Cervix Small Cell Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: CRV022 MIFTS: 36	Cervix Small Cell Carcinoma Categories: Cancer diseases, Reproductive diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Cervix Small Cell Carcinoma

MalaCards integrated aliases for Cervix Small Cell Carcinoma:

Name: Cervix Small Cell Carcinoma ¹² ¹⁵

Small Cell Carcinoma of the Cervix ¹² ⁷³

Small Cell Carcinoma of the Cervix Uteri ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:6740

NCIt ⁵⁰ C7982

UMLS ⁷³ C0279674

Sources

Summaries for Cervix Small Cell Carcinoma

MalaCards based summary : Cervix Small Cell Carcinoma, also known as small cell carcinoma of the cervix, is related to small cell carcinoma and extraosseous chondrosarcoma. An important gene associated with Cervix Small Cell Carcinoma is ENO2 (Enolase 2), and among its related pathways/superpathways are ERK Signaling and Adhesion. The drugs Cisplatin and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include cervix, ovary and lung, and related phenotypes are behavior/neurological and growth/size/body region

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Related Diseases for Cervix Small Cell Carcinoma

Diseases related to Cervix Small Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)

#	Related Disease	Score	Top Affiliating Genes
1	small cell carcinoma	30.3	CDKN2A CHGA ENO2 NCAM1 SYP TP53
2	extraosseous chondrosarcoma	10.3	ENO2 SYP
3	subependymal glioma	10.3	ENO2 SYP
4	pineal gland cancer	10.3	ENO2 SYP
5	clear cell ependymoma	10.3	ENO2 SYP
6	astroblastoma	10.3	ENO2 SYP
7	goblet cell carcinoid	10.3	CHGA ENO2
8	middle cerebral artery infarction	10.3	ENO2 NCAM1
9	chordoid meningioma	10.3	CHGA SYP
10	supratentorial primitive neuroectodermal tumor	10.3	NCAM1 SYP
11	hypoganglionosis	10.3	NCAM1 SYP
12	endocervical carcinoma	10.3	CDKN2A MAPK8IP1
13	sella turcica neoplasm	10.3	POMC SYP
14	tuberculum sellae meningioma	10.3	POMC SYP
15	carotid body cancer	10.3	ENO2 SYP
16	pituitary carcinoma	10.3	CHGA POMC
17	ureter small cell carcinoma	10.3	CHGA SYP
18	malignant sertoli cell tumor	10.3	ENO2 SYP
19	intracranial primitive neuroectodermal tumor	10.3	CHGA ENO2
20	multiple mucosal neuroma	10.3	ENO2 NCAM1
21	sinonasal undifferentiated carcinoma	10.3	ENO2 SYP
22	vulvar disease	10.3	CDKN2A TP53
23	vulva squamous cell carcinoma	10.3	CDKN2A TP53
24	scrotal carcinoma	10.3	CDKN2A TP53
25	lung meningioma	10.3	ENO2 NCAM1
26	nasal cavity adenocarcinoma	10.3	CDKN2A TP53
27	bartholin's gland disease	10.3	CDKN2A TP53
28	bladder carcinoma in situ	10.3	CDKN2A TP53
29	spitz nevus	10.3	CDKN2A TP53
30	adenoma of the pancreas	10.3	CHGA SYP
31	acinar cell cystadenocarcinoma	10.3	CHGA SYP
32	lung combined type small cell carcinoma	10.3	NCAM1 SYP
33	pancreatic somatostatinoma	10.2	ENO2 SYP
34	peritoneal serous adenocarcinoma	10.2	CHGA SYP
35	primary hepatic neuroendocrine carcinoma	10.2	CHGA SYP
36	urinary bladder small cell neuroendocrine carcinoma	10.2	CHGA ENO2 SYP
37	auditory system cancer	10.2	CHGA ENO2 SYP
38	papillary tumor of the pineal region	10.2	ENO2 SYP
39	small cell carcinoma of the bladder	10.2	CHGA ENO2 SYP
40	pulmonary large cell neuroendocrine carcinoma	10.2	CHGA ENO2 SYP
41	inappropriate adh syndrome	10.2	AVP POMC
42	cauda equina neoplasm	10.2	CHGA ENO2 SYP
43	microcystic meningioma	10.2	CDH17 ENO2
44	autonomic nervous system benign neoplasm	10.2	CHGA ENO2 SYP
45	nodular ganglioneuroblastoma	10.2	CHGA ENO2 SYP
46	choriocarcinoma of ovary	10.2	ENO2 NCAM1
47	pineocytoma	10.2	CHGA ENO2 SYP
48	ovarian serous adenofibroma	10.2	NCAM1 POMC
49	cutaneous ganglioneuroma	10.2	ENO2 NCAM1 SYP
50	extrahepatic bile duct adenocarcinoma	10.2	ENO2 NCAM1 SYP

