MCID: CRV011
MIFTS: 19

Cervical Serous Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Cervical Serous Adenocarcinoma

MalaCards integrated aliases for Cervical Serous Adenocarcinoma:

Name: Cervical Serous Adenocarcinoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5752
NCIt 50 C40201
UMLS 70 C1516431

Summaries for Cervical Serous Adenocarcinoma

Disease Ontology : 12 A cervical adenocarcinoma that derives from epithelial cells originating in glandular tissue forming serous lesions.

MalaCards based summary : Cervical Serous Adenocarcinoma is related to thymus clear cell carcinoma and adult type testicular granulosa cell tumor. An important gene associated with Cervical Serous Adenocarcinoma is MLANA (Melan-A), and among its related pathways/superpathways are NF-kappaB Signaling and Primary Focal Segmental Glomerulosclerosis FSGS. Related phenotype is no phenotypic analysis.

Related Diseases for Cervical Serous Adenocarcinoma

Diseases related to Cervical Serous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 150)
# Related Disease Score Top Affiliating Genes
1 thymus clear cell carcinoma 10.2 MLANA GATA3
2 adult type testicular granulosa cell tumor 10.1 PGR MLANA
3 microinvasive cervical squamous cell carcinoma 10.1 WT1 GATA3
4 bartholin's gland disease 10.1 PGR GATA3
5 uterus leiomyosarcoma 10.1 PGR MLANA
6 uterine corpus sarcoma 10.1 PGR MLANA
7 liver leiomyosarcoma 10.1 WT1 GATA3
8 retroperitoneum carcinoma 10.1 WT1 MLANA
9 apocrine adenocarcinoma 10.1 PGR GATA3
10 breast neuroendocrine neoplasm 10.1 PGR GATA3
11 serous cystadenocarcinoma 10.1 WT1 PGR
12 sarcomatoid squamous cell skin carcinoma 10.1 MME MLANA
13 ovarian seromucinous carcinoma 10.1 WT1 PGR
14 balloon cell malignant melanoma 10.1 MME MLANA
15 uterus perivascular epithelioid cell tumor 10.1 MME MLANA
16 cribriform carcinoma 10.1 PGR GATA3
17 leiomyomatosis 10.1 WT1 PGR
18 endosalpingiosis 10.1 WT1 PGR
19 hypertrophy of breast 10.1 PGR GATA3
20 peritoneal serous adenocarcinoma 10.0 WT1 PGR
21 dopamine beta-hydroxylase deficiency 10.0 WT1 GATA3
22 sarcomatoid mesothelioma 10.0 WT1 GATA3
23 cervical adenomyoma 10.0 PGR MME
24 adenomyoma 10.0 PGR MME
25 cervical benign neoplasm 10.0 PGR MME
26 uterine corpus adenosarcoma 10.0 PGR MME
27 adenosarcoma 10.0 PGR MME
28 breast leiomyoma 10.0 PGR MME
29 perivascular tumor 10.0 MME MLANA
30 adult cystic nephroma 10.0 PGR MME
31 epididymal neoplasm 10.0 WT1 MME
32 endometrial serous adenocarcinoma 10.0 WT1 PGR
33 cervical polyp 10.0 PGR MME
34 intravenous leiomyomatosis 10.0 PGR MME
35 breast metaplastic carcinoma 10.0 PGR MME
36 female reproductive endometrioid cancer 10.0 WT1 PGR
37 vaginal endometrial stromal sarcoma 10.0 PGR MME
38 vulvar leiomyoma 10.0 PGR MME
39 cystadenofibroma 10.0 WT1 MME
40 cutaneous fibrous histiocytoma 10.0 MME MLANA
41 breast sarcoma 10.0 PGR MME
42 breast malignant phyllodes tumor 10.0 PGR MME
43 renal adenoma 10.0 WT1 MME
44 benign breast phyllodes tumor 10.0 PGR MME
45 bladder clear cell adenocarcinoma 10.0 WT1 MME
46 mesenchymal cell neoplasm 10.0 MME MLANA
47 cervical adenoma malignum 10.0 PGR MME
48 sertoli-leydig cell tumor 10.0 WT1 PGR
49 cervical adenosarcoma 10.0 PGR MME
50 epididymis adenocarcinoma 10.0 WT1 MME

Graphical network of the top 20 diseases related to Cervical Serous Adenocarcinoma:



Diseases related to Cervical Serous Adenocarcinoma

Symptoms & Phenotypes for Cervical Serous Adenocarcinoma

MGI Mouse Phenotypes related to Cervical Serous Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 8.92 GATA3 MLANA PGR WT1

Drugs & Therapeutics for Cervical Serous Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Cervical Serous Adenocarcinoma

Genetic Tests for Cervical Serous Adenocarcinoma

Anatomical Context for Cervical Serous Adenocarcinoma

Publications for Cervical Serous Adenocarcinoma

Variations for Cervical Serous Adenocarcinoma

Expression for Cervical Serous Adenocarcinoma

Search GEO for disease gene expression data for Cervical Serous Adenocarcinoma.

Pathways for Cervical Serous Adenocarcinoma

Pathways related to Cervical Serous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.31 MLANA GATA3 CEACAM5
2 10.82 WT1 MME

GO Terms for Cervical Serous Adenocarcinoma

Biological processes related to Cervical Serous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to cytokine stimulus GO:0071345 9.26 MME GATA3
2 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.16 WT1 GATA3
3 kidney development GO:0001822 9.13 WT1 MME GATA3
4 mesenchymal to epithelial transition GO:0060231 8.62 WT1 GATA3

Molecular functions related to Cervical Serous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sequence-specific DNA binding GO:0043565 9.33 WT1 PGR GATA3
2 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.13 WT1 PGR GATA3
3 zinc ion binding GO:0008270 8.92 WT1 PGR MME GATA3

Sources for Cervical Serous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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