MCID: CRV045
MIFTS: 43

Cervical Intraepithelial Neoplasia

Categories: Rare diseases

Aliases & Classifications for Cervical Intraepithelial Neoplasia

MalaCards integrated aliases for Cervical Intraepithelial Neoplasia:

Name: Cervical Intraepithelial Neoplasia 53 55 73

Classifications:



External Ids:

UMLS 73 C0206708

Summaries for Cervical Intraepithelial Neoplasia

MalaCards based summary : Cervical Intraepithelial Neoplasia is related to cervix uteri carcinoma in situ and suppressor of tumorigenicity 3. An important gene associated with Cervical Intraepithelial Neoplasia is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways/superpathways are Pathways in cancer and Validated targets of C-MYC transcriptional activation. The drugs Bupivacaine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include testes, cervix and t cells, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and mortality/aging

Wikipedia : 76 Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of... more...

Related Diseases for Cervical Intraepithelial Neoplasia

Diseases related to Cervical Intraepithelial Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 cervix uteri carcinoma in situ 33.1 CDKN2A FHIT KRT17
2 suppressor of tumorigenicity 3 31.1 CDKN2A FHIT
3 cervical squamous cell carcinoma 31.0 CDKN2A KRT8 MKI67
4 bowenoid papulosis 30.9 CDKN2A TERT
5 papilloma 30.6 CDKN2A KRT8 ODC1
6 cervical cancer 29.5 BIRC5 CDKN2A FHIT TERC TERT VEGFC
7 cervicitis 11.3
8 spitz nevus 10.8 CDKN2A MKI67
9 ameloblastic carcinoma 10.8 CDKN2A MKI67
10 endometrial mucinous adenocarcinoma 10.8 CDKN2A MKI67
11 dyskeratosis congenita, autosomal dominant 1 10.7 TERC TERT
12 oral leukoplakia 10.7 CDKN2A MKI67
13 inherited bone marrow failure syndromes 10.7 TERC TERT
14 acral lentiginous melanoma 10.7 CDKN2A TERT
15 bowen's disease 10.7 KRT17 MKI67
16 infiltrating angiolipoma 10.6 CDKN2A VEGFC
17 pleomorphic liposarcoma 10.6 CDKN2A KRT8
18 anal canal carcinoma 10.6 CDKN2A NME1
19 squamous cell carcinoma 10.6
20 soft tissue sarcoma 10.6 MKI67 TERT
21 necrotizing sialometaplasia 10.5 CDKN2A MKI67
22 cervical clear cell adenocarcinoma 10.5 CDKN2A KRT8
23 cryptogenic cirrhosis 10.5 KRT8 MTHFR
24 nasal cavity squamous cell carcinoma 10.5 CDKN2A KRT8
25 mesenteric vascular occlusion 10.5 MTHFR ODC1
26 aging 10.4
27 gastrointestinal stromal tumor 10.4 CDKN2A MKI67 MTHFR
28 benign meningioma 10.4 BIRC5 MKI67 TERT
29 dyskeratosis congenita autosomal dominant 10.4 TERC TERT
30 vaginitis 10.4
31 inverted papilloma 10.4 CDKN2A MKI67
32 basaloid squamous cell carcinoma 10.3 CDKN2A KRT17 KRT8
33 adenocarcinoma 10.3
34 endocervicitis 10.3
35 tongue cancer 10.3 CDKN2A TERT VEGFC
36 megaesophagus 10.3 CDKN2A FHIT
37 adenocarcinoma in situ 10.2
38 chlamydia 10.2
39 bacterial vaginosis 10.2
40 breast fibroadenoma 10.1 KRT8 MKI67 NME1
41 retinoblastoma 10.1
42 mucositis 10.1
43 leukoplakia 10.1 KRT8 MKI67
44 differentiated thyroid carcinoma 10.1 CDKN2A FHIT MTHFR
45 vaginal cancer 10.0
46 conjunctivitis 10.0
47 vulvar intraepithelial neoplasia 10.0
48 endotheliitis 10.0
49 keratocystic odontogenic tumor 10.0 BIRC5 FHIT MKI67
50 skin melanoma 10.0 CDKN2A MKI67 NME1 TERT

