MCID: CRV043
MIFTS: 46

Cervical Dystonia

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Cervical Dystonia

MalaCards integrated aliases for Cervical Dystonia:

Name: Cervical Dystonia 12 53 37 15
Spasmodic Torticollis 12 76 53

Classifications:



External Ids:

Disease Ontology 12 DOID:0050840
KEGG 37 H01608
ICD10 33 G24.3

Summaries for Cervical Dystonia

NIH Rare Diseases : 53 Cervical dystoniais a neurological condition characterized by excessive pulling of the muscles of the neck and shoulder resulting in abnormal movements of the head (dystonia). Most commonly, the head turns to one side or the other. Tilting sideways, or to the back or front may also occur. The turning or tilting movements may be accompanied by shaking movement (tremor) and/or soreness of the muscles of the neck and shoulders. Cervical dystonia can occur at any age, but most cases occur in middle age. It often begins slowly and usually reaches a plateau over a few months or years. The cause of cervical dystonia is often unknown. In some cases there is a family history. Several genes have been associated with cervical dystonia, including GNAL, THAP1, CIZ1, and ANO3. Other cases may be linked to an underlying disease (e.g. Parkinson disease), neck trauma, or certain medications. Treatment may include local injections of botulinum toxin, pain medications, benzodiazepines (anti-anxiety medications), anticholinergics, physical therapy, or surgery.

MalaCards based summary : Cervical Dystonia, also known as spasmodic torticollis, is related to dystonia 24 and dystonia 11, myoclonic. An important gene associated with Cervical Dystonia is CIZ1 (CDKN1A Interacting Zinc Finger Protein 1), and among its related pathways/superpathways are ICos-ICosL Pathway in T-Helper Cell and Tuberculosis. The drugs Acetylcholine and Acetylcholine Release Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include brain, globus pallidus and subthalamic nucleus, and related phenotypes are behavior/neurological and mortality/aging

Disease Ontology : 12 A focal dystonia that is characterized by simultaneous contraction of the agonist and antagonist muscles that control the position of the head contracting during dystonic movement which causes the neck to involuntarily turn to the left, right, upwards, and/or downwards.

Wikipedia : 76 Spasmodic torticollis is an extremely painful chronic neurological movement disorder causing the neck to... more...

Related Diseases for Cervical Dystonia

Diseases related to Cervical Dystonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 dystonia 24 31.8 THAP1 TOR1A
2 dystonia 11, myoclonic 31.4 CAMP GCH1 THAP1 TOR1A
3 dystonia 31.1 CIZ1 DRD5 GCH1 GNAL THAP1 TOR1A
4 torticollis 30.6 CIZ1 TOR1A
5 spasmodic dysphonia 30.0 THAP1 TOR1A
6 blepharospasm 29.8 CAMP DRD5 GCH1 GNAL THAP1 TOR1A
7 focal hand dystonia 29.3 CAMP DRD5 THAP1 TOR1A
8 spasmodic dystonia 29.2 CAMP GNAL THAP1 TOR1A
9 lymphedema, hereditary, ii 29.0 CAMP DRD5 GCH1 THAP1 TOR1A
10 focal dystonia 28.4 CAMP CDIP1 CIZ1 DRD5 GNAL THAP1
11 dystonia 23 11.7
12 torticollis, familial 11.7
13 leukoencephalopathy with dystonia and motor neuropathy 11.5
14 x-linked dystonia-parkinsonism/lubag 11.2
15 dystonia 4, torsion, autosomal dominant 11.1
16 dystonia 7, torsion 11.1
17 torsion dystonia 4 11.1
18 adolescent-onset dystonia of mixed type 11.1
19 benign paroxysmal torticollis of infancy 10.4
20 tremor 10.4
21 alexithymia 10.2
22 social phobia 10.2
23 neuropathy 10.2
24 autosomal dominant cerebellar ataxia 10.2
25 essential tremor 10.2
26 achalasia, familial esophageal 10.2 HLA-DQA1 HLA-DQB1
27 beryllium disease 10.1 HLA-DQA1 HLA-DQB1
28 dysphagia 10.1
29 idiopathic bronchiectasis 10.1 HLA-DQA1 HLA-DQB1
30 congenital toxoplasmosis 10.1 HLA-DQA1 HLA-DQB1
31 acute disseminated encephalomyelitis 10.1 HLA-DQA1 HLA-DQB1
32 oligoarticular juvenile idiopathic arthritis 10.1 HLA-DQA1 HLA-DQB1
33 endometritis 10.1 HLA-DQA1 HLA-DQB1
34 immunoglobulin alpha deficiency 10.1 HLA-DQB1 TOR1A
35 headache 10.1
36 hemifacial spasm 10.1
37 tardive dyskinesia 10.1
38 anxiety 10.1
39 thrombosis 10.1
40 thoracic outlet syndrome 10.1
41 neurotic disorder 10.1
42 acquired immunodeficiency syndrome 10.1
43 narcolepsy 10.1
44 athetosis 10.1
45 cytomegalovirus infection 10.1
46 head injury 10.1
47 thiamine metabolism dysfunction syndrome 2 10.0 GCH1 TOR1A
48 kleine-levin hibernation syndrome 10.0 HLA-DQB1 TOR1A
49 multifocal dystonia 10.0 CAMP TOR1A
50 spinocerebellar ataxia 2 10.0

