Cervical Large Cell Neuroendocrine Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cervical Large Cell Neuroendocrine Carcinoma

MalaCards integrated aliases for Cervical Large Cell Neuroendocrine Carcinoma:

Name: Cervical Large Cell Neuroendocrine Carcinoma ¹² ¹⁵ ¹⁷ ⁷²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:6659

NCIt ⁵⁰ C40214

EFO ¹⁷ EFO_1000167

UMLS ⁷² C1516417

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Summaries for Cervical Large Cell Neuroendocrine Carcinoma

Disease Ontology : ¹² A cervix carcinoma that has material basis in neuroendocrine tissue and is characerized by a diffuse, organoid, trabecular, or cord-like pattern of neoplastic cells with abundant cytoplasm, large nuclei, prominent nucleoli, and a high mitotic rate.

MalaCards based summary : Cervical Large Cell Neuroendocrine Carcinoma is related to large cell neuroendocrine carcinoma and cystadenoma. An important gene associated with Cervical Large Cell Neuroendocrine Carcinoma is CHGA (Chromogranin A). Affiliated tissues include cervix.

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Related Diseases for Cervical Large Cell Neuroendocrine Carcinoma

Diseases related to Cervical Large Cell Neuroendocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 110, show less)

#	Related Disease	Score	Top Affiliating Genes
1	large cell neuroendocrine carcinoma	30.4	SYP CHGA
2	cystadenoma	10.3	SYP CHGA
3	ureter small cell carcinoma	10.3	SYP CHGA
4	small cell carcinoma	10.3	SYP CHGA
5	esophageal neuroendocrine tumor	10.3	SYP CHGA
6	urinary bladder small cell neuroendocrine carcinoma	10.3	SYP CHGA
7	ovarian large-cell neuroendocrine carcinoma	10.3	SYP CHGA
8	auditory system cancer	10.3	SYP CHGA
9	acinar cell cystadenocarcinoma	10.3	SYP CHGA
10	primary hepatic neuroendocrine carcinoma	10.3	SYP CHGA
11	cellular ependymoma	10.3	SYP CHGA
12	peritoneal serous adenocarcinoma	10.3	SYP CHGA
13	small cell carcinoma of the bladder	10.3	SYP CHGA
14	chordoid meningioma	10.3	SYP CHGA
15	atypical follicular adenoma	10.3	SYP CHGA
16	gallbladder small cell carcinoma	10.3	SYP CHGA
17	pulmonary large cell neuroendocrine carcinoma	10.3	SYP CHGA
18	olfactory groove meningioma	10.3	SYP CHGA
19	cauda equina neoplasm	10.3	SYP CHGA
20	conventional angiosarcoma	10.3	SYP CHGA
21	pancreatic serous cystadenoma	10.3	SYP CHGA
22	gastric leiomyoma	10.3	GCG CHGA
23	olfactory nerve neoplasm	10.3	SYP CHGA
24	nodular ganglioneuroblastoma	10.2	SYP CHGA
25	autonomic nervous system benign neoplasm	10.2	SYP CHGA
26	pineocytoma	10.2	SYP CHGA
27	pulmonary sclerosing hemangioma	10.2	SYP CHGA
28	sclerosing hemangioma	10.2	SYP CHGA
29	hemangioma	10.2	SYP CHGA
30	subependymoma	10.2	SYP CHGA
31	gastric small cell carcinoma	10.2	SYP CHGA
32	glycogen storage disease vi	10.2	GCG CHGA
33	anterior cranial fossa meningioma	10.2	SYP CHGA
34	respiratory system benign neoplasm	10.2	SYP CHGA
35	gastric squamous cell carcinoma	10.2	SYP CHGA
36	non-functioning pancreatic endocrine tumor	10.2	SYP CHGA
37	papillary ependymoma	10.2	SYP CHGA
38	tanycytic ependymoma	10.2	SYP CHGA
39	pleomorphic xanthoastrocytoma	10.2	SYP CHGA
