MCID: CRV037
MIFTS: 26

Cervical Mucinous Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Mucinous Adenocarcinoma

MalaCards integrated aliases for Cervical Mucinous Adenocarcinoma:

Name: Cervical Mucinous Adenocarcinoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3701
NCIt 50 C36095
UMLS 73 C1332919

Summaries for Cervical Mucinous Adenocarcinoma

Disease Ontology : 12 A cervical adenocarcinoma that derives from mucin producing epithelial cells.

MalaCards based summary : Cervical Mucinous Adenocarcinoma is related to cervical adenoma malignum and signet ring cell variant cervical mucinous adenocarcinoma. An important gene associated with Cervical Mucinous Adenocarcinoma is PMS1 (PMS1 Homolog 1, Mismatch Repair System Component), and among its related pathways/superpathways are Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins and Cellular roles of Anthrax toxin. Affiliated tissues include lung, skin and kidney, and related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Related Diseases for Cervical Mucinous Adenocarcinoma

Diseases related to Cervical Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 cervical adenoma malignum 32.0 CALD1 HMGA2 KRT7 MME PMS1 STK11
2 signet ring cell variant cervical mucinous adenocarcinoma 12.6
3 villoglandular variant cervical mucinous adenocarcinoma 12.6
4 intestinal variant cervical mucinous adenocarcinoma 12.6
5 endocervical type cervical mucinous adenocarcinoma 12.3
6 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.1 HMGA2 STK11
7 cecal benign neoplasm 10.1 KRT7 PMS1
8 conventional leiomyosarcoma 10.1 CALD1 HMGA2
9 angiomyoma 10.1 CALD1 HMGA2
10 well-differentiated liposarcoma 10.1 HMGA2 KRT7
11 lipoadenoma 10.1 HMGA2 KRT7
12 thymus lipoma 10.1 HMGA2 KRT7
13 cecum adenocarcinoma 10.1 KRT7 PMS1
14 epithelial-myoepithelial carcinoma 10.1 HMGA2 KRT7
15 papillary hidradenoma 10.1 MME STK11
16 immune system organ benign neoplasm 10.1 HMGA2 KRT7
17 pulmonary hemosiderosis 10.0 HMGA2 KRT7
18 gastric tubular adenocarcinoma 10.0 KRT7 MAPK1
19 mixed endometrial stromal and smooth muscle tumor 10.0 CALD1 MME
20 breast myofibroblastoma 10.0 CALD1 MME
21 balloon cell malignant melanoma 10.0 KRT7 MME
22 lung combined type small cell carcinoma 10.0 CALD1 MME
23 clear cell papillary renal cell carcinoma 10.0 KRT7 MME
24 malignant leydig cell tumor 10.0 KRT7 MME
25 bladder lymphoma 10.0 KRT7 MME
26 adenomyoma 10.0 KRT7 MME
27 kidney benign neoplasm 10.0 KRT7 MME
28 endometrial stromal nodule 10.0 CALD1 MME
29 breast adenomyoepithelioma 10.0 KRT7 MME
30 breast myoepithelial neoplasm 10.0 KRT7 MME
31 mucinous tubular and spindle renal cell carcinoma 10.0 KRT7 MME
32 eccrine sweat gland neoplasm 10.0 KRT7 MME
33 infiltrative basal cell carcinoma 10.0 KRT7 MME
34 cystadenofibroma 10.0 KRT7 MME
35 collecting duct carcinoma 10.0 KRT7 MME
36 large cell carcinoma 10.0 KRT7 STK11
37 sarcomatoid squamous cell skin carcinoma 10.0 CALD1 MME
38 pancreatic mucinous cystadenoma 10.0 KRT7 MME
39 cystadenoma 10.0 KRT7 MME
40 mixed cell type cancer 10.0 KRT7 MME
41 renal-hepatic-pancreatic dysplasia 10.0 CALD1 KRT7
42 breast fibroadenoma 10.0 HMGA2 MME
43 renal oncocytoma 10.0 KRT7 MME
44 oncocytoma 10.0 KRT7 MME
45 ovarian brenner tumor 9.9 KRT7 MME
46 cell type benign neoplasm 9.9 HMGA2 KRT7
47 acromesomelic dysplasia, maroteaux type 9.9 MAP2K7 MAPK1
48 chromophobe renal cell carcinoma 9.9 KRT7 MME
49 cholangiocarcinoma 9.9 KRT7 MAPK1 MME
50 lung cancer susceptibility 3 9.8 KRT7 MAPK1 STK11

Graphical network of the top 20 diseases related to Cervical Mucinous Adenocarcinoma:



Diseases related to Cervical Mucinous Adenocarcinoma

Symptoms & Phenotypes for Cervical Mucinous Adenocarcinoma

GenomeRNAi Phenotypes related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 9.5 MAPK1 STK11
2 Decreased substrate adherent cell growth GR00193-A-2 9.5 MAP2K7
3 Decreased substrate adherent cell growth GR00193-A-3 9.5 MAP2K7 MAPK1 STK11
4 Decreased substrate adherent cell growth GR00193-A-4 9.5 MAPK1
5 Decreased human cytomegalovirus (HCMV) strain AD169 replication GR00248-A 9.33 MAP2K7 MAPK1 STK11
6 Increased viability with 4OH tamoxifen GR00200-A 8.62 MAP2K7 STK11

MGI Mouse Phenotypes related to Cervical Mucinous Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 MAP2K7 MAPK1 PMS1 STK11

Drugs & Therapeutics for Cervical Mucinous Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Mucinous Adenocarcinoma

Genetic Tests for Cervical Mucinous Adenocarcinoma

Anatomical Context for Cervical Mucinous Adenocarcinoma

MalaCards organs/tissues related to Cervical Mucinous Adenocarcinoma:

41
Lung, Skin, Kidney, Heart, Breast, Smooth Muscle, Thymus

Publications for Cervical Mucinous Adenocarcinoma

Variations for Cervical Mucinous Adenocarcinoma

Expression for Cervical Mucinous Adenocarcinoma

Search GEO for disease gene expression data for Cervical Mucinous Adenocarcinoma.

Pathways for Cervical Mucinous Adenocarcinoma

Pathways related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.71 MAP2K7 MAPK1
2 10.3 MAP2K7 MAPK1
3 9.77 MAP2K7 MAPK1

GO Terms for Cervical Mucinous Adenocarcinoma

Biological processes related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sensory perception of pain GO:0019233 9.37 MAPK1 MME
2 positive regulation of telomerase activity GO:0051973 9.32 MAP2K7 MAPK1
3 positive regulation of telomere maintenance via telomerase GO:0032212 9.26 MAP2K7 MAPK1
4 stress-activated MAPK cascade GO:0051403 9.16 MAP2K7 MAPK1
5 positive regulation of telomere capping GO:1904355 8.96 MAP2K7 MAPK1
6 cellular response to UV-B GO:0071493 8.62 MME STK11

Molecular functions related to Cervical Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAP kinase kinase activity GO:0004708 8.62 MAP2K7 MAPK1

Sources for Cervical Mucinous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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