Graphical network of the top 20 diseases related to Cervical Dystonia:



Diseases related to Cervical Dystonia

Symptoms & Phenotypes for Cervical Dystonia

MGI Mouse Phenotypes related to Cervical Dystonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.56 BDNF CIZ1 DRD5 GNAL HLA-DQB1 NALCN
2 mortality/aging MP:0010768 9.28 BDNF CAMP DRD5 GCH1 GNAL HLA-DQB1

Drugs & Therapeutics for Cervical Dystonia

Drugs for Cervical Dystonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 61)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-84-3 187
2 Acetylcholine Release Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
3 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
4 Cholinergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
5 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
6 abobotulinumtoxinA Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
7 Botulinum Toxins, Type A Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
8 onabotulinumtoxinA Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
9 Neuromuscular Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
10 Botulinum Toxins Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
11 rimabotulinumtoxinB Phase 4,Phase 2
12 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2
13 incobotulinumtoxinA Phase 4,Phase 3,Phase 2
14
Propranolol Approved, Investigational Phase 2, Phase 3 525-66-6 4946
15 Vasodilator Agents Phase 2, Phase 3
16 Antihypertensive Agents Phase 2, Phase 3
17 Anti-Arrhythmia Agents Phase 2, Phase 3
18 Adrenergic beta-Antagonists Phase 2, Phase 3
19 Adrenergic Antagonists Phase 2, Phase 3
20 Adrenergic Agents Phase 2, Phase 3
21
Dronabinol Approved, Illicit Phase 2 1972-08-3 16078
22
Etanercept Approved, Investigational Phase 1, Phase 2 185243-69-0
23
Amlodipine Approved Phase 2 88150-42-9 2162
24 Etiracetam Investigational Phase 2 33996-58-6
25 Analgesics, Non-Narcotic Phase 2,Phase 1
26 Psychotropic Drugs Phase 2
27 Hormones Phase 2
28 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
29 Cannabinoid Receptor Agonists Phase 2
30 Analgesics Phase 2,Phase 1
31 Hallucinogens Phase 2
32 Hormone Antagonists Phase 2
33 Immunosuppressive Agents Phase 1, Phase 2
34 Anti-Inflammatory Agents, Non-Steroidal Phase 1, Phase 2
35 Anti-Inflammatory Agents Phase 1, Phase 2,Not Applicable
36 Antirheumatic Agents Phase 1, Phase 2
37 Immunologic Factors Phase 1, Phase 2
38 Autoantibodies Phase 1, Phase 2
39 Gastrointestinal Agents Phase 1, Phase 2
40 Calcium, Dietary Phase 2
41 calcium channel blockers Phase 2
42 Nootropic Agents Phase 2
43 Anticonvulsants Phase 2
44
Trihexyphenidyl Approved 144-11-6, 58947-95-8 5572
45
Triamcinolone Approved, Vet_approved Not Applicable 124-94-7 31307
46
Methylprednisolone hemisuccinate Approved Not Applicable 2921-57-5
47
Prednisolone Approved, Vet_approved Not Applicable 50-24-8 5755
48
Cortisone acetate Approved, Investigational Not Applicable 1950-04-4, 50-04-4 5745
49
Methylprednisolone Approved, Vet_approved Not Applicable 83-43-2 6741
50
Prednisolone phosphate Approved, Vet_approved Not Applicable 302-25-0

