Cervical Serous Adenocarcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cervical Serous Adenocarcinoma

MalaCards integrated aliases for Cervical Serous Adenocarcinoma:

Name: Cervical Serous Adenocarcinoma ¹² ¹⁵ ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5752

NCIt ⁴⁹ C40201

UMLS ⁷¹ C1516431

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Summaries for Cervical Serous Adenocarcinoma

Disease Ontology : ¹² A cervical adenocarcinoma that derives from epithelial cells originating in glandular tissue forming serous lesions.

MalaCards based summary : Cervical Serous Adenocarcinoma is related to thymus clear cell carcinoma and adult type testicular granulosa cell tumor. An important gene associated with Cervical Serous Adenocarcinoma is MLANA (Melan-A), and among its related pathways/superpathways are NF-kappaB Signaling and Primary Focal Segmental Glomerulosclerosis FSGS. Related phenotype is no phenotypic analysis.

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Related Diseases for Cervical Serous Adenocarcinoma

Diseases related to Cervical Serous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 145)

#	Related Disease	Score	Top Affiliating Genes
1	thymus clear cell carcinoma	10.2	MLANA GATA3
2	adult type testicular granulosa cell tumor	10.2	PGR MLANA
3	microinvasive cervical squamous cell carcinoma	10.1	WT1 GATA3
4	uterus leiomyosarcoma	10.1	PGR MLANA
5	liver leiomyosarcoma	10.1	WT1 GATA3
6	retroperitoneum carcinoma	10.1	WT1 MLANA
7	apocrine adenocarcinoma	10.1	PGR GATA3
8	ovarian seromucinous carcinoma	10.1	WT1 PGR
9	serous cystadenocarcinoma	10.1	WT1 PGR
10	cribriform carcinoma	10.1	PGR GATA3
11	sarcomatoid squamous cell skin carcinoma	10.1	MME MLANA
12	uterus perivascular epithelioid cell tumor	10.1	MME MLANA
13	leiomyomatosis	10.1	WT1 PGR
14	balloon cell malignant melanoma	10.1	MME MLANA
15	hypertrophy of breast	10.1	PGR GATA3
16	endosalpingiosis	10.1	WT1 PGR
17	peritoneal serous adenocarcinoma	10.0	WT1 PGR
18	cervical adenomyoma	10.0	PGR MME
19	adenomyoma	10.0	PGR MME
20	myoma	10.0	PGR MME
21	cervical benign neoplasm	10.0	PGR MME
22	uterine corpus adenosarcoma	10.0	PGR MME
23	adenosarcoma	10.0	PGR MME
24	breast leiomyoma	10.0	PGR MME
25	endometrial serous adenocarcinoma	10.0	WT1 PGR
26	cutaneous fibrous histiocytoma	10.0	MME MLANA
27	female reproductive endometrioid cancer	10.0	WT1 PGR
28	epididymal neoplasm	10.0	WT1 MME
29	adult cystic nephroma	10.0	PGR MME
30	intravenous leiomyomatosis	10.0	PGR MME
31	breast metaplastic carcinoma	10.0	PGR MME
32	cervical polyp	10.0	PGR MME
33	sertoli-leydig cell tumor	10.0	WT1 PGR
34	vulvar leiomyoma	10.0	PGR MME
35	cystadenofibroma	10.0	WT1 MME
36	adenofibroma	10.0	WT1 MME
37	mesenchymal cell neoplasm	10.0	MME MLANA
38	sertoli cell tumor	10.0	WT1 PGR
39	cardiovascular cancer	10.0	MME MLANA
40	breast malignant phyllodes tumor	10.0	PGR MME
41	renal adenoma	10.0	WT1 MME
42	vascular cancer	10.0	MME MLANA
43	breast sarcoma	10.0	PGR MME
44	epididymis adenocarcinoma	10.0	WT1 MME
45	epididymis cancer	10.0	WT1 MME
46	connective tissue benign neoplasm	10.0	MME MLANA
47	cervical adenoma malignum	10.0	PGR MME
48	benign breast phyllodes tumor	10.0	PGR MME
49	bladder clear cell adenocarcinoma	10.0	WT1 MME
50	intraductal breast benign neoplasm	10.0	PGR MME

Graphical network of the top 20 diseases related to Cervical Serous Adenocarcinoma:

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Symptoms & Phenotypes for Cervical Serous Adenocarcinoma

MGI Mouse Phenotypes related to Cervical Serous Adenocarcinoma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	no phenotypic analysis	MP:0003012	8.92	GATA3 MLANA PGR WT1

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Drugs & Therapeutics for Cervical Serous Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Serous Adenocarcinoma

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Genetic Tests for Cervical Serous Adenocarcinoma

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Anatomical Context for Cervical Serous Adenocarcinoma

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Publications for Cervical Serous Adenocarcinoma

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Genes for Cervical Serous Adenocarcinoma

Genes related to Cervical Serous Adenocarcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MLANA	Melan-A	Protein Coding	4.24	DISEASES inferred ¹⁵
2	GATA3	GATA Binding Protein 3	Protein Coding	3.94	DISEASES inferred ¹⁵
3	WT1	WT1 Transcription Factor	Protein Coding	3.86	DISEASES inferred ¹⁵
4	MME	Membrane Metalloendopeptidase	Protein Coding	3.7	DISEASES inferred ¹⁵
5	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	3.43	DISEASES inferred ¹⁵
6	PGR	Progesterone Receptor	Protein Coding	3.38	DISEASES inferred ¹⁵

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Variations for Cervical Serous Adenocarcinoma

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Expression for Cervical Serous Adenocarcinoma

Search GEO for disease gene expression data for Cervical Serous Adenocarcinoma.

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Pathways for Cervical Serous Adenocarcinoma

Pathways related to Cervical Serous Adenocarcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	11.31	MLANA GATA3 CEACAM5
2	Primary Focal Segmental Glomerulosclerosis FSGS ¹	10.82	WT1 MME

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GO Terms for Cervical Serous Adenocarcinoma

Biological processes related to Cervical Serous Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular response to cytokine stimulus	GO:0071345	9.26	MME GATA3
2	positive regulation of pri-miRNA transcription by RNA polymerase II	GO:1902895	9.16	WT1 GATA3
3	kidney development	GO:0001822	9.13	WT1 MME GATA3
4	mesenchymal to epithelial transition	GO:0060231	8.62	WT1 GATA3

Molecular functions related to Cervical Serous Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA-binding transcription activator activity, RNA polymerase II-specific	GO:0001228	9.13	WT1 PGR GATA3
2	zinc ion binding	GO:0008270	8.92	WT1 PGR MME GATA3

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Sources for Cervical Serous Adenocarcinoma

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