Graphical network of the top 20 diseases related to Cervix Small Cell Carcinoma:

Sources

Symptoms & Phenotypes for Cervix Small Cell Carcinoma

MGI Mouse Phenotypes related to Cervix Small Cell Carcinoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	10.02	AVP CDKN2A ENO2 MAPK8IP1 MAPK8IP2 NCAM1
2	growth/size/body region	MP:0005378	9.96	CDH2 CDKN2A CHGA CXCR2 ENO2 MAPK8IP1
3	homeostasis/metabolism	MP:0005376	9.9	AVP CDH2 CDKN2A CHGA CNN1 CXCR2
4	mortality/aging	MP:0010768	9.73	AVP CDH2 CDKN2A CHGA CNN1 CXCR2
5	nervous system	MP:0003631	9.44	AVP CDH2 CDKN2A CHGA CXCR2 ENO2

Sources

Drugs & Therapeutics for Cervix Small Cell Carcinoma

Drugs for Cervix Small Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 33)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Cisplatin

Approved

Phase 2,Phase 1

15663-27-1

2767 441203 84093

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatine

cisplatino

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

Paclitaxel

Approved, Vet_approved

Phase 2,Phase 1

33069-62-4

36314

Synonyms:

(2AR-(2aalpha,4b,4abeta,6b,9a(a r*,betas*),11a,12a,12balpha))-b-(benzoylamino)-a-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4b,4abeta,6b,9a(a r*,betas*),11a,12a,12balpha))-b-(benzoylamino)-a-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4β,4abeta,6β,9α(α r*,betas*),11α,12α,12balpha))-β-(benzoylamino)-α-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4β,4abeta,6β,9α(α r*,betas*),11α,12α,12balpha))-β-(benzoylamino)-α-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

157069-30-2

33069-62-4

5b,20-Epoxy-1,2-a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5b,20-Epoxy-1,2-a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5β,20-epoxy-1,2-α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5β,20-epoxy-1,2-α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

7 Epi taxol

7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.

7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.

7-epi-Paclitaxel

7-Epipaclitaxel

7-Epi-paclitaxel

7-epi-Taxol

7-Epitaxol

7-Epi-taxol

AB00513812

ABI 007

abi-007

ABI007

ABI-007

Abraxane

Abraxane (TN)

