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MCID: CRV068
MIFTS: 33

Cervical Polyp

Categories: Reproductive diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Cervical Polyp

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MalaCards integrated aliases for Cervical Polyp:

Name: Cervical Polyp 12 15 17 74
Cervix Adenomatous Polyp 74

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:0060325
ICD9CM 36 219
ICD10 34 D26 D26.9
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Summaries for Cervical Polyp

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Disease Ontology : 12 A cervix disease characterized by a benign polyp on the surface of the cervical canal.

MalaCards based summary : Cervical Polyp, also known as cervix adenomatous polyp, is related to botryoid rhabdomyosarcoma and endometrial stromal sarcoma. An important gene associated with Cervical Polyp is DES (Desmin), and among its related pathways/superpathways are Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases and Cytoskeletal Signaling. The drugs acetic acid and Iodine have been mentioned in the context of this disorder. Affiliated tissues include cervix, uterus and lung.

Wikipedia : 77 A cervical polyp is a common benign polyp or tumour on the surface of the cervical canal. They can cause... more...

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Related Diseases for Cervical Polyp

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Diseases related to Cervical Polyp via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 botryoid rhabdomyosarcoma 29.7 ACTC1 DES
2 endometrial stromal sarcoma 29.3 ACTC1 DES
3 cervix disease 11.2
4 chronic intestinal pseudoobstruction 10.1 ACTG2 DES
5 mucinous intrahepatic cholangiocarcinoma 10.1 CDX2 MUC6
6 microcolon 10.1 ACTG2 DES
7 duodenum adenocarcinoma 10.1 CDX2 MUC6
8 appendix disease 10.1 CDX2 MUC6
9 biliary papillomatosis 10.1 CDX2 MUC6
10 superior mesenteric artery syndrome 10.1 CDX2 MUC6
11 endocervical adenocarcinoma 10.1 CDX2 MUC6
12 ovarian mucinous neoplasm 10.1 CDX2 MUC6
13 appendix cancer 10.1 CDX2 MUC6
14 cystic teratoma 10.1 CDX2 MUC6
15 duodenum cancer 10.1 CDX2 MUC6
16 pseudomyxoma peritonei 10.1 CDX2 MUC6
17 gastric tubular adenocarcinoma 10.0 CDX2 MUC6
18 signet ring cell adenocarcinoma 10.0 CDX2 MUC6
19 ampulla of vater cancer 10.0 CDX2 MUC6
20 bronchiolo-alveolar adenocarcinoma 10.0 CDX2 MUC6
21 ovarian fibrothecoma 10.0 ACTC1 DES
22 fibroblastic rheumatism 10.0 ACTC1 DES
23 angiolipoma 10.0 ACTC1 DES
24 cutaneous leiomyosarcoma 10.0 ACTC1 DES
25 leiomyosarcoma 10.0 ACTC1 DES
26 spindle cell lipoma 10.0 ACTC1 DES
27 glomangioma 10.0 ACTC1 DES
28 parachordoma 10.0 ACTC1 DES
29 syringocystadenoma papilliferum 10.0 ACTC1 DES
30 ossifying fibromyxoid tumor 10.0 ACTC1 DES
31 epithelioid leiomyosarcoma 10.0 ACTC1 DES
32 sarcoma 10.0
33 adenosarcoma 10.0
34 rhabdomyosarcoma 10.0
35 benign metastasizing leiomyoma 10.0 ACTC1 DES
36 leiomyoma 10.0 ACTC1 DES
37 non-langerhans-cell histiocytosis 10.0 ACTC1 DES
38 pulmonary vein stenosis 10.0 ACTC1 DES
39 perivascular epithelioid cell tumor 10.0 ACTC1 DES
40 small intestine cancer 10.0 CDX2 MUC6
41 cutaneous fibrous histiocytoma 10.0 ACTC1 DES
42 fibrous histiocytoma 10.0 ACTC1 DES
43 congenital fibrosarcoma 10.0 ACTC1 DES
44 ischemic fasciitis 10.0 ACTC1 DES
45 fasciitis 10.0 ACTC1 DES
46 reticulum cell sarcoma 10.0 ACTC1 DES
47 pseudosarcomatous fibromatosis 10.0 ACTC1 DES
48 fibromatosis 10.0 ACTC1 DES
49 dedifferentiated liposarcoma 10.0 ACTC1 DES
50 glomus tumor 10.0 ACTC1 DES

Graphical network of the top 20 diseases related to Cervical Polyp:



Diseases related to Cervical Polyp
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Symptoms & Phenotypes for Cervical Polyp

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Drugs & Therapeutics for Cervical Polyp

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Drugs for Cervical Polyp (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
acetic acid Approved Not Applicable 64-19-7 176
2
Iodine Approved, Investigational Not Applicable 7553-56-2 807
3
Ethanol Approved Not Applicable 64-17-5 702
4 cadexomer iodine Not Applicable
5
Retinol acetate Not Applicable 127-47-9 10245972
6 Anesthetics Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Diagnosis of Cervical Lesions in Women With Unhealthy Looking Cervix Unknown status NCT03150745 Not Applicable
2 Clinical Parameters Predicting Unsatisfactory Cervicovaginal Cytology in Conventional Smears Completed NCT00985309
3 Hysteroscopic Surgery in Treatment of Intrauterine Abnormalities Recruiting NCT03265301 Not Applicable