Graphical network of the top 20 diseases related to Cervical Intraepithelial Neoplasia:



Diseases related to Cervical Intraepithelial Neoplasia

Symptoms & Phenotypes for Cervical Intraepithelial Neoplasia

GenomeRNAi Phenotypes related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 CDC6 MKI67 RBL1

MGI Mouse Phenotypes related to Cervical Intraepithelial Neoplasia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.7 BIRC5 CDKN2A FHIT KRT17 KRT8 MTHFR
2 digestive/alimentary MP:0005381 9.63 CDKN2A FHIT KRT17 KRT8 RBL1 TERT
3 neoplasm MP:0002006 9.02 FHIT NME1 RBL1 TERT CDKN2A

Drugs & Therapeutics for Cervical Intraepithelial Neoplasia

Drugs for Cervical Intraepithelial Neoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 197)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
2
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
3
Aluminum hydroxide Approved, Investigational Phase 4,Phase 3 21645-51-2
4
Racepinephrine Approved Phase 4,Phase 3,Phase 2 329-65-7 838
5
alemtuzumab Approved, Investigational Phase 4 216503-57-0
6 Anesthetics Phase 4,Phase 3,Phase 2,Not Applicable
7 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable
9 Respiratory System Agents Phase 4,Phase 2
10 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
11 Adrenergic Agents Phase 4,Phase 2
12 Adrenergic Agonists Phase 4,Phase 2
13 Adrenergic alpha-Agonists Phase 4,Phase 2
14 Adrenergic beta-Agonists Phase 4,Phase 2
15 Mydriatics Phase 4,Phase 2
16 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
17 Hormone Antagonists Phase 4,Phase 2
18 Anesthetics, Local Phase 4,Phase 3,Phase 2
19 Hormones Phase 4,Phase 2
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
21 Vasoconstrictor Agents Phase 4,Phase 2
22 Anti-Asthmatic Agents Phase 4,Phase 2
23 Epinephryl borate Phase 4,Phase 3,Phase 2
24 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
25 Estrogens Phase 4
26 Estrogens, Conjugated (USP) Phase 4
27 Autonomic Agents Phase 4,Phase 2,Not Applicable
28 Bronchodilator Agents Phase 4,Phase 2
29 Monophosphoryl lipid A Phase 4
30
Menthol Approved Phase 2, Phase 3,Phase 3,Not Applicable 2216-51-5 16666
31
Lidocaine Approved, Vet_approved Phase 3,Phase 2,Not Applicable 137-58-6 3676
32
Isotretinoin Approved Phase 3 4759-48-2 5538 5282379
33
Imiquimod Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 99011-02-6 57469
34
Fluorouracil Approved Phase 3,Phase 1 51-21-8 3385
35
Aluminum sulfate Approved Phase 3 10043-01-3
36
acetic acid Approved, Nutraceutical Phase 3,Phase 1,Not Applicable 64-19-7 176
37
leucovorin Approved, Nutraceutical Phase 3,Phase 2 58-05-9 143 6006
38
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-30-3 6037
39
Fenretinide Investigational Phase 3 65646-68-6
40
3,3'-diindolylmethane Investigational Phase 3 1968-05-4
41
Retinol acetate Phase 3,Phase 1,Not Applicable 127-47-9 10245972
42 interferons Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
43 Adjuvants, Immunologic Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
44 Gastrointestinal Agents Phase 3,Phase 2,Phase 1
45 Antibodies Phase 3,Phase 1,Phase 2
46 Immunoglobulins Phase 3,Phase 1,Phase 2
47 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Interferon Inducers Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
49 Protective Agents Phase 3,Phase 1,Phase 2,Not Applicable
50 Antiviral Agents Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 349)
# Name Status NCT ID Phase Drugs
1 Can Alternative Treatment Have an Impact on Cervical Dysplasia? Unknown status NCT00842738 Phase 4
2 Management of Cervical Intraepithelial Neoplasia Grade 2 Completed NCT00733109 Phase 4
3 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed NCT01544478 Phase 4
4 Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization Completed NCT02368054 Phase 4 Bupivacaine;Adrenaline
5 Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease Completed NCT01034358 Phase 4
6 Effect of Hormone Replacement Therapy on Lupus Activity Completed NCT00392093 Phase 4 Conjugated equine estrogens 0.625 mg/d + MPA 5 mg/d/10d
7 HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions Recruiting NCT03051516 Phase 4
8 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Active, not recruiting NCT02629510 Phase 4 Tachosil
9 FASTER-Tlalpan Study Active, not recruiting NCT03105856 Phase 4
10 CervIcal Cancer Screening Trial by Randomization of HPV Testing Intervention for Upcoming Screening (CITRUS Study) Active, not recruiting NCT01895517 Phase 4
