CBS
MCID: CHR158
MIFTS: 26

Charles Bonnet Syndrome (CBS)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Charles Bonnet Syndrome

MalaCards integrated aliases for Charles Bonnet Syndrome:

Name: Charles Bonnet Syndrome 54 74
Cbs 54

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 74 C0339731

Summaries for Charles Bonnet Syndrome

NIH Rare Diseases : 54 Charles Bonnet syndrome (CBS) is a disease in which visual hallucinations occur as a result of vision loss. CBS is not thought to be related to psychosis or dementia and people with CBS are aware that their hallucinations are not real. The hallucinations people with CBS experience can be described as simple or complex. Simple hallucinations include shapes and patterns, while complex include images of people, vehicles, animals, and plants. Hallucination episodes can range from a few seconds to hours and may recur over the course of several days to years.  The cause of CBS is not well understood, but it is thought to be related to the brain continuing to interpret images, even in their absence. There are many underlying diseases of vision loss that are associated with CBS, such as macular degeneration and stroke. Hallucinations may resolve in instances where the the underlying vision issue can be corrected (such as with cataracts). Treatment differs depending on the impact symptoms have on a person's life. Some people are taught to block their hallucinations, while others may benefit from antipsychotic medications.

MalaCards based summary : Charles Bonnet Syndrome, also known as cbs, is related to homocystinuria due to cbs deficiency and homocystinuria. An important gene associated with Charles Bonnet Syndrome is HARS (Histidyl-TRNA Synthetase). Affiliated tissues include brain, eye and occipital lobe.

Wikipedia : 77 Visual release hallucinations, known as Charles Bonnet Syndrome, are a type of psychophysical visual... more...

Related Diseases for Charles Bonnet Syndrome

Diseases related to Charles Bonnet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 142)
# Related Disease Score Top Affiliating Genes
1 homocystinuria due to cbs deficiency 12.7
2 homocystinuria 12.4
3 homocystinuria due to cystathionine beta-synthase deficiency 12.3
4 homocysteinemia 12.0
5 usher syndrome, type iiib 11.4
6 marfan syndrome 11.2
7 neural tube defects 11.2
8 megakaryocytic leukemia 11.2
9 hypermethioninemia 11.2
10 wolff-parkinson-white syndrome 11.1
11 methionine adenosyltransferase i/iii deficiency 11.1
12 methylmalonic aciduria and homocystinuria, cblc type 11.1
13 grange syndrome 11.1
14 glycine n-methyltransferase deficiency 11.1
15 isolated ectopia lentis 11.1
16 lens subluxation 11.1
17 vascular disease 11.1
18 homocystinuria caused by cystathionine beta-synthase deficiency 11.1
19 pyridoxine deficiency 11.1
20 progressive supranuclear palsy-corticobasal syndrome 11.1
21 macular degeneration, age-related, 1 10.7
22 neuroblastoma 10.6
23 dementia 10.5
24 epilepsy 10.5
25 multiple sclerosis 10.3
26 kuhnt-junius degeneration 10.3
27 retinitis 10.3
28 temporal arteritis 10.2
29 retinitis pigmentosa 10.2
30 leber congenital amaurosis 4 10.2
31 cataract 10.2
32 pituitary adenoma 10.2
33 adenoma 10.2
34 pancreatic ductal adenocarcinoma 10.2
35 corticobasal degeneration 10.1
36 dementia, lewy body 10.1
37 migraine with or without aura 1 10.1
38 thrombophilia due to thrombin defect 10.1
39 glaucoma 3, primary congenital, a 10.1
40 hydrocephalus, normal-pressure 10.1
41 synesthesia 10.1
42 brain injury 10.1
43 diabetes mellitus 10.1
44 hydrocephalus 10.1
45 vitamin b12 deficiency 10.1
46 thrombosis 10.1
47 cytomegalovirus retinitis 10.1
48 neurosarcoidosis 10.1
49 optic nerve disease 10.1
50 post-traumatic stress disorder 10.1

Graphical network of the top 20 diseases related to Charles Bonnet Syndrome:



Diseases related to Charles Bonnet Syndrome

Symptoms & Phenotypes for Charles Bonnet Syndrome

Drugs & Therapeutics for Charles Bonnet Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Trial of Patients With a Charles Bonnet Syndrome Completed NCT03148249 Not Applicable

Search NIH Clinical Center for Charles Bonnet Syndrome

Genetic Tests for Charles Bonnet Syndrome

Anatomical Context for Charles Bonnet Syndrome

MalaCards organs/tissues related to Charles Bonnet Syndrome:

42
Brain, Eye, Occipital Lobe, Testes, Cortex, Endothelial, Thalamus

Publications for Charles Bonnet Syndrome

Articles related to Charles Bonnet Syndrome:

(show top 50) (show all 602)
# Title Authors Year
1
Charles Bonnet syndrome in Leber's hereditary optic neuropathy. ( 30687896 )
2019
2
Charles Bonnet syndrome and periodic alternating nystagmus: Moving visual hallucinations. ( 30700594 )
2019
3
Glycerol Used for Controlling the Increased Intracranial Pressure-Related Charles Bonnet Syndrome. ( 30839324 )
2019
4
Complete Genome Sequence of Malassezia restricta CBS 7877, an Opportunist Pathogen Involved in Dandruff and Seborrheic Dermatitis. ( 30746521 )
2019
5
Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a. ( 30649339 )
2019
6
miR-191 secreted by platelet-derived microvesicles induced apoptosis of renal tubular epithelial cells and participated in renal ischemia-reperfusion injury via inhibiting CBS. ( 30394829 )
2019
7
Cerebral venous sinus thrombosis due to hyperhomocysteinemia with cystathionine-β-synthase (CBS) gene mutation: A case report. ( 30732165 )
2019
8
Accumulation of Tau Protein, Metabolism and Perfusion-Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS). ( 30837933 )
2019
9
Hyperhomocysteinemia induced endothelial progenitor cells dysfunction through hyper-methylation of CBS promoter. ( 30683311 )
2019
10
High incidence of MTHFR, CBS, and MTRR polymorphisms in vitiligo patients. Preliminary report in a retrospective study. ( 30720153 )
2019
11
Evaluation of genotyping methods and costs for MTHFR, CBS and MTRR polymorphisms in patients with vitiligo. ( 30915724 )
2019
12
Simultaneous biodegradation of mixture of carbamates by newly isolated Ascochyta sp. CBS 237.37. ( 30476821 )
2019
13
An arginine residue involved in allosteric regulation of cystathionine β-synthase (CBS) domain-containing pyrophosphatase. ( 30502330 )
2019
14
Probiotic effects of marine Debaryomyces hansenii CBS 8339 on innate immune and antioxidant parameters in newborn goats. ( 30656393 )
2019
15
Complete Genome Sequence of Caldicellulosiruptor changbaiensis CBS-Z, an Extremely Thermophilic, Cellulolytic Bacterium Isolated from a Hot Spring in China. ( 30834376 )
2019
16
CBS promoter hypermethylation increases the risk of hypertension and stroke. ( 30916171 )
2019
17
Family physician awareness of Charles Bonnet syndrome. ( 29471318 )
2018
18
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. ( 29778582 )
2018
19
Hallucinatory experiences in visually impaired individuals: Charles Bonnet syndrome - implications for research and clinical practice. ( 29930220 )
2018
20
Charles Bonnet syndrome secondary to multifocal intraocular lens implantation. ( 29891160 )
2018
21
A low dose of risperidone resolved Charles Bonnet syndrome after an unsuccessful trial of quetiapine: a case report. ( 29593414 )
2018
22
Complex visual hallucinatory experience in an elderly blind woman with glaucoma: revisiting Charles Bonnet syndrome. ( 29744073 )
2018
23
Charles Bonnet Syndrome in a Geriatric Female Patient: A Case Report. ( 29570961 )
2018
24
Charles Bonnet Syndrome and Other Hallucinatory Phenomena. ( 29145190 )