Search NIH Clinical Center for Cervical Polyp

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Genetic Tests for Cervical Polyp

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Anatomical Context for Cervical Polyp

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MalaCards organs/tissues related to Cervical Polyp:

42
Cervix, Uterus, Lung, Appendix, Ovary, Smooth Muscle, Small Intestine
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Publications for Cervical Polyp

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Articles related to Cervical Polyp:

(show all 34)
# Title Authors Year
1
Giant cervıcal polyp with mesonephric duct remnants: unusual cause of vaginal bleeding in an adolescent girl. ( 24601846 )
2014
2
Embryonal rhabdomyosarcoma of the cervix presenting as a cervical polyp in a 16-year-old adolescent: a case report. ( 24986146 )
2014
3
Uterine prolapse complicated with a giant cervical polyp. ( 21964209 )
2012
4
Mullerian adenosaroma of the cervix with sarcomatous overgrowth and heterologous elements presenting as a recurrent cervical polyp. ( 22953093 )
2012
5
Presentation of renal cell carcinoma as cervical polyp metastasis. ( 20885169 )
2010
6
Giant cervical polyp: a case report and review of a rare entity. ( 18236053 )
2008
7
Adenoid basal carcinoma arising in the cervical polyp: an immunohistochemical study of stromal cells. ( 17572848 )
2007
8
Uterine epithelioid endometrial stromal sarcoma presenting as a "cervical polyp". ( 15806518 )
2005
9
Large cell lymphoma-like reaction in a cervical polyp. ( 16054203 )
2005
10
Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: a case report and review of the literature. ( 15361219 )
2004
11
Lung cancer metastatic to a cervical polyp. ( 14751133 )
2004
12
Embryonal rhabdomyosarcoma (sarcoma botryoides) of the cervix presenting as a cervical polyp treated with fertility-sparing surgery and adjuvant chemotherapy. ( 15385139 )
2004
13
An intrapartum giant cervical polyp. ( 15570350 )
2004
14
Cervical polyp with eccrine syringofibroadenoma-like features. ( 12605651 )
2003
15
Protruding giant cervical polyp in a young adolescent with a previous rhabdomyosarcoma. ( 12547657 )
2002
16
Sarcoma botyroides-an unusual case of a cervical polyp. ( 15512396 )
1999
17
Adenosarcoma of the uterine cervix presenting as a cervical polyp. ( 9736415 )
1998
18
Giant cervical polyp. ( 9594689 )
1998
19
Atypical cervical polyp with intracytoplasmic inclusions. ( 9643509 )
1998
20
Primary extrarenal Wilms' tumor of the uterus presenting as a cervical polyp. ( 9656126 )
1998
21
Cervical polyp as risk factor for hysteroscopically diagnosed endometrial polyps. ( 9359647 )
1997
22
Serous surface papillary carcinoma of the ovary metastatic to a cervical polyp. A case report. ( 8693902 )
1996
23
Giant cervical polyp. A case report. ( 8866393 )
1996
24
Cervical polyp in the menopause and the need for fractional dilatation and curettage. ( 7493709 )
1995
25
Cervical polyp: evaluation of current treatment. ( 8125411 )
1994
26
Hysteroscopic findings in patients with a cervical polyp. ( 8267062 )
1993
27
Primary malignant lymphoma of the uterus: localization in a cervical polyp. ( 8335140 )
1993
28
Cervical polyp presenting as inevitable abortion. ( 2815311 )
1989
29
Giant cervical polyp. ( 3177535 )
1988
30
Giant cervical polyp due to a foreign body in a 'virgin'. ( 3228410 )
1988
31
Malignant cervical polyp. ( 6845056 )
1983
32
Case for diagnosis: cervical polyp. ( 100736 )
1978
33
The cervical polyp: a new diagnostic and therapeutic approach with CO2 hysteroscopy. ( 637080 )
1978
34
Giant cervical polyp. ( 4682621 )
1973
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Variations for Cervical Polyp

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Expression for Cervical Polyp

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Search GEO for disease gene expression data for Cervical Polyp.
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Pathways for Cervical Polyp

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Pathways related to Cervical Polyp according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases 23
Show member pathways
 11.89 ACTC1 ACTG2 CDX2
2
Cytoskeletal Signaling 4
11.29 ACTC1 ACTG2 DES
3
Striated Muscle Contraction 1 67
11.11 ACTC1 DES
4
Cell adhesion_Cadherin-mediated cell adhesion 23
10.56 ACTC1 ACTG2
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GO Terms for Cervical Polyp

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Cellular components related to Cervical Polyp according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell body GO:0044297 8.96 ACTC1 ACTG2
2 filopodium GO:0030175 8.62 ACTC1 ACTG2

Biological processes related to Cervical Polyp according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle contraction GO:0006936 9.16 ACTG2 DES
2 muscle filament sliding GO:0030049 8.96 ACTC1 DES
3 mesenchyme migration GO:0090131 8.62 ACTC1 ACTG2
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Sources for Cervical Polyp

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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