Interventional clinical trials:

(show top 50) (show all 106)
# Name Status NCT ID Phase Drugs
1 The Impact of Botulinum Toxin Treatment in Quality of Life of Cervical Dystonia Patients Unknown status NCT01664013 Phase 4 Nuronox
2 Botox for Cervical Dystonia Following EMG Mapping Completed NCT00773253 Phase 4 Botulinum toxin A
3 A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia Completed NCT00950664 Phase 4 Dysport® (abobotulinumtoxinA);Botox® (onabotulinumtoxinA)
4 An Open Label Safety and Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) Injectable Solution in Patients With Cervical Dystonia Completed NCT00702754 Phase 4
5 Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With Cervical Dystonia Flex Completed NCT01486264 Phase 4
6 Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia Completed NCT00541905 Phase 4 NT 201
7 Efficacy and Safety of Meditoxin® Injection for Cervical Dystonia in Adults With Cerebral Palsy Completed NCT01860196 Phase 4 Meditoxin;Normal saline
8 Neurotoxin and Physical Therapy Completed NCT02177617 Phase 4 Botox injection
9 Effect of Botulinum Toxin Type A on Swallowing in Patients With Cervical Dystonia Completed NCT01384214 Phase 4
10 Comparison of Efficacy and Safety of Two Different Types of Botulinum Toxin Type A in Moderate to Severe Cervical Dystonia Completed NCT00528541 Phase 4
11 Functional Effects of Botox on the Brain Using MRS and fMRI Completed NCT03373162 Phase 4 onabotulinumtoxinA
12 OnabotulinumtoxinA in the Management of Psychogenic Dystonia Completed NCT02618889 Phase 4
13 Frontalis Botulinum Toxin Not yet recruiting NCT03186001 Phase 4 Abobotulinum toxin A
14 Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia Terminated NCT00432341 Phase 4
15 Evaluation of Botulinum Toxin Injection Efficacy in the Treatment of Head Essential Tremor Unknown status NCT02555982 Phase 3 BOTOX ® 200 Unités;Placebo
16 Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia Completed NCT00447772 Phase 3 Botulinum type A toxin (Dysport®)
17 Efficacy and Safety of DYSPORT® Using 2mL Dilution in Adults With Cervical Dystonia. Completed NCT01753310 Phase 3 Dysport®;Placebo
18 Study Comparing Short Term Efficacy of Dysport® and Dysport RU® to Placebo, and to Assess Efficacy and Safety of Dysport RU® of Subjects With Cervical Dystonia Completed NCT01261611 Phase 3 Botulinum type A toxin (Dysport RU®);Botulinum type A toxin (Dysport®);Placebo
19 Double-blind, Multicenter Study to Assess the Efficacy of Bilateral Pallidal Stimulation in Patients With Medically Refractory Primary Cervical Dystonia Completed NCT00148889 Phase 3
20 Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia Completed NCT01753336 Phase 3 Dysport®
21 Open-label Extension Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia Completed NCT00288509 Phase 3 abobotulinumtoxinA (Dysport) 250-1000 units
22 Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia Completed NCT00257660 Phase 3 Botulinum type A toxin (Dysport®);Placebo
23 IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia Completed NCT00407030 Phase 3 incobotulinumtoxinA (Xeomin) (240 Units);incobotulinumtoxinA (Xeomin) (120 Units);Placebo
24 Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia Completed NCT02604186 Phase 2, Phase 3
25 Addressing Involuntary Movements in Tardive Dyskinesia Completed NCT02291861 Phase 3 SD-809;Placebo
26 Aim to Reduce Movements in Tardive Dyskinesia Completed NCT02195700 Phase 2, Phase 3 SD-809;Placebo
27 Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1) Recruiting NCT03608397 Phase 3
28 Meditoxin® Treatment in Patients With Cervical Dystonia Recruiting NCT03232320 Phase 3 Meditoxin;Placebo
29 Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-OLS) Recruiting NCT03617367 Phase 3
