MCID: CRV028
MIFTS: 29

Cervical Adenosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Adenosarcoma

MalaCards integrated aliases for Cervical Adenosarcoma:

Name: Cervical Adenosarcoma 12 15 73
Cervical Muellerian Adenosarcoma 12
Cervical Mullerian Adenosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4111
NCIt 50 C40229
UMLS 73 C1516426

Summaries for Cervical Adenosarcoma

Disease Ontology : 12 A cervical carcinosarcoma that is located in the cervix.

MalaCards based summary : Cervical Adenosarcoma, also known as cervical muellerian adenosarcoma, is related to adenosarcoma of the cervix uteri and adenosarcoma. An important gene associated with Cervical Adenosarcoma is GP6 (Glycoprotein VI Platelet), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. The drugs Paclitaxel and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include the cervix, cervix and endothelial.

Related Diseases for Cervical Adenosarcoma

Diseases related to Cervical Adenosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 adenosarcoma of the cervix uteri 11.4
2 adenosarcoma 10.5
3 inverted follicular keratosis 10.0 GP5 GP6
4 cervix uteri carcinoma in situ 10.0 GP5 GP6
5 uterus carcinoma in situ 10.0 GP5 GP6
6 herpangina 10.0 GP5 GP6
7 focal epithelial hyperplasia 9.9 GP5 GP6
8 cervix disease 9.9 GP5 GP6
9 gray platelet syndrome 9.9 GP5 GP6
10 cervical clear cell adenocarcinoma 9.9 GP5 PGR
11 endometritis 9.8 PGR SELE
12 female reproductive system disease 9.8 GP5 PGR
13 uterine anomalies 9.7 GP5 GP6 PGR
14 reproductive system disease 9.7 GP5 PGR
15 cervical carcinosarcoma 9.5 GP5 GP6 PGR SELE

Graphical network of the top 20 diseases related to Cervical Adenosarcoma:



Diseases related to Cervical Adenosarcoma

Symptoms & Phenotypes for Cervical Adenosarcoma

Drugs & Therapeutics for Cervical Adenosarcoma

Drugs for Cervical Adenosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
2
Bevacizumab Approved, Investigational Phase 1 216974-75-3
3 Antibodies Phase 1
4 Immunoglobulins Phase 1
5 Immunologic Factors Phase 1
6 Antineoplastic Agents, Phytogenic Phase 1
7 Angiogenesis Modulating Agents Phase 1
8 Antimitotic Agents Phase 1
9 Endothelial Growth Factors Phase 1
10 Immunoglobulin G Phase 1
11 Antibodies, Monoclonal Phase 1
12 Angiogenesis Inhibitors Phase 1
13 Albumin-Bound Paclitaxel Phase 1
14 Mitogens Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery or Gynecological Cancers Recruiting NCT02020707 Phase 1 Paclitaxel Albumin-Stabilized Nanoparticle Formulation

Search NIH Clinical Center for Cervical Adenosarcoma

Genetic Tests for Cervical Adenosarcoma

Anatomical Context for Cervical Adenosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Cervical Adenosarcoma:

19
The Cervix

MalaCards organs/tissues related to Cervical Adenosarcoma:

41
Cervix, Endothelial, Uterus

Publications for Cervical Adenosarcoma

Articles related to Cervical Adenosarcoma:

# Title Authors Year
1
Clinical management of uterine cervical mullerian adenosarcoma: A clinicopathological study of six cases and review of the literature. ( 30122564 )
2018
2
Case Report of Successful Childbearing after Conservative Surgery for Cervical Mullerian Adenosarcoma. ( 28154764 )
2017
3
Cervical Mullerian adenosarcoma with heterologous sarcomatous overgrowth: a fourth case and review of literature. ( 21663687 )
2011
4
Cervical mullerian adenosarcoma: case report. ( 6299743 )
1982

Variations for Cervical Adenosarcoma

Expression for Cervical Adenosarcoma

Search GEO for disease gene expression data for Cervical Adenosarcoma.

Pathways for Cervical Adenosarcoma

GO Terms for Cervical Adenosarcoma

Cellular components related to Cervical Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 8.8 GP5 GP6 SELE

Biological processes related to Cervical Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.26 GP6 SELE
2 blood coagulation GO:0007596 9.16 GP5 GP6
3 platelet activation GO:0030168 8.96 GP5 GP6
4 hemostasis GO:0007599 8.62 GP5 GP6

Molecular functions related to Cervical Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.62 GP6 SELE

Sources for Cervical Adenosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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