11 Phase IIIB-IV Long-Term Follow-up Study for Patients Who Participated in CAMMS03409 Active, not recruiting NCT02255656 Phase 4 alemtuzumab GZ402673
12 Effectiveness of Cervical Screening in HPV Vaccinated Women Enrolling by invitation NCT02149030 Phase 4
13 Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) Unknown status NCT01095198 Phase 2, Phase 3
14 ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial Completed NCT00941252 Phase 2, Phase 3 Topical imiquimod therapy
15 Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants Completed NCT00128661 Phase 3
16 Oral Diindolylmethane (DIM) for the Treatment of Cervical Dysplasia Completed NCT00212381 Phase 3 di indolylmethane (DIM)
17 Forced Versus Spray Coagulation in Women Undergoing LLETZ-conization for Cervical Dysplasia: a Randomized Trial Completed NCT02330471 Phase 3
18 Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix Completed NCT02130323 Phase 2, Phase 3 Imiquimod
19 Extension Study of the Efficacy of the GSK 580299 Vaccine in Japanese Women Vaccinated in the Primary NCT00316693 Study Completed NCT00929526 Phase 3
20 Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit Completed NCT00237562 Phase 3
21 A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women Completed NCT00000758 Phase 3 Fluorouracil
22 Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED) Completed NCT00092521 Phase 3
23 A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine Cervix Completed NCT00264732 Phase 2, Phase 3 Amolimogene;Amolimogene
24 Lidocaine Spray Compared With Submucosal Injection During LEEP: a Randomized Controlled Trial Completed NCT01505920 Phase 3
25 Fenretinide in Treating Patients With Cervical Neoplasia Completed NCT00003075 Phase 3 Fenretinide
26 A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins Completed NCT01929993 Phase 3
27 Diindolylmethane in Treating Patients With Abnormal Cervical Cells Completed NCT00462813 Phase 3 oral microencapsulated diindolylmethane
28 Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1 Completed NCT00156026 Phase 3
29 Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) Completed NCT01131312 Phase 3
30 Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion Completed NCT00995020 Phase 3
31 Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women Completed NCT00337818 Phase 3
32 Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine Completed NCT00316706 Phase 3
33 Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil)(V501-015) Completed NCT00092534 Phase 3
34 Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18 Completed NCT00122681 Phase 3
35 Self-sampling and Human Papillomavirus (HPV)-Testing for Unscreened Women in Cervical Cancer Prevention Completed NCT01014026 Phase 3
36 Efficacy, Immunogenicity and Safety of GSK Biologicals' HPV GSK 580299 Vaccine in Healthy Chinese Female Subjects Completed NCT00779766 Phase 3
37 Study to Evaluate the Efficacy of the Human Papillomavirus Vaccine in Healthy Adult Women of 26 Years of Age and Older Completed NCT00294047 Phase 3
38 A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls Completed NCT02562508 Phase 3
39 A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019) Completed NCT00090220 Phase 3
40 Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors Completed NCT00001073 Phase 3 Isotretinoin
41 Prevention of Human Papillomavirus (HPV) in 20 to 45 Year Old Chinese Women (V501-041) Completed NCT00834106 Phase 3
42 Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System Completed NCT00973362 Phase 3
43 Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001) Completed NCT00543543 Phase 3
44 A Study of Gardasil (V501) in Preadolescents and Adolescents (V501-018) Completed NCT00092547 Phase 3
45 Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol Recruiting NCT02669459 Phase 3 Imiquimod
46 REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) Recruiting NCT03185013 Phase 3
47 A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study Recruiting NCT03355820 Phase 3
48 The Study of Folate Receptor-Mediated Staining Solution (FRD™) In Cervical Lesion Detection Recruiting NCT03366493 Phase 3
49 Impact of AV2 Antiviral Drug on the Treatment of HPV-associated Lesions of the Uterine Cervix Recruiting NCT02346227 Phase 3 AV2;Placebo
50 Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial Neoplasia Recruiting NCT01861535 Phase 3 Imiquimod