30 Safety and Efficacy of Propranolol in the Treatment of Tardive Dyskinesia Recruiting NCT03254186 Phase 2, Phase 3 Propranolol Hydrochloride;Placebo Oral Tablet
31 Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia Not yet recruiting NCT03805152 Phase 3 Neuronox(R);Dysport (R)
32 ASIS for Botox in Cervical Dystonia Unknown status NCT02074293 Phase 1, Phase 2 Gadolinium;Gadolinium;Gadolinium;Efficacy of Botox intramuscularly at Week 6;Efficacy of Botox intramuscularly at Week 12;Efficacy of Botox intramuscularly at Week 18;Efficacy of Botox intramuscularly at Week 24;Efficacy of Botox intramuscularly at Week 30;Efficacy of Botox subdermally at Week 6;Efficacy of Botox subdermally at Week 12;Efficacy of Botox subdermally at Week 18;Efficacy of Botox subdermally at Week 24;Efficacy of Botox subdermally at Week 30;Adverse Reactions of Botox intramuscularly;Adverse Reactions of Botox subdermally
33 Efficacy of Dronabinol for the Treatment of Cervical Dystonia Unknown status NCT00418925 Phase 2 Dronabinol
34 Study of the Treatment of Tendinopathy Unruptured of Rotator Cuff by Intramuscular Injection of Botulinum Toxin Unknown status NCT02867787 Phase 2 Botox arm
35 ASIS for Enbrel in Plaque Psoriasis Unknown status NCT02112097 Phase 1, Phase 2 Gadolinium;Gadolinium;Gadolinium;Efficacy of Enbrel subcutaneously at Week 12;Efficacy of Enbrel subcutaneously at Week 24;Efficacy of Enbrel subcutaneously at Week 36;Efficacy of Enbrel subdermally at Week 12;Efficacy of Enbrel subdermally at Week 24;Efficacy of Enbrel subdermally at Week 36;PASI 75 n(%) subcutaneously at Week 12;PASI 75 n(%) subcutaneously at Week 24;PASI 75 n(%) subcutaneously at Week 36;PASI 75 n(%) subdermally at Week 12;PASI 75 n(%) subdermally at Week 24;PASI 75 n(%) subdermally at Week 36;Adverse Reactions of Enbrel subcutaneously;Adverse Reactions of Enbrel subdermally at Week 36;Gadolinium;Gadolinium;Gadolinium
36 Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia Completed NCT00564681 Phase 2 Normal Saline
37 Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain Completed NCT00178945 Phase 1, Phase 2 Botulinum Toxin Type A
38 Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis Completed NCT00165776 Phase 2 BOTULINUM TOXIN TYPE B
39 Dose-escalating Safety and Preliminary Efficacy of DaxibotulinumtoxinA for Injection in Cervical Dystonia Completed NCT02706795 Phase 2
40 Study for Determine the Safety and Efficacy of Clostridium Botulinum Toxin Type A in Subjects With Cervical Dystonia Completed NCT01588574 Phase 2
41 Amlodipine Plus Botulinum Toxin for Focal Dystonia Completed NCT00015457 Phase 2 Amlodipine plus Botulinum toxin
42 Deep Brain Stimulation for Cervical Dystonia Completed NCT00105430 Phase 2
43 An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects Completed NCT00280384 Phase 2 E2014 (Botulinum toxin type B);E2014 (Botulinum toxin type B) Placebo
44 Deep Brain Stimulation in Patients With Dystonia Completed NCT00773604 Phase 1, Phase 2
45 Clinical and Kinematic Assessment for Determination of Botox® Injection Parameters in Cervical Dystonia Recruiting NCT02662530 Phase 2 Botulinum Toxin Type A
46 Safety and Tolerability of Perampanel in Cervical Dystonia Recruiting NCT02131467 Phase 1, Phase 2 Perampanel
47 Keppra for Cervical Dystonia Terminated NCT00760318 Phase 2 Keppra
48 Botulinum Toxin Injection Efficiency Unknown status NCT01041157 Phase 1
49 PurTox (Botulinum Toxin Type A) for the Treatment of Adult Onset Spasmodic Torticollis/Cervical Dystonia Completed NCT00549341 Phase 1 Mentor Purified Toxin, Botulinum Toxn Type A, Purified Neurotoxin
50 Deep Brain Stimulation to Treat Cervical Dystonia Completed NCT00132340 Phase 1

