MCID: CRV069
MIFTS: 48

Cervix Disease

Categories: Reproductive diseases

Aliases & Classifications for Cervix Disease

MalaCards integrated aliases for Cervix Disease:

Name: Cervix Disease 12 15
Uterine Cervical Diseases 45
Cervix Disorders 44
Cervix Diseases 74

Classifications:



External Ids:

Disease Ontology 12 DOID:2253
MeSH 45 D002577
NCIt 51 C40241
SNOMED-CT 69 63339007
UMLS 74 C0007867

Summaries for Cervix Disease

MedlinePlus : 44 The cervix is the lower part of the uterus, the place where a baby grows during pregnancy. The cervix has a small opening that expands during childbirth. It also allows menstrual blood to leave a woman's body. Your health care provider may perform a Pap test during your health checkup to look for changes to the cells of the cervix, including cervical cancer. Other problems with the cervix include: Cervicitis - inflammation of the cervix. This is usually from an infection. Cervical incompetence - This can happen during pregnancy. The opening of the cervix widens long before the baby is due. Cervical polyps and cysts - abnormal growths on the cervix

MalaCards based summary : Cervix Disease, also known as uterine cervical diseases, is related to cervical polyp and cervicitis, and has symptoms including pelvic pain An important gene associated with Cervix Disease is MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Human cytomegalovirus infection. The drugs Lymecycline and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include cervix, testes and lymph node, and related phenotypes are homeostasis/metabolism and cellular

Disease Ontology : 12 A uterine disease that is located in the cervix.

Wikipedia : 77 The cervix or cervix uteri (Latin: neck of the uterus) is the lower part of the uterus in the human... more...

Related Diseases for Cervix Disease

Diseases related to Cervix Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 cervical polyp 10.9
2 cervicitis 10.9
3 cervix erosion 10.9
4 cervix endometriosis 10.9
5 uterine cervix leukoplakia 10.9
6 cervical incompetence 10.9
7 early invasive cervical adenocarcinoma 10.5 CDKN2A INSM1
8 breast papillomatosis 10.5 CCND1 CDKN2A
9 penile disease 10.5 CDKN2A GP6 TP53
10 megaesophagus 10.5 CDKN2A FHIT TP53
11 anal squamous cell carcinoma 10.5 AKT1 CDKN2A TP53
12 cervical squamous cell carcinoma 10.5 CDH1 CDKN2A TP53
13 microinvasive cervical squamous cell carcinoma 10.5 INSM1 PTPRN
14 keratinizing squamous cell carcinoma 10.5 AKAP13 CDKN2A TP53
15 tongue disease 10.5 CDH1 CDKN2A TP53
16 short-rib thoracic dysplasia 4 with or without polydactyly 10.5 CASP3 TP53
17 tonsil cancer 10.5 CDH1 CDKN2A TP53
18 oral leukoplakia 10.5 CCND1 CDKN2A TP53
19 rare adenocarcinoma of the breast 10.5 AKT1 TP53
20 verrucous carcinoma 10.5 CCND1 CDKN2A TP53
21 barrett's adenocarcinoma 10.5 CDKN2A FHIT TP53
22 cervical adenosarcoma 10.5 GP5 GP6
23 pancreatic ductal carcinoma 10.5 CDKN2A TP53 VEGFA
24 vulvar disease 10.5 CDKN2A GP5 TP53
25 cholecystitis 10.5 CDH1 CDKN2A TP53
26 cerebral convexity meningioma 10.5 CDH1 TP53
27 inverted papilloma 10.5 CCND1 CDKN2A TP53
28 penile cancer 10.4 CCND1 CDKN2A TP53
29 tonsil squamous cell carcinoma 10.4 CCND1 CDKN2A
30 bile duct adenocarcinoma 10.4 AKT1 CDH1 TP53
31 retinal cancer 10.4 CCND1 CDKN2A TP53
32 esophageal disease 10.4 CCND1 CDKN2A TP53
33 anogenital venereal wart 10.4 CDKN2A GP6 TP53 UBE3A
34 skin melanoma 10.4 CASP3 CDKN2A TP53
35 pharynx squamous cell carcinoma 10.4 AKT1 CASP3
36 keratocystic odontogenic tumor 10.4 CCND1 FHIT TP53
37 in situ carcinoma 10.4 CDH1 CDKN2A SERPIND1 TP53
38 bladder squamous cell carcinoma 10.4 CDKN2A TP53
39 suppressor of tumorigenicity 3 10.4 CDKN2A FHIT TP53 UBE3A
40 fallopian tube endometrioid adenocarcinoma 10.4 CDKN2A INSM1 PTPRN
41 peripheral nervous system neoplasm 10.4 AKT1 CASP3 TP53
42 grade iii astrocytoma 10.4 CDKN2A TP53 VEGFA
43 fallopian tube adenocarcinoma 10.4 INSM1 MAPK8IP1 PTPRN
44 ocular cancer 10.4 CCND1 CDKN2A TP53
45 cervix small cell carcinoma 10.4 CDKN2A MAPK8IP1 MAPK8IP2 TP53
46 connective tissue cancer 10.4 AKT1 TP53 VEGFA
47 focal epithelial hyperplasia 10.4 GP5 GP6 TP53
48 serous cystadenocarcinoma 10.4 AKT1 TP53 VEGFA
49 cystadenocarcinoma 10.4 AKT1 TP53 VEGFA
50 infiltrating angiolipoma 10.4 CDKN2A VEGFA

