CIN
MCID: CRV045
MIFTS: 45

Cervical Intraepithelial Neoplasia (CIN)

Categories: Rare diseases

Aliases & Classifications for Cervical Intraepithelial Neoplasia

MalaCards integrated aliases for Cervical Intraepithelial Neoplasia:

Name: Cervical Intraepithelial Neoplasia 53 55 73
Cin 48

Classifications:



External Ids:

UMLS 73 C0206708

Summaries for Cervical Intraepithelial Neoplasia

MalaCards based summary : Cervical Intraepithelial Neoplasia, also known as cin, is related to cervix uteri carcinoma in situ and suppressor of tumorigenicity 3. An important gene associated with Cervical Intraepithelial Neoplasia is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways/superpathways are Pathways in cancer and Validated targets of C-MYC transcriptional activation. The drugs Epinephrine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include testes, cervix and t cells, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and mortality/aging

Wikipedia : 76 Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of... more...

Related Diseases for Cervical Intraepithelial Neoplasia

Diseases related to Cervical Intraepithelial Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 cervix uteri carcinoma in situ 32.8 CDKN2A KRT17
2 suppressor of tumorigenicity 3 31.0 CDKN2A FHIT
3 papilloma 30.9 CDKN2A KRT8 ODC1
4 cervical squamous cell carcinoma 30.8 CDKN2A KRT8 MKI67
5 bowenoid papulosis 30.3 CDKN2A TERT
6 cervical cancer 30.2 BIRC5 CDC6 CDKN2A FHIT NME1 TERC
7 colorectal cancer 29.3 BIRC5 CDKN2A FHIT MTHFR NME1 ODC1
8 breast cancer 28.8 BIRC5 FHIT KRT8 MKI67 NME1 ODC1
9 squamous cell carcinoma 10.7
10 adenocarcinoma 10.4
11 adenocarcinoma in situ 10.4
12 immunodeficiency-centromeric instability-facial anomalies syndrome 1 10.4
13 anogenital venereal wart 10.4
14 viral infectious disease 10.4
15 chlamydia 10.3
16 bacterial vaginosis 10.3
17 human immunodeficiency virus infectious disease 10.3
18 cervicitis 10.3
19 spitz nevus 10.3 CDKN2A MKI67
20 ameloblastic carcinoma 10.3 CDKN2A MKI67
21 endometrial mucinous adenocarcinoma 10.3 CDKN2A MKI67
22 malignant peritoneal mesothelioma 10.2 BIRC5 CDKN2A
23 acral lentiginous melanoma 10.2 CDKN2A TERT
24 inherited bone marrow failure syndromes 10.2 TERC TERT
25 vulva squamous cell carcinoma 10.2 CDKN2A KRT17
26 oral leukoplakia 10.2 CDKN2A MKI67
27 bowen's disease 10.2 KRT17 MKI67
28 retinoblastoma 10.2
29 squamous cell papilloma 10.2
30 nasal cavity cancer 10.2 CDKN2A KRT8
31 infiltrating angiolipoma 10.2 CDKN2A VEGFC
32 dyskeratosis congenita, autosomal dominant 1 10.2 TERC TERT
33 uterus carcinoma in situ 10.2 CDKN2A KRT17
34 cryptogenic cirrhosis 10.2 KRT8 MTHFR
35 pleomorphic liposarcoma 10.2 CDKN2A KRT8
36 revesz syndrome 10.2 TERC TERT
37 soft tissue sarcoma 10.2 MKI67 TERT
38 dyskeratosis congenita autosomal dominant 10.2 TERC TERT
39 necrotizing sialometaplasia 10.2 CDKN2A MKI67
40 leukoplakia 10.2 KRT8 MKI67
41 anal canal carcinoma 10.2 CDKN2A NME1
42 mesenteric vascular occlusion 10.2 MTHFR ODC1
43 gastrointestinal stromal tumor 10.1 CDKN2A MKI67 MTHFR
44 nasal cavity squamous cell carcinoma 10.1 CDKN2A KRT8
45 breast adenoma 10.1 KRT17 ODC1
46 benign meningioma 10.1 BIRC5 MKI67 TERT
47 vaginal cancer 10.1
48 cervix carcinoma 10.1
49 in situ carcinoma 10.1
50 vulvar intraepithelial neoplasia 10.1