Abraxane I.V. Suspension

Abraxis BioScience brand of albumin-bound paclitaxel

AC1L1IOG

AC1L1VJI

AC1L9AVF

AC-675

ACon1_002231

albumin-bound paclitaxel

Ambotz33069-62-4

ANX-513

Anzatax

Asotax

BIDD:PXR0046

Bio-0076

Bio1_000362

Bio1_000851

Bio1_001340

Bio2_000416

Bio2_000896

BMS 181339-01

BMS-181339

BMS-181339-01

BPBio1_000320

BRD-A23723433-001-01-2

BRD-A28746609-001-04-0

BRD-K62008436-001-03-1

Bris taxol

Bristaxol

BSPBio_000290

BSPBio_001152

BSPBio_002614

C07394

C466458

C47H51NO14

Capxol

CCRIS 8143

CHEBI:103439

CHEBI:45863

CHEMBL100910

CHEMBL418410

CHEMBL48

CID36314

CID441276

CID4666

CID6713921

CID6915727

cMAP_000068

CPD-8718

D00491

DB01229

DHP-107

DHP-208

DivK1c_000441

DRG-0190

DTS-301

Ebetaxel

EmPAC

Epitaxol

EU-0101201

Genaxol

Genetaxyl

Genexol

Genexol-PM

HMS1362J13

HMS1568O12

HMS1792J13

HMS1922K08

HMS1990J13

HMS2090D07

HMS2093K15

HMS501G03

HSDB 6839

I06-0014

IDI1_000441

IDI1_002171

Intaxel

KBio1_000441

KBio2_000492

KBio2_002016

KBio2_002509

KBio2_003060

KBio2_004584

KBio2_005077

KBio2_005628

KBio2_007152

KBio2_007645

KBio3_000903

KBio3_000904

KBio3_001834

KBio3_002987

KBioGR_000492

KBioGR_001893

KBioGR_002509

KBioSS_000492

KBioSS_002016

KBioSS_002517

LipoPac

LMPR0104390001

Lopac0_001201

LS-31070

MBT 0206

MEGxp0_001940

Micellar Paclitaxel

Mitotax

MLS000863266

MLS001077297

MLS002154218

MLS002172439

MLS002695976

MolPort-001-742-627

MolPort-003-665-783

MolPort-003-932-365

MPI-5018

nab-paclitaxel

Nanotaxel

NCGC00024995-02

NCGC00024995-03

NCGC00024995-04

NCGC00024995-05

NCGC00024995-06

NCGC00024995-07

NCGC00164367-01

NCGC00164367-02

NCGC00164367-03

nchembio.188-comp1

nchembio.2007.34-comp9

nchembio.215-comp9

nchembio853-comp6

NCI60_000601

Neuro_000060

NINDS_000441

NK 105

Nova-12005

NP-010981

NSC 125973

NSC125973

NSC-125973

NSC358882

OAS-PAC-100

OncoGel

Onxal

Onxol

Onxol, Taxol, Nov-Onxol, Paclitaxel

P1632

Paclical

Pacligel

paclitaxel

Paclitaxel

Paclitaxel (JAN/USP)

Paclitaxel (JAN/USP/INN)

Paclitaxel (Taxol)

Paclitaxel [USAN:INN:BAN]

Paclitaxel, (4 alpha)-isomer

Paxceed

Paxene

Paxoral

Plaxicel

Praxel

Prestwick0_000155

Prestwick1_000155

Prestwick2_000155

Prestwick3_000155

Probes2_000350

QW 8184

S1150_Selleck

S-8184 Paclitaxel Injectable Emulsion

SDCCGMLS-0066823.P001

SDP-013

SMP1_000228

SMR000394086

SMR000857385

SPBio_000943

SPBio_002229

Spectrum_001536

SPECTRUM1503908

Spectrum2_000872

Spectrum3_001057

Spectrum4_001197

Spectrum5_001491

ST50306996

T 7402

T1912_SIGMA

T7191_SIGMA

T7402_SIGMA

TA1

TaxAlbin

Taxol

TAXOL

TAXOL (TN)

Taxol a

Taxol A

Taxol Konzentrat

TAXOL, 10-EPI,

Taxol, bris

Taxol.RTM. (Registered Trademark)

TXL

UNII-P88XT4IS4D

UPCMLD-DP108:001

UPCMLD-DP108:002

Vascular Wrap

weekly paclitaxel

Xorane

Yewtaxan

Topotecan

Approved, Investigational

Phase 2

123948-87-8, 119413-54-6

60700

Synonyms:

(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

(S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione

(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione

(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE

123948-87-8

9 Dimethylaminomethyl 10 hydroxycamptothecin

9-[(dimethylamino)Methyl]-10-hydroxy-(4S)-camptothecin

9-Dimethylaminomethyl-10-hydroxycamptothecin

AC-11592

AC1L1TQZ

AC1Q6APZ

BSPBio_002348

C11158

C23H23N3O5

CCRIS 8163

CHEBI:107501

CHEBI:46035

CHEMBL84

CID60700

D08618

DB01030

HMS2090B20

HSCI1_000228

Hycamptamine

Hycamptin

Hycamtamine

Hycamtin

Hycamtin (TN)

