MCID: CHR158
MIFTS: 26

Charles Bonnet Syndrome

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Charles Bonnet Syndrome

MalaCards integrated aliases for Charles Bonnet Syndrome:

Name: Charles Bonnet Syndrome 54 74
Cbs 54

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 74 C0339731

Summaries for Charles Bonnet Syndrome

NIH Rare Diseases : 54 Charles Bonnet syndrome (CBS) is a disease in which visual hallucinations occur as a result of vision loss. CBS is not thought to be related to psychosis or dementia and people with CBS are aware that their hallucinations are not real. The hallucinations people with CBS experience can be described as simple or complex. Simple hallucinations include shapes and patterns, while complex include images of people, vehicles, animals, and plants. Hallucination episodes can range from a few seconds to hours and may recur over the course of several days to years.  The cause of CBS is not well understood, but it is thought to be related to the brain continuing to interpret images, even in their absence. There are many underlying diseases of vision loss that are associated with CBS, such as macular degeneration and stroke. Hallucinations may resolve in instances where the the underlying vision issue can be corrected (such as with cataracts). Treatment differs depending on the impact symptoms have on a person's life. Some people are taught to block their hallucinations, while others may benefit from antipsychotic medications.

MalaCards based summary : Charles Bonnet Syndrome, also known as cbs, is related to homocystinuria due to cbs deficiency and homocystinuria due to cystathionine beta-synthase deficiency. An important gene associated with Charles Bonnet Syndrome is HARS (Histidyl-TRNA Synthetase). Affiliated tissues include brain, eye and prostate.

Wikipedia : 77 Visual release hallucinations, known as Charles Bonnet Syndrome, are a type of psychophysical visual... more...

Related Diseases for Charles Bonnet Syndrome

Diseases related to Charles Bonnet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 homocystinuria due to cbs deficiency 12.8
2 homocystinuria due to cystathionine beta-synthase deficiency 12.5
3 homocystinuria 12.4
4 homocysteinemia 12.0
5 usher syndrome, type iiib 11.4
6 marfan syndrome 11.2
7 neural tube defects 11.2
8 megakaryocytic leukemia 11.2
9 hypermethioninemia 11.2
10 wolff-parkinson-white syndrome 11.1
11 methionine adenosyltransferase i/iii deficiency 11.1
12 methylmalonic aciduria and homocystinuria, cblc type 11.1
13 grange syndrome 11.1
14 glycine n-methyltransferase deficiency 11.1
15 isolated ectopia lentis 11.1
16 lens subluxation 11.1
17 vascular disease 11.1
18 pyridoxine deficiency anemia 11.1
19 homocystinuria caused by cystathionine beta-synthase deficiency 11.1
20 progressive supranuclear palsy-corticobasal syndrome 11.1
21 macular degeneration, age-related, 1 10.7
22 dementia 10.5
23 epilepsy 10.5
24 multiple sclerosis 10.3
25 kuhnt-junius degeneration 10.3
26 retinitis 10.3
27 temporal arteritis 10.2
28 retinitis pigmentosa 10.2
29 leber congenital amaurosis 4 10.2
30 cataract 10.2
31 pituitary adenoma 10.2
32 adenoma 10.2
33 pancreatic ductal adenocarcinoma 10.2
34 dementia, lewy body 10.1
35 migraine with or without aura 1 10.1
36 thrombophilia due to thrombin defect 10.1
37 glaucoma 3, primary congenital, a 10.1
38 hydrocephalus, normal-pressure 10.1
39 scapuloperoneal myopathy, x-linked dominant 10.1
40 synesthesia 10.1
41 brain injury 10.1
42 diabetes mellitus 10.1
43 hydrocephalus 10.1
44 vitamin b12 deficiency 10.1
45 thrombosis 10.1
46 cytomegalovirus retinitis 10.1
47 neurosarcoidosis 10.1
48 optic nerve disease 10.1
49 post-traumatic stress disorder 10.1
50 ischemia 10.1

Graphical network of the top 20 diseases related to Charles Bonnet Syndrome:



Diseases related to Charles Bonnet Syndrome

Symptoms & Phenotypes for Charles Bonnet Syndrome

Drugs & Therapeutics for Charles Bonnet Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Trial of Patients With a Charles Bonnet Syndrome Completed NCT03148249 Not Applicable

Search NIH Clinical Center for Charles Bonnet Syndrome

Genetic Tests for Charles Bonnet Syndrome

Anatomical Context for Charles Bonnet Syndrome

MalaCards organs/tissues related to Charles Bonnet Syndrome:

42
Brain, Eye, Prostate, Occipital Lobe, Colon, Testes, Cortex

Publications for Charles Bonnet Syndrome

Articles related to Charles Bonnet Syndrome:

(show top 50) (show all 709)
# Title Authors Year
1
Repetitive TranscranialMagnetic Stimulation-Induced Charles Bonnet Syndrome. ( 29980301 )
2019
2
Charles Bonnet syndrome in Leber's hereditary optic neuropathy. ( 30687896 )
2019
3
Charles Bonnet syndrome and periodic alternating nystagmus: Moving visual hallucinations. ( 30700594 )
2019
4
Glycerol Used for Controlling the Increased Intracranial Pressure-Related Charles Bonnet Syndrome. ( 30839324 )
2019
5
Alice in Wonderland Syndrome and Charles Bonnet Syndrome: Similar but not so similar! ( 30977394 )
2019
6
The Last Witness to Creation: A Case of Charles Bonnet Syndrome. ( 31012826 )
2019
7
Charles Bonnet Syndrome Treated With Pimavanserin. ( 31022063 )
2019
8
The sound of music: A rare case of auditory Charles Bonnet syndrome in an elderly male. ( 31046031 )
2019
9
Charles Bonnet syndrome: development and validation of a screening and multidimensional descriptive questionnaire. ( 31109471 )
2019
10
Complete Genome Sequence of Malassezia restricta CBS 7877, an Opportunist Pathogen Involved in Dandruff and Seborrheic Dermatitis. ( 30746521 )
2019
11
Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a. ( 30649339 )
2019
12
miR-191 secreted by platelet-derived microvesicles induced apoptosis of renal tubular epithelial cells and participated in renal ischemia-reperfusion injury via inhibiting CBS. ( 30394829 )
2019
13
Cerebral venous sinus thrombosis due to hyperhomocysteinemia with cystathionine-β-synthase (CBS) gene mutation: A case report. ( 30732165 )
2019
14
CBS promoter hypermethylation increases the risk of hypertension and stroke. ( 30916171 )
2019
15
Accumulation of Tau Protein, Metabolism and Perfusion-Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS). ( 30837933 )
2019
16
Hyperhomocysteinemia induced endothelial progenitor cells dysfunction through hyper-methylation of CBS promoter. ( 30683311 )
2019
17
High incidence of MTHFR, CBS, and MTRR polymorphisms in vitiligo patients. Preliminary report in a retrospective study. ( 30720153 )
2019
18
Evaluation of genotyping methods and costs for MTHFR, CBS and MTRR polymorphisms in patients with vitiligo. ( 30915724 )
2019
19
Estradiol-17β stimulates H2 S biosynthesis by ER-dependent CBS and CSE transcription in uterine artery smooth muscle cells in vitro. ( 30317617 )
2019
20
Simultaneous biodegradation of mixture of carbamates by newly isolated Ascochyta sp. CBS 237.37. ( 30476821 )
2019
21
Probiotic effects of marine Debaryomyces hansenii CBS 8339 on innate immune and antioxidant parameters in newborn goats. ( 30656393 )
2019
22
Complete Genome Sequence of Caldicellulosiruptor changbaiensis CBS-Z, an Extremely Thermophilic, Cellulolytic Bacterium Isolated from a Hot Spring in China. ( 30834376 )