40	pulmonary blastoma	10.2	SYP CHGA
41	central neurocytoma	10.2	SYP CHGA
42	gastrointestinal neuroendocrine benign tumor	10.2	SST CHGA
43	cervix small cell carcinoma	10.2	SYP CHGA
44	somatostatinoma	10.2	SST CHGA
45	gastric neuroendocrine neoplasm	10.2	SST CHGA
46	horseshoe kidney	10.2	SYP CHGA
47	cerebellar liponeurocytoma	10.2	SYP CHGA
48	pituitary carcinoma	10.2	SST CHGA
49	granulosa cell tumor of the ovary	10.2	SYP CHGA
50	glucagonoma	10.2	SST CHGA
51	cranial nerve malignant neoplasm	10.2	SYP CHGA
52	gastric tubular adenocarcinoma	10.2	SYP CHGA
53	insulinomatosis and diabetes mellitus	10.2	SST CHGA
54	tubular adenocarcinoma	10.2	SYP CHGA
55	olfactory neuroblastoma	10.1	SYP CHGA
56	vipoma	10.1	SST CHGA
57	malignant glandular tumor of peripheral nerve sheath	10.1	SYP SST
58	ganglioneuroma	10.1	SYP CHGA
59	pancreatic somatostatinoma	10.1	SYP SST
60	ganglioglioma	10.1	SYP CHGA
61	duodenal gastrinoma	10.1	SST CHGA
62	gastrinoma	10.1	SST CHGA
63	pancreatic endocrine carcinoma	10.1	SYP SST
64	lung benign neoplasm	10.1	SYP CHGA
65	zollinger-ellison syndrome	10.1	SST CHGA
66	primary pigmented nodular adrenocortical disease	10.1	SYP CHGA
67	pancreatic cholera	10.1	SST GCG
68	dumping syndrome	10.0	SST GCG
69	large cell carcinoma	10.0	SYP CHGA
70	functional colonic disease	10.0	SYP SST
71	islet cell tumor	10.0	SST CHGA
72	serotonin syndrome	10.0	SST CHGA
73	neuroendocrine carcinoma	10.0
74	ectopic cushing syndrome	10.0	SYP SST
75	colonic pseudo-obstruction	10.0	SYP SST
76	atrophic gastritis	10.0	SST CHGA
77	short bowel syndrome	9.9	SST GCG
78	intestinal pseudo-obstruction	9.9	SYP SST
79	adrenocortical carcinoma, hereditary	9.9	SYP CHGA
80	pancreas disease	9.9	SST GCG
81	thyroid carcinoma, familial medullary	9.9	SST CHGA
82	acquired metabolic disease	9.8	SST GCG
83	gastrointestinal stromal tumor	9.8	SYP CHGA
84	meningioma, familial	9.8	SYP SST
85	gastrointestinal neuroendocrine tumor	9.7	SYP SST CHGA
86	neuroendocrine tumor	9.7	SYP SST CHGA
87	pancreatoblastoma	9.7	SYP SST CHGA
88	carcinoid tumors, intestinal	9.7	SYP SST CHGA
89	carcinoid syndrome	9.7	SYP SST CHGA
90	binswanger's disease	9.7	SYP SST CHGA
91	mixed ductal-endocrine carcinoma	9.7	SYP SST CHGA
92	malignant pheochromocytoma	9.7	SYP SST CHGA
93	pheochromocytoma	9.7	SYP SST CHGA
94	endocrine organ benign neoplasm	9.7	SYP SST CHGA
95	cell type benign neoplasm	9.7	SYP SST CHGA
96	merkel cell carcinoma	9.7	SYP SST CHGA
97	paraganglioma	9.7	SYP SST CHGA
98	multiple endocrine neoplasia, type i	9.7	SYP SST CHGA
99	small cell cancer of the lung	9.7	SYP SST CHGA
100	gastrointestinal system disease	9.7	SST GCG
101	thyroid cancer, nonmedullary, 2	9.6	SST CHGA
102	hyperglycemia	9.4	SST GCG
103	glucose metabolism disease	9.4	SST PTPRN GCG
104	diabetes mellitus, insulin-dependent	9.4	SST PTPRN GCG
105	diabetes mellitus	9.3	SST PTPRN GCG
106	endocrine gland cancer	9.2	SYP SST GCG CHGA
107	diabetes mellitus, noninsulin-dependent	9.1	SST PTPRN GCG
108	pancreatic cystadenoma	9.0	SST PTPRN GCG CHGA
109	gastrointestinal system benign neoplasm	9.0	SST PTPRN GCG CHGA
110	insulinoma	9.0	SST PTPRN GCG CHGA