Hydrochloride, nogitecan

Hydrochloride, topotecan

LS-127395

MLS000759456

NCGC00178695-01

NChemBio.2007.10-comp24

NCI60_004771

NCIStruc1_001659

NCIStruc2_001796

Nogitecan hydrochloride

NSC609699

SK And F 104864 a

SK And F104864a

SK And F-104864-a

SK&F-104864-A

SKF 104864

SKF-104864-A

SKF-S 104864

SmithKline beecham brand OF topotecan hydrochloride

SMP2_000312

SMP2_000327

SMR000466344

TOPO

topotecan

Topotecan (BAN)

Topotecan [INN:BAN]

Topotecan Hcl

Topotecan hydrochloride

Topotecan Hydrochloride

Topotecan lactone

Topotecan Lactone

Topotecan monohydrochloride, (S)-isomer

Topotecan Monohydrochloride, (S)-Isomer

TOPOTECAN, HYCAMTIN

Topotecane

Topotecane [INN-French]

Topotecanum

Topotecanum [INN-Latin]

TPT

TTC

UNII-7M7YKX2N15

Lenograstim

Approved, Investigational

Phase 2

135968-09-1

Cetuximab

Approved

Phase 2,Phase 1

205923-56-4

56842117 2333

Synonyms:

205923-56-4

Anti EGFR

cetuximab

Cetuximab

Cétuximab

Cetuximab (genetical recombination)

Cetuximab (genetical recombination) (JAN)

Cetuximab (USAN/INN)

Cetuximabum

D03455

Erbitux

Erbitux (TN)

IMC-C225

Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer

Veliparib

Investigational

Phase 2

912444-00-9

11960529

Antibodies, Monoclonal

Phase 2

Antibodies

Phase 2

Immunoglobulins

Phase 2

Immunologic Factors

Phase 2,Phase 1

Antineoplastic Agents, Phytogenic

Phase 2,Phase 1

Albumin-Bound Paclitaxel

Phase 2,Phase 1

Antimitotic Agents

Phase 2,Phase 1

Adjuvants, Immunologic

Phase 2

Topoisomerase Inhibitors

Phase 2

Poly(ADP-ribose) Polymerase Inhibitors

Phase 2

topoisomerase I inhibitors

Phase 2

Radiopharmaceuticals

Phase 1, Phase 2

Fluorodeoxyglucose F18

Phase 1, Phase 2

Gemcitabine

Approved

Phase 1

95058-81-4

60750

Synonyms:

103882-84-4

122111-03-9

2',2'-DFDC

2',2'-DiF-dC

2',2'-difluoro-2'-Deoxycytidine

2',2'-Difluoro-2'-deoxycytidine

2',2'-Difluorodeoxycytidine

2'-Deoxy-.beta.-D-2',2'-difluorocytidine

2'-Deoxy-2',2'-difluorocytidine

2'-Deoxy-2',2''-difluorocytidine-5'-O-monophosphate

2'-Deoxy-2'-difluorocytidine

4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,4R,5R)-3,3-difluoro-4-Hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one

95058-81-4

AB1004842

AC1L1TUQ

C07650

CCRIS 8984

CHEBI:175901

CHEMBL888

CID60750

Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine

D02368

DB00441

DDFC

DFdC

DFDC

DFdCyd

Folfugem

Gamcitabine

Gemcel

Gemcin

Gemcitabin

Gemcitabina

Gemcitabina [INN-Spanish]

gemcitabine

Gemcitabine

Gemcitabine (USAN/INN)

Gemcitabine HCl

Gemcitabine hydrochloride

Gemcitabine stereoisomer

Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer

Gemcitabine, (beta-D-threo-pentafuranosyl)-isomer

Gemcitabine, (D-threo-pentafuranosyl)-isomer

Gemcitabinum

Gemcitabinum [INN-Latin]

GemLip

Gemtro

Gemzar

Gemzar (hydrochloride)

GEO

HMS2089P10

HSDB 7567

Inno-D07001

LS-59139

LY 188011

LY188011

LY-188011

NCGC00168784-01

NChemBio.2007.10-comp25

nchembio.573-comp7

nchembio.90-comp2

NSC 613327

NSC613327

TL8005979

UNII-B76N6SBZ8R

Zefei

ZINC18279854

Antiviral Agents

Phase 1

Immunosuppressive Agents

Phase 1

Antimetabolites, Antineoplastic

Phase 1

Antimetabolites

Phase 1

Anti-Infective Agents

Phase 1

Formaldehyde

Approved, Vet_approved

50-00-0

712

Synonyms:

Aldeide formica

Fannoform

Formaldehyd

Formaldehyde solution

Formalin

FORMALIN

Formalina

Formaline

Formalith

Formic aldehyde

Formol

Methaldehyde

Methanal

Methyl aldehyde

Methylene glycol

Methylene oxide

Oxomethane

Oxomethylene

Oxymethylene

Paraform

Paraformaldehyde

Krestin

Radiation-Protective Agents

Anti-Bacterial Agents

Antibiotics, Antitubercular

interferons

Protective Agents

Interferon Inducers

Interventional clinical trials:

(show all 14)

#	Name	Status	NCT ID	Phase	Drugs
1	Panitumumab, Cisplatin, and Pelvic Radiation Therapy in Treating Patients With Stage IB, Stage II, or Stage III Cervical Cancer	Unknown status	NCT01158248	Phase 2	cisplatin
2	ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer	Completed	NCT00309959	Phase 2	Paclitaxel Albumin-Stabilized Nanoparticle Formulation
3	Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer	Completed	NCT00217633	Phase 2
4	Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer	Completed	NCT01266447	Phase 2	Topotecan Hydrochloride;Veliparib
5	Fludeoxyglucose (FDG) F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer	Completed	NCT00416455	Phase 1, Phase 2	ferumoxtran-10
6	Cetuximab and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer	Completed	NCT00101192	Phase 2	cisplatin
7	Paclitaxel, Topotecan, and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer	Completed	NCT00276796	Phase 2	cisplatin;paclitaxel;topotecan hydrochloride
8	Radiation Therapy Plus Paclitaxel and Cisplatin in Treating Patients With Cervical Cancer	Completed	NCT00003379	Phase 1, Phase 2	cisplatin;paclitaxel
9	ADXS11-001 High Dose HPV+ Cervical Cancer	Active, not recruiting	NCT02164461	Phase 1, Phase 2
10	Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer	Completed	NCT00104910	Phase 1	Cisplatin
11	Radiation Therapy Plus Cisplatin and Gemcitabine in Treating Patients With Cervical Cancer	Completed	NCT00068549	Phase 1	Gemcitabine Hydrochloride;Cisplatin
12	Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes	Completed	NCT00460356
13	Collecting Tumor Samples From Patients With Gynecological Tumors	Completed	NCT00897442
14	Use of Social Networking to Survey Women With Small and Large Cell Carcinomas of the Cervix	Recruiting	NCT01606293

Search NIH Clinical Center for Cervix Small Cell Carcinoma

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Genetic Tests for Cervix Small Cell Carcinoma

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Anatomical Context for Cervix Small Cell Carcinoma

MalaCards organs/tissues related to Cervix Small Cell Carcinoma:

⁴¹

Cervix, Ovary, Lung, Tongue, Pancreas, Thyroid, Pineal

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Publications for Cervix Small Cell Carcinoma

Articles related to Cervix Small Cell Carcinoma:

(show all 48)

