CBS
MCID: CHR158
MIFTS: 23

Charles Bonnet Syndrome (CBS)

Categories: Eye diseases, Mental diseases, Rare diseases

Aliases & Classifications for Charles Bonnet Syndrome

MalaCards integrated aliases for Charles Bonnet Syndrome:

Name: Charles Bonnet Syndrome 20 70
Cbs 20

Classifications:



External Ids:

UMLS 70 C0339731

Summaries for Charles Bonnet Syndrome

GARD : 20 Charles Bonnet syndrome (CBS) is a disease in which visual hallucinations occur as a result of vision loss. CBS is not thought to be related to psychosis or dementia and people with CBS are aware that their hallucinations are not real. The hallucinations people with CBS experience can be described as simple or complex. Simple hallucinations include shapes and patterns, while complex include images of people, vehicles, animals, and plants. Hallucination episodes can range from a few seconds to hours and may recur over the course of several days to years. The cause of CBS is not well understood, but it is thought to be related to the brain continuing to interpret images, even in their absence. There are many underlying diseases of vision loss that are associated with CBS, such as macular degeneration and stroke. Hallucinations may resolve in instances where the the underlying vision issue can be corrected (such as with cataracts ). Treatment differs depending on the impact symptoms have on a person's life. Some people are taught to block their hallucinations, while others may benefit from antipsychotic medications.

MalaCards based summary : Charles Bonnet Syndrome, also known as cbs, is related to homocystinuria due to cystathionine beta-synthase deficiency and homocystinuria. An important gene associated with Charles Bonnet Syndrome is HARS1 (Histidyl-TRNA Synthetase 1). Affiliated tissues include eye, occipital lobe and cortex.

Wikipedia : 73 Visual release hallucinations, also known as Charles Bonnet syndrome or CBS, are a type of... more...

Related Diseases for Charles Bonnet Syndrome

Diseases related to Charles Bonnet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 245)
# Related Disease Score Top Affiliating Genes
1 homocystinuria due to cystathionine beta-synthase deficiency 11.8
2 homocystinuria 11.6
3 homocysteinemia 11.3
4 usher syndrome, type iiib 11.3
5 homocystinuria caused by cystathionine beta-synthase deficiency 11.1
6 neural tube defects 11.1
7 down syndrome 11.0
8 thrombophilia due to thrombin defect 11.0
9 marfan syndrome 11.0
10 hypermethioninemia 11.0
11 familial hypercholesterolemia 11.0
12 progressive supranuclear palsy-corticobasal syndrome 10.9
13 isolated ectopia lentis 10.9
14 macular degeneration, age-related, 1 10.9
15 wolff-parkinson-white syndrome 10.9
16 lens subluxation 10.9
17 pyridoxine deficiency anemia 10.9
18 methionine adenosyltransferase i/iii deficiency 10.8
19 methylmalonic aciduria and homocystinuria, cblc type 10.8
20 glycine n-methyltransferase deficiency 10.8
21 malignant hyperthermia 10.8
22 acute megakaryocytic leukemia 10.8
23 subacute delirium 10.6
24 intraocular pressure quantitative trait locus 10.5
25 yemenite deaf-blind hypopigmentation syndrome 10.4
26 dementia 10.4
27 microvascular complications of diabetes 5 10.4
28 neuroretinitis 10.4
29 epilepsy 10.4
30 retinitis 10.4
31 eye disease 10.4
32 corticobasal degeneration 10.3
33 retinitis pigmentosa 10.3
34 kuhnt-junius degeneration 10.3
35 optic nerve disease 10.3
36 cataract 10.3
37 dementia, lewy body 10.3
38 3-methylglutaconic aciduria, type iii 10.3
39 meningioma, familial 10.3
40 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.3
41 intracranial meningioma 10.3
42 optic neuritis 10.3
43 neuritis 10.3
44 secretory meningioma 10.3
45 lymphoplasmacyte-rich meningioma 10.3
46 hereditary optic neuropathy 10.3
47 temporal arteritis 10.2
48 mild cognitive impairment 10.2
49 sensorineural hearing loss 10.2
50 pituitary adenoma 10.2

Graphical network of the top 20 diseases related to Charles Bonnet Syndrome:



Diseases related to Charles Bonnet Syndrome

Symptoms & Phenotypes for Charles Bonnet Syndrome

Drugs & Therapeutics for Charles Bonnet Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Control Trial of Patients With a Charles Bonnet Syndrome Completed NCT03148249
2 The Neurochemistry and Connectivity in the Brain in Charles Bonnet Syndrome Not yet recruiting NCT04777630

Search NIH Clinical Center for Charles Bonnet Syndrome

Genetic Tests for Charles Bonnet Syndrome

Anatomical Context for Charles Bonnet Syndrome

MalaCards organs/tissues related to Charles Bonnet Syndrome:

40
Eye, Occipital Lobe, Cortex, Thalamus, Pituitary, Temporal Lobe

Publications for Charles Bonnet Syndrome

Articles related to Charles Bonnet Syndrome:

