MCID: CRV067
MIFTS: 23

Cervical Neuroblastoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cervical Neuroblastoma

MalaCards integrated aliases for Cervical Neuroblastoma:

Name: Cervical Neuroblastoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050935

Summaries for Cervical Neuroblastoma

Disease Ontology : 12 An extracranial neuroblastoma that has material basis in immature nerve cells.

MalaCards based summary : Cervical Neuroblastoma is related to ganglioneuroblastoma and neuroblastoma. An important gene associated with Cervical Neuroblastoma is MYCN (MYCN Proto-Oncogene, BHLH Transcription Factor). Affiliated tissues include lung, thyroid and breast, and related phenotypes are behavior/neurological and mortality/aging

Related Diseases for Cervical Neuroblastoma

Diseases related to Cervical Neuroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 ganglioneuroblastoma 29.6 VIP SYP MYCN
2 neuroblastoma 29.3 VIP SYP MYCN EWSR1 CHGA
3 thyroid gland medullary carcinoma 29.2 SYP CHGA
4 bilateral retinoblastoma 10.3 MYOG MYCN
5 desmoplastic infantile ganglioglioma 10.3 SYP MYCN
6 cerebral primitive neuroectodermal tumor 10.3 SYP MYCN
7 frontal lobe neoplasm 10.3 SYP MYCN
8 central nervous system mesenchymal non-meningothelial tumor 10.3 MYOG EWSR1
9 nodular medulloblastoma 10.2 SYP MYCN
10 horner's syndrome 10.2
11 retroperitoneal sarcoma 10.2 MYOG EWSR1
12 myocardium cancer 10.2 SYP MYOG
13 lung combined type small cell carcinoma 10.2 SYP MYOG
14 central nervous system primitive neuroectodermal neoplasm 10.2 SYP MYCN
15 ependymoblastoma 10.2 SYP MYCN
16 large cell medulloblastoma 10.2 SYP MYCN
17 pediatric fibrosarcoma 10.2 MYOG EWSR1
18 medullomyoblastoma 10.2 SYP MYOG
19 rectum neuroendocrine neoplasm 10.2 VIP SYP
20 prostate stromal sarcoma 10.2 SYP MYOG
21 endobronchial leiomyoma 10.2 SYP MYOG
22 supratentorial primitive neuroectodermal tumor 10.2 SYP MYCN
23 vagina sarcoma 10.2 SYP MYOG
24 congenital fibrosarcoma 10.2 MYOG EWSR1
25 cerebrum cancer 10.2 SYP MYCN
26 supratentorial cancer 10.2 SYP MYCN
27 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.1 SYP EWSR1
28 melanotic neuroectodermal tumor 10.1 SYP MYOG
29 extraskeletal ewing sarcoma 10.1 SYP EWSR1
30 endobronchial lipoma 10.1 SYP EWSR1
31 extraosseous chondrosarcoma 10.1 SYP EWSR1
32 epithelioid cell synovial sarcoma 10.1 SYP EWSR1
33 mesenchymal cell neoplasm 10.1 MYOG EWSR1
34 pleomorphic rhabdomyosarcoma 10.0 SYP MYOG
35 embryonal rhabdomyosarcoma 10.0 MYOG MYCN EWSR1
36 richter's syndrome 10.0 MYCN BCR
37 myxoid chondrosarcoma 10.0 SYP EWSR1
38 mesenchymal chondrosarcoma 10.0 SYP MYOG
39 sarcoma, synovial 10.0 MYOG MYCN EWSR1
40 cardiovascular cancer 9.9 SYP MYOG
41 pancreatic cholera 9.9 VIP CHGA
42 adrenal neuroblastoma 9.9 SYP MYCN EWSR1
43 glucagonoma 9.9 VIP CHGA
44 askin's tumor 9.9 SYP MYCN EWSR1
45 intracystic papillary adenoma 9.9 PPP3R1 CHGA
46 gastrinoma 9.9 VIP CHGA
47 clear cell basal cell carcinoma 9.9 MYOG CHGA
48 ewing sarcoma of bone 9.9 EWSR1 CHGA
49 rhabdoid tumor predisposition syndrome 1 9.9 SYP BCR
50 mixed cell type cancer 9.9 SYP MYOG

Graphical network of the top 20 diseases related to Cervical Neuroblastoma:



Diseases related to Cervical Neuroblastoma

Symptoms & Phenotypes for Cervical Neuroblastoma

MGI Mouse Phenotypes related to Cervical Neuroblastoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.76 ADGRV1 AMPH BCR MYCN MYOG PPP3R1
2 mortality/aging MP:0010768 9.56 ADGRV1 AMPH BCR CHGA MYCN MYOG
3 nervous system MP:0003631 9.17 ADGRV1 AMPH BCR CHGA MYCN PPP3R1