2018
25
Repetitive Transcranial Magnetic Stimulation-Induced Charles Bonnet Syndrome. ( 29980301 )
2018
26
Charles Bonnet syndrome versus Occipital Epilepsy, a diagnostic challenge. ( 29957762 )
2018
27
Gulliver's world: Persistent lilliputian hallucinations as manifestation of Charles Bonnet syndrome in a case of cataract and normal pressure hydrocephalus. ( 30405266 )
2018
28
Remission of Charles Bonnet syndrome after cataract extraction. ( 30502996 )
2018
29
Challenges of diagnosing and treating Charles Bonnet syndrome. ( 30140592 )
2018
30
Charles Bonnet syndrome. ( 30194097 )
2018
31
Charles Bonnet syndrome - disturbing 'playthings of the brain'. ( 30224367 )
2018
32
Charles Bonnet Syndrome: Cortical Hyperexcitability and Visual Hallucination. ( 30399348 )
2018
33
Ave Maria and Visions of Children: Atypical Charles Bonnet Syndrome or Two Coexisting Deafferentation Phenomena? ( 30402359 )
2018
34
CBS mutations are good predictors for B6-responsiveness: A study based on the analysis of 35 Brazilian Classical Homocystinuria patients. ( 30264510 )
2018
35
Data on whole genome sequencing of the oomycete Pythium insidiosum strain CBS 101555 from a horse with pythiosis in Brazil. ( 30537981 )
2018
36
CBS mutations and MTFHR SNPs causative of hyperhomocysteinemia in Pakistani children. ( 29600437 )
2018
37
Impaired CBS-H2S signaling axis contributes to MPTP-induced neurodegeneration in a mouse model of Parkinson's disease. ( 28774789 )
2018
38
Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates. ( 28900755 )
2018
39
Enzymatic Hydrolysis of Black Liquor Xylan by a Novel Xylose-Tolerant, Thermostable β-Xylosidase from a Tropical Strain of Aureobasidium pullulans CBS 135684. ( 28918541 )
2018
40
Erratum to: Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates. ( 29027144 )
2018
41
Mating-type switching in CBS 732T derived subcultures unveils potential genetic and phenotypic novelties in haploid Zygosaccharomyces rouxii. ( 29228275 )
2018
42
Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS). ( 29254576 )
2018
43
Draft Genome Sequence of Saccharomycopsis fermentans CBS 7830, a Predacious Yeast Belonging to the Saccharomycetales. ( 29326220 )
2018
44
Draft Genome Sequence of the Sordariomycete Lecythophora (Coniochaeta) hoffmannii CBS 245.38. ( 29449401 )
2018
45
Enhancing the catalytic activity of a novel GH5 cellulase GtCel5 from Gloeophyllum trabeum CBS 900.73 by site-directed mutagenesis on loop 6. ( 29588661 )
2018
46
Toward High-Level Theoretical Studies of Large Biodiesel Molecules: An ONIOM [QCISD(T)/CBS:DFT] Study of the Reactions between Unsaturated Methyl Esters (C nH2 n-1COOCH3) and Hydrogen Radical. ( 29745664 )
2018
47
Optimized yeast-based in vitro bioassay for determination of estrogenic and androgenic activity of hydroxylated / methoxylated metabolites of BDEs / CBs and related lipophilic organic pollutants. ( 29775424 )
2018
48
MiR-125b-5p is involved in oxygen and glucose deprivation injury in PC-12 cells via CBS/H2S pathway. ( 29777774 )
2018
49
Pd NP-Loaded and Covalently Cross-Linked COF Membrane Microreactor for Aqueous CBs Dechlorination at Room Temperature. ( 29847916 )
2018
50
Gene expression microarray data from mouse CBS treated with rTMS for 30 days, mouse cerebrum and CBS treated with rTMS for 40 days. ( 29876464 )
2018

Variations for Charles Bonnet Syndrome

Expression for Charles Bonnet Syndrome

Search GEO for disease gene expression data for Charles Bonnet Syndrome.

Pathways for Charles Bonnet Syndrome

GO Terms for Charles Bonnet Syndrome

Sources for Charles Bonnet Syndrome

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