Graphical network of the top 20 diseases related to Cervical Intraepithelial Neoplasia:



Diseases related to Cervical Intraepithelial Neoplasia

Symptoms & Phenotypes for Cervical Intraepithelial Neoplasia

GenomeRNAi Phenotypes related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 CDC6 MKI67 RBL1

MGI Mouse Phenotypes related to Cervical Intraepithelial Neoplasia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.7 BIRC5 CDKN2A FHIT KRT17 KRT8 MTHFR
2 digestive/alimentary MP:0005381 9.63 CDKN2A FHIT KRT17 KRT8 RBL1 TERT
3 neoplasm MP:0002006 9.02 CDKN2A FHIT NME1 RBL1 TERT

Drugs & Therapeutics for Cervical Intraepithelial Neoplasia

Drugs for Cervical Intraepithelial Neoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 197)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
2
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
3
Racepinephrine Approved Phase 4,Phase 3,Phase 2 329-65-7 838
4
Aluminum hydroxide Approved, Investigational Phase 4,Phase 3 21645-51-2
5
alemtuzumab Approved, Investigational Phase 4 216503-57-0
6 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
7 Anesthetics Phase 4,Phase 3,Phase 2,Not Applicable
8 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable
9 Immunologic Factors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
10 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Not Applicable
11 Vasoconstrictor Agents Phase 4,Phase 2
12 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
13 Adrenergic alpha-Agonists Phase 4,Phase 2
14 Adrenergic beta-Agonists Phase 4,Phase 2
15 Anti-Asthmatic Agents Phase 4,Phase 2
16 Adrenergic Agents Phase 4,Phase 2
17 Mydriatics Phase 4,Phase 2
18 Anesthetics, Local Phase 4,Phase 3,Phase 2
19 Epinephryl borate Phase 4,Phase 3,Phase 2
20 Adrenergic Agonists Phase 4,Phase 2
21 Respiratory System Agents Phase 4,Phase 2
22 Autonomic Agents Phase 4,Phase 2,Not Applicable
23 Bronchodilator Agents Phase 4,Phase 2
24 Sympathomimetics Phase 4,Phase 2
25 Hormones Phase 4,Phase 2
26 Hormone Antagonists Phase 4,Phase 2
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
28 Estrogens, Conjugated (USP) Phase 4
29 Estrogens Phase 4
30 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
31 Monophosphoryl lipid A Phase 4
32
acetic acid Approved Phase 3,Phase 1,Not Applicable,Early Phase 1 64-19-7 176
33
Imiquimod Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 99011-02-6 57469
34
Fluorouracil Approved Phase 3,Phase 1 51-21-8 3385
35
Lidocaine Approved, Vet_approved Phase 3,Phase 2,Not Applicable 137-58-6 3676
36
Eugenol Approved Phase 3 97-53-0 3314
37
Isotretinoin Approved Phase 3 4759-48-2 5538 5282379
38
leucovorin Approved Phase 3,Phase 2 58-05-9 6006 143
39
Aluminum sulfate Approved Phase 3 10043-01-3
40
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-30-3 6037
41
3,3'-diindolylmethane Investigational Phase 3 1968-05-4
42
Fenretinide Investigational Phase 3 65646-68-6
43 Adjuvants, Immunologic Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable,Early Phase 1
44 Interferon Inducers Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
45 interferons Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
46 Protective Agents Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1
47 Immunoglobulins Phase 3
48 Antibodies Phase 3
49 Antiviral Agents Phase 3,Phase 2,Phase 1
50 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 364)
# Name Status NCT ID Phase Drugs
1 Can Alternative Treatment Have an Impact on Cervical Dysplasia? Unknown status NCT00842738 Phase 4
2 Management of Cervical Intraepithelial Neoplasia Grade 2 Completed NCT00733109 Phase 4
3 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed NCT01544478 Phase 4
4 Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization Completed NCT02368054 Phase 4 Bupivacaine;Adrenaline
5 Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease Completed NCT01034358 Phase 4
6 Effect of Hormone Replacement Therapy on Lupus Activity Completed NCT00392093 Phase 4 Conjugated equine estrogens 0.625 mg/d + MPA 5 mg/d/10d
7 Safety and Protective Effect Study of GSK Biologicals' Human Papillomavirus (Types 16, 18) Vaccine, Adsorbed (GSK580299) in Healthy Female Subjects From the HPV-039 Study Recruiting NCT03629886 Phase 4
8 HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions Recruiting NCT03051516 Phase 4
9 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Active, not recruiting NCT02629510 Phase 4 Tachosil
10 FASTER-Tlalpan Study Active, not recruiting NCT03105856 Phase 4
11 CervIcal Cancer Screening Trial by Randomization of HPV Testing Intervention for Upcoming Screening (CITRUS Study) Active, not recruiting NCT01895517 Phase 4
12 Phase IIIB-IV Long-Term Follow-up Study for Patients Who Participated in CAMMS03409 Active, not recruiting NCT02255656 Phase 4 alemtuzumab GZ402673
13 Effectiveness of Cervical Screening in HPV Vaccinated Women Enrolling by invitation NCT02149030 Phase 4
14 Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) Unknown status NCT01095198 Phase 2, Phase 3
15 ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial Completed NCT00941252 Phase 2, Phase 3 Topical imiquimod therapy
16 Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants Completed NCT00128661 Phase 3
17 Oral Diindolylmethane (DIM) for the Treatment of Cervical Dysplasia Completed NCT00212381 Phase 3 di indolylmethane (DIM)
18 Forced Versus Spray Coagulation in Women Undergoing LLETZ-conization for Cervical Dysplasia: a Randomized Trial Completed NCT02330471 Phase 3
19 Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) Completed NCT01131312 Phase 3
20 Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix Completed NCT02130323 Phase 2, Phase 3 Imiquimod
21 Extension Study of the Efficacy of the GSK 580299 Vaccine in Japanese Women Vaccinated in the Primary NCT00316693 Study Completed NCT00929526 Phase 3
22 Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit Completed NCT00237562 Phase 3
23 A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women Completed NCT00000758 Phase 3 Fluorouracil
24 Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED) Completed NCT00092521 Phase 3
25 A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine Cervix Completed NCT00264732 Phase 2, Phase 3 Amolimogene;Amolimogene
26 Lidocaine Spray Compared With Submucosal Injection During LEEP: a Randomized Controlled Trial Completed NCT01505920 Phase 3
27 Fenretinide in Treating Patients With Cervical Neoplasia Completed NCT00003075 Phase 3 Fenretinide
28 A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins Completed NCT01929993 Phase 3
29 Diindolylmethane in Treating Patients With Abnormal Cervical Cells Completed NCT00462813 Phase 3 oral microencapsulated diindolylmethane
30 A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study Completed NCT03355820 Phase 3
31 Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1 Completed NCT00156026 Phase 3
32 Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion Completed NCT00995020 Phase 3
33 Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women Completed NCT00337818 Phase 3
34 Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine Completed NCT00316706 Phase 3
35 Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil)(V501-015) Completed NCT00092534 Phase 3
36 Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18 Completed NCT00122681 Phase 3
37 Impact of AV2 Antiviral Drug on the Treatment of HPV-associated Lesions of the Uterine Cervix Completed NCT02346227 Phase 3 AV2;Placebo
38 Self-sampling and Human Papillomavirus (HPV)-Testing for Unscreened Women in Cervical Cancer Prevention Completed NCT01014026 Phase 3
39 Efficacy, Immunogenicity and Safety of GSK Biologicals' HPV GSK 580299 Vaccine in Healthy Chinese Female Subjects Completed NCT00779766 Phase 3
40 Study to Evaluate the Efficacy of the Human Papillomavirus Vaccine in Healthy Adult Women of 26 Years of Age and Older Completed NCT00294047 Phase 3
41 A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls Completed NCT02562508 Phase 3
42 A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019) Completed NCT00090220 Phase 3
43 Safety and Effectiveness of Giving Isotretinoin to HIV-Infected Women to Treat Cervical Tumors Completed NCT00001073 Phase 3 Isotretinoin
44 Prevention of Human Papillomavirus (HPV) in 20 to 45 Year Old Chinese Women (V501-041) Completed NCT00834106 Phase 3
45 Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System Completed NCT00973362 Phase 3
46 Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001) Completed NCT00543543 Phase 3
47 A Study of Gardasil (V501) in Preadolescents and Adolescents (V501-018) Completed NCT00092547 Phase 3
48 Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol Recruiting NCT02669459 Phase 3 Imiquimod
49 REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) Recruiting NCT03185013 Phase 3
50 The Study of Folate Receptor-Mediated Staining Solution (FRD™) In Cervical Lesion Detection Recruiting NCT03366493 Phase 3

Search NIH Clinical Center for Cervical Intraepithelial Neoplasia

Genetic Tests for Cervical Intraepithelial Neoplasia

Anatomical Context for Cervical Intraepithelial Neoplasia

MalaCards organs/tissues related to Cervical Intraepithelial Neoplasia:

41
Testes, Cervix, T Cells, Bone, Kidney, Breast, Liver

Publications for Cervical Intraepithelial Neoplasia

Articles related to Cervical Intraepithelial Neoplasia:

(show top 50) (show all 1608)
# Title Authors Year
1
Non-steroidal anti-inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia. ( 29431861 )
2018
2
Risks of cervical intraepithelial neoplasia grade 3 or invasive cancers in ASCUS women with different management: a population-based cohort study. ( 29770625 )
2018
3
A prospective study on the predictive value of DNA methylation in cervical intraepithelial neoplasia prognosis. ( 29971561 )
2018
4
Hormonal contraceptive use and smoking as risk factors for high-grade cervical intraepithelial neoplasia in unvaccinated women aged 30-44 years: A case-control study in New South Wales, Australia. ( 29980028 )
2018
5
New biomarkers of human papillomavirus infection in acute cervical intraepithelial neoplasia. ( 29966832 )
2018
6
Distribution and role of high-risk human papillomavirus genotypes in women with cervical intraepithelial neoplasia: A retrospective analysis from Wenzhou, southeast China. ( 29851256 )
2018
7
Presence of koilocytosis in low-grade smears of high-risk HPV-positive women is a negative predictor for cervical intraepithelial neoplasia grade 3 or more. ( 29575519 )
2018
8
Clinical outcomes after conservative management of cervical intraepithelial neoplasia grade 2 (CIN2) in women ages 21-39 years. ( 29437696 )
2018
9
TOPical Imiquimod treatment of residual or recurrent cervical intraepithelial neoplasia (TOPIC-2 trial): a study protocol for a randomized controlled trial. ( 29902979 )
2018
10
Diagnostic value of human papillomavirus (HPV) 16 and HPV18 viral loads for the detection of high-grade cervical intraepithelial neoplasia (CIN2+) in a cohort of African women living with HIV. ( 29353074 )
2018
11
Risk of preterm birth in women with cervical intraepithelial neoplasia grade one: a population-based cohort study. ( 29165793 )
2018
12
Medical Devices; Hematology and Pathology Devices; Classification of a Cervical Intraepithelial Neoplasia Test System. Final order. ( 29319946 )
2018
13
The direct and indirect association of cervical microbiota with the risk of cervical intraepithelial neoplasia. ( 29608253 )
2018
14
Programmed death-1 (PD-1) expression in cervical intraepithelial neoplasia and its relationship with recurrence after conization. ( 29400020 )
2018
15
Clinical and Economic Value of p16INK4a for the Differential Diagnosis of Morphologic Cervical Intraepithelial Neoplasia 2. ( 29734247 )
2018
16
Factors affecting residual/recurrent cervical intraepithelial neoplasia after cervical conization with negative margins. ( 29704442 )
2018
17
Low recurrence rate of high-grade cervical intraepithelial neoplasia after successful excision and routine colposcopy during follow-up. ( 29369205 )
2018
18
Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation. ( 29319498 )
2018
19
Depth of Cervical Intraepithelial Neoplasia Grade 3 in Peruvian Women: Implications for Therapeutic Depth of Necrosis. ( 29271853 )
2018
20
Risk for Cervical Intraepithelial Neoplasia Grade 3 or Higher in Follow-Up of Women With a Negative Cervical Biopsy. ( 29543686 )
2018
21
Effect of Screening With Primary Cervical HPV Testing vs Cytology Testing on High-grade Cervical Intraepithelial Neoplasia at 48 Months: The HPV FOCAL Randomized Clinical Trial. ( 29971397 )
2018
22
Cervical microbiome is altered in cervical intraepithelial neoplasia after loop electrosurgical excision procedure in china. ( 29563617 )
2018
23
Characteristic findings of high-grade cervical intraepithelial neoplasia or more on magnifying endoscopy with narrow band imaging. ( 29446041 )
2018
24
Influence of age on histologic outcome of cervical intraepithelial neoplasia during observational management: results from large cohort, systematic review, meta-analysis. ( 29686397 )
2018
25