Graphical network of the top 20 diseases related to Cervical Large Cell Neuroendocrine Carcinoma:

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Symptoms & Phenotypes for Cervical Large Cell Neuroendocrine Carcinoma

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Drugs & Therapeutics for Cervical Large Cell Neuroendocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Large Cell Neuroendocrine Carcinoma

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Genetic Tests for Cervical Large Cell Neuroendocrine Carcinoma

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Anatomical Context for Cervical Large Cell Neuroendocrine Carcinoma

MalaCards organs/tissues related to Cervical Large Cell Neuroendocrine Carcinoma:

⁴¹

Cervix

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Publications for Cervical Large Cell Neuroendocrine Carcinoma

Articles related to Cervical Large Cell Neuroendocrine Carcinoma:

(showing 3, show less)

#	Title	Authors	PMID	Year
1	Successful neoadjuvant chemotherapy for large cell neuroendocrine carcinoma of the cervix: A case report. ³⁸	Omori M...Hirata S	24567884	2014
2	Cervical large cell neuroendocrine carcinoma with cytologic presentation: a case report. ³⁸	Niwa K...Hirose Y	21053581	2010
3	Large-cell neuroendocrine carcinoma of the cervix associated with cervical-type invasive adenocarcinoma: a report of case and discussion of histogenesis. ³⁸	Cetiner H...Karateke A	16445674	2006

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Genes for Cervical Large Cell Neuroendocrine Carcinoma

Genes related to Cervical Large Cell Neuroendocrine Carcinoma (0 elite genes):

(showing 5, show less)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CHGA	Chromogranin A	Protein Coding	14.26	DISEASES inferred ¹⁵
2	SYP	Synaptophysin	Protein Coding	14.15	DISEASES inferred ¹⁵
3	SST	Somatostatin	Protein Coding	13.7	DISEASES inferred ¹⁵
4	PTPRN	Protein Tyrosine Phosphatase Receptor Type N	Protein Coding	4.8	DISEASES inferred ¹⁵
5	GCG	Glucagon	Protein Coding	3.52	DISEASES inferred ¹⁵

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Variations for Cervical Large Cell Neuroendocrine Carcinoma

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Expression for Cervical Large Cell Neuroendocrine Carcinoma

Search GEO for disease gene expression data for Cervical Large Cell Neuroendocrine Carcinoma.

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Pathways for Cervical Large Cell Neuroendocrine Carcinoma

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GO Terms for Cervical Large Cell Neuroendocrine Carcinoma

Cellular components related to Cervical Large Cell Neuroendocrine Carcinoma according to GeneCards Suite gene sharing:

(showing 4, show less)

#	Name	GO ID	Score	Top Affiliating Genes
1	cytoplasmic vesicle	GO:0031410	9.33	SYP PTPRN CHGA
2	synaptic vesicle	GO:0008021	9.26	SYP PTPRN
3	secretory granule	GO:0030141	8.96	PTPRN CHGA
4	transport vesicle membrane	GO:0030658	8.62	PTPRN CHGA

Molecular functions related to Cervical Large Cell Neuroendocrine Carcinoma according to GeneCards Suite gene sharing:

(showing 1, show less)

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone activity	GO:0005179	8.62	SST GCG

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Sources for Cervical Large Cell Neuroendocrine Carcinoma

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