(show top 50) (show all 409)
# Title Authors PMID Year
1
Prevalence of Charles Bonnet syndrome in patients with glaucoma: a systematic review with meta-analyses. 61
32749787 2021
2
Cerebellar correlates of visual hallucinations in Parkinson's disease and Charles Bonnet Syndrome. 61
33390262 2021
3
Vision loss and hallucinations: perspectives from neurology and ophthalmology. 61
33230034 2021
4
How do the blind 'see'? The role of spontaneous brain activity in self-generated perception. 61
33367630 2021
5
Power spectral density and coherence analysis of eye disease with and without visual hallucination. 61
33127444 2021
6
Exacerbation of visual hallucinations in Charles Bonnet syndrome due to the social implications of COVID-19. 61
33628948 2021
7
Charles Bonnet Syndrome as Another Cause of Visual Hallucinations. 61
33654605 2021
8
Benefit of psychiatric evaluation on anxiety in patients with Charles Bonnet syndrome. 61
33693058 2021
9
Concurrent Delusions of Ocular Parasitosis and Complex Visual Hallucinations from Charles Bonnet Syndrome Treated Successfully with Aripiprazole in an Elderly Male: A Case Report. 61
33635770 2020
10
Case Report: Effect of a Retinal Prosthesis System on Charles Bonnet Visual Hallucinations. 61
33259381 2020
11
Visual hallucinations in psychiatric, neurologic, and ophthalmologic disease. 61
33009079 2020
12
Visual hallucinations in psychiatric, neurologic, and ophthalmologic disease. 61
32897918 2020
13
Vivid Visual Hallucinations in Visually Impaired: Charles Bonnet Syndrome - An Analog to "Phantom-Limb Phenomenon". 61
33623292 2020
14
Three cases of Charles Bonnet Syndrome in patients with advanced glaucomatous visual field loss but preserved visual acuity. 61
32918400 2020
15
Atypical Charles Bonnet Syndrome in a patient with hemianopia and cognitive impairment after right occipitotemporal stroke. 61
32250519 2020
16
Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome. 61
32933935 2020
17
Reversible Charles Bonnet syndrome secondary to upper lid ptosis. 61
31379235 2020
18
An elderly patient with Charles Bonnet Syndrome misdiagnosed as Lewy Body Dementia. 61
32447723 2020
19
A rare case report of Lilliputian and Brobdingnagian hallucinations in a case of pemphigus vulgaris. 61
33165350 2020
20
Cerebellar Parieto-occipital Posterior Reversible Encephalopathy Syndrome and Cerebral Metamorphopsia Associated with Asymptomatic Atrial Septum Vegetation and Renal Disease: Case Report. 61
32516303 2020
21
Prevalence of Charles Bonnet syndrome in patients with age-related macular degeneration: systematic review and meta-analysis. 61
31654492 2020
22
Clinical Characteristics of the Charles Bonnet Syndrome in Patients with Neovascular Age-Related Macular Degeneration: The Importance of Early Detection. 61
31986513 2020
23
[Visual hallucinations in the works of Oliver Sacks]. 61
31930472 2020
24
Charles Bonnet Syndrome in a Patient with Parkinson's Disease and Bilateral Posterior Capsule Opacification. 61
32021492 2020
25
Evaluation of the Clinical Features, Management, and Prognoses of Patients With Charles Bonnet Syndrome. 61
31703034 2019
26
Charles Bonnet Syndrome Treated With Pimavanserin. 61
31022063 2019
27
Functional MRI study in a case of Charles Bonnet syndrome related to LHON. 61
31888524 2019
28
The therapeutic role of repetitive transcranial magnetic stimulation (rTMS) in parkinsonian visual hallucinations: Electrophysiological correlates. 61
31477464 2019
29
The elephant in the room: understanding the pathogenesis of Charles Bonnet syndrome. 61
31591762 2019
30
Glycerol Used for Controlling the Increased Intracranial Pressure-Related Charles Bonnet Syndrome. 61
30839324 2019
31
Correction to: The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria. 61
31583476 2019
32
Charles Bonnet syndrome in a young patient with a history of epilepsy. 61
28081973 2019
33
Auditory Charles Bonnet syndrome: case report. 61
31249098 2019
34
"Playthings of the Brain": Phantom Visions in Charles Bonnet Syndrome. 61
31219409 2019
35
Screening for Charles Bonnet syndrome: Should the definition be reconsidered? 61
31238427 2019
36
The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria. 61
31342218 2019
37
Alice in Wonderland Syndrome and Charles Bonnet Syndrome: Similar but not so similar! 61
30977394 2019
38
Charles Bonnet syndrome: development and validation of a screening and multidimensional descriptive questionnaire. 61
31109471 2019
39
[Giant Cell Arteritis and Charles Bonnet Syndrome. The Case of Saint Martin of Leon]. 61
31315406 2019
40
The sound of music: A rare case of auditory Charles Bonnet syndrome in an elderly male. 61
31046031 2019
41
Charles Bonnet syndrome and periodic alternating nystagmus: Moving visual hallucinations. 61
30700594 2019
42
Charles Bonnet syndrome in Leber's hereditary optic neuropathy. 61
30687896 2019
43
FDG-PET Scanning Shows Distributed Changes in Cortical Activity Associated with Visual Hallucinations in Eye Disease. 61
30160221 2019
44
The Last Witness to Creation: A Case of Charles Bonnet Syndrome. 61
31012826 2019
45
Charles Bonnet Syndrome: so much more than just a side effect of sight loss. 61
31701085 2019
46
Repetitive TranscranialMagnetic Stimulation-Induced Charles Bonnet Syndrome. 61
29980301 2019
47
Think sight loss, think Charles Bonnet syndrome. 61
31903448 2019
48
Resting-state functional connectivity and cortical thickness characterization of a patient with Charles Bonnet syndrome. 61
31318888 2019
49
[Complex visual hallucinations in the visually impaired, the Charles Bonnet syndrome]. 61
30667516 2019
50
Charles Bonnet syndrome. 61
30194097 2018

Variations for Charles Bonnet Syndrome

Expression for Charles Bonnet Syndrome

Search GEO for disease gene expression data for Charles Bonnet Syndrome.

Pathways for Charles Bonnet Syndrome

GO Terms for Charles Bonnet Syndrome

Sources for Charles Bonnet Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
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44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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