Search NIH Clinical Center for Cervical Dystonia

Genetic Tests for Cervical Dystonia

Anatomical Context for Cervical Dystonia

MalaCards organs/tissues related to Cervical Dystonia:

41
Brain, Globus Pallidus, Subthalamic Nucleus, Testes, Cortex, Spinal Cord, Heart

Publications for Cervical Dystonia

Articles related to Cervical Dystonia:

(show top 50) (show all 1050)
# Title Authors Year
1
INTEREST IN CD2, a global patient-centred study of long-term cervical dystonia treatment with botulinum toxin. ( 29270685 )
2018
2
Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography. ( 29565281 )
2018
3
Pedunculopontine Nucleus Cholinergic Deficiency in Cervical Dystonia. ( 29508906 )
2018
4
Speech induced cervical dystonia: An unusual task specific dystonia. ( 29174183 )
2018
5
The effects of a relaxation program featuring aquatic therapy and autogenic training among people with cervical dystonia (a pilot study). ( 29939827 )
2018
6
A 500A U/2A mL dilution of abobotulinumtoxinA vs. placebo: randomized study in cervical dystonia. ( 29343142 )
2018
7
Abnormal cerebellar processing of the neck proprioceptive information drives dysfunctions in cervical dystonia. ( 29396401 )
2018
8
Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia. ( 29443021 )
2018
9
GABA<sub>A</sub> Receptor Availability Changes Underlie Symptoms in Isolated Cervical Dystonia. ( 29670567 )
2018
10
The premotor syndrome of cervical dystonia: Disordered processing of salient environmental stimuli. ( 29205495 )
2018
11
Personalized botulinum toxin type A therapy for cervical dystonia based on kinematic guidance. ( 29557988 )
2018
12
Long-term quality of life in cervical dystonia after treatment with abobotulinum toxin A: a 2-year prospective study. ( 29731634 )
2018
13
Physiological effects of subthalamic nucleus deep brain stimulation surgery in cervical dystonia. ( 29326293 )
2018
14
High prevalence of olfactory dysfunction in cervical dystonia. ( 29724603 )
2018
15
Postural control and the relation with cervical sensorimotor control in patients with idiopathic adult-onset cervical dystonia. ( 29340715 )
2018
16
The effects of a laser-guided postural reeducation program on pain, neck active range of motion, and functional improvement in a 75-year-old patient with cervical dystonia. ( 29939800 )
2018
17
Sonographic Guide for Botulinum Toxin Injections of the Neck Muscles in Cervical Dystonia. ( 29173657 )
2018
18
Changes in sensorimotor network activation after botulinum toxin type A injections in patients with cervical dystonia: a functional MRI study. ( 29971454 )
2018
19
Is perception of visual verticality intact in patients with idiopathic cervical dystonia? ( 29101737 )
2018
20
Cervical dystonia and substance abuse. ( 29569175 )
2018
21
Botulinum Toxin Type A Injection for Cervical Dystonia in Adults with Dyskinetic Cerebral Palsy. ( 29772695 )
2018
22
Cortical modulation of brainstem circuits is abnormal in cervical dystonia. ( 29704573 )
2018
23
Adverse events with botulinum toxin treatment in cervical dystonia: How much should we blame placebo? ( 29910156 )
2018
24
Randomised controlled trial of escitalopram for cervical dystonia with dystonic jerks/tremor. ( 29326295 )
2018
25
Pilot Study of a Device to Induce the Hanger Reflex in Patients with Cervical Dystonia. ( 29607887 )
2018
26
Relationships between Serotonin Transporter Binding in the Raphe Nuclei, Basal Ganglia, and Hippocampus with Clinical Symptoms in Cervical Dystonia: A [<sup>11</sup>C]DASB Positron Emission Tomography Study. ( 29541052 )
2018
27
Sexual dysfunction in cervical dystonia and blepharospasm. ( 30464469 )
2018
28
Oropharyngeal Dysphagia in Adults With Dyskinetic Cerebral Palsy and Cervical Dystonia: A Preliminary Study. ( 29958905 )
2018
29
Quality of life improvements in patients with cervical dystonia following treatment with a liquid formulation of abobotulinumtoxinA (Dysport® ). ( 30168896 )
2018
30
The effect of a single botulinum toxin treatment on somatosensory processing in idiopathic isolated cervical dystonia: an observational study. ( 30196326 )
2018
31
Ultrasound-Guided Botulinum Toxin Injections in Cervical Dystonia Needs Prompt Muscle Selection, Appropriate Dosage and Precise Guidance. ( 30198913 )
2018
32
Cervical Dystonia in Modigliani's Paintings: The Clue Was the Sensory Trick. ( 30363431 )
2018
33
Deep Brain Stimulation Versus Peripheral Denervation for Cervical Dystonia: A Systematic Review and Meta-Analysis. ( 30419402 )
2018
34
Reduced Frequency of Ipsilateral Express Saccades in Cervical Dystonia: Probing the Nigro-Tectal Pathway. ( 30510845 )
2018
35
Sensory trick efficacy in cervical dystonia is linked to processing of neck proprioception. ( 30553617 )
2018
36
Quetiapine-induced cervical dystonia. ( 26635371 )
2018
37
Selective Cervical Denervation for Cervical Dystonia: Modification of the Bertrand Procedure. ( 29106650 )
2018
38
Sertraline induced cervical dystonia in a patient of Obsessive Compulsive Disorder. ( 29447992 )
2018
39
Spectrum of practice in the routine management of cervical dystonia with abobotulinumtoxinA: findings from three prospective open-label observational studies. ( 30002865 )
2018
40
Injectable DaxibotulinumtoxinA in Cervical Dystonia: A Phase 2 Dose-Escalation Multicenter Study. ( 30009213 )
2018
41
Cervical dystonia: Normal auditory mismatch negativity and abnormal somatosensory mismatch negativity. ( 30015084 )
2018
42
'Author's Response to Letter to the Editor On 'Ultrasound-Guided Botulinum Toxin Injections in Cervical Dystonia Needs Prompt Muscle Selection, Appropriate Dosage and Precise Guidance'. ( 30096053 )
2018
43
Cervical Dystonia and Executive Function: A Pilot Magnetoencephalography Study. ( 30135369 )
2018
44
Acupuncture as Adjuvant Therapy for the Management of Cervical Dystonia. ( 30147821 )
2018
45
Quality of life in long-term botulinum toxin treatment of cervical dystonia: Results of a cross sectional study. ( 30150129 )
2018
46
Parkinsonian signs in patients with cervical dystonia treated with pallidal deep brain stimulation. ( 30165511 )
2018
47
Erratum to: "Spasmodic torticollis after orthognathic surgery" [J. Stomatol. Oral Maxillofac. Surg. 118 (2017) 393-6]. ( 29339087 )
2018
48
Treatment satisfaction with botulinum toxin: a comparison between blepharospasm and cervical dystonia. ( 29066869 )
2017
49
Endophenotyping in idiopathic adult onset cervical dystonia. ( 28511126 )
2017
50
Alterations of resting-state fMRI measurements in individuals with cervical dystonia. ( 28504361 )
2017