#	Title	Authors	Year
1	Advanced small cell carcinoma of the cervix - Successful treatment with concurrent etoposide and cisplatin chemotherapy and extended field radiation: A case report and discussion. ( 29255785 )	Bajaj A....Small W.	2018
2	Lambert-Eaton Myasthenic Syndrome Associated with Synchronous Double Cancer: A Combination of Small Cell Carcinoma of the Cervix and Breast Carcinoma. ( 29526952 )		2018
3	Influence of clinicopathological characteristics and comprehensive treatment models on the prognosis of small cell carcinoma of the cervix: A systematic review and meta-analysis. ( 29641578 )	Zhang Q...Li L	2018
4	The local treatment modalities in FIGO stage I-II small-cell carcinoma of the cervix are determined by disease stage and lymph node status. ( 26990881 )	Zhou J....Guo Z.W.	2016
5	Prognostic value of lymph node ratio in patients with small-cell carcinoma of the cervix based on data from a large national registry. ( 26730205 )	Zhou J...He ZY	2016
6	Prognostic risk factors for small cell carcinoma of the cervix and impact of platinum-based neoadjuvant chemotherapy. ( 25890393 )		2015
7	Adenocarcinoma of the cervix associated with a neuroendocrine small cell carcinoma of the cervix in the spectrum of Muir-Torre syndrome. ( 26050364 )		2015
8	Metastatic small cell carcinoma of the cervix to the oral cavity: A rare case report and an insight into pathogenesis of metastasis. ( 26604504 )	Mallikarjun JH...Patil ST	2015
9	Gynecologic Cancer InterGroup (GCIG) Consensus Review for Small Cell Carcinoma of the Cervix. ( 25341572 )	Satoh T....Fujiwara K.	2014
10	Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix. ( 25408479 )	Nakajima A....Inoue M.	2014
11	Metastatic small-cell carcinoma of the cervix during pregnancy. ( 24456456 )	Canto MJ...Ojeda F	2014
12	Small cell carcinoma of the cervix at 32-week gestation: a case report and review of the literature. ( 24719986 )	Liu H...Liu X	2014
13	Small cell carcinoma of the cervix in liquid-based Pap test: utilization of split-sample immunocytochemical and molecular analysis. ( 20891001 )	Giorgadze T....Husain M.	2012
14	Chromogranin A (CgA) as poor prognostic factor in patients with small cell carcinoma of the cervix: results of a retrospective study of 293 patients. ( 22529895 )		2012
15	Downregulation of six microRNAs is associated with advanced stage, lymph node metastasis and poor prognosis in small cell carcinoma of the cervix. ( 22438992 )		2012
16	Small cell carcinoma of the cervix: treatment and survival outcomes of 188 patients. ( 20579961 )	Cohen J.G....Chan J.K.	2010
17	Clinicopathological features and prognosis of small cell carcinoma of the cervix. ( 21063846 )		2010
18	Small-cell carcinoma of the cervix at 23 weeks gestation. ( 20385993 )		2010
19	Incidence, mortality, and prognostic factors of small cell carcinoma of the cervix. ( 18515524 )	Chen J....Gaffney D.K.	2008
20	Small cell carcinoma of the cervix presenting with acute vaginal hemorrhage: a case report. ( 18455059 )		2008
21	Small cell carcinoma of the cervix: a case report. ( 17828547 )	Korcum AF...Simsek T	2008
22	Neuroendocrine small cell carcinoma of the cervix associated with endocervical adenocarcinoma: a case report. ( 17718130 )	Alphandery C....Pilotti S.	2007
23	Small-cell carcinoma of the cervix: fourteen years of experience at a single institution using a combined-modality regimen of involved-field irradiation and platinum-based combination chemotherapy. ( 12972526 )	Hoskins PJ...Lee N	2003
24	Small cell carcinoma of the cervix: a clinicopathologic and immunohistochemical study of 23 cases. ( 12478483 )		2002
25	Predictors of outcome in small cell carcinoma of the cervix--a case series. ( 11606074 )	Straughn JM...Barnes MN	2001
26	Small cell carcinoma of the cervix complicated by pregnancy. ( 10378639 )	Leung TW...O SK	1999
27	Hypoglycemia due to an insulin-secreting small-cell carcinoma of the cervix. ( 10471459 )	Seckl MJ...Seckl JR	1999
28	Treatment resistant small cell carcinoma of the cervix. ( 10575314 )	McGarry RC...Seemayer TA	1999
29	Small cell carcinoma of the cervix: analysis of clinical and pathological findings. ( 9611065 )	Wang PH...Yu KJ	1998
30	Small cell carcinoma of the cervix: a clinical study of 15 patients and review of the literature. ( 10838295 )	Weed JC...Tawfik O	1998
31	Small-Cell Carcinoma of the Cervix Presenting with Severe Hypokalemia as a Manifestation of Cushing's Syndrome. ( 25951213 )	Barnes MN...Kilgore LC	1997
32	Efficacy of radical hysterectomy as treatment for patients with small cell carcinoma of the cervix. ( 8608533 )	Sevin BU...Averette HA	1996
33	Small cell carcinoma of the cervix of neuroendocrine origin causing obstructed labour. ( 8775261 )	Perrin L...Ward B	1996
34	Successful treatment of neuroendocrine small cell carcinoma of the cervix metastatic to regional lymph nodes. ( 8812543 )	Kim YB...Karlan BY	1996
35	Small cell carcinoma of the cervix. ( 8859607 )	Sheridan E...Coleman RE	1996
36	Adjuvant chemotherapy in stage IB neuroendocrine small cell carcinoma of the cervix. ( 7572111 )	Abulafia O...Sherer DM	1995
37	Small cell carcinoma of the cervix treated with concurrent radiotherapy, cisplatin, and etoposide. ( 7896189 )	Hoskins PJ...Le Riche J	1995
38	Small cell carcinoma of the cervix. ( 11578477 )	Perrin L...Ward B	1995
39	Small cell carcinoma of the cervix. A clinicopathologic study of 26 patients. ( 8299089 )	Abeler VM...Kj?rstad KE	1994
40	Overexpression of p53 protein and c-erbB-2 protein in small cell carcinoma of the cervix uteri. ( 8103676 )	Holm R....Nesland J.M.	1993
41	Treatment of small cell carcinoma of the cervix with cisplatin, doxorubicin, and etoposide. ( 1330847 )	Morris M...Wharton JT	1992
42	Small cell carcinoma of the cervix: a clinical and flow-cytometric study. ( 1655594 )	Miller B...Photopulos G	1991
43	Adjuvant therapy for neuroendocrine small cell carcinoma of the cervix: review of the literature. ( 1660433 )	O'Hanlan KA...Rodriguez-Rodriguez L	1991
44	Treatment of small-cell carcinoma of the cervix with weekly combination chemotherapy. ( 1697475 )	Tabbara IA...Stewart FM	1990
45	Small cell carcinoma of the cervix with inappropriate antidiuretic hormone secretion. Case report. ( 2167728 )	Kothe MJ...Schellekens PT	1990
46	Simultaneous small cell carcinoma of the cervix and adenocarcinoma of the ovary. ( 2172123 )	Miller B...Photopulus G	1990
47	Eaton-Lambert syndrome as a harbinger of recurrent small-cell carcinoma of the cervix with improvement after combination chemotherapy. ( 2841632 )		1988
48	The pathologic spectrum of small cell carcinoma of the cervix. ( 2852175 )	Groben P...Askin F	1985

