CBS
MCID: CHR158
MIFTS: 23

Charles Bonnet Syndrome (CBS)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Charles Bonnet Syndrome

MalaCards integrated aliases for Charles Bonnet Syndrome:

Name: Charles Bonnet Syndrome 53 72
Cbs 53

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 72 C0339731

Summaries for Charles Bonnet Syndrome

NIH Rare Diseases : 53 Charles Bonnet syndrome (CBS) is a disease in which visual hallucinations occur as a result of vision loss. CBS is not thought to be related to psychosis or dementia and people with CBS are aware that their hallucinations are not real. The hallucinations people with CBS experience can be described as simple or complex. Simple hallucinations include shapes and patterns, while complex include images of people, vehicles, animals, and plants. Hallucination episodes can range from a few seconds to hours and may recur over the course of several days to years. The cause of CBS is not well understood, but it is thought to be related to the brain continuing to interpret images, even in their absence. There are many underlying diseases of vision loss that are associated with CBS, such as macular degeneration and stroke. Hallucinations may resolve in instances where the the underlying vision issue can be corrected (such as with cataracts). Treatment differs depending on the impact symptoms have on a person's life. Some people are taught to block their hallucinations, while others may benefit from antipsychotic medications.

MalaCards based summary : Charles Bonnet Syndrome, also known as cbs, is related to homocystinuria due to cbs deficiency and homocystinuria due to cystathionine beta-synthase deficiency. An important gene associated with Charles Bonnet Syndrome is HARS1 (Histidyl-TRNA Synthetase 1). Affiliated tissues include brain, eye and occipital lobe.

Wikipedia : 75 Visual release hallucinations, known as Charles Bonnet Syndrome, are a type of psychophysical visual... more...

Related Diseases for Charles Bonnet Syndrome

Diseases related to Charles Bonnet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 356)
# Related Disease Score Top Affiliating Genes
1 homocystinuria due to cbs deficiency 13.0
2 homocystinuria due to cystathionine beta-synthase deficiency 12.6
3 homocystinuria 12.5
4 homocysteinemia 12.1
5 marfan syndrome 11.7
6 neural tube defects 11.7
7 homocystinuria caused by cystathionine beta-synthase deficiency 11.6
8 vascular disease 11.6
9 isolated ectopia lentis 11.6
10 grange syndrome 11.6
11 wolff-parkinson-white syndrome 11.6
12 lens subluxation 11.6
13 pyridoxine deficiency anemia 11.6
14 usher syndrome, type iiib 11.5
15 hypermethioninemia 11.3
16 megakaryocytic leukemia 11.3
17 methionine adenosyltransferase i/iii deficiency 11.3
18 methylmalonic aciduria and homocystinuria, cblc type 11.3
19 glycine n-methyltransferase deficiency 11.3
20 familial hypercholesterolemia 11.3
21 progressive supranuclear palsy-corticobasal syndrome 11.2
22 macular degeneration, age-related, 1 10.9
23 cataract 10.6
24 subacute delirium 10.6
25 dementia 10.6
26 intraocular pressure quantitative trait locus 10.5
27 yemenite deaf-blind hypopigmentation syndrome 10.4
28 microvascular complications of diabetes 5 10.4
29 neuroretinitis 10.4
30 epilepsy 10.4
31 retinitis 10.4
32 retinitis pigmentosa 10.4
33 eye disease 10.4
34 corticobasal degeneration 10.3
35 pancreatic ductal adenocarcinoma 10.3
36 dentinogenesis imperfecta type 2 10.3
37 migraine with or without aura 1 10.3
38 meningioma, radiation-induced 10.3
39 meningioma, familial 10.3
40 kuhnt-junius degeneration 10.3
41 spinal meningioma 10.3
42 optic neuritis 10.3
43 neuritis 10.3
44 optic nerve disease 10.3
45 secretory meningioma 10.3
46 lymphoplasmacyte-rich meningioma 10.3
47 pertussis 10.3
48 multiple sclerosis 10.2
49 temporal arteritis 10.2
50 3-methylglutaconic aciduria, type iii 10.2

Graphical network of the top 20 diseases related to Charles Bonnet Syndrome:



Diseases related to Charles Bonnet Syndrome

Symptoms & Phenotypes for Charles Bonnet Syndrome

Drugs & Therapeutics for Charles Bonnet Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Control Trial of Patients With a Charles Bonnet Syndrome Completed NCT03148249

Search NIH Clinical Center for Charles Bonnet Syndrome

Genetic Tests for Charles Bonnet Syndrome

Anatomical Context for Charles Bonnet Syndrome

MalaCards organs/tissues related to Charles Bonnet Syndrome:

41
Brain, Eye, Occipital Lobe, Pituitary, Cortex, Thalamus, Temporal Lobe

Publications for Charles Bonnet Syndrome

Articles related to Charles Bonnet Syndrome:

(show top 50) (show all 379)
# Title Authors PMID Year
1
Reversible Charles Bonnet syndrome secondary to upper lid ptosis. 38
31379235 2019
2
Auditory Charles Bonnet syndrome: case report. 38
31249098 2019
3
The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria. 38
31342218 2019
4
Screening for Charles Bonnet syndrome: Should the definition be reconsidered? 38
31238427 2019
5
"Playthings of the Brain": Phantom Visions in Charles Bonnet Syndrome. 38
31219409 2019
6
[Giant Cell Arteritis and Charles Bonnet Syndrome. The Case of Saint Martin of Leon]. 38
31315406 2019
7
Alice in Wonderland Syndrome and Charles Bonnet Syndrome: Similar but not so similar! 38
30977394 2019
8
Charles Bonnet syndrome: development and validation of a screening and multidimensional descriptive questionnaire. 38
31109471 2019
9
The sound of music: A rare case of auditory Charles Bonnet syndrome in an elderly male. 38
31046031 2019
10
Charles Bonnet Syndrome Treated With Pimavanserin. 38
31022063 2019
11
Charles Bonnet syndrome and periodic alternating nystagmus: Moving visual hallucinations. 38
30700594 2019
12
Charles Bonnet syndrome in Leber's hereditary optic neuropathy. 38
30687896 2019
13
Glycerol Used for Controlling the Increased Intracranial Pressure-Related Charles Bonnet Syndrome. 38
30839324 2019
14
The Last Witness to Creation: A Case of Charles Bonnet Syndrome. 38
31012826 2019
15
Resting-state functional connectivity and cortical thickness characterization of a patient with Charles Bonnet syndrome. 38
31318888 2019
16
FDG-PET Scanning Shows Distributed Changes in Cortical Activity Associated with Visual Hallucinations in Eye Disease. 38
30160221 2019
17
[Complex visual hallucinations in the visually impaired, the Charles Bonnet syndrome]. 38
30667516 2019
18
Repetitive TranscranialMagnetic Stimulation-Induced Charles Bonnet Syndrome. 38
29980301 2019
19
Charles Bonnet syndrome. 38
30194097 2018
20
Remission of Charles Bonnet syndrome after cataract extraction. 38
30502996 2018
21
Charles Bonnet syndrome - disturbing 'playthings of the brain'. 38
30224367 2018
22
Hallucinations in an Elderly Patient with Severe Visual Impairment. 38
30675446 2018
23
Stimulus-Driven Cortical Hyperexcitability in Individuals with Charles Bonnet Hallucinations. 38
30415703 2018
24
Charles Bonnet Syndrome: Cortical Hyperexcitability and Visual Hallucination. 38
30399348 2018
25
[Musical Hallucinosis]. 38
30416107 2018
26
Rare and rarer: co-occurrence of stroke-like migraine attacks after radiation therapy and Charles Bonnet syndromes. 38
30323940 2018
27
Reversible Charles Bonnet Syndrome After Oculoplastic Procedures. 38
27984353 2018
28
Charles Bonnet syndrome secondary to hypertensive crisis. 38
27296495 2018
29
Family physician awareness of Charles Bonnet syndrome. 38
29471318 2018
30
Challenges of diagnosing and treating Charles Bonnet syndrome. 38
30140592 2018
31
When Post-Traumatic Stress Disorder and Charles Bonnet Syndrome Become Lewy Body Dementia. 38
29778582 2018
32
Ave Maria and Visions of Children: Atypical Charles Bonnet Syndrome or Two Coexisting Deafferentation Phenomena? 38
30402359 2018
33
Gulliver's world: Persistent lilliputian hallucinations as manifestation of Charles Bonnet syndrome in a case of cataract and normal pressure hydrocephalus. 38
30405266 2018
34
Hallucinatory experiences in visually impaired individuals: Charles Bonnet syndrome - implications for research and clinical practice. 38
29930220 2018
35
Charles Bonnet syndrome versus Occipital Epilepsy, a diagnostic challenge. 38
29957762 2018
36
Complex visual hallucinatory experience in an elderly blind woman with glaucoma: revisiting Charles Bonnet syndrome. 38
29744073 2018
37
Charles Bonnet syndrome secondary to multifocal intraocular lens implantation. 38
29891160 2018
38
Low vision rehabilitation: An update. 38
29942183 2018
39
Charles Bonnet Syndrome in a Geriatric Female Patient: A Case Report. 38
29570961 2018
40
Pseudo-Charles Bonnet Syndrome With a Frontal Tumor: Visual Hallucinations, the Brain, and the Two-Hit Hypothesis. 38
28774226 2018
41
Cognitive impairment and Charles Bonnet syndrome: a prospective study. 38
28117918 2018
42
Charles Bonnet Syndrome and Other Hallucinatory Phenomena. 38
29145190 2018
43
Closed-Eye Visualizations in the Setting of Hyponatremia. 38
29560008 2018
44
A low dose of risperidone resolved Charles Bonnet syndrome after an unsuccessful trial of quetiapine: a case report. 38
29593414 2018
45
Visual acuity and contrast sensitivity are two important factors affecting vision-related quality of life in advanced age-related macular degeneration. 38
29746512 2018
46
The Charles Bonnet Syndrome in Patients With Neovascular Age-Related Macular Degeneration: Association With Proton Pump Inhibitors. 38
28829845 2017
47
Charles Bonnet syndrome in a child with congenital glaucoma. 38
28038923 2017
48
Keep an eye out: A rare case of acute-onset Charles Bonnet Syndrome after Stanford type A aortic dissection repair surgery. 38
28670981 2017
49
Charles Bonnet Syndrome Following Eyelid Reconstruction Surgery. 38
28475529 2017
50
Multimodal Hallucinations in a Visually Impaired Elderly Female: Is it a Variant of Charles Bonnet Syndrome? 38
28615779 2017

Variations for Charles Bonnet Syndrome

Expression for Charles Bonnet Syndrome

Search GEO for disease gene expression data for Charles Bonnet Syndrome.

Pathways for Charles Bonnet Syndrome

GO Terms for Charles Bonnet Syndrome

Sources for Charles Bonnet Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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