Search NIH Clinical Center for Cervical Intraepithelial Neoplasia

Genetic Tests for Cervical Intraepithelial Neoplasia

Anatomical Context for Cervical Intraepithelial Neoplasia

MalaCards organs/tissues related to Cervical Intraepithelial Neoplasia:

41
Testes, Cervix, T Cells, Skin, Bone, Kidney, Bone Marrow

Publications for Cervical Intraepithelial Neoplasia

Articles related to Cervical Intraepithelial Neoplasia:

(show top 50) (show all 845)
# Title Authors Year
1
Non-steroidal anti-inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia. ( 29431861 )
2018
2
Risks of cervical intraepithelial neoplasia grade 3 or invasive cancers in ASCUS women with different management: a population-based cohort study. ( 29770625 )
2018
3
A prospective study on the predictive value of DNA methylation in cervical intraepithelial neoplasia prognosis. ( 29971561 )
2018
4
Hormonal contraceptive use and smoking as risk factors for high-grade cervical intraepithelial neoplasia in unvaccinated women aged 30-44 years: A case-control study in New South Wales, Australia. ( 29980028 )
2018
5
New biomarkers of human papillomavirus infection in acute cervical intraepithelial neoplasia. ( 29966832 )
2018
6
Distribution and role of high-risk human papillomavirus genotypes in women with cervical intraepithelial neoplasia: A retrospective analysis from Wenzhou, southeast China. ( 29851256 )
2018
7
Presence of koilocytosis in low-grade smears of high-risk HPV-positive women is a negative predictor for cervical intraepithelial neoplasia grade 3 or more. ( 29575519 )
2018
8
Clinical outcomes after conservative management of cervical intraepithelial neoplasia grade 2 (CIN2) in women ages 21-39 years. ( 29437696 )
2018
9
TOPical Imiquimod treatment of residual or recurrent cervical intraepithelial neoplasia (TOPIC-2 trial): a study protocol for a randomized controlled trial. ( 29902979 )
2018
10
Diagnostic value of human papillomavirus (HPV) 16 and HPV18 viral loads for the detection of high-grade cervical intraepithelial neoplasia (CIN2+) in a cohort of African women living with HIV. ( 29353074 )
2018
11
Risk of preterm birth in women with cervical intraepithelial neoplasia grade one: a population-based cohort study. ( 29165793 )
2018
12
Medical Devices; Hematology and Pathology Devices; Classification of a Cervical Intraepithelial Neoplasia Test System. Final order. ( 29319946 )
2018
13
The direct and indirect association of cervical microbiota with the risk of cervical intraepithelial neoplasia. ( 29608253 )
2018
14
Programmed death-1 (PD-1) expression in cervical intraepithelial neoplasia and its relationship with recurrence after conization. ( 29400020 )
2018
15
Clinical and Economic Value of p16INK4a for the Differential Diagnosis of Morphologic Cervical Intraepithelial Neoplasia 2. ( 29734247 )
2018
16
Factors affecting residual/recurrent cervical intraepithelial neoplasia after cervical conization with negative margins. ( 29704442 )
2018
17
Low recurrence rate of high-grade cervical intraepithelial neoplasia after successful excision and routine colposcopy during follow-up. ( 29369205 )
2018
18
Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation. ( 29319498 )
2018
19
Depth of Cervical Intraepithelial Neoplasia Grade 3 in Peruvian Women: Implications for Therapeutic Depth of Necrosis. ( 29271853 )
2018
20
Risk for Cervical Intraepithelial Neoplasia Grade 3 or Higher in Follow-Up of Women With a Negative Cervical Biopsy. ( 29543686 )
2018
21
Effect of Screening With Primary Cervical HPV Testing vs Cytology Testing on High-grade Cervical Intraepithelial Neoplasia at 48 Months: The HPV FOCAL Randomized Clinical Trial. ( 29971397 )
2018
22
Cervical microbiome is altered in cervical intraepithelial neoplasia after loop electrosurgical excision procedure in china. ( 29563617 )
2018
23
Characteristic findings of high-grade cervical intraepithelial neoplasia or more on magnifying endoscopy with narrow band imaging. ( 29446041 )
2018
24
Influence of age on histologic outcome of cervical intraepithelial neoplasia during observational management: results from large cohort, systematic review, meta-analysis. ( 29686397 )
2018
25
