MCID: CHM005
MIFTS: 23

Chemical Colitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Chemical Colitis

MalaCards integrated aliases for Chemical Colitis:

Name: Chemical Colitis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060186
ICD9CM 35 558 558.9
ICD10 33 K52
UMLS 72 C0029512

Summaries for Chemical Colitis

Disease Ontology : 12 A colitis caused by introduction of various chemicals.

MalaCards based summary : Chemical Colitis is related to colitis and ischemic colitis. An important gene associated with Chemical Colitis is VIP (Vasoactive Intestinal Peptide). Affiliated tissues include colon, brain and small intestine, and related phenotypes are Lamellipodia cells and homeostasis/metabolism

Wikipedia : 75 Chemical colitis is a type of colitis, an inflammation of the large intestine or colon, caused by the... more...

Related Diseases for Chemical Colitis

Diseases related to Chemical Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 colitis 10.4
2 ischemic colitis 10.0
3 inflammatory bowel disease 9.9
4 clostridium difficile colitis 9.7
5 constipation 9.7
6 intestinal disease 9.7
7 peritonitis 9.7
8 ulcerative colitis 9.7

Graphical network of the top 20 diseases related to Chemical Colitis:



Diseases related to Chemical Colitis

Symptoms & Phenotypes for Chemical Colitis

GenomeRNAi Phenotypes related to Chemical Colitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Lamellipodia cells GR00165-A 8.8 CASP1 NOG RSPO1

MGI Mouse Phenotypes related to Chemical Colitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 ATOH1 CASP1 NOG NR1I2 RSPO1 VIP
2 endocrine/exocrine gland MP:0005379 9.72 ATOH1 CASP1 NOG RSPO1 VIP
3 integument MP:0010771 9.46 ATOH1 CASP1 NOG RSPO1
4 mortality/aging MP:0010768 9.43 ATOH1 CASP1 NOG NR1I2 RSPO1 VIP
5 reproductive system MP:0005389 9.02 CASP1 NOG NR1I2 RSPO1 VIP

Drugs & Therapeutics for Chemical Colitis

Search Clinical Trials , NIH Clinical Center for Chemical Colitis

Genetic Tests for Chemical Colitis

Anatomical Context for Chemical Colitis

MalaCards organs/tissues related to Chemical Colitis:

41
Colon, Brain, Small Intestine, Endothelial

Publications for Chemical Colitis

Articles related to Chemical Colitis:

(show all 50)
# Title Authors PMID Year
1
The recruitment of extra-intestinal cells to the injured mucosa promotes healing in radiation enteritis and chemical colitis in a mouse parabiosis model. 38
30617302 2019
2
Fluid supplementation accelerates epithelial repair during chemical colitis. 38
31002683 2019
3
Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration. 38
30100168 2018
4
Expression and characterization of αvβ5 integrin on intestinal macrophages. 38
29676784 2018
5
Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer. 38
29768197 2018
6
Exercise training-induced modification of the gut microbiota persists after microbiota colonization and attenuates the response to chemically-induced colitis in gnotobiotic mice. 38
28862530 2018
7
Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice. 38
29760697 2018
8
The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis. 38
29545807 2018
9
Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review. 38
29631344 2018
10
Mast Cells Exert Anti-Inflammatory Effects in an IL10-/- Model of Spontaneous Colitis. 38
29849494 2018
11
Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review. 38
28111419 2016
12
Id1 expression in endothelial cells of the colon is required for normal response to injury. 38
26348574 2015
13
Validation of a modified model of TNBS-induced colitis in rats. How to induce a chemical colitis in rats. 38
25948034 2015
14
Transcriptional corepressor MTG16 regulates small intestinal crypt proliferation and crypt regeneration after radiation-induced injury. 38
25573176 2015
15
In vivo imaging of reactive oxygen and nitrogen species in murine colitis. 38
24983980 2014
16
Interleukin-37. 38
24275599 2013
17
Dynamic changes of peritoneal macrophages and subpopulations during ulcerative colitis to metastasis of colorectal carcinoma in a mouse model. 38
23625042 2013
18
Enhanced excitability of guinea pig ileum myenteric AH neurons during and following recovery from chemical colitis. 38
23628671 2013
19
[Chemical colitis due to hydrogen peroxide enema]. 38
23566413 2013
20
Enhanced excitability of guinea pig inferior mesenteric ganglion neurons during and following recovery from chemical colitis. 38
22961805 2012
21
Colonic mucosal pseudolipomatosis: disinfectant colitis? 38
22647801 2012
22
Severe chemical colitis due to hydrogen peroxide enema. 38
21857533 2012
23
Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis. 38
22815676 2012
24
[A case of chemical colitis caused by hydrogen peroxide enema]. 38
21873825 2011
25
The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication. 38
21988661 2011
26
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. 38
21565393 2011
27
A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents. 38
21181946 2011
28
Chemical colitis from a hydrogen peroxide enema. 38
21365964 2010
29
Glutaraldehyde-induced chemical colitis versus ischemic colitis. 38
20155321 2010
30
Chemical colitis caused by peracetic acid or hydrogen peroxide: a challenging dilemma. 38
20066605 2010
31
Chemical colitis due to glutaraldehyde: case series and review of the literature. 38
19104938 2009
32
Chemical colitis induced by peracetic acid: further evidence. 38
19340747 2009
33
Chemical colitis. 38
18209577 2008
34
Urocortin 2 expression in the rat gastrointestinal tract under basal conditions and in chemical colitis. 38
17586086 2007
35
Immunomodulatory effects of ciprofloxacin in TNBS-induced colitis in mice. 38
17253612 2007
36
[A case of idiopathic colitis developed after barium enema]. 38
16498283 2006
37
Inhibitory effect of experimental colitis on fluid absorption in rat jejunum: role of the enteric nervous system, VIP, and nitric oxide. 38
16123200 2006
38
Acute chemical colitis resulting from oral intake of henna. 38
16208120 2005
39
Favorable response to subcutaneous administration of infliximab in rats with experimental colitis. 38
16425394 2005
40
Caustic burns of rectum and colon in emergencies. 38
15191876 2004
41
Effect of DA-6034, a derivative of flavonoid, on experimental animal models of inflammatory bowel disease. 38
10489873 1999
42
Antiinflammatory effects of human milk on chemically induced colitis in rats. 38
9357937 1997
43
[Chemical colitis caused by glutaraldehyde]. 38
9113148 1997
44
Experimental colitis in rats induces low-grade endotoxinemia without hepatobiliary abnormalities. 38
8200252 1994
45
Changes of colonic vasoactive intestinal peptide and cholinergic activity in rats with chemical colitis. 38
1425074 1992
46
The effect of essential fatty acid deficiency on eicosanoid production in the inflamed rat colonic mucosa. 38
2177899 1990
47
Mucosal plaques seen at colonoscopy: chemical colitis or mucosal pseudolipomatosis? 38
2714588 1989
48
Chemical colitis due to endoscope cleaning solutions: a mimic of pseudomembranous colitis. 38
3169504 1988
49
Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. 38
6574081 1983
50
Fiberoptic colonoscopic study of experimental chemical colitis. 38
7390105 1980

Variations for Chemical Colitis

Expression for Chemical Colitis

Search GEO for disease gene expression data for Chemical Colitis.

Pathways for Chemical Colitis

GO Terms for Chemical Colitis

Biological processes related to Chemical Colitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon guidance GO:0007411 8.96 NOG ATOH1
2 central nervous system development GO:0007417 8.62 NOG ATOH1

Sources for Chemical Colitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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