2019
23
CBS extrapolation of Hartree-Fock energy: Pople and Dunning basis sets hand-to-hand on the endeavour. ( 30932108 )
2019
24
Inactivation of the uptake hydrogenase in the purple non-sulfur photosynthetic bacterium Rubrivivax gelatinosus CBS enables a biological water-gas shift platform for H2 production. ( 30968274 )
2019
25
Genome Sequence of an Arthroconidial Yeast, Saprochaete fungicola CBS 625.85. ( 30975801 )
2019
26
Optimal basis sets for CBS extrapolation of the correlation energy: oVxZ and oV(x+d)Z. ( 31005101 )
2019
27
Chromosomal genome assembly of the ethanol production strain CBS 11270 indicates a highly dynamic genome structure in the yeast species Brettanomyces bruxellensis. ( 31042716 )
2019
28
Treatment of CBS deficiency in mice using a minicircle-based naked DNA vector. ( 31084364 )
2019
29
Severity dependent distribution of impairments in PSP and CBS: Interactive visualizations. ( 30201421 )
2019
30
Gulliver's world: Persistent lilliputian hallucinations as manifestation of Charles Bonnet syndrome in a case of cataract and normal pressure hydrocephalus. ( 30405266 )
2018
31
Remission of Charles Bonnet syndrome after cataract extraction. ( 30502996 )
2018
32
Charles Bonnet syndrome secondary to hypertensive crisis. ( 27296495 )
2018
33
Reversible Charles Bonnet Syndrome After Oculoplastic Procedures. ( 27984353 )
2018
34
Cognitive impairment and Charles Bonnet syndrome: a prospective study. ( 28117918 )
2018
35
Pseudo-Charles Bonnet Syndrome With a Frontal Tumor: Visual Hallucinations, the Brain, and the Two-Hit Hypothesis. ( 28774226 )
2018
36
Charles Bonnet Syndrome and Other Hallucinatory Phenomena. ( 29145190 )
2018
37
Family physician awareness of Charles Bonnet syndrome. ( 29471318 )
2018
38
Charles Bonnet Syndrome in a Geriatric Female Patient: A Case Report. ( 29570961 )
2018
39
A low dose of risperidone resolved Charles Bonnet syndrome after an unsuccessful trial of quetiapine: a case report. ( 29593414 )
2018
40
Complex visual hallucinatory experience in an elderly blind woman with glaucoma: revisiting Charles Bonnet syndrome. ( 29744073 )
2018
41
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. ( 29778582 )
2018
42
Charles Bonnet syndrome secondary to multifocal intraocular lens implantation. ( 29891160 )
2018
43
Hallucinatory experiences in visually impaired individuals: Charles Bonnet syndrome - implications for research and clinical practice. ( 29930220 )
2018
44
Charles Bonnet syndrome versus Occipital Epilepsy, a diagnostic challenge. ( 29957762 )
2018
45
Challenges of diagnosing and treating Charles Bonnet syndrome. ( 30140592 )
2018
46
Charles Bonnet syndrome. ( 30194097 )
2018
47
Charles Bonnet syndrome - disturbing 'playthings of the brain'. ( 30224367 )
2018
48
Charles Bonnet Syndrome: Cortical Hyperexcitability and Visual Hallucination. ( 30399348 )
2018
49
Ave Maria and Visions of Children: Atypical Charles Bonnet Syndrome or Two Coexisting Deafferentation Phenomena? ( 30402359 )
2018
50
Homocystinuria due to cystathionine beta-synthase (CBS) deficiency in Russia: Molecular and clinical characterization. ( 29326875 )
2018

Variations for Charles Bonnet Syndrome

Expression for Charles Bonnet Syndrome

Search GEO for disease gene expression data for Charles Bonnet Syndrome.

Pathways for Charles Bonnet Syndrome

GO Terms for Charles Bonnet Syndrome

Sources for Charles Bonnet Syndrome

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