MCID: CHM005
MIFTS: 23

Chemical Colitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Chemical Colitis

MalaCards integrated aliases for Chemical Colitis:

Name: Chemical Colitis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060186
ICD10 33 K52
ICD9CM 35 558 558.9
UMLS 73 C0029512

Summaries for Chemical Colitis

Disease Ontology : 12 A colitis caused_by introduction of various chemicals.

MalaCards based summary : Chemical Colitis is related to colitis and pulmonary hypertension. An important gene associated with Chemical Colitis is VIP (Vasoactive Intestinal Peptide), and among its related pathways/superpathways is G alpha (s) signalling events. Affiliated tissues include colon, and related phenotypes are Lamellipodia cells and homeostasis/metabolism

Wikipedia : 76 Chemical colitis is a type of colitis, an inflammation of the large intestine or colon, caused by the... more...

Related Diseases for Chemical Colitis

Diseases related to Chemical Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 colitis 10.3
2 pulmonary hypertension 9.8 PTGIR VIP
3 ischemic colitis 9.7

Symptoms & Phenotypes for Chemical Colitis

GenomeRNAi Phenotypes related to Chemical Colitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Lamellipodia cells GR00165-A 8.8 CASP1 NOG RSPO1

MGI Mouse Phenotypes related to Chemical Colitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 ATOH1 CASP1 NOG PTGIR RSPO1 VIP
2 endocrine/exocrine gland MP:0005379 9.72 ATOH1 CASP1 NOG RSPO1 VIP
3 integument MP:0010771 9.55 ATOH1 CASP1 NOG PTGIR RSPO1
4 mortality/aging MP:0010768 9.43 ATOH1 CASP1 NOG PTGIR RSPO1 VIP
5 reproductive system MP:0005389 8.92 CASP1 NOG RSPO1 VIP

Drugs & Therapeutics for Chemical Colitis

Search Clinical Trials , NIH Clinical Center for Chemical Colitis

Genetic Tests for Chemical Colitis

Anatomical Context for Chemical Colitis

MalaCards organs/tissues related to Chemical Colitis:

41
Colon

Publications for Chemical Colitis

Articles related to Chemical Colitis:

(show all 19)
# Title Authors Year
1
Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review. ( 29631344 )
2018
2
Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review. ( 28111419 )
2016
3
Validation of a modified model of TNBS-induced colitis in rats. How to induce a chemical colitis in rats. ( 25948034 )
2015
4
Enhanced excitability of guinea pig ileum myenteric AH neurons during and following recovery from chemical colitis. ( 23628671 )
2013
5
Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis. ( 22815676 )
2012
6
Severe chemical colitis due to hydrogen peroxide enema. ( 21857533 )
2012
7
Enhanced excitability of guinea pig inferior mesenteric ganglion neurons during and following recovery from chemical colitis. ( 22961805 )
2012
8
Glutaraldehyde-induced chemical colitis versus ischemic colitis. ( 20155321 )
2010
9
Chemical colitis caused by peracetic acid or hydrogen peroxide: a challenging dilemma. ( 20066605 )
2010
10
Chemical colitis from a hydrogen peroxide enema. ( 21365964 )
2010
11
Chemical colitis due to glutaraldehyde: case series and review of the literature. ( 19104938 )
2009
12
Chemical colitis induced by peracetic acid: further evidence. ( 19340747 )
2009
13
Chemical colitis. ( 18209577 )
2008
14
Urocortin 2 expression in the rat gastrointestinal tract under basal conditions and in chemical colitis. ( 17586086 )
2007
15
Acute chemical colitis resulting from oral intake of henna. ( 16208120 )
2005
16
Changes of colonic vasoactive intestinal peptide and cholinergic activity in rats with chemical colitis. ( 1425074 )
1992
17
Mucosal plaques seen at colonoscopy: chemical colitis or mucosal pseudolipomatosis? ( 2714588 )
1989
18
Chemical colitis due to endoscope cleaning solutions: a mimic of pseudomembranous colitis. ( 3169504 )
1988
19
Fiberoptic colonoscopic study of experimental chemical colitis. ( 7390105 )
1980

Variations for Chemical Colitis

Expression for Chemical Colitis

Search GEO for disease gene expression data for Chemical Colitis.

Pathways for Chemical Colitis

Pathways related to Chemical Colitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.79 PTGIR VIP

GO Terms for Chemical Colitis

Biological processes related to Chemical Colitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 central nervous system development GO:0007417 9.16 ATOH1 NOG
2 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 8.96 PTGIR VIP
3 negative regulation of smooth muscle cell proliferation GO:0048662 8.62 PTGIR VIP

Sources for Chemical Colitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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