CBS
MCID: CHR158
MIFTS: 26

Charles Bonnet Syndrome (CBS)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Charles Bonnet Syndrome

MalaCards integrated aliases for Charles Bonnet Syndrome:

Name: Charles Bonnet Syndrome 53 73
Cbs 53

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 73 C0339731

Summaries for Charles Bonnet Syndrome

NIH Rare Diseases : 53 Charles Bonnet syndrome (CBS) is a disease in which visual hallucinations occur as a result of vision loss. CBS is not thought to be related to psychosis or dementia and people with CBS are aware that their hallucinations are not real. The hallucinations people with CBS experience can be described as simple or complex. Simple hallucinations include shapes and patterns, while complex include images of people, vehicles, animals, and plants. Hallucination episodes can range from a few seconds to hours and may recur over the course of several days to years.  The cause of CBS is not well understood, but it is thought to be related to the brain continuing to interpret images, even in their absence. There are many underlying diseases of vision loss that are associated with CBS, such as macular degeneration and stroke. Hallucinations may resolve in instances where the the underlying vision issue can be corrected (such as with cataracts). Treatment differs depending on the impact symptoms have on a person's life. Some people are taught to block their hallucinations, while others may benefit from antipsychotic medications.

MalaCards based summary : Charles Bonnet Syndrome, also known as cbs, is related to homocystinuria due to cbs deficiency and homocystinuria. An important gene associated with Charles Bonnet Syndrome is HARS (Histidyl-TRNA Synthetase). Affiliated tissues include eye, brain and pituitary.

Wikipedia : 76 Visual release hallucinations, also known as Charles Bonnet syndrome (CBS) is a type of psychophysical... more...

Related Diseases for Charles Bonnet Syndrome

Diseases related to Charles Bonnet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 148)
# Related Disease Score Top Affiliating Genes
1 homocystinuria due to cbs deficiency 12.7
2 homocystinuria 12.3
3 homocystinuria due to cystathionine beta-synthase deficiency 12.3
4 homocysteinemia 11.9
5 heart disease 11.5
6 myocardial infarction 11.4
7 phaeohyphomycosis 11.3
8 usher syndrome, type iiib 11.3
9 neural tube defects 11.2
10 megakaryocytic leukemia 11.1
11 hypermethioninemia 11.1
12 myelomeningocele 11.1
13 vascular disease 11.1
14 cerebrovascular disease 11.1
15 marfan syndrome 11.1
16 down syndrome 11.1
17 wolff-parkinson-white syndrome 11.1
18 glycine n-methyltransferase deficiency 11.1
19 speech and communication disorders 11.1
20 lens subluxation 11.1
21 progressive supranuclear palsy-corticobasal syndrome 11.1
22 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 11.0
23 cystathioninuria 11.0
24 urofacial syndrome 1 11.0
25 methionine adenosyltransferase i/iii deficiency 11.0
26 methylmalonic aciduria and homocystinuria, cblc type 11.0
27 supranuclear palsy, progressive, 1 11.0
28 grange syndrome 11.0
29 bartter syndrome, type 3 11.0
30 superficial mycosis 11.0
31 otomycosis 11.0
32 trichosporonosis 11.0
33 focal hand dystonia 11.0
34 paraphilia disorder 11.0
35 agraphia 11.0
36 isolated ectopia lentis 11.0
37 exhibitionism 11.0
38 voyeurism 11.0
39 tinea cruris 11.0
40 transvestism 11.0
41 fetishism 11.0
42 cicatricial ectropion 11.0
43 tinea unguium 11.0
44 tinea manuum 11.0
45 echolalia 11.0
46 gait apraxia 11.0
47 ideomotor apraxia 11.0
48 gerstmann syndrome 11.0
49 asymmetric motor neuropathy 11.0
50 amino acid metabolic disorder 11.0

Graphical network of the top 20 diseases related to Charles Bonnet Syndrome:



Diseases related to Charles Bonnet Syndrome

Symptoms & Phenotypes for Charles Bonnet Syndrome

Drugs & Therapeutics for Charles Bonnet Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Trial of Patients With a Charles Bonnet Syndrome Completed NCT03148249 Not Applicable

Search NIH Clinical Center for Charles Bonnet Syndrome

Genetic Tests for Charles Bonnet Syndrome

Anatomical Context for Charles Bonnet Syndrome

MalaCards organs/tissues related to Charles Bonnet Syndrome:

41
Eye, Brain, Pituitary, Lung, Heart, Breast, Occipital Lobe

Publications for Charles Bonnet Syndrome

Articles related to Charles Bonnet Syndrome:

(show top 50) (show all 593)
# Title Authors Year
1
Family physician awareness of Charles Bonnet syndrome. ( 29471318 )
2018
2
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. ( 29778582 )
2018
3
Hallucinatory experiences in visually impaired individuals: Charles Bonnet syndrome - implications for research and clinical practice. ( 29930220 )
2018
4
Charles Bonnet syndrome secondary to multifocal intraocular lens implantation. ( 29891160 )
2018
5
A low dose of risperidone resolved Charles Bonnet syndrome after an unsuccessful trial of quetiapine: a case report. ( 29593414 )
2018
6
Complex visual hallucinatory experience in an elderly blind woman with glaucoma: revisiting Charles Bonnet syndrome. ( 29744073 )
2018
7
Charles Bonnet Syndrome in a Geriatric Female Patient: A Case Report. ( 29570961 )
2018
8
Charles Bonnet Syndrome and Other Hallucinatory Phenomena. ( 29145190 )
2018
9
Repetitive Transcranial Magnetic Stimulation-Induced Charles Bonnet Syndrome. ( 29980301 )
2018
10
Charles Bonnet syndrome versus Occipital Epilepsy, a diagnostic challenge. ( 29957762 )
2018
11
Remission of Charles Bonnet syndrome after cataract extraction. ( 30502996 )
2018
12
Gulliver's world: Persistent lilliputian hallucinations as manifestation of Charles Bonnet syndrome in a case of cataract and normal pressure hydrocephalus. ( 30405266 )
2018
13
Challenges of diagnosing and treating Charles Bonnet syndrome. ( 30140592 )
2018
14
Charles Bonnet syndrome. ( 30194097 )
2018
15
Charles Bonnet syndrome - disturbing 'playthings of the brain'. ( 30224367 )
2018
16
Charles Bonnet Syndrome: Cortical Hyperexcitability and Visual Hallucination. ( 30399348 )
2018
17
Ave Maria and Visions of Children: Atypical Charles Bonnet Syndrome or Two Coexisting Deafferentation Phenomena? ( 30402359 )
2018
18
CBS mutations are good predictors for B6-responsiveness: A study based on the analysis of 35 Brazilian Classical Homocystinuria patients. ( 30264510 )
2018
19
miR-191 secreted by platelet-derived microvesicles induced apoptosis of renal tubular epithelial cells and participated in renal ischemia-reperfusion injury via inhibiting CBS. ( 30394829 )
2018
20
Data on whole genome sequencing of the oomycete Pythium insidiosum strain CBS 101555 from a horse with pythiosis in Brazil. ( 30537981 )
2018
21
CBS mutations and MTFHR SNPs causative of hyperhomocysteinemia in Pakistani children. ( 29600437 )
2018
22
Impaired CBS-H2S signaling axis contributes to MPTP-induced neurodegeneration in a mouse model of Parkinson's disease. ( 28774789 )
2018
23
Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates. ( 28900755 )
2018
24
Enzymatic Hydrolysis of Black Liquor Xylan by a Novel Xylose-Tolerant, Thermostable β-Xylosidase from a Tropical Strain of Aureobasidium pullulans CBS 135684. ( 28918541 )
2018
25
Erratum to: Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates. ( 29027144 )
2018
26
Mating-type switching in CBS 732T derived subcultures unveils potential genetic and phenotypic novelties in haploid Zygosaccharomyces rouxii. ( 29228275 )
2018
27
Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS). ( 29254576 )
2018
28
Draft Genome Sequence of Saccharomycopsis fermentans CBS 7830, a Predacious Yeast Belonging to the Saccharomycetales. ( 29326220 )
2018
29
Draft Genome Sequence of the Sordariomycete Lecythophora (Coniochaeta) hoffmannii CBS 245.38. ( 29449401 )
2018
30
Enhancing the catalytic activity of a novel GH5 cellulase GtCel5 from Gloeophyllum trabeum CBS 900.73 by site-directed mutagenesis on loop 6. ( 29588661 )
2018
31
Toward High-Level Theoretical Studies of Large Biodiesel Molecules: An ONIOM [QCISD(T)/CBS:DFT] Study of the Reactions between Unsaturated Methyl Esters (C nH2 n-1COOCH3) and Hydrogen Radical. ( 29745664 )
2018
32
Optimized yeast-based in vitro bioassay for determination of estrogenic and androgenic activity of hydroxylated / methoxylated metabolites of BDEs / CBs and related lipophilic organic pollutants. ( 29775424 )
2018
33
MiR-125b-5p is involved in oxygen and glucose deprivation injury in PC-12 cells via CBS/H2S pathway. ( 29777774 )
2018
34
Pd NP-Loaded and Covalently Cross-Linked COF Membrane Microreactor for Aqueous CBs Dechlorination at Room Temperature. ( 29847916 )
2018
35
Gene expression microarray data from mouse CBS treated with rTMS for 30 days, mouse cerebrum and CBS treated with rTMS for 40 days. ( 29876464 )
2018
36
Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria. ( 29915055 )
2018
37
S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice. ( 30023284 )
2018
38
Mouse modeling and structural analysis of the p.G307S mutation in human cystathionine β-synthase (CBS) reveal effects on CBS activity but not stability. ( 30030379 )
2018
39
Debaryomyces hansenii CBS 8339 β-glucan enhances immune responses and down-stream gene signaling pathways in goat peripheral blood leukocytes. ( 30031015 )
2018
40
Morphological differences between aerial and submerged sporidia of bio-fongicide Pseudozyma flocculosa CBS 16788. ( 30067835 )
2018
41
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse. ( 30088182 )
2018
42
CBS extrapolation in electronic structure pushed to the end: a revival of minimal and sub-minimal basis sets. ( 30113053 )
2018
43
Structural, Physiological and Regulatory Analysis of Maltose Transporter Genes in Saccharomyces eubayanus CBS 12357T. ( 30147677 )
2018
44
Severity dependent distribution of impairments in PSP and CBS: Interactive visualizations. ( 30201421 )
2018
45
Production of Arachidonic Acid and Eicosapentaenoic Acid by Mortierella alpina CBS 528.72 on Date Waste. ( 30228794 )
2018
46
E2β Stimulates Ovine Uterine Artery Endothelial Cell H2S Production in vitro by ER-dependent Upregulation of CBS and CTH Expression. ( 30277497 )
2018
47
Quantitative proteomic analysis of xylose fermentation strain Pichia stipitis CBS 5776 to lignocellulosic inhibitors acetic acid, vanillin and 5-hydroxymethylfurfural. ( 30299476 )
2018
48
Estradiol-17β stimulates H2 S biosynthesis by ER-dependent CBS and CSE transcription in uterine artery smooth muscle cells in vitro. ( 30317617 )
2018
49
Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism. ( 30323246 )
2018
50
Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster. ( 30408770 )
2018

Variations for Charles Bonnet Syndrome

Expression for Charles Bonnet Syndrome

Search GEO for disease gene expression data for Charles Bonnet Syndrome.

Pathways for Charles Bonnet Syndrome

GO Terms for Charles Bonnet Syndrome

Sources for Charles Bonnet Syndrome

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