Sources

Genes for Cervix Small Cell Carcinoma

Genes related to Cervix Small Cell Carcinoma (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ENO2	Enolase 2	Protein Coding	15.58	DISEASES inferred ¹⁵
2	MAPK8IP1	Mitogen-Activated Protein Kinase 8 Interacting Protein 1	Protein Coding	15.26	DISEASES inferred ¹⁵
3	SYP	Synaptophysin	Protein Coding	15.14	DISEASES inferred ¹⁵
4	CHGA	Chromogranin A	Protein Coding	14.55	DISEASES inferred ¹⁵
5	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	14.06	DISEASES inferred ¹⁵
6	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	13.84	DISEASES inferred ¹⁵
7	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	13.74	DISEASES inferred ¹⁵
8	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	13.65	DISEASES inferred ¹⁵
9	POMC	Proopiomelanocortin	Protein Coding	13.59	DISEASES inferred ¹⁵
10	TP53	Tumor Protein P53	Protein Coding	13.24	DISEASES inferred ¹⁵
11	CDH2	Cadherin 2	Protein Coding	13.05	DISEASES inferred ¹⁵
12	AVP	Arginine Vasopressin	Protein Coding	13.05	DISEASES inferred ¹⁵
13	MAPK8IP2	Mitogen-Activated Protein Kinase 8 Interacting Protein 2	Protein Coding	5.42	DISEASES inferred ¹⁵
14	CNN1	Calponin 1	Protein Coding	4.92	DISEASES inferred ¹⁵
15	TAGLN	Transgelin	Protein Coding	4.47	DISEASES inferred ¹⁵
16	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	3.35	DISEASES inferred ¹⁵
17	CDH17	Cadherin 17	Protein Coding	3.34	DISEASES inferred ¹⁵

Sources

Variations for Cervix Small Cell Carcinoma

Cosmic variations for Cervix Small Cell Carcinoma:

⁹

#	Cosmic Mut ID	Gene Symbol	COSMIC Disease Classification (Primary site, Site subtype, Primary histology, Histology subtype)	Mutation CDS	Mutation AA	GRCh38 Location	Conf
1	COSM6932	TP53	cervix,NS,carcinoma,small cell carcinoma	c.733G>A	p.G245S	17:7674230-7674230	12
2	COSM145923	SF3B1	cervix,NS,carcinoma,small cell carcinoma	c.2225G>A	p.G742D	2:197401887-197401887	12
3	COSM6943414	RPS6KB2	cervix,NS,carcinoma,small cell carcinoma	c.356A>C	p.E119A	11:67431414-67431414	12
4	COSM6943412	RAD54L	cervix,NS,carcinoma,small cell carcinoma	c.388G>T	p.D130Y	1:46260080-46260080	12
5	COSM763	PIK3CA	cervix,NS,carcinoma,small cell carcinoma	c.1633G>A	p.E545K	3:179218303-179218303	12
6	COSM760	PIK3CA	cervix,NS,carcinoma,small cell carcinoma	c.1624G>A	p.E542K	3:179218294-179218294	12
7	COSM3832368	KMT2C	cervix,NS,carcinoma,small cell carcinoma	c.4174C>T	p.Q1392*	7:152199378-152199378	12
8	COSM125370		cervix,NS,carcinoma,small cell carcinoma	c.1633G>A	p.E545K	3:179218303-179218303	12
9	COSM6943413		cervix,NS,carcinoma,small cell carcinoma	c.356A>C	p.E119A	11:67431414-67431414	12
10	COSM3832367		cervix,NS,carcinoma,small cell carcinoma	c.4174C>T	p.Q1392*	7:152199378-152199378	12

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Expression for Cervix Small Cell Carcinoma

Search GEO for disease gene expression data for Cervix Small Cell Carcinoma.

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Pathways for Cervix Small Cell Carcinoma

Pathways related to Cervix Small Cell Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	ERK Signaling ⁶⁴ Show member pathways ILK Signaling ⁶⁴ MAPK Signaling ⁶⁴ Molecular Mechanisms of Cancer ⁶⁴ Rho Family GTPases ⁶⁴	13.08	CDH17 CDH2 CDKN2A CXCL1 CXCR1 CXCR2
2	Adhesion ⁴	11.59	CDH17 CDH2 NCAM1
3	Neuroscience ⁴	11.56	AVP ENO2 NCAM1 POMC SYP
4	Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions ⁶⁵ Show member pathways Chemokine receptors bind chemokines ⁶⁶	11.5	CXCL1 CXCR1 CXCR2
5	Senescence and Autophagy in Cancer ¹	11.36	CDKN2A CXCL1 TP53

Sources

GO Terms for Cervix Small Cell Carcinoma

Cellular components related to Cervix Small Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	secretory granule	GO:0030141	8.8	AVP CHGA POMC

Biological processes related to Cervix Small Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of JNK cascade	GO:0046328	9.37	MAPK8IP1 MAPK8IP2
2	neutrophil chemotaxis	GO:0030593	9.33	CXCL1 CXCR1 CXCR2
3	dendritic cell chemotaxis	GO:0002407	9.32	CXCR1 CXCR2
4	replicative senescence	GO:0090399	9.26	CDKN2A TP53
5	chemokine-mediated signaling pathway	GO:0070098	9.13	CXCL1 CXCR1 CXCR2
6	interleukin-8-mediated signaling pathway	GO:0038112	8.62	CXCR1 CXCR2

Molecular functions related to Cervix Small Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein kinase binding	GO:0019901	9.55	CDH2 CDKN2A MAPK8IP1 MAPK8IP2 TP53
2	C-X-C chemokine receptor activity	GO:0016494	9.32	CXCR1 CXCR2
3	MAP-kinase scaffold activity	GO:0005078	9.26	MAPK8IP1 MAPK8IP2
4	interleukin-8 binding	GO:0019959	8.96	CXCR1 CXCR2
5	interleukin-8 receptor activity	GO:0004918	8.62	CXCR1 CXCR2

Sources

Sources for Cervix Small Cell Carcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

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⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

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¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia