MCID: CRV029
MIFTS: 16

Cervical Keratinizing Squamous Cell Carcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Keratinizing Squamous Cell Carcinoma

MalaCards integrated aliases for Cervical Keratinizing Squamous Cell Carcinoma:

Name: Cervical Keratinizing Squamous Cell Carcinoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7483
NCIt 50 C40187
UMLS 70 C1517658

Summaries for Cervical Keratinizing Squamous Cell Carcinoma

Disease Ontology : 12 A cervical squamous cell carcinoma that is characterized by keratin pearls, abundant keratohyaline granules or dense cytoplasmic keratinization.

MalaCards based summary : Cervical Keratinizing Squamous Cell Carcinoma is related to luteoma and skin tag. An important gene associated with Cervical Keratinizing Squamous Cell Carcinoma is ADAR (Adenosine Deaminase RNA Specific), and among its related pathways/superpathways are CCR5 Pathway in Macrophages and MAPK signaling pathway. Related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Related Diseases for Cervical Keratinizing Squamous Cell Carcinoma

Diseases related to Cervical Keratinizing Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 luteoma 9.7 SHBG FGFR2
2 skin tag 9.6 SHBG FGFR2
3 acanthosis nigricans 9.6 SHBG FGFR2
4 cervical non-keratinizing squamous cell carcinoma 9.6 RAP1B PRKACB ADAR
5 acne 9.5 SHBG FGFR2
6 pigmentation disease 9.4 SHBG FGFR2 ADAR

Graphical network of the top 20 diseases related to Cervical Keratinizing Squamous Cell Carcinoma:



Diseases related to Cervical Keratinizing Squamous Cell Carcinoma

Symptoms & Phenotypes for Cervical Keratinizing Squamous Cell Carcinoma

GenomeRNAi Phenotypes related to Cervical Keratinizing Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 8.92 PRKACB
2 Decreased substrate adherent cell growth GR00193-A-2 8.92 FGFR2 PRKACB
3 Decreased substrate adherent cell growth GR00193-A-3 8.92 FGFR2

Drugs & Therapeutics for Cervical Keratinizing Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Keratinizing Squamous Cell Carcinoma

Genetic Tests for Cervical Keratinizing Squamous Cell Carcinoma

Anatomical Context for Cervical Keratinizing Squamous Cell Carcinoma

Publications for Cervical Keratinizing Squamous Cell Carcinoma

Articles related to Cervical Keratinizing Squamous Cell Carcinoma:

# Title Authors PMID Year
1
Expression of fibroblast growth factor receptor 2 IIIc in human uterine cervical intraepithelial neoplasia and cervical cancer. 61
20043066 2010
2
Orbital metastasis of keratinizing squamous cell cervical carcinoma with giant cells. A case report. 61
17975710 2009
3
Establishment and characterization of human uterine cervical epidermoid carcinoma cell line HHUS containing HPV 59 DNA. 61
15859161 2004

Variations for Cervical Keratinizing Squamous Cell Carcinoma

Expression for Cervical Keratinizing Squamous Cell Carcinoma

Search GEO for disease gene expression data for Cervical Keratinizing Squamous Cell Carcinoma.

Pathways for Cervical Keratinizing Squamous Cell Carcinoma

Pathways related to Cervical Keratinizing Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.3 SHBG RAP1B PRKACB
2 12.16 RAP1B PRKACB FGFR2
3
Show member pathways
12.08 RAP1B PRKACB FGFR2
4 11.53 RAP1B PRKACB
5
Show member pathways
11.44 RAP1B PRKACB
6 11.02 RAP1B PRKACB FGFR2
7 10.16 RAP1B PRKACB
8 9.77 RAP1B PRKACB

GO Terms for Cervical Keratinizing Squamous Cell Carcinoma

Sources for Cervical Keratinizing Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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