Prevalence of high-grade cervical intraepithelial neoplasia in women with persistent high-risk HPV genotypes and negative cytology. ( 29350424 )
2018
26
Differentiated cervical intraepithelial neoplasia-associated invasive cervical squamous cell carcinoma as a source of major cytopathological and surgical pathological discrepancy in Papanicolaou smear screening tests. ( 29575422 )
2018
27
Is self-sampling to test for high-risk papillomavirus an acceptable option among women who have been treated for high-grade cervical intraepithelial neoplasia? ( 29912903 )
2018
28
Analysis of differential gene expression caused by cervical intraepithelial neoplasia based on GEO database. ( 29805564 )
2018
29
Mass spectrometry and multivariate analysis to classify cervical intraepithelial neoplasia from blood plasma: an untargeted lipidomic study. ( 29500376 )
2018
30
Efficacy and safety of photodynamic therapy for cervical intraepithelial neoplasia and human papilloma virus infection: A systematic review and meta-analysis of randomized clinical trials. ( 29794788 )
2018
31
Suppressive antiretroviral therapy associates with effective treatment of high-grade cervical intraepithelial neoplasia. ( 29746299 )
2018
32
Prevalence of human papillomavirus among Wenzhou women diagnosed with cervical intraepithelial neoplasia and cervical cancer. ( 30505342 )
2018
33
Evaluation of Anal Cytology in Women with History of Abnormal Pap Smear, Cervical Intraepithelial Neoplasia, Cervical Cancer and High Risk HPV for Anogenital Dysplasia ( 30485943 )
2018
34
Profiling of serum antibodies against human papillomavirus antigens in Korean women with cervical intraepithelial neoplasia and cervical cancer. ( 30353680 )
2018
35
Prevalence and Genotype Distribution of Human Papillomavirus in Invasive Cervical Cancer, Cervical Intraepithelial Neoplasia, and Asymptomatic Women in Southeast China. ( 30402468 )
2018
36
In situ expressions of protein 16 (p16CDKN2A) and transforming growth factor beta-1 in patients with cervical intraepithelial neoplasia and cervical cancer. ( 30059872 )
2018
37
Different amplification patterns of 3q26 and 5p15 regions in cervical intraepithelial neoplasia and cervical cancer. ( 30072014 )
2018
38
Cervical intraepithelial neoplasia (CIN) in African women living with HIV: role and effect of rigorous histopathological review by a panel of pathologists in the HARP study endpoint determination. ( 28600294 )
2018
39
Digital Colposcopy With Dynamic Spectral Imaging for Detection of Cervical Intraepithelial Neoplasia 2+ in Low-Grade Referrals: The IMPROVE-COLPO Study. ( 28953107 )
2018
40
Association between grade of referral smear and high-grade disease among women with biopsy samples showing cervical intraepithelial neoplasia grade 2. ( 29049873 )
2018
41
Association Between Passive Smoking and the Risk of Cervical Intraepithelial Neoplasia 1 in Korean Women. ( 29093300 )
2018
42
Association of antiretroviral therapy with high-risk human papillomavirus, cervical intraepithelial neoplasia, and invasive cervical cancer in women living with HIV: a systematic review and meta-analysis. ( 29107561 )
2018
43
High-grade cervical intraepithelial neoplasia in human papillomavirus self-sampling of screening non-attenders. ( 29136403 )
2018
44
Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study. ( 29404740 )
2018
45
Human papilloma virus genotyping for the cross-sectional and longitudinal probability of developing cervical intraepithelial neoplasia grade 2 or more. ( 29453769 )
2018
46
Long-Term Vitamin D Supplementation and the Effects on Recurrence and Metabolic Status of Cervical Intraepithelial Neoplasia Grade 2 or 3: A Randomized, Double-Blind, Placebo-Controlled Trial. ( 29466786 )
2018
47
Management of Early Cervical Stromal Invasion FIGO Stage 1A1 When Margins Are Involved With Cervical Intraepithelial Neoplasia. ( 29474238 )
2018
48
Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis. ( 29487049 )
2018
49
Associations of human gene EPB41L3 DNA methylation and cervical intraepithelial neoplasia in women living with HIV-1 in Africa. ( 30005021 )
2018
50
Conservative management of cervical intraepithelial neoplasia grade 2 (CIN2) in women under 30 years of age: A cohort study. ( 30048921 )
2018

