7
44 ovarian brenner tumor 9.9 MME KRT7
45 sarcoma, synovial 9.9 KRT7 HMGA2
46 chromophobe renal cell carcinoma 9.8 MME KRT7
47 carcinosarcoma 9.7 MME KRT7
48 nephrogenic adenofibroma 9.6 MME KRT7 CALD1
49 ileum cancer 9.6 MME KRT7 CALD1
50 renal cell carcinoma, papillary, 1 9.6 MME KRT7

Graphical network of the top 20 diseases related to Cervical Adenoma Malignum:



Diseases related to Cervical Adenoma Malignum

Symptoms & Phenotypes for Cervical Adenoma Malignum

Drugs & Therapeutics for Cervical Adenoma Malignum

Search Clinical Trials , NIH Clinical Center for Cervical Adenoma Malignum

Genetic Tests for Cervical Adenoma Malignum

Anatomical Context for Cervical Adenoma Malignum

Publications for Cervical Adenoma Malignum

Articles related to Cervical Adenoma Malignum:

# Title Authors PMID Year
1
Do hereditary syndrome-related gynecologic cancers have any specific features? 38
26337050 2015
2
[Peutz-Jeghers syndrome complicated by cervical adenoma malignum and ovarian sex cord tumor with annular tubules: report of a case]. 38
17374267 2006
3
Recent advances in immunohistochemistry in gynaecological pathology. 38
11943015 2002
4
Disseminated cervical adenoma malignum and bilateral ovarian sex cord tumors with annular tubules associated with Peutz-Jeghers syndrome. 38
8188091 1994
5
Peutz-Jeghers syndrome with ovarian sex cord tumor with annular tubules and cervical adenoma malignum. 38
1612512 1992
6
Peutz-Jeghers syndrome with ovarian sex cord tumor with annular tubules and cervical adenoma malignum. 38
1916514 1991

Variations for Cervical Adenoma Malignum

Expression for Cervical Adenoma Malignum

Search GEO for disease gene expression data for Cervical Adenoma Malignum.

Pathways for Cervical Adenoma Malignum

Pathways related to Cervical Adenoma Malignum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.29 RAB8A KRT7 CALD1

GO Terms for Cervical Adenoma Malignum

Cellular components related to Cervical Adenoma Malignum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 synaptic vesicle GO:0008021 8.62 RAB8A MME

Biological processes related to Cervical Adenoma Malignum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axonogenesis GO:0007409 8.96 STK11 RAB8A
2 cellular response to UV-B GO:0071493 8.62 STK11 MME

Sources for Cervical Adenoma Malignum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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