MCID: CHM005
MIFTS: 23

Chemical Colitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Chemical Colitis

MalaCards integrated aliases for Chemical Colitis:

Name: Chemical Colitis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060186
ICD9CM 36 558 558.9
ICD10 34 K52
UMLS 74 C0029512

Summaries for Chemical Colitis

Disease Ontology : 12 A colitis caused_by introduction of various chemicals.

MalaCards based summary : Chemical Colitis is related to colitis and ischemic colitis. An important gene associated with Chemical Colitis is VIP (Vasoactive Intestinal Peptide), and among its related pathways/superpathways is G alpha (s) signalling events. Affiliated tissues include colon, and related phenotypes are Lamellipodia cells and homeostasis/metabolism

Wikipedia : 77 Chemical colitis is a type of colitis, an inflammation of the large intestine or colon, caused by the... more...

Related Diseases for Chemical Colitis

Diseases related to Chemical Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 colitis 10.4
2 ischemic colitis 9.7
3 clostridium difficile colitis 9.7
4 pulmonary hypertension 9.7 PTGIR VIP

Symptoms & Phenotypes for Chemical Colitis

GenomeRNAi Phenotypes related to Chemical Colitis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Lamellipodia cells GR00165-A 8.8 CASP1 NOG RSPO1

MGI Mouse Phenotypes related to Chemical Colitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 ATOH1 CASP1 NOG PTGIR RSPO1 VIP
2 endocrine/exocrine gland MP:0005379 9.72 ATOH1 CASP1 NOG RSPO1 VIP
3 integument MP:0010771 9.55 ATOH1 CASP1 NOG PTGIR RSPO1
4 mortality/aging MP:0010768 9.43 ATOH1 CASP1 NOG PTGIR RSPO1 VIP
5 reproductive system MP:0005389 8.92 CASP1 NOG RSPO1 VIP

Drugs & Therapeutics for Chemical Colitis

Search Clinical Trials , NIH Clinical Center for Chemical Colitis

Genetic Tests for Chemical Colitis

Anatomical Context for Chemical Colitis

MalaCards organs/tissues related to Chemical Colitis:

42
Colon

Publications for Chemical Colitis

Articles related to Chemical Colitis:

(show all 21)
# Title Authors Year
1
The recruitment of extra-intestinal cells to the injured mucosa promotes healing in radiation enteritis and chemical colitis in a mouse parabiosis model. ( 30617302 )
2019
2
Fluid supplementation accelerates epithelial repair during chemical colitis. ( 31002683 )
2019
3
Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review. ( 29631344 )
2018
4
Chemical colitis caused by hydrogen peroxide enema in a child: case report and literature review. ( 28111419 )
2016
5
Validation of a modified model of TNBS-induced colitis in rats. How to induce a chemical colitis in rats. ( 25948034 )
2015
6
Enhanced excitability of guinea pig ileum myenteric AH neurons during and following recovery from chemical colitis. ( 23628671 )
2013
7
Severe chemical colitis due to hydrogen peroxide enema. ( 21857533 )
2012
8
Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis. ( 22815676 )
2012
9
Enhanced excitability of guinea pig inferior mesenteric ganglion neurons during and following recovery from chemical colitis. ( 22961805 )
2012
10
Chemical colitis caused by peracetic acid or hydrogen peroxide: a challenging dilemma. ( 20066605 )
2010
11
Glutaraldehyde-induced chemical colitis versus ischemic colitis. ( 20155321 )
2010
12
Chemical colitis from a hydrogen peroxide enema. ( 21365964 )
2010
13
Chemical colitis due to glutaraldehyde: case series and review of the literature. ( 19104938 )
2009
14
Chemical colitis induced by peracetic acid: further evidence. ( 19340747 )
2009
15
Chemical colitis. ( 18209577 )
2008
16
Urocortin 2 expression in the rat gastrointestinal tract under basal conditions and in chemical colitis. ( 17586086 )
2007
17
Acute chemical colitis resulting from oral intake of henna. ( 16208120 )
2005
18
Changes of colonic vasoactive intestinal peptide and cholinergic activity in rats with chemical colitis. ( 1425074 )
1992
19
Mucosal plaques seen at colonoscopy: chemical colitis or mucosal pseudolipomatosis? ( 2714588 )
1989
20
Chemical colitis due to endoscope cleaning solutions: a mimic of pseudomembranous colitis. ( 3169504 )
1988
21
Fiberoptic colonoscopic study of experimental chemical colitis. ( 7390105 )
1980

Variations for Chemical Colitis

Expression for Chemical Colitis

Search GEO for disease gene expression data for Chemical Colitis.

Pathways for Chemical Colitis

Pathways related to Chemical Colitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.79 PTGIR VIP

GO Terms for Chemical Colitis

Biological processes related to Chemical Colitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon guidance GO:0007411 9.26 ATOH1 NOG
2 central nervous system development GO:0007417 9.16 ATOH1 NOG
3 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 8.96 PTGIR VIP
4 negative regulation of smooth muscle cell proliferation GO:0048662 8.62 PTGIR VIP

Sources for Chemical Colitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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