Graphical network of the top 20 diseases related to Cervix Disease:



Diseases related to Cervix Disease

Symptoms & Phenotypes for Cervix Disease

UMLS symptoms related to Cervix Disease:


pelvic pain

MGI Mouse Phenotypes related to Cervix Disease:

47 (show all 17)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.41 AKAP13 AKT1 CASP3 CCND1 CDH1 CDKN2A
2 cellular MP:0005384 10.34 AKT1 CASP3 CCND1 CDH1 CDKN2A INSM1
3 endocrine/exocrine gland MP:0005379 10.34 AKT1 CASP3 CCND1 CDH1 CDKN2A INSM1
4 growth/size/body region MP:0005378 10.32 AKAP13 AKT1 CASP3 CCND1 CDH1 CDKN2A
5 mortality/aging MP:0010768 10.31 AKAP13 AKT1 CASP3 CCND1 CDH1 CDKN2A
6 cardiovascular system MP:0005385 10.27 AKAP13 AKT1 CASP3 CCND1 CDH1 CDKN2A
7 hematopoietic system MP:0005397 10.24 AKAP13 AKT1 CASP3 CCND1 CDKN2A FHIT
8 immune system MP:0005387 10.23 AKAP13 AKT1 CASP3 CCND1 CDH1 CDKN2A
9 integument MP:0010771 10.17 AKT1 CASP3 CCND1 CDH1 CDKN2A FHIT
10 digestive/alimentary MP:0005381 10.14 CASP3 CCND1 CDH1 CDKN2A FHIT INSM1
11 craniofacial MP:0005382 10.09 AKAP13 CASP3 CCND1 INSM1 PAX1 TP53
12 nervous system MP:0003631 10.03 AKAP13 AKT1 CASP3 CCND1 CDKN2A INSM1
13 muscle MP:0005369 9.97 AKAP13 AKT1 CASP3 CDKN2A PAX1 SERPIND1
14 neoplasm MP:0002006 9.87 AKT1 CCND1 CDH1 CDKN2A FHIT TP53
15 reproductive system MP:0005389 9.77 AKAP13 AKT1 CASP3 CCND1 CDH1 CDKN2A
16 no phenotypic analysis MP:0003012 9.76 CASP3 CDH1 CDKN2A INSM1 MAPK8IP2 TP53
17 respiratory system MP:0005388 9.17 AKT1 CASP3 CCND1 CDKN2A INSM1 TP53

