MCID: CRV028
MIFTS: 33

Cervical Adenosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Adenosarcoma

MalaCards integrated aliases for Cervical Adenosarcoma:

Name: Cervical Adenosarcoma 12 15 74
Cervical Muellerian Adenosarcoma 12
Cervical Mullerian Adenosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4111
NCIt 51 C40229
UMLS 74 C1516426

Summaries for Cervical Adenosarcoma

Disease Ontology : 12 A cervical carcinosarcoma that is located in the cervix.

MalaCards based summary : Cervical Adenosarcoma, also known as cervical muellerian adenosarcoma, is related to adenosarcoma and adenosarcoma of the cervix uteri. An important gene associated with Cervical Adenosarcoma is GP6 (Glycoprotein VI Platelet), and among its related pathways/superpathways are Cell cycle Role of SCF complex in cell cycle regulation and Formation of Fibrin Clot (Clotting Cascade). The drugs Paclitaxel and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include breast, cervix and ovary.

Related Diseases for Cervical Adenosarcoma

Diseases related to Cervical Adenosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 adenosarcoma 30.6 ESR1 PGR
2 adenosarcoma of the cervix uteri 11.4
3 inverted follicular keratosis 10.1 GP5 GP6
4 cervix uteri carcinoma in situ 10.1 GP5 GP6
5 uterus carcinoma in situ 10.1 GP5 GP6
6 herpangina 10.1 GP5 GP6
7 focal epithelial hyperplasia 10.1 GP5 GP6
8 cervix disease 10.0 GP5 GP6
9 gray platelet syndrome 10.0 GP5 GP6
10 vestibular gland benign neoplasm 9.9 ESR1 PGR
11 bartholin's gland adenoma 9.9 ESR1 PGR
12 vulvar syringoma 9.9 ESR1 PGR
13 lung leiomyoma 9.9 ESR1 PGR
14 leiomyoma 9.9 ESR1 PGR
15 myoma 9.9 ESR1 PGR
16 glassy cell carcinoma of the cervix 9.9 ESR1 PGR
17 vulvar benign neoplasm 9.9 ESR1 PGR
18 trigonitis 9.9 ESR1 PGR
19 vulvar leiomyoma 9.9 ESR1 PGR
20 predominantly cortical thymoma 9.9 ESR1 PGR
21 breast medullary carcinoma 9.9 ESR1 PGR
22 breast scirrhous carcinoma 9.9 ESR1 PGR
23 bartholin's gland benign neoplasm 9.9 ESR1 PGR
24 oncocytic breast carcinoma 9.9 ESR1 PGR
25 progesterone-receptor positive breast cancer 9.9 ESR1 PGR
26 progesterone resistance 9.9 ESR1 PGR
27 endometrial squamous cell carcinoma 9.9 ESR1 PGR
28 cribriform carcinoma 9.9 ESR1 PGR
29 endometrial mucinous adenocarcinoma 9.9 ESR1 PGR
30 adenoid basal cell carcinoma 9.9 ESR1 PGR
31 apocrine adenocarcinoma 9.9 ESR1 PGR
32 peritoneal benign neoplasm 9.9 ESR1 PGR
33 gender identity disorder 9.9 ESR1 PGR
34 deep angioma 9.9 ESR1 PGR
35 diffuse peritoneal leiomyomatosis 9.9 ESR1 PGR
36 leiomyomatosis 9.9 ESR1 PGR
37 synchronous bilateral breast carcinoma 9.9 ESR1 PGR
38 breast adenoid cystic carcinoma 9.9 ESR1 PGR
39 female reproductive endometrioid cancer 9.9 ESR1 PGR
40 estrogen excess 9.9 ESR1 PGR
41 intramuscular hemangioma 9.9 ESR1 PGR
42 glycogen-rich clear cell breast carcinoma 9.9 ESR1 PGR
43 mammographic density 9.9 ESR1 PGR
44 retinitis pigmentosa 47 9.9 ESR1 PGR
45 inflammatory breast carcinoma 9.9 ESR1 PGR
46 retinitis pigmentosa 20 9.9 ESR1 PGR
47 luminal breast carcinoma 9.9 ESR1 PGR
48 endometriosis of ovary 9.9 ESR1 PGR
49 endometriosis 9.9 ESR1 PGR
50 breast benign neoplasm 9.9 ESR1 PGR

Graphical network of the top 20 diseases related to Cervical Adenosarcoma:



Diseases related to Cervical Adenosarcoma

Symptoms & Phenotypes for Cervical Adenosarcoma

Drugs & Therapeutics for Cervical Adenosarcoma

Drugs for Cervical Adenosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
2
Bevacizumab Approved, Investigational Phase 1 216974-75-3
3 Antineoplastic Agents, Phytogenic Phase 1
4 Angiogenesis Modulating Agents Phase 1
5 Antibodies Phase 1
6 Immunoglobulin G Phase 1
7 Antibodies, Monoclonal Phase 1
8 Albumin-Bound Paclitaxel Phase 1
9 Antineoplastic Agents, Immunological Phase 1
10 Antimitotic Agents Phase 1
11 Endothelial Growth Factors Phase 1
12 Immunologic Factors Phase 1
13 Angiogenesis Inhibitors Phase 1
14 Mitogens Phase 1
15 Immunoglobulins Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery or Gynecological Cancers Suspended NCT02020707 Phase 1 Paclitaxel Albumin-Stabilized Nanoparticle Formulation

Search NIH Clinical Center for Cervical Adenosarcoma

Genetic Tests for Cervical Adenosarcoma

Anatomical Context for Cervical Adenosarcoma

MalaCards organs/tissues related to Cervical Adenosarcoma:

42
Breast, Cervix, Ovary, Endothelial, Lung, Bone, Smooth Muscle

The Foundational Model of Anatomy Ontology organs/tissues related to Cervical Adenosarcoma:

20
The Cervix

Publications for Cervical Adenosarcoma

Articles related to Cervical Adenosarcoma:

# Title Authors Year
1
Clinical management of uterine cervical mullerian adenosarcoma: A clinicopathological study of six cases and review of the literature. ( 30122564 )
2018
2
Case Report of Successful Childbearing after Conservative Surgery for Cervical Mullerian Adenosarcoma. ( 28154764 )
2017
3
Cervical Mullerian adenosarcoma with heterologous sarcomatous overgrowth: a fourth case and review of literature. ( 21663687 )
2011
4
Cervical mullerian adenosarcoma: case report. ( 6299743 )
1982

Variations for Cervical Adenosarcoma

Expression for Cervical Adenosarcoma

Search GEO for disease gene expression data for Cervical Adenosarcoma.

Pathways for Cervical Adenosarcoma

GO Terms for Cervical Adenosarcoma

Biological processes related to Cervical Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription initiation from RNA polymerase II promoter GO:0006367 9.26 ESR1 PGR
2 platelet activation GO:0030168 9.16 GP5 GP6
3 hemostasis GO:0007599 8.96 GP5 GP6
4 steroid hormone mediated signaling pathway GO:0043401 8.62 ESR1 PGR

Molecular functions related to Cervical Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.26 ESR1 PGR
2 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
3 nuclear receptor activity GO:0004879 8.96 ESR1 PGR
4 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Cervical Adenosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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