Aliases & Classifications for Cervix Disease

MalaCards integrated aliases for Cervix Disease:

Name: Cervix Disease 12 15
Uterine Cervical Diseases 44
Cervix Disorders 43
Cervix Diseases 73

Classifications:



External Ids:

Disease Ontology 12 DOID:2253
MeSH 44 D002577
NCIt 50 C40241
UMLS 73 C0007867

Summaries for Cervix Disease

MedlinePlus : 43 The cervix is the lower part of the uterus, the place where a baby grows during pregnancy. The cervix has a small opening that expands during childbirth. It also allows menstrual blood to leave a woman's body. Your health care provider may perform a Pap test during your health checkup to look for changes to the cells of the cervix, including cervical cancer. Other problems with the cervix include: Cervicitis - inflammation of the cervix. This is usually from an infection. Cervical incompetence - This can happen during pregnancy. The opening of the cervix widens long before the baby is due. Cervical polyps and cysts - abnormal growths on the cervix

MalaCards based summary : Cervix Disease, also known as uterine cervical diseases, is related to cervicitis and cervical polyp, and has symptoms including pelvic pain An important gene associated with Cervix Disease is MT-TG (Mitochondrially Encoded TRNA Glycine). The drugs Azithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include cervix, testes and lymph node.

Related Diseases for Cervix Disease

Diseases related to Cervix Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 cervicitis 27.8 CD79A CDKN2A FLNA MRAP MT-TG SERPIND1
2 cervical polyp 10.8
3 cervical incompetence 10.8
4 mite infestation 10.7 CD79A FLNA
5 punctate palmoplantar keratoderma 10.7 FLNA MRAP
6 selective igg deficiency disease 10.6 CD40LG CD79A
7 c1q nephropathy 10.6 CD40LG CD79A
8 meningovascular neurosyphilis 10.6 CD40LG CD79A
9 alpha chain disease 10.6 CD40LG CD79A
10 brill-zinsser disease 10.6 CD40LG CD79A
11 cork-handlers' disease 10.6 CD40LG CD79A
12 salpingo-oophoritis 10.6 CD40LG CD79A
13 early yaws 10.6 CD40LG CD79A
14 ventilation pneumonitis 10.6 CD40LG CD79A
15 chronic interstitial cystitis 10.6 CD40LG CD79A
16 axillary adenitis 10.6 CD40LG CD79A
17 cryofibrinogenemia 10.6 CD40LG CD79A
18 trichostrongyloidiasis 10.6 CD40LG CD79A
19 subacute bacterial endocarditis 10.6 CD40LG CD79A
20 heterophyiasis 10.6 CD40LG CD79A
21 immunoglobulin g deficiency 10.6 CD40LG CD79A
22 orbital granuloma 10.6 CD40LG CD79A
23 transient hypogammaglobulinemia of infancy 10.6 CD40LG CD79A
24 hyperglobulinemic purpura 10.6 CD40LG CD79A
25 chronic orbital inflammation 10.6 CD79A MRAP
26 gastroduodenitis 10.5 CD40LG CD79A
27 bacterial conjunctivitis 10.5 CD40LG CD79A
28 heavy chain disease 10.5 CD40LG CD79A
29 ophthalmia neonatorum 10.5 CD40LG CD79A
30 immunoglobulin a deficiency 1 10.5 CD40LG CD79A
31 parotid disease 10.5 CD40LG CD79A
32 cerebral arteritis 10.5 CD40LG CD79A
33 selective immunoglobulin deficiency disease 10.5 CD40LG CD79A
34 geniculate herpes zoster 10.5 CD40LG CD79A
35 sporotrichosis 10.5 CD40LG CD79A
36 fallopian tube disease 10.5 CD40LG CD79A
37 hyperimmunoglobulin syndrome 10.5 CD40LG CD79A
38 congenital syphilis 10.5 CD40LG CD79A
39 polyclonal hypergammaglobulinemia 10.5 CD40LG CD79A
40 monoclonal paraproteinemia 10.5 CD40LG CD79A
41 salpingitis 10.5 CD40LG CD79A
42 ocular toxoplasmosis 10.5 CD40LG CD79A
43 balanoposthitis 10.5 CDKN2A GP6
44 dysgammaglobulinemia 10.5 CD40LG CD79A
45 congenital hypogammaglobulinemia 10.5 CD40LG CD79A
46 acute maxillary sinusitis 10.5 CD40LG CD79A
47 myasthenic syndrome, congenital, 10 10.5 CD40LG MT-TG
48 chronic polyneuropathy 10.5 CD40LG CD79A
49 spinocerebellar ataxia, autosomal recessive 10 10.5 CD40LG CD79A
50 parasitic ichthyosporea infectious disease 10.5 CD40LG CD79A

Graphical network of the top 20 diseases related to Cervix Disease:



Diseases related to Cervix Disease

Symptoms & Phenotypes for Cervix Disease

UMLS symptoms related to Cervix Disease:


pelvic pain

Drugs & Therapeutics for Cervix Disease

Drugs for Cervix Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 425)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
2
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
3
Lymecycline Approved, Investigational Phase 4 992-21-2 5280963
4
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
5
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 15663-27-1 84093 441203 2767
6
Bupropion Approved Phase 4,Phase 2 34841-39-9, 34911-55-2 444
7
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
8
Nicotine Approved Phase 4,Not Applicable 54-11-5 942 89594
9
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
10
Iron Approved Phase 4,Phase 1,Phase 2 7439-89-6 23925
11
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
12
Chloroprocaine Approved Phase 4 133-16-4 8612
13
Procaine Approved, Investigational, Vet_approved Phase 4 59-46-1 4914
14
Vitamin C Approved, Nutraceutical Phase 4,Phase 2 50-81-7 5785 54670067
15 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
16 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
17 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
18 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
19 Antimalarials Phase 4,Phase 1
20 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
21 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
22 Liver Extracts Phase 4,Phase 2,Phase 1,Not Applicable
23 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
24 Psychotropic Drugs Phase 4,Phase 3,Phase 2
25 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
26 Epoetin alfa Phase 4,Phase 3 113427-24-0
27 Hematinics Phase 4,Phase 3,Phase 2,Phase 1
28 Anesthetics Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
29 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
30 Analgesics Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
31 Fluorodeoxyglucose F18 Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Antidepressive Agents Phase 4,Phase 2
33 Antidepressive Agents, Second-Generation Phase 4,Phase 2
34 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 2
35 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2
36 Dopamine Agents Phase 4,Phase 2
37 Dopamine Uptake Inhibitors Phase 4,Phase 2
38 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2
39 Autonomic Agents Phase 4,Phase 3,Phase 2,Not Applicable
40 Central Nervous System Stimulants Phase 4,Phase 2,Not Applicable
41 Cholinergic Agents Phase 4,Not Applicable
42 Nicotinic Agonists Phase 4,Not Applicable
43 Anesthetics, Local Phase 4,Phase 3,Phase 2,Not Applicable
44 Adjuvants, Anesthesia Phase 4
45 Analgesics, Opioid Phase 4,Not Applicable
46 Anesthetics, General Phase 4,Not Applicable
47 Anesthetics, Intravenous Phase 4,Not Applicable
48 Narcotics Phase 4,Not Applicable,Early Phase 1
49 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1045)
# Name Status NCT ID Phase Drugs
1 Comparing Health Services Interventions for the Prevention of HPV-related Cancer Unknown status NCT02837926 Phase 4
2 Can Alternative Treatment Have an Impact on Cervical Dysplasia? Unknown status NCT00842738 Phase 4
3 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4 Azithromycin;Doxycycline;lymecycline
4 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
5 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
6 The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies. Completed NCT03384511 Phase 4 Apatinib
7 Effect of HPV Vaccination on Women Aged 25 Years Completed NCT02296255 Phase 4
8 Comparing the Rate of Insufficient Cells for Diagnosis Between Surepath® and Conventional Smear in Women After Radiation Therapy for Cervical Cancer Completed NCT01988376 Phase 4
9 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) Completed NCT01544478 Phase 4
10 Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls Completed NCT01173900 Phase 4
11 Management of Cervical Intraepithelial Neoplasia Grade 2 Completed NCT00733109 Phase 4
12 Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease Completed NCT01034358 Phase 4
13 Alternate Dosing Schedules Study for HPV Vaccine Completed NCT00862810 Phase 4
14 Patient Navigation in the Safety Net:CONNECTeDD Completed NCT00613275 Phase 4
15 Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking Completed NCT00666978 Phase 4 bupropion hydrochloride
16 Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking Completed NCT00365508 Phase 4 nicotine lozenge;nicotine patch
17 Epoetin Beta in Treating Anemia in Patients With Cervical Cancer Completed NCT00046969 Phase 4 cisplatin
18 Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage Recruiting NCT03305575 Phase 4 Chloroprocaine;Bupivacaine
19 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal) Recruiting NCT02862912 Phase 4 Chloroprocaine;Bupivacaine;Fentanyl;Saline
20 Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV Vaccines Recruiting NCT03180034 Phase 4
