CBS
MCID: CHR158
MIFTS: 23

Charles Bonnet Syndrome (CBS)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Charles Bonnet Syndrome

MalaCards integrated aliases for Charles Bonnet Syndrome:

Name: Charles Bonnet Syndrome 52 71
Cbs 52

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 71 C0339731

Summaries for Charles Bonnet Syndrome

NIH Rare Diseases : 52 Charles Bonnet syndrome (CBS) is a disease in which visual hallucinations occur as a result of vision loss. CBS is not thought to be related to psychosis or dementia and people with CBS are aware that their hallucinations are not real. The hallucinations people with CBS experience can be described as simple or complex. Simple hallucinations include shapes and patterns, while complex include images of people, vehicles, animals, and plants. Hallucination episodes can range from a few seconds to hours and may recur over the course of several days to years. The cause of CBS is not well understood, but it is thought to be related to the brain continuing to interpret images, even in their absence. There are many underlying diseases of vision loss that are associated with CBS, such as macular degeneration and stroke. Hallucinations may resolve in instances where the the underlying vision issue can be corrected (such as with cataracts ). Treatment differs depending on the impact symptoms have on a person's life. Some people are taught to block their hallucinations, while others may benefit from antipsychotic medications.

MalaCards based summary : Charles Bonnet Syndrome, also known as cbs, is related to homocystinuria due to cystathionine beta-synthase deficiency and homocystinuria. An important gene associated with Charles Bonnet Syndrome is HARS1 (Histidyl-TRNA Synthetase 1). Affiliated tissues include brain, liver and eye.

Wikipedia : 74 Visual release hallucinations, also known as Charles Bonnet Syndrome or CBS, are a type of... more...

Related Diseases for Charles Bonnet Syndrome

Diseases related to Charles Bonnet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 352)
# Related Disease Score Top Affiliating Genes
1 homocystinuria due to cystathionine beta-synthase deficiency 12.7
2 homocystinuria 12.5
3 homocysteinemia 12.1
4 neural tube defects 11.7
5 vascular disease 11.6
6 down syndrome 11.6
7 marfan syndrome 11.6
8 usher syndrome, type iiib 11.5
9 homocystinuria caused by cystathionine beta-synthase deficiency 11.5
10 isolated ectopia lentis 11.4
11 grange syndrome 11.4
12 wolff-parkinson-white syndrome 11.4
13 lens subluxation 11.4
14 pyridoxine deficiency anemia 11.4
15 hypermethioninemia 11.2
16 familial hypercholesterolemia 11.2
17 megakaryocytic leukemia 11.2
18 progressive supranuclear palsy-corticobasal syndrome 11.2
19 methionine adenosyltransferase i/iii deficiency 11.1
20 methylmalonic aciduria and homocystinuria, cblc type 11.1
21 glycine n-methyltransferase deficiency 11.1
22 malignant hyperthermia 11.1
23 macular degeneration, age-related, 1 10.9
24 neuroblastoma 10.8
25 cataract 10.6
26 subacute delirium 10.6
27 dementia 10.6
28 intraocular pressure quantitative trait locus 10.5
29 yemenite deaf-blind hypopigmentation syndrome 10.4
30 microvascular complications of diabetes 5 10.4
31 neuroretinitis 10.4
32 epilepsy 10.4
33 retinitis 10.4
34 retinitis pigmentosa 10.4
35 kuhnt-junius degeneration 10.4
36 optic nerve disease 10.4
37 eye disease 10.4
38 corticobasal degeneration 10.4
39 dentinogenesis imperfecta type 2 10.3
40 migraine with or without aura 1 10.3
41 3-methylglutaconic aciduria, type iii 10.3
42 meningioma, radiation-induced 10.3
43 meningioma, familial 10.3
44 spinal meningioma 10.3
45 optic neuritis 10.3
46 neuritis 10.3
47 secretory meningioma 10.3
48 lymphoplasmacyte-rich meningioma 10.3
49 hereditary optic neuropathy 10.3
50 pancreatic ductal adenocarcinoma 10.3

Graphical network of the top 20 diseases related to Charles Bonnet Syndrome:



Diseases related to Charles Bonnet Syndrome

Symptoms & Phenotypes for Charles Bonnet Syndrome

Drugs & Therapeutics for Charles Bonnet Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Control Trial of Patients With a Charles Bonnet Syndrome Completed NCT03148249

Search NIH Clinical Center for Charles Bonnet Syndrome

Genetic Tests for Charles Bonnet Syndrome

Anatomical Context for Charles Bonnet Syndrome

MalaCards organs/tissues related to Charles Bonnet Syndrome:

40
Brain, Liver, Eye, Bone, Pituitary, Heart, Temporal Lobe

Publications for Charles Bonnet Syndrome

Articles related to Charles Bonnet Syndrome:

(show top 50) (show all 390)
# Title Authors PMID Year
1
[Visual hallucinations in the works of Oliver Sacks]. 61
31930472 2020
2
CLINICAL CHARACTERISTICS OF THE CHARLES BONNET SYNDROME IN PATIENTS WITH NEOVASCULAR-AGE RELATED MACULAR DEGENERATION: THE IMPORTANCE OF EARLY DETECTION. 61
31986513 2020
3
Charles Bonnet Syndrome in a Patient with Parkinson's Disease and Bilateral Posterior Capsule Opacification. 61
32021492 2020
4
Evaluation of the Clinical Features, Management, and Prognoses of Patients With Charles Bonnet Syndrome. 61
31703034 2019
5
Functional MRI study in a case of Charles Bonnet syndrome related to LHON. 61
31888524 2019
6
Charles Bonnet Syndrome Treated With Pimavanserin. 61
31022063 2019
7
The elephant in the room: understanding the pathogenesis of Charles Bonnet syndrome. 61
31591762 2019
8
Glycerol Used for Controlling the Increased Intracranial Pressure-Related Charles Bonnet Syndrome. 61
30839324 2019
9
The therapeutic role of repetitive transcranial magnetic stimulation (rTMS) in parkinsonian visual hallucinations: Electrophysiological correlates. 61
31477464 2019
10
Correction to: The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria. 61
31583476 2019
11
Prevalence of Charles Bonnet syndrome in patients with age-related macular degeneration: systematic review and meta-analysis. 61
31654492 2019
12
Charles Bonnet syndrome in a young patient with a history of epilepsy. 61
28081973 2019
13
Reversible Charles Bonnet syndrome secondary to upper lid ptosis. 61
31379235 2019
14
Auditory Charles Bonnet syndrome: case report. 61
31249098 2019
15
The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria. 61
31342218 2019
16
"Playthings of the Brain": Phantom Visions in Charles Bonnet Syndrome. 61
31219409 2019
17
Screening for Charles Bonnet syndrome: Should the definition be reconsidered? 61
31238427 2019
18
[Giant Cell Arteritis and Charles Bonnet Syndrome. The Case of Saint Martin of Leon]. 61
31315406 2019
19
Charles Bonnet syndrome: development and validation of a screening and multidimensional descriptive questionnaire. 61
31109471 2019
20
Alice in Wonderland Syndrome and Charles Bonnet Syndrome: Similar but not so similar! 61
30977394 2019
21
The sound of music: A rare case of auditory Charles Bonnet syndrome in an elderly male. 61
31046031 2019
22
Charles Bonnet syndrome in Leber's hereditary optic neuropathy. 61
30687896 2019
23
Charles Bonnet syndrome and periodic alternating nystagmus: Moving visual hallucinations. 61
30700594 2019
24
FDG-PET Scanning Shows Distributed Changes in Cortical Activity Associated with Visual Hallucinations in Eye Disease. 61
30160221 2019
25
Repetitive TranscranialMagnetic Stimulation-Induced Charles Bonnet Syndrome. 61
29980301 2019
26
Think sight loss, think Charles Bonnet syndrome. 61
31903448 2019
27
[Complex visual hallucinations in the visually impaired, the Charles Bonnet syndrome]. 61
30667516 2019
28
The Last Witness to Creation: A Case of Charles Bonnet Syndrome. 61
31012826 2019
29
Charles Bonnet Syndrome: so much more than just a side effect of sight loss. 61
31701085 2019
30
Resting-state functional connectivity and cortical thickness characterization of a patient with Charles Bonnet syndrome. 61
31318888 2019
31
Charles Bonnet syndrome. 61
30194097 2018
32
Remission of Charles Bonnet syndrome after cataract extraction. 61
30502996 2018
33
Charles Bonnet syndrome - disturbing 'playthings of the brain'. 61
30224367 2018
34
Hallucinations in an Elderly Patient with Severe Visual Impairment. 61
30675446 2018
35
Stimulus-Driven Cortical Hyperexcitability in Individuals with Charles Bonnet Hallucinations. 61
30415703 2018
36
Charles Bonnet Syndrome: Cortical Hyperexcitability and Visual Hallucination. 61
30399348 2018
37
[Musical Hallucinosis]. 61
30416107 2018
38
Rare and rarer: co-occurrence of stroke-like migraine attacks after radiation therapy and Charles Bonnet syndromes. 61
30323940 2018
39
Reversible Charles Bonnet Syndrome After Oculoplastic Procedures. 61
27984353 2018
40
Family physician awareness of Charles Bonnet syndrome. 61
29471318 2018
41
Charles Bonnet syndrome secondary to hypertensive crisis. 61
27296495 2018
42
Challenges of diagnosing and treating Charles Bonnet syndrome. 61
30140592 2018
43
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. 61
29778582 2018
44
Ave Maria and Visions of Children: Atypical Charles Bonnet Syndrome or Two Coexisting Deafferentation Phenomena? 61
30402359 2018
45
Gulliver's world: Persistent lilliputian hallucinations as manifestation of Charles Bonnet syndrome in a case of cataract and normal pressure hydrocephalus. 61
30405266 2018
46
Charles Bonnet syndrome versus Occipital Epilepsy, a diagnostic challenge. 61
29957762 2018
47
Hallucinatory experiences in visually impaired individuals: Charles Bonnet syndrome - implications for research and clinical practice. 61
29930220 2018
48
Complex visual hallucinatory experience in an elderly blind woman with glaucoma: revisiting Charles Bonnet syndrome. 61
29744073 2018
49
Charles Bonnet syndrome secondary to multifocal intraocular lens implantation. 61
29891160 2018
50
Low vision rehabilitation: An update. 61
29942183 2018

Variations for Charles Bonnet Syndrome

Expression for Charles Bonnet Syndrome

Search GEO for disease gene expression data for Charles Bonnet Syndrome.

Pathways for Charles Bonnet Syndrome

GO Terms for Charles Bonnet Syndrome

Sources for Charles Bonnet Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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