Drugs & Therapeutics for Cervix Disease

Drugs for Cervix Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 457)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lymecycline Approved, Investigational Phase 4 992-21-2 5280963
2
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
3
Azithromycin Approved Phase 4,Phase 3 83905-01-5 447043 55185
4
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
5
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 15663-27-1 2767 441203 84093
6
Procaine Approved, Investigational, Vet_approved Phase 4 59-46-1 4914
7
Bupivacaine Approved, Investigational Phase 4,Not Applicable 38396-39-3, 2180-92-9 2474
8
Chloroprocaine Approved Phase 4 133-16-4 8612
9
Bupropion Approved Phase 4,Phase 2 34841-39-9, 34911-55-2 444
10
Dopamine Approved Phase 4,Phase 2,Not Applicable 62-31-7, 51-61-6 681
11
Nicotine Approved Phase 4,Not Applicable 54-11-5 89594 942
12
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
13
Iron Approved, Experimental Phase 4,Phase 1,Phase 2 7439-89-6, 15438-31-0 27284 23925
14
Ferrous fumarate Approved Phase 4 141-01-5
15
Vitamin C Approved, Nutraceutical Phase 4,Phase 2 50-81-7 54670067 5785
16 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
17 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
18 Antimalarials Phase 4,Phase 1
19 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
20 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
21 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
22 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
23 Liver Extracts Phase 4,Phase 2,Phase 1,Not Applicable
24 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
25 Anesthetics Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
26 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
27 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
28 Psychotropic Drugs Phase 4,Phase 3,Phase 2
29 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
30 Hematinics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31 Epoetin alfa Phase 4,Phase 3 113427-24-0
32 Analgesics Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
33 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 Fluorodeoxyglucose F18 Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Nutrients Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Anesthetics, Local Phase 4,Phase 3,Phase 2,Not Applicable
39
Apatinib Phase 4,Phase 2,Not Applicable 811803-05-1
40 Protein Kinase Inhibitors Phase 4,Phase 2,Phase 1,Not Applicable
41 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 2
42 Dopamine Uptake Inhibitors Phase 4,Phase 2,Not Applicable
43 Antidepressive Agents, Second-Generation Phase 4,Phase 2
44 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2
45 Dopamine Agents Phase 4,Phase 2,Not Applicable
46 Antidepressive Agents Phase 4,Phase 2
47 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2,Not Applicable
48 Autonomic Agents Phase 4,Phase 2,Phase 3,Not Applicable
49 Cholinergic Agents Phase 4,Not Applicable
50 Central Nervous System Stimulants Phase 4,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1155)
# Name Status NCT ID Phase Drugs
1 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Unknown status NCT02629510 Phase 4 Tachosil
2 Can Alternative Treatment Have an Impact on Cervical Dysplasia? Unknown status NCT00842738 Phase 4
3 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4 Azithromycin;Doxycycline;lymecycline
4 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
5 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
6 Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage Completed NCT03305575 Phase 4 Chloroprocaine;Bupivacaine
7 Application of Tachosil During Lymphadenectomy Completed NCT03752606 Phase 4
8 The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies. Completed NCT03384511 Phase 4 Apatinib
9 Comparing Health Services Interventions for the Prevention of HPV-related Cancer Completed NCT02837926 Phase 4
10 Effect of HPV Vaccination on Women Aged 25 Years Completed NCT02296255 Phase 4
11 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed NCT01544478 Phase 4
12 Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls Completed NCT01173900 Phase 4
13 Management of Cervical Intraepithelial Neoplasia Grade 2 Completed NCT00733109 Phase 4
14 Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease Completed NCT01034358 Phase 4
15 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
16 Patient Navigation in the Safety Net:CONNECTeDD Completed NCT00613275 Phase 4