Prevalence of high-grade cervical intraepithelial neoplasia in women with persistent high-risk HPV genotypes and negative cytology. ( 29350424 )
2018
26
Differentiated cervical intraepithelial neoplasia-associated invasive cervical squamous cell carcinoma as a source of major cytopathological and surgical pathological discrepancy in Papanicolaou smear screening tests. ( 29575422 )
2018
27
Is self-sampling to test for high-risk papillomavirus an acceptable option among women who have been treated for high-grade cervical intraepithelial neoplasia? ( 29912903 )
2018
28
Analysis of differential gene expression caused by cervical intraepithelial neoplasia based on GEO database. ( 29805564 )
2018
29
Mass spectrometry and multivariate analysis to classify cervical intraepithelial neoplasia from blood plasma: an untargeted lipidomic study. ( 29500376 )
2018
30
Efficacy and safety of photodynamic therapy for cervical intraepithelial neoplasia and human papilloma virus infection: A systematic review and meta-analysis of randomized clinical trials. ( 29794788 )
2018
31
Suppressive antiretroviral therapy associates with effective treatment of high-grade cervical intraepithelial neoplasia. ( 29746299 )
2018
32
Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study. ( 29404740 )
2018
33
Using p16 immunohistochemistry to classify morphologic cervical intraepithelial neoplasia 2: correlation of ambiguous staining patterns with HPV subtypes and clinical outcome. ( 28705710 )
2017
34
Loop Electrosurgical Excision Procedure<i>vs</i>. Cold Knife Cone in Treatment of Cervical Intraepithelial Neoplasia: Review of 447 Cases. ( 29263039 )
2017
35
The impact of bivalent HPV vaccine on cervical intraepithelial neoplasia by deprivation in Scotland: reducing the gap. ( 28756395 )
2017
36
A prediction model for spontaneous regression of cervical intraepithelial neoplasia grade 2, based on simple clinical parameters. ( 27697590 )
2017
37
Authors' reply re: Assessing cervical intraepithelial neoplasia as an indicator disease for HIV in a low endemic setting: a population-based register study. ( 28921796 )
2017
38
A retrospective analysis on 1901 women with high grade cervical intraepithelial neoplasia by colposcopic biopsy. ( 28850822 )
2017
39
Bacterial Vaginosis and Cervical Intraepithelial Neoplasia: Is there an Association or is Co-Existence Incidental? ( 28610416 )
2017
40
Expressions of programmed death (PD)-1 and PD-1 ligand (PD-L1) in cervical intraepithelial neoplasia and cervical squamous cell carcinomas are of prognostic value and associated with human papillomavirus status. ( 28833798 )
2017
41
Inhibition of MMP-9 expression by ritonavir or saquinavir is associated with inactivation of the AKT/Fra-1 pathway in cervical intraepithelial neoplasia cells. ( 28521396 )
2017
42
Cryotherapy reduces progression of cervical intraepithelial neoplasia grade 1 in South African HIV-infected women: a randomized, controlled trial. ( 28902073 )
2017
43
LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia. ( 28854904 )
2017
44
Discrepant HPV/cytology cotesting results: Are there differences between cytology-negative versus HPV-negative cervical intraepithelial neoplasia? ( 28817235 )
2017
45
Diagnostic and Treatment Reproducibility of Cervical Intraepithelial Neoplasia / Squamous Intraepithelial Lesion and Factors Affecting the Diagnosis. ( 28832077 )
2017
46
Effects of Long-Term Vitamin D Supplementation on Regression and Metabolic Status of Cervical Intraepithelial Neoplasia: a Randomized, Double-Blind, Placebo-Controlled Trial. ( 28050798 )
2017
47
Expression of p63, p53 and Ki-67 in Patients with Cervical Intraepithelial Neoplasia. ( 28044307 )
2017
48
Type-Dependent Association between Risk of Cervical Intraepithelial Neoplasia and Viral Load of Oncogenic Human Papillomavirus Types Other than Types 16 and 18. ( 28052328 )
2017
49
Increased Cervical HIV RNA Shedding Among HIV-Infected Women Randomized to Loop Electrosurgical Excision Procedure (LEEP) compared to Cryotherapy for Cervical Intraepithelial Neoplasia 2/3. ( 29272368 )
2017
50
Translation and cultural adaptation of the Functional Assessment of Chronic Illness Therapy - Cervical Dysplasia (FACIT-CD) to evaluate quality of life in women with cervical intraepithelial neoplasia. ( 28767912 )
2017