Drugs & Therapeutics for Cervical Neuroblastoma

Search Clinical Trials , NIH Clinical Center for Cervical Neuroblastoma

Genetic Tests for Cervical Neuroblastoma

Anatomical Context for Cervical Neuroblastoma

MalaCards organs/tissues related to Cervical Neuroblastoma:

40
Lung, Thyroid, Breast, Prostate, Salivary Gland, Bone, Thymus

Publications for Cervical Neuroblastoma

Articles related to Cervical Neuroblastoma:

(show all 39)
# Title Authors PMID Year
1
A case of Carvajal syndrome associated with cervical neuroblastoma in an 8-year-old girl. 61
30079965 2019
2
A very rare adult case of cervical neuroblastoma. 61
31966735 2017
3
Aggressive cervical neuroblastoma with a rare paraneoplastic syndrome: A therapeutic dilemma. 61
27695211 2016
4
Multidisciplinary management of cervical neuroblastoma in infants. 61
25306308 2014
5
Surgical outcome analysis of paediatric thoracic and cervical neuroblastoma. 61
22011775 2012
6
[A case report on cervical neuroblastoma with ataxia]. 61
21702171 2011
7
Fetal cervical neuroblastoma: prenatal diagnosis. 61
21826149 2011
8
I-123 metaiodobenzylguanidine (MIBG) in sympathetic denervation and reinnervation of salivary glands in a child with cervical neuroblastoma. 61
18287857 2008
9
Retropharyngeal neuroblastoma in a neonate: case report and literature review. 61
17661061 2007
10
Cervical neuroblastoma. 61
23120455 2007
11
Congenital Horner's syndrome associated with cervical neuroblastoma. 61
16595184 2006
12
Clear cell myomelanocytic tumor (PEComa) of the duodenum in a child with a history of neuroblastoma. 61
16253032 2005
13
Pathology quiz case 1. Cervical neuroblastoma (NB). 61
15723954 2005
14
Congenital cervical neuroblastoma. 61
15390353 2004
15
Signaling pathways in retinoid chemoprevention and treatment of cancer. 61
15476854 2004
16
[Cervical neuroblastoma in an infant]. 61
15105902 2004
17
Localized cervical neuroblastoma: prevention of surgical complications. 61
14643482 2003
18
Prenatal presentation of cervical congenital neuroblastoma. 61
12913877 2003
19
Cervical neuroblastoma, stage IV-S. 61
11894520 2001
20
Asymmetric salivary gland 123I-meta-iodobenzylguanidine uptake in a patient with cervical neuroblastoma and Horner syndrome. 61
11260573 2001
21
Pitfalls in the interpretation of MIBG scans in cervical neuroblastoma. 61
10955591 2000
22
[Parapharyngeal tumor in an infant. Cervical neuroblastoma, stage IV]. 61
10525614 1999
23
Does Horner's syndrome in infancy require investigation? 61
9536881 1998
24
Primary cervical neuroblastoma in infants. 61
9262064 1997
25
Intracranial route of a cervical neuroblastoma through skull base foramina. 61
8805602 1996
26
[Experience with a operated cervico-mediastinal neuroblastoma in infant]. 61
8301910 1994
27
Cervical neuroblastoma and multiple endocrine neoplasia type 2a. 61
8095252 1993
28
Cervical neuroblastoma in eleven infants--a tumor with favorable prognosis. Clinical and radiologic (US, CT, MRI) findings. 61
8414748 1993
29
Congenital Horner syndrome associated with non-cervical neuroblastoma. 61
1511796 1992
30
Asymmetry of salivary gland I123 metaiodobenzylguanidine (MIBG) uptake in a patient with cervical neuroblastoma and Horner's syndrome--possible etiologic mechanisms. 61
1508596 1992
31
Congenital cervical neuroblastoma associated with Horner syndrome. 61
3244095 1988
32
Primary cervical neuroblastoma: CT and MR findings. 61
3392281 1988
33
Cervical ganglioneuroblastoma. 61
3572236 1987
34
Primary cervical neuroblastoma in infants. 61
3973490 1985
35
[Cervical neuroblastoma in a newborn infant]. 61
6742642 1984
36
A rational approach to cervical neuroblastoma. 61
7093913 1982
37
Spinal intradural metastases of extraneural origin. 61
7246286 1981
38
Cervical neuroblastoma in childhood--a better prognosis? 61
365410 1978
39
Cervical neurogenic tumors presenting as thoracic apical masses in infants and children. 61
263506 1977

Variations for Cervical Neuroblastoma

Expression for Cervical Neuroblastoma

Search GEO for disease gene expression data for Cervical Neuroblastoma.

Pathways for Cervical Neuroblastoma

GO Terms for Cervical Neuroblastoma

Cellular components related to Cervical Neuroblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 synapse GO:0045202 8.92 SYP BCR AMPH ADGRV1

Biological processes related to Cervical Neuroblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 synaptic vesicle endocytosis GO:0048488 8.62 SYP AMPH

Sources for Cervical Neuroblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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