17 Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking Completed NCT00666978 Phase 4 bupropion hydrochloride
18 Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking Completed NCT00365508 Phase 4 nicotine lozenge;nicotine patch
19 Epoetin Beta in Treating Anemia in Patients With Cervical Cancer Completed NCT00046969 Phase 4 cisplatin
20 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal) Recruiting NCT02862912 Phase 4 Chloroprocaine;Bupivacaine;Fentanyl;Saline
21 Pilot Study to Assess the Potential Clinical Utility of 18F Fluciclovine PET for Cervical and Endometrial Cancer. Recruiting NCT03423082 Phase 4 18F fluciclovine
22 Evaluation of Fluciclovine Uptake in Patients With Cervical, Ovarian Epithelial or Endometrial Cancers. Recruiting NCT03349463 Phase 4 Fluciclovine F18
23 Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines Recruiting NCT03180034 Phase 4
24 HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions Recruiting NCT03051516 Phase 4
25 CervIcal Cancer Screening Trial by Randomization of HPV Testing Intervention for Upcoming Screening (CITRUS Study) Active, not recruiting NCT01895517 Phase 4
26 Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates. Active, not recruiting NCT01953107 Phase 4
27 Trial of Two Versus Three Doses of Human Papillomavirus (HPV) Vaccine in India Active, not recruiting NCT00923702 Phase 4
28 Effectiveness of Cervical Screening in HPV Vaccinated Women Enrolling by invitation NCT02149030 Phase 4
29 To Evaluate the Efficacy and Safety of PEG-rhG-CSF(Jinyouli®) in Reducing Neutropenia in Patients With Cervical Cancer Not yet recruiting NCT03206684 Phase 4 PEG-rhG-CSF;rhG-CSF
30 A Study to Assess the Safety and Reactogenicity of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (Cervarix) in Healthy Female Filipino Subjects Vaccinated According to the Prescribing Information From the Age of 10 Years Onwards. Terminated NCT00730847 Phase 4
31 Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved Communities Terminated NCT00629993 Phase 4
32 IT-system Development for Reaching Cervix Cancer Screening Non-attenders Unknown status NCT02750124 Phase 2, Phase 3
33 Evaluation of TRANSKRIP ® Plus Chemotherapy in Recurrent-Persistent Cervical Cancer Unknown status NCT02446652 Phase 3 Hydralazine/Magnesium;Placebo;Carboplatin;Paclitaxel
34 Adjuvant Chemotherapy for Locally Advanced Cervical Cancer Unknown status NCT02036164 Phase 3 Cisplatin;Paclitaxel;Carboplatin
35 Evaluation of Postoperative Radiotherapy and Concurrent Chemotherapy Effectiveness in Cervical Cancer Unknown status NCT01999933 Phase 2, Phase 3 cisplatin(DDP) weekly;docetaxel plus cisplatin;docetaxel plus cisplatin
36 Study on Early Stage Bulky Cervical Cancers Unknown status NCT01917695 Phase 3 Chemotherapy
37 Postoperative Chemoradiation v.s Radiotherapy for Lymph Node Negative Cervical Cancer Patients Unknown status NCT01756170 Phase 3 paclitaxel;cisplatin
38 Trial of Postoperative Chemoradiotherapy With or Without Consolidation Chemotherapy for Cervical Cancer Patients Unknown status NCT01755845 Phase 3 paclitaxel;cisplatin
39 Study on Paclitaxel Plus Topotecan in Comparison With Topotecan Plus Cisplatin in Recurrent or Persistent Cervical Carcinoma Unknown status NCT01405235 Phase 3 Paclitaxel;Cisplatin/Paclitaxel
40 Comparing Study Between Concurrent Chemoradiation and New Combination Treatment in Cervical Cancer Patients Unknown status NCT01000415 Phase 3
41 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
42 Cisplatin Based Chemoradiation v.s Radiotherapy for Cervical Cancer and With Clinically Defined Good Prognosis Unknown status NCT00846508 Phase 3 Cisplatin
43 Radiotherapy With Single-Agent Cisplatin or Combination Chemotherapy in Defined Poor-Prognostic Cervical Cancer Unknown status NCT00842660 Phase 3 Gemzar (gemcitabine)
44 The Assessment of Preoperative Psychological Intervention on Stress in Women With Gynecological Malignancies Unknown status NCT00726635 Phase 3
45 Randomized Trial Between Weekly and 5 Day 3 Weekly Cisplatin for Cervical Cancer Unknown status NCT00548821 Phase 3 Cisplatin
46 Hydralazine Valproate for Cervical Cancer Unknown status NCT00532818 Phase 3 Hydralazine and magnesium valproate;Placebo
47 Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome Unknown status NCT00348738 Phase 3 Erythropoietin
48 Usefulness of FDG-PET for Advanced Cervical Cancer Unknown status NCT00146458 Phase 3
49 Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients Unknown status NCT00122746 Phase 3
50 The IMAP Study Improving Management of Mildly Abnormal Pap Smears Unknown status NCT00119509 Phase 3

