MCID: CRV037
MIFTS: 27

Cervical Mucinous Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Mucinous Adenocarcinoma

MalaCards integrated aliases for Cervical Mucinous Adenocarcinoma:

Name: Cervical Mucinous Adenocarcinoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3701
NCIt 51 C36095
UMLS 74 C1332919

Summaries for Cervical Mucinous Adenocarcinoma

Disease Ontology : 12 A cervical adenocarcinoma that derives from mucin producing epithelial cells.

MalaCards based summary : Cervical Mucinous Adenocarcinoma is related to cervical adenoma malignum and villoglandular variant cervical mucinous adenocarcinoma. An important gene associated with Cervical Mucinous Adenocarcinoma is STK11 (Serine/Threonine Kinase 11), and among its related pathways/superpathways are LT-BetaR Pathway and Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins. Affiliated tissues include breast, lung and smooth muscle, and related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Related Diseases for Cervical Mucinous Adenocarcinoma

Diseases related to Cervical Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 cervical adenoma malignum 31.8 CALD1 HMGA2 KRT7 MME STK11
2 villoglandular variant cervical mucinous adenocarcinoma 12.6
3 signet ring cell variant cervical mucinous adenocarcinoma 12.6
4 intestinal variant cervical mucinous adenocarcinoma 12.6
5 endocervical type cervical mucinous adenocarcinoma 12.4
6 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.2 HMGA2 STK11
7 conventional leiomyosarcoma 10.2 CALD1 HMGA2
8 angiomyoma 10.2 CALD1 HMGA2
9 well-differentiated liposarcoma 10.2 HMGA2 KRT7
10 lipoadenoma 10.1 HMGA2 KRT7
11 thymus lipoma 10.1 HMGA2 KRT7
12 epithelial-myoepithelial carcinoma 10.1 HMGA2 KRT7
13 papillary hidradenoma 10.1 MME STK11
14 smooth muscle tumor 10.1 HMGA2 MME
15 immune system organ benign neoplasm 10.1 HMGA2 KRT7
16 pulmonary hemosiderosis 10.1 HMGA2 KRT7
17 gastric tubular adenocarcinoma 10.1 KRT7 MAPK1
18 mixed endometrial stromal and smooth muscle tumor 10.0 CALD1 MME
19 breast myofibroblastoma 10.0 CALD1 MME
20 balloon cell malignant melanoma 10.0 KRT7 MME
21 lung combined type small cell carcinoma 10.0 CALD1 MME
22 clear cell papillary renal cell carcinoma 10.0 KRT7 MME
23 malignant leydig cell tumor 10.0 KRT7 MME
24 bladder lymphoma 10.0 KRT7 MME
25 adenomyoma 10.0 KRT7 MME
26 large cell carcinoma 10.0 KRT7 STK11
27 kidney benign neoplasm 10.0 KRT7 MME
28 endometrial stromal nodule 10.0 CALD1 MME
29 breast adenomyoepithelioma 10.0 KRT7 MME
30 breast myoepithelial neoplasm 10.0 KRT7 MME
31 mucinous tubular and spindle renal cell carcinoma 10.0 KRT7 MME
32 eccrine sweat gland neoplasm 10.0 KRT7 MME
33 infiltrative basal cell carcinoma 10.0 KRT7 MME
34 cystadenofibroma 10.0 KRT7 MME
35 collecting duct carcinoma 10.0 KRT7 MME
36 sarcomatoid squamous cell skin carcinoma 10.0 CALD1 MME
37 renal-hepatic-pancreatic dysplasia 10.0 CALD1 KRT7
38 pancreatic mucinous cystadenoma 10.0 KRT7 MME
39 breast fibroadenoma 10.0 HMGA2 MME
40 cystadenoma 10.0 KRT7 MME
41 cell type benign neoplasm 10.0 HMGA2 KRT7
42 mixed cell type cancer 10.0 KRT7 MME
43 renal oncocytoma 10.0 KRT7 MME
44 oncocytoma 9.9 KRT7 MME
45 ovarian brenner tumor 9.9 KRT7 MME
46 lipoid congenital adrenal hyperplasia 9.9
47 adenocarcinoma 9.9
48 mucinous adenocarcinoma 9.9
49 appendix adenocarcinoma 9.9
50 sarcoma, synovial 9.9 HMGA2 KRT7

Graphical network of the top 20 diseases related to Cervical Mucinous Adenocarcinoma:



Diseases related to Cervical Mucinous Adenocarcinoma

Symptoms & Phenotypes for Cervical Mucinous Adenocarcinoma

GenomeRNAi Phenotypes related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 9.5 MAPK1 STK11
2 Decreased substrate adherent cell growth GR00193-A-2 9.5 MAP2K7
3 Decreased substrate adherent cell growth GR00193-A-3 9.5 MAP2K7 MAPK1 STK11
4 Decreased substrate adherent cell growth GR00193-A-4 9.5 MAPK1
5 Decreased human cytomegalovirus (HCMV) strain AD169 replication GR00248-A 9.33 MAP2K7 MAPK1 STK11
6 Increased viability with 4OH tamoxifen GR00200-A 8.62 MAP2K7 STK11

Drugs & Therapeutics for Cervical Mucinous Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Mucinous Adenocarcinoma

Genetic Tests for Cervical Mucinous Adenocarcinoma

Anatomical Context for Cervical Mucinous Adenocarcinoma

MalaCards organs/tissues related to Cervical Mucinous Adenocarcinoma:

42
Breast, Lung, Smooth Muscle, Skin, Kidney, Heart, Thymus

Publications for Cervical Mucinous Adenocarcinoma

Articles related to Cervical Mucinous Adenocarcinoma:

# Title Authors Year
1
Non-human Papillomavirus Cervical Mucinous Adenocarcinoma in a Phenotypic Male with Congenital Adrenal Hyperplasia. ( 30680268 )
2018

Variations for Cervical Mucinous Adenocarcinoma

Expression for Cervical Mucinous Adenocarcinoma

Search GEO for disease gene expression data for Cervical Mucinous Adenocarcinoma.

Pathways for Cervical Mucinous Adenocarcinoma

Pathways related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.18 MAP2K7 MAPK1
2
Show member pathways
10.71 MAP2K7 MAPK1
3 10.3 MAP2K7 MAPK1
4 9.77 MAP2K7 MAPK1

GO Terms for Cervical Mucinous Adenocarcinoma

Biological processes related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sensory perception of pain GO:0019233 9.37 MAPK1 MME
2 positive regulation of telomerase activity GO:0051973 9.32 MAP2K7 MAPK1
3 positive regulation of telomere maintenance via telomerase GO:0032212 9.26 MAP2K7 MAPK1
4 stress-activated MAPK cascade GO:0051403 9.16 MAP2K7 MAPK1
5 positive regulation of telomere capping GO:1904355 8.96 MAP2K7 MAPK1
6 cellular response to UV-B GO:0071493 8.62 MME STK11

Molecular functions related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein serine/threonine kinase activity GO:0004674 9.13 MAP2K7 MAPK1 STK11
2 MAP kinase kinase activity GO:0004708 8.62 MAP2K7 MAPK1

Sources for Cervical Mucinous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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