Variations for Cervical Intraepithelial Neoplasia

Expression for Cervical Intraepithelial Neoplasia

Search GEO for disease gene expression data for Cervical Intraepithelial Neoplasia.

Pathways for Cervical Intraepithelial Neoplasia

Pathways related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.07 BIRC5 CDKN2A TERC TERT VEGFC
2 10.83 BIRC5 NME1 ODC1 TERT

GO Terms for Cervical Intraepithelial Neoplasia

Cellular components related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.65 BIRC5 CDC6 CDKN2A FHIT KRT17 KRT8
2 intermediate filament GO:0005882 9.43 KRT17 KRT8 NME1
3 telomerase holoenzyme complex GO:0005697 9.16 TERC TERT
4 telomerase catalytic core complex GO:0000333 8.62 TERC TERT

Biological processes related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.62 CDC6 CDKN2A NME1 VEGFC
2 DNA biosynthetic process GO:0071897 9.4 TERC TERT
3 nucleotide metabolic process GO:0009117 9.37 FHIT NME1
4 cell cycle GO:0007049 9.35 BIRC5 CDC6 CDKN2A MKI67 RBL1
5 telomere maintenance via telomerase GO:0007004 9.26 TERC TERT
6 replicative senescence GO:0090399 9.16 CDKN2A TERT
7 negative regulation of cellular senescence GO:2000773 8.8 RBL1 TERC TERT

Molecular functions related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 telomerase activity GO:0003720 9.16 TERC TERT
2 RNA-directed DNA polymerase activity GO:0003964 8.96 TERC TERT
3 telomerase RNA reverse transcriptase activity GO:0003721 8.62 TERC TERT
4 protein binding GO:0005515 10.07 BIRC5 CDC6 CDKN2A FHIT KRT17 KRT8

Sources for Cervical Intraepithelial Neoplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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