Search NIH Clinical Center for Cervix Disease

Cochrane evidence based reviews: uterine cervical diseases

Genetic Tests for Cervix Disease

Anatomical Context for Cervix Disease

MalaCards organs/tissues related to Cervix Disease:

42
Cervix, Testes, Lymph Node, Breast, Uterus, T Cells, Lung

The Foundational Model of Anatomy Ontology organs/tissues related to Cervix Disease:

20
The Cervix

Publications for Cervix Disease

Variations for Cervix Disease

Expression for Cervix Disease

Search GEO for disease gene expression data for Cervix Disease.

Pathways for Cervix Disease

Pathways related to Cervix Disease according to GeneCards Suite gene sharing:

(show all 45)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.95 AKT1 CASP3 CCND1 TP53 UBE3A VEGFA
2
Show member pathways
12.89 AKAP13 AKT1 CASP3 CCND1 CDKN2A TP53
3
Show member pathways
12.75 AKT1 CASP3 CCND1 CDH1 CDKN2A TP53
4
Show member pathways
12.73 AKT1 CCND1 CDH1 CDKN2A TP53
5 12.68 AKT1 CASP3 MAPK8IP1 MAPK8IP2 TP53 VEGFA
6 12.67 AKT1 CASP3 CCND1 CDH1 CDKN2A TP53
7
Show member pathways
12.55 AKT1 CCND1 TP53 VEGFA
8
Show member pathways
12.51 AKT1 CCND1 CDH1 CDKN2A FHIT TP53
9
Show member pathways
12.48 AKT1 CASP3 CCND1 CDH1 TP53
10 12.47 CASP3 CCND1 CDKN2A TP53 VEGFA
11 12.39 AKT1 CCND1 CDH1 TP53
12
Show member pathways
12.35 CASP3 CCND1 CDKN2A TP53
13 12.34 CCND1 CDH1 CDKN2A TP53
14 12.32 AKT1 CCND1 CDKN2A TP53
15
Show member pathways
12.22 AKT1 CASP3 TP53 VEGFA
16 12.21 AKT1 CASP3 CCND1 TP53 VEGFA
17
Show member pathways
12.2 AKT1 CASP3 CCND1 TP53
18 12.2 CASP3 CCND1 CDKN2A TP53 UBE3A
19
Show member pathways
12.17 AKT1 CASP3 CCND1 TP53
20 12.12 AKT1 CCND1 CDKN2A TP53
21 12.1 AKT1 CASP3 CCND1 TP53
22 12.01 CDKN2A TP53 UBE3A VEGFA
23 11.94 AKT1 CCND1 CDKN2A TP53
24 11.93 AKT1 CCND1 TP53 VEGFA
25 11.9 AKT1 CCND1 CDKN2A TP53
26 11.85 AKT1 CASP3 CCND1 CDH1 TP53 VEGFA
27 11.83 AKT1 CASP3 CCND1 VEGFA
28 11.82 AKT1 CCND1 UBE3A
29
Show member pathways
11.71 AKT1 CDKN2A TP53
30 11.69 AKT1 CASP3 CCND1 FHIT TP53
31
Show member pathways
11.66 AKT1 CASP3 TP53
32 11.65 AKT1 CCND1 UBE3A
33 11.65 CDKN2A TP53 UBE3A VEGFA
34 11.64 AKT1 CASP3 CDKN2A TP53
35 11.62 AKT1 CASP3 CCND1 CDH1 TP53 VEGFA
36 11.59 AKT1 CASP3 VEGFA
37 11.58 AKT1 CCND1 UBE3A
38 11.55 CDKN2A TP53 VEGFA
39 11.52 CCND1 CDKN2A TP53
40 11.52 CCND1 CDH1 CDKN2A TP53 VEGFA
41 11.47 AKT1 CASP3 CCND1 TP53
42 11.44 AKT1 CASP3 TP53
43 11.28 AKT1 CCND1 CDH1
44 10.8 GP5 GP6
45 10.73 AKT1 CASP3 CCND1 TP53 VEGFA

GO Terms for Cervix Disease

Biological processes related to Cervix Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.91 AKT1 CDKN2A PAX1 PTPRN TP53 UBE3A
2 positive regulation of apoptotic process GO:0043065 9.65 AKAP13 AKT1 CASP3 CDKN2A TP53
3 hemostasis GO:0007599 9.5 GP5 GP6 SERPIND1
4 striated muscle cell differentiation GO:0051146 9.46 AKT1 CASP3
5 replicative senescence GO:0090399 9.43 CDKN2A TP53
6 mitotic G1 DNA damage checkpoint GO:0031571 9.4 CCND1 TP53
7 response to organic substance GO:0010033 9.26 AKT1 CASP3 CCND1 CDH1
8 response to UV-A GO:0070141 9.16 AKT1 CCND1
9 cytokine-mediated signaling pathway GO:0019221 9.1 AKT1 CASP3 CCND1 PTPRN TP53 VEGFA

Molecular functions related to Cervix Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 9.43 AKT1 CCND1 CDKN2A MAPK8IP1 MAPK8IP2 TP53
2 GTPase activating protein binding GO:0032794 9.26 AKT1 CDH1
3 cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861 9.16 CASP3 CDKN2A
4 MAP-kinase scaffold activity GO:0005078 8.8 AKAP13 MAPK8IP1 MAPK8IP2

Sources for Cervix Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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