21 HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions Recruiting NCT03051516 Phase 4
22 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Active, not recruiting NCT02629510 Phase 4 Tachosil
23 CervIcal Cancer Screening Trial by Randomization of HPV Testing Intervention for Upcoming Screening (CITRUS Study) Active, not recruiting NCT01895517 Phase 4
24 Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates. Active, not recruiting NCT01953107 Phase 4
25 Trial of Two Versus Three Doses of Human Papillomavirus (HPV) Vaccine in India Active, not recruiting NCT00923702 Phase 4
26 Effectiveness of Cervical Screening in HPV Vaccinated Women Enrolling by invitation NCT02149030 Phase 4
27 Pilot Study to Assess the Potential Clinical Utility of 18F Fluciclovine PET for Cervical and Endometrial Cancer. Not yet recruiting NCT03423082 Phase 4 18F fluciclovine
28 Evaluation of Fluciclovine Uptake in Patients With Cervical, Ovarian Epithelial or Endometrial Cancers. Not yet recruiting NCT03349463 Phase 4 Fluciclovine F18
29 To Evaluate the Efficacy and Safety of PEG-rhG-CSF(Jinyouli®) in Reducing Neutropenia in Patients With Cervical Cancer Not yet recruiting NCT03206684 Phase 4 PEG-rhG-CSF;rhG-CSF
30 A Study to Assess the Safety and Reactogenicity of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (Cervarix) in Healthy Female Filipino Subjects Vaccinated According to the Prescribing Information From the Age of 10 Years Onwards. Terminated NCT00730847 Phase 4
31 Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved Communities Terminated NCT00629993 Phase 4
32 IT-system Development for Reaching Cervix Cancer Screening Non-attenders Unknown status NCT02750124 Phase 2, Phase 3
33 Postoperative Chemoradiation v.s Radiotherapy for Lymph Node Negative Cervical Cancer Patients Unknown status NCT01756170 Phase 3 paclitaxel;cisplatin
34 Trial of Postoperative Chemoradiotherapy With or Without Consolidation Chemotherapy for Cervical Cancer Patients Unknown status NCT01755845 Phase 3 paclitaxel;cisplatin
35 Study With Intensity Modulated Radiation Therapy With Cisplatin to Treat Stage I-IVA Cervical Cancer Unknown status NCT01554397 Phase 2, Phase 3 Cisplatin
36 Study on Paclitaxel Plus Topotecan in Comparison With Topotecan Plus Cisplatin in Recurrent or Persistent Cervical Carcinoma Unknown status NCT01405235 Phase 3 Paclitaxel;Cisplatin/Paclitaxel
37 Comparing Study Between Concurrent Chemoradiation and New Combination Treatment in Cervical Cancer Patients Unknown status NCT01000415 Phase 3
38 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
39 Cisplatin Based Chemoradiation v.s Radiotherapy for Cervical Cancer and With Clinically Defined Good Prognosis Unknown status NCT00846508 Phase 3 Cisplatin
40 Radiotherapy With Single-Agent Cisplatin or Combination Chemotherapy in Defined Poor-Prognostic Cervical Cancer Unknown status NCT00842660 Phase 3 Gemzar (gemcitabine)
41 The Assessment of Preoperative Psychological Intervention on Stress in Women With Gynecological Malignancies Unknown status NCT00726635 Phase 3
42 Randomized Trial Between Weekly and 5 Day 3 Weekly Cisplatin for Cervical Cancer Unknown status NCT00548821 Phase 3 Cisplatin
43 Hydralazine Valproate for Cervical Cancer Unknown status NCT00532818 Phase 3 Hydralazine and magnesium valproate;Placebo
44 Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome Unknown status NCT00348738 Phase 3 Erythropoietin
45 Usefulness of FDG-PET for Advanced Cervical Cancer Unknown status NCT00146458 Phase 3
46 Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients Unknown status NCT00122746 Phase 3
47 The IMAP Study Improving Management of Mildly Abnormal Pap Smears Unknown status NCT00119509 Phase 3
48 Immunogenicity Bridge Between an Investigational Monovalent Vaccine and the Equivalent Component of Gardasil (V501) a Quadrivalent Vaccine (V501-012)(COMPLETED) Completed NCT00092482 Phase 3
49 Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System Completed NCT00973362 Phase 3
50 Noncarious Cervical Lesion Treatment Outcomes Completed NCT00867997 Phase 3

Search NIH Clinical Center for Cervix Disease

Cochrane evidence based reviews: uterine cervical diseases

Genetic Tests for Cervix Disease

Anatomical Context for Cervix Disease

MalaCards organs/tissues related to Cervix Disease:

41
Cervix, Testes, Lymph Node, Breast, T Cells, Uterus, Prostate

Publications for Cervix Disease

Articles related to Cervix Disease:

# Title Authors Year
1
Association of KIR genes and HLA-C alleles with HPV-related uterine cervical disease in Korean women. ( 23398510 )
2013

Variations for Cervix Disease

Expression for Cervix Disease

Search GEO for disease gene expression data for Cervix Disease.

Pathways for Cervix Disease

GO Terms for Cervix Disease

Biological processes related to Cervix Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 8.96 CD40LG CD79A
2 platelet activation GO:0030168 8.8 CD40LG FLNA GP6

Sources for Cervix Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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