MCID: CRV037
MIFTS: 23

Cervical Mucinous Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Mucinous Adenocarcinoma

MalaCards integrated aliases for Cervical Mucinous Adenocarcinoma:

Name: Cervical Mucinous Adenocarcinoma 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:3701
NCIt 50 C36095
UMLS 72 C1332919

Summaries for Cervical Mucinous Adenocarcinoma

Disease Ontology : 12 A cervical adenocarcinoma that derives from mucin producing epithelial cells.

MalaCards based summary : Cervical Mucinous Adenocarcinoma is related to cervical adenoma malignum and villoglandular variant cervical mucinous adenocarcinoma. An important gene associated with Cervical Mucinous Adenocarcinoma is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways are Cytoskeletal Signaling and AMP-activated Protein Kinase (AMPK) Signaling. Related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Related Diseases for Cervical Mucinous Adenocarcinoma

Diseases related to Cervical Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 cervical adenoma malignum 31.6 STK11 MME KRT7 HMGA2 CALD1
2 villoglandular variant cervical mucinous adenocarcinoma 12.7
3 signet ring cell variant cervical mucinous adenocarcinoma 12.7
4 intestinal variant cervical mucinous adenocarcinoma 12.7
5 endocervical type cervical mucinous adenocarcinoma 12.5
6 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.4 STK11 HMGA2
7 well-differentiated liposarcoma 10.4 KRT7 HMGA2
8 lipoadenoma 10.3 KRT7 HMGA2
9 conventional leiomyosarcoma 10.3 HMGA2 CALD1
10 thymus lipoma 10.3 KRT7 HMGA2
11 angiomyoma 10.3 HMGA2 CALD1
12 epithelial-myoepithelial carcinoma 10.3 KRT7 HMGA2
13 immune system organ benign neoplasm 10.3 KRT7 HMGA2
14 smooth muscle tumor 10.2 MME HMGA2
15 pulmonary hemosiderosis 10.2 KRT7 HMGA2
16 gastric tubular adenocarcinoma 10.2 MAPK1 KRT7
17 papillary hidradenoma 10.2 STK11 MME
18 acromesomelic dysplasia, maroteaux type 10.1 MAPK1 MAP2K7
19 balloon cell malignant melanoma 10.1 MME KRT7
20 clear cell papillary renal cell carcinoma 10.1 MME KRT7
21 malignant leydig cell tumor 10.1 MME KRT7
22 adenomyoma 10.1 MME KRT7
23 bladder lymphoma 10.1 MME KRT7
24 kidney benign neoplasm 10.1 MME KRT7
25 mucinous tubular and spindle renal cell carcinoma 10.1 MME KRT7
26 breast myoepithelial neoplasm 10.1 MME KRT7
27 breast adenomyoepithelioma 10.1 MME KRT7
28 mixed endometrial stromal and smooth muscle tumor 10.1 MME CALD1
29 cystadenofibroma 10.1 MME KRT7
30 breast myofibroblastoma 10.1 MME CALD1
31 lung combined type small cell carcinoma 10.1 MME CALD1
32 infiltrative basal cell carcinoma 10.1 MME KRT7
33 eccrine sweat gland neoplasm 10.1 MME KRT7
34 large cell carcinoma 10.1 STK11 KRT7
35 collecting duct carcinoma 10.0 MME KRT7
36 pancreatic mucinous cystadenoma 10.0 MME KRT7
37 endometrial stromal nodule 10.0 MME CALD1
38 cystadenoma 10.0 MME KRT7
39 breast fibroadenoma 10.0 MME HMGA2
40 mixed cell type cancer 10.0 MME KRT7
41 sarcomatoid squamous cell skin carcinoma 10.0 MME CALD1
42 cell type benign neoplasm 10.0 KRT7 HMGA2
43 renal-hepatic-pancreatic dysplasia 10.0 KRT7 CALD1
44 renal oncocytoma 10.0 MME KRT7
45 oncocytoma 9.9 MME KRT7
46 lipoid congenital adrenal hyperplasia 9.9
47 cervical cancer 9.9
48 hypospadias 9.9
49 adenocarcinoma 9.9
50 mucinous adenocarcinoma 9.9

Graphical network of the top 20 diseases related to Cervical Mucinous Adenocarcinoma:



Diseases related to Cervical Mucinous Adenocarcinoma

Symptoms & Phenotypes for Cervical Mucinous Adenocarcinoma

GenomeRNAi Phenotypes related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 9.5 MAPK1 STK11
2 Decreased substrate adherent cell growth GR00193-A-2 9.5 MAP2K7
3 Decreased substrate adherent cell growth GR00193-A-3 9.5 MAP2K7 MAPK1 STK11
4 Decreased substrate adherent cell growth GR00193-A-4 9.5 MAPK1
5 Increased viability with 4OH tamoxifen GR00200-A 8.62 MAP2K7 STK11

Drugs & Therapeutics for Cervical Mucinous Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Mucinous Adenocarcinoma

Genetic Tests for Cervical Mucinous Adenocarcinoma

Anatomical Context for Cervical Mucinous Adenocarcinoma

Publications for Cervical Mucinous Adenocarcinoma

Articles related to Cervical Mucinous Adenocarcinoma:

# Title Authors PMID Year
1
Non-human Papillomavirus Cervical Mucinous Adenocarcinoma in a Phenotypic Male with Congenital Adrenal Hyperplasia. 38
30680268 2018
2
Mutational analysis of the RAS/RAF/MEK/ERK signaling pathway in 260 Han Chinese patients with cervical carcinoma. 38
28781678 2017

Variations for Cervical Mucinous Adenocarcinoma

Expression for Cervical Mucinous Adenocarcinoma

Search GEO for disease gene expression data for Cervical Mucinous Adenocarcinoma.

Pathways for Cervical Mucinous Adenocarcinoma

Pathways related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.99 RAB8A KRT7 CALD1
2
Show member pathways
11.85 STK11 RAB8A MAPK1
3 11.36 STK11 RAB8A MAP2K7
4 10.5 MAPK1 MAP2K7
5 9.77 MAPK1 MAP2K7

GO Terms for Cervical Mucinous Adenocarcinoma

Biological processes related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sensory perception of pain GO:0019233 9.37 MME MAPK1
2 positive regulation of telomere maintenance via telomerase GO:0032212 9.32 MAPK1 MAP2K7
3 positive regulation of telomerase activity GO:0051973 9.26 MAPK1 MAP2K7
4 stress-activated MAPK cascade GO:0051403 9.16 MAPK1 MAP2K7
5 positive regulation of telomere capping GO:1904355 8.96 MAPK1 MAP2K7
6 cellular response to UV-B GO:0071493 8.62 STK11 MME

Molecular functions related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAP kinase kinase activity GO:0004708 8.62 MAPK1 MAP2K7

Sources for Cervical Mucinous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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