Variations for Cervical Dystonia

Expression for Cervical Dystonia

Search GEO for disease gene expression data for Cervical Dystonia.

Pathways for Cervical Dystonia

Pathways related to Cervical Dystonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.81 GNAL HLA-DQA1 HLA-DQB1
2 11.38 CAMP HLA-DQA1 HLA-DQB1
3 10.93 GNAL HLA-DQA1 HLA-DQB1
4 10.65 GNAL HLA-DQA1 HLA-DQB1

GO Terms for Cervical Dystonia

Cellular components related to Cervical Dystonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transport vesicle membrane GO:0030658 9.26 HLA-DQA1 HLA-DQB1
2 clathrin-coated endocytic vesicle membrane GO:0030669 9.16 HLA-DQA1 HLA-DQB1
3 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 8.96 HLA-DQA1 HLA-DQB1
4 MHC class II protein complex GO:0042613 8.62 HLA-DQA1 HLA-DQB1

Biological processes related to Cervical Dystonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 antigen processing and presentation GO:0019882 9.26 HLA-DQA1 HLA-DQB1
2 negative regulation of blood pressure GO:0045776 9.16 DRD5 GCH1
3 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 8.96 HLA-DQA1 HLA-DQB1
4 regulation of protein localization to cell surface GO:2000008 8.62 BDNF TOR1A

Molecular functions related to Cervical Dystonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 8.96 HLA-DQA1 HLA-DQB1
2 MHC class II receptor activity GO:0032395 8.62 HLA-DQA1 HLA-DQB1

Sources for Cervical Dystonia

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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44 MeSH
45 MESH via Orphanet
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49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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