Variations for Cervical Intraepithelial Neoplasia

Expression for Cervical Intraepithelial Neoplasia

Search GEO for disease gene expression data for Cervical Intraepithelial Neoplasia.

Pathways for Cervical Intraepithelial Neoplasia

Pathways related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.07 BIRC5 CDKN2A TERC TERT VEGFC
2 10.83 BIRC5 NME1 ODC1 TERT

GO Terms for Cervical Intraepithelial Neoplasia

Cellular components related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.65 BIRC5 CDC6 CDKN2A FHIT KRT17 KRT8
2 intermediate filament GO:0005882 9.43 KRT17 KRT8 NME1
3 telomerase holoenzyme complex GO:0005697 9.16 TERC TERT
4 telomerase catalytic core complex GO:0000333 8.62 TERC TERT

Biological processes related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA biosynthetic process GO:0071897 9.37 TERC TERT
2 cell cycle GO:0007049 9.35 BIRC5 CDC6 CDKN2A MKI67 RBL1
3 nucleotide metabolic process GO:0009117 9.32 FHIT NME1
4 telomere maintenance via telomerase GO:0007004 9.26 TERC TERT
5 replicative senescence GO:0090399 9.16 CDKN2A TERT
6 negative regulation of cellular senescence GO:2000773 8.8 RBL1 TERC TERT

Molecular functions related to Cervical Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA-directed DNA polymerase activity GO:0003964 9.16 TERC TERT
2 telomerase activity GO:0003720 8.96 TERC TERT
3 telomerase RNA reverse transcriptase activity GO:0003721 8.62 TERC TERT
4 protein binding GO:0005515 10.07 BIRC5 CDC6 CDKN2A FHIT KRT17 KRT8

Sources for Cervical Intraepithelial Neoplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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44 MeSH
45 MESH via Orphanet
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49 NCI
